ZhihengHeMDPhD

PubMed

• 291 citations
  Hyperglycemia promotes oxidative stress through inhibition of thioredoxin function by thioredoxin-interacting protein
  P. Christian Schulze, Jun Yoshioka, Tomosaburo Takahashi, Zhiheng He, George L. King
  The Journal of Biological Chemistry. 2004-07-16
• 163 citations
  Biological activities and signaling pathways of the granulin/epithelin precursor.
  Tommaso Zanocco-Marani, Andrew Bateman, Gaetano Romano, Barbara Valentinis, Zhiheng He
  Cancer Research. 1999-10-15
• 397 citations
  Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis
  Zhiheng He, Andrew Bateman
  Journal of Molecular Medicine. 2003-08-19

Journal Articles

• Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and i...  
  He, Zhiheng, ATVB
• Modulating Notch Signaling to Enhance Neovascularization and Reperfusion in Diabetic Mice  
  Cao L., Arany P., Kim J., Rivera-Feliciano J., Wang YS, He Z, Rask-Madsen C., King GL, Mooney DJ., Biomaterials, 1/1/2010
• Phosphinositide 3 Kinase Akt Signalling Pathway Interacts with Protein Kinase Cbeta2 in the Regulation of Physiologic Developmental Hypertrophy and Heart Function  
  Rigor DL, Bodyak N, Bae S, Choi JH, Zhang L, Ter-Ovanesyan D, He Z, McMullen JR, Shioi T, Izumo S, King GL, Kang PM, American Journal of Physiology, Heart and Circulatory Physiology, 1/1/2009
• Selective Regulation of Heme Oxygenase-1 Expression and Function by Insulin through IRS1/PI3-kinase/AKT-2 Pathway  
  Geraldes P, Yagi K, Ohshiro Y, He Z, Maeno Y, Yamamoto-Hiraoka J, Rask-Madsen C, Chung SW, Perrella MA, King GL, Journal of Biological Chemistry, 1/1/2008
• Regulation of Suppressor of Cytokine Signalling 2 Expression by Insulin and Its Inhibitory Actions on IGF-1's Mitogenic Effect in Renal Mesangial Cells  
  Isshiki K*, He Z*, Maeno Y, Yasuda Y, Kuroki T, Ma RC, White GS, Patti ME. Weir GC, and King GL, Kidney International, 1/1/2008
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  Arikawa E, Ma RC, Isshiki K, Luptak I, He Z, Yasuda Y, Maeno Y, Patti ME, Weir GC, Harris RA, Zammit VA, Tian R, and King GL, Diabetes, 1/1/2007
• Differential Expression of Human Telomerase Catalytic Subunit MRNA by in Situ Hybridization in Pheochromocytomas  
  Luo Z, Li J, Qin Y, Ma Y, Liang X, Xian J, Lu D, Wei M, Yang JY, Yang MQ, and He Z, Endocrine Pathology, 1/1/2006
• Regulation of Progranulin Expression in Myeloid Cells  
  Ong CH., He Z., Kriazhev L., Shan X., Palfree RG. And Bateman A., American Journal of Physiology, Regulatory, Integrative and Comparative Physiology, 1/1/2006
• Regulation of VEGF Expression and Vascularization in the Myocardium by Insulin Receptor and PI3K/Akt Pathways in Insulin Resistance and Ischemia  
  He Z., Opland DM., Way KJ., Ueki K., Bodyak N., Kang PM., Izumo S, Kulkarni RN., Wang B., Liao R., Kahn CR. and King GL., Arteriosclerosis, Thrombosis, and Vascular Biology, 1/1/2006
• Can Protein Kinase C Beta-selective Inhibitor, Ruboxistaurin, Stop Vascular Complications in Diabetic Patients?  
  He Z., King GL., Diabetes Care, 1/1/2005
• Molecular Targets of Diabetic Cardiovascular Complications  
  Ahmad FK., He Z. and King GL., Current Drug Targets, 1/1/2005
• Introduction of Hyperglycemia and Dyslipidemia in the Pathogenesis of Diabetic Vascular Complications  
  Xu Y., He Z. and King GL., Current Diabetes Reports, 1/1/2005
• PKC-isoform-dependent Regulation of CTGF Expression by Angiotensin II, Potential Mechanism for Diabetic Cardiomyopathy and Fibrosis  
  He Z., Way KJ., Arikawa E., Opland DM., Clermont A, Scott J, Feener E and King GL., Journal of Biological Chemistry, 1/1/2005
• Hyperglycemia Promotes Oxidative Stress through Inhibition of Thioredoxin Function by Thioredoxin-interacting Protein  
  Schulze PC., Yoshioka J., Takahashi T., He Z., King GL., Lee RT., Journal of Biological Chemistry, 1/1/2004
• Microvascular Complications of Diabetes  
  He Z. and King GL., Endocrinology and Metabolism Clinic of North America, 1/1/2004
• PKCbeta Isoform Inhibitors, a New Treatment for Diabetic Cardiovascular Diseases  
  He Z. and King GL., Circulation, 1/1/2004
• Characterization of Insulin's Multiple Signaling Pathways in the Regulation of Vascular Endothelial Growth Factor Expression in Vascular Cells and Angiogenesis  
  Jiang ZY., He Z., King BL., Kuroki T., Opland DM., Suzuma K., Suzuma I., Ueki K., Kulkarni RN., Kahn CR. and King GL., Journal of Biological Chemistry, 1/1/2003
• Progranulin (Acrogranin//PC Cell-derived Growth Factor/epithelin Precursor) Is Expressed in the Placenta, Epidermis, Microvasculature and Brain during Murine Development  
  Daniel R., Daniels E., He Z. and Bateman A., Developmental Dynamics, 1/1/2003
• Progranulin Is a Mediator of the Wound Response  
  He Z., Ong CHP., Halper J. and Bateman A., Nature Medicine, 1/1/2003
• Mechanisms of Cardiovascular Complications in Diabetes and Potential New Pharmacological Therapies  
  He Z., Rask-Madsen C. and King GL., European Heart Journal, 1/1/2003
• Progranulin (Granulin-epithelin Precursor, PC-cell-derived Growth Factor, Acrogranin) Mediates Tissue Repair and Tumorigenesis  
  He Z. and Bateman A., Journal of Molecular Medicine, 1/1/2003
• Progranulin (PC-cell-derived Growth Factor/acrogranin) Regulates Invasion and Cell Survival  
  He Z., Ismail A., Kriazhev L., Sadvakassova G. & Bateman A., Cancer Research, 1/1/2002
• Cellular Localization of Gene Expression for Progranulin  
  Daniel R.*, He Z.*, Paige C., Halper J. and Bateman A., Journal of Histochemistry & Cytochemistry, 1/1/2000
• Biological Activities and Signalling Pathways of the Granulin/Epithelin Precursor  
  Zanocco-Marani, T., Bateman, A., Valentinis, B., Romano, G., He, Z. and Baserga, R., Cancer Research, 1/1/1999
• Progranulin Gene Expression Regulates Epithelial Cell Growth and Promotes Tumor Growth in Vivo  
  He Z. and Bateman A., Cancer Research, 1/1/1999
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Books/Book Chapters

