ZacharySimmonsMD

PubMed

• Caring for people living with ALS in Korea: challenges and possible paths forward.
  Crystal Jing Jing Yeo, Zachary Simmons
  Muscle & Nerve. 2024-11-01
• Self-perceived quality of life, cognitive and behavioural impairment in amyotrophic lateral sclerosis.
  Ratko Radakovic, Amy Carroll, Alair Altiero, Carrie Reichwein, Susan Walsh
  Journal of Neurology. 2024-10-01
• A nurse coaching intervention to improve support to individuals living with ALS.
  Susan Walsh, Zachary Simmons, Sheridan Miyamoto, Andrew Geronimo
  Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 2024-09-11

Journal Articles

• Acceptance of brain-computer interfaces in amyotrophic lateral sclerosis  
  Geronimo A, Stephens HE, Schiff SJ, Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2015
• Relationship of creatine kinase to body composition, disease state, and longevity in ALS  
  Gibson SB, Kasarskis EJ, Hu N, Pulst SF, Mendiondo MS, Matthews DE, Mitsumoto H, Tandan R, Simmons Z., Kryscio RJ, Bromberg MB, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2015
• Multidisciplinary ALS clinics in the USA: a comparison of those who attend and those who do not  
  Stephens HE, Felgoise S, Young J, Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2015
• Pain in amyotrophic lateral sclerosis: patient and physician perspectives and practices  
  Stephens HE, Lehman E, Raheja D, Yang C, Walsh S, McArthur DB, Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2015
• Optimizing the clinical examination of the tongue  
  Bandyopadhyay S, Simmons Z, J Clin Neuromuscul Disord, 1/1/2015
• Isaacs syndrome: a review  
  Ahmed A, Simmons Z, Muscle Nerve, 1/1/2015
• The potential of psychological interventions to improve quality of life and mood in muscle disorders  
  Graham CD, Simmons Z, Stuart SR, Rose MR, Muscle Nerve, 1/1/2015
• Patient-perceived outcomes and quality of life in ALS  
  Simmons, Z, Neurotherapeutics, 1/1/2015
• Estimating daily energy expenditure in individuals with amyotrophic lateral sclerosis  
  Kasarskis EJ, Mendiondo MS, Matthews DE, Mitsumoto H, Tandan R, Simmons Z, Bromberg MB, Kryscio RJ for the ALS Nutrition/NIPPV Study Group, Am J Clin Nutr, 1/1/2014
• Loss and wellbeing in ALS: a different perspective on the challenge  
  Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• H63D HFE genotype accelerates disease progression in animal models of amyotrophic lateral sclerosis  
  Nandar W, Neely EB, Simmons Z, Connor JR, Biochim Biophys Acta, 1/1/2014
• Genetic Heterogeneity of ALS: Implications for clinical practice and research  
  Su X, Broach J, Connor JR, Gerhard G, Simmons Z, Muscle Nerve, 1/1/2014
• Pseudobulbar affect: prevalence and management  
  Ahmed A, Simmons Z, Clin Ther Risk Manag, 1/1/2013
• Frontotemporal degeneration in the patient with ALS: helping the caregiver cope  
  Houseman G, Walsh S, Brothers A, Lyter J, Simmons Z, Klapper J, J Neurosci Nurs, 1/1/2013
• Biomarker-based predictive models for prognosis in amyotrophic lateral sclerosis  
  Su XW, Simmons Z, Mitchell RM, Kong L, Stephens HE, Connor JR, JAMA Neurology, 1/1/2013
• H63D HFE polymorphisms are associated with increased disease duration and decreased muscle SOD1 expression in amyotrophic lateral sclerosis patients  
  Su XW, Lee SY, Mitchell RM, Stephens HE, Simmons Z, Connor JR, Muscle Nerve, 1/1/2013
• VALUES: a national multicenter study demonstrating gender differences in amyotrophic lateral sclerosis with behavioral impairment  
  Flaherty C, Brothers A, Hoffer D, Harrison M, Yang C, Legro RS, Simmons Z, Neurodegen Dis Manage, 1/1/2013
• Electrodiagnosis of brachial plexopathies and proximal upper extremity neuropathies  
  Simmons Z, Phys Med Rehab Clin N Am, 1/1/2013
• Amyotrophic lateral sclerosis: time for research about psychological intervention?  
  Pagnini F, Simmons Z, Corbo M, Molinari E, Amyotroph Lateral Scler, 1/1/2012
• Noninvasive ventilation and gastrostomy may not impact overall quality of life in patients with ALS  
  Zamietra K, Lehman EB, Felgoise SH, Walsh SM, Stephens HE, Simmons, Z, Amyotroph Lateral Scler, 1/1/2012
• Quality of life and measures of quality of life in patients with neuromuscular disorders  
  Burns TM, Graham CD, Rose MR, Simmons Z, Muscle Nerve, 1/1/2012
• VALUES: A national multicenter study of regional and gender differences in the FTD prodrome in ALS  
  Flaherty-Craig C, Brothers A, McFalls A, Yang C, Simmons Z, Neurodegen Dis Manage, 1/1/2012
• Psychological health in patients with ALS is maintained as physical function declines  
  Cupp J, Simmons Z, Berg A, Felgoise SH, Walsh SM, Stephens HE, Amyotroph Lateral Scler, 1/1/2011
• Advance care planning for patients with ALS: Feasibility of an interactive computer program  
  Hossler C, Levi BH, Simmons Z, Green MJ, Amyotroph Lateral Scler, 1/1/