• Clinical Decision Support: Endocrinology 
  He Z. & Hennessey JV.Editors: Rosen CJ, Adler RA, Braverman LE and Leung A, Clemmons DR, Klibanski A, Thomas A.Decision Support in Medicine, LLC, Wilmington, DE2013
• Contemporary Cardiology, Diabetes and Cardiovascular Disease 
  Chapter: Effects of Diabetes and Insulin Resistance on Endothelial Functions 
  Page 25 - 46He Z., Naruse K. and King GL.Editors: Michael T. Johnstone and Aristidis Veves.Humana PressEdition 2nd,2005
• Diabetes and Cardiovascular Disease: Integrating Science and Clinical Medicine 
  Chapter: PKC in Diabetic Vascular Complications 
  He Z., Ma RC. and King GL.Editors: Steven P. Marso and David M. Stern.Lippincott Williams & WilkinsEdition 1st,2004
• International Textbook of Diabetes Mellitus 
  Chapter: Pathogenesis of Diabetic Microvascular Complications 
  Page 1135 - 1159He Z., Rask-Madesen C. and King GL.Editors: R.A. De Fronzo, Ele Ferrannini, Harry Keen and Paul Zimmet.John Wiley & SonsEdition 3rd,2004
• Joslin's Diabetes Mellitus 
  Chapter: Hyperglycemia and Diabetic Microvascular Complications 
  Page 823 - 837Rask-Madsen C., He Z. and King GL.Editors: C. Ronald Kahn.Lippincott Williams & WilkinsEdition 14th,2004
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Abstracts/Posters

• Thyroid Uptake to Urinary Iodine/Creatinine Ratio May be a Predictor of Disease Outcomes for Differentiated Thyroid Cancer (DTC)
  He ZH, Bansal V, & Hennessey JV, ICE/ENDO Endocrine Society Annual Conference, Chicago, 6/22/2014
• Protective Effects of Gender and HDL on Cardiovascular Disease (CVD) In Patients with 50 or More Years of Type 1 Diabetes
  He Z., Keenan HA., Sun JK, Turek SJ., Hastings SM., & King GL., Diabetes, 1/1/2013
• Effect of Incidental Ingestion of Massive Dose of Liothyronine Sodium due to a Compounding Pharmacy Error
  He Z. & Hennessey JV., New England-AACE 4th Annual Meeting, Dedham, MA, 10/27/2012

Lectures

• Differential Factors for Diabetic Nephropathy and Retinopathy 
  Boston, MA - 6/16/2014
• Elimination of Disparity of Diabetes Care in an Asian American-Tailored Program in a Tertiary Care Diabetes Center 
  Boston, MA - 6/16/2014
• Physical Activity Raises HDLc and Protects from CVD in Male Medalists 
  Boston, MA - 6/15/2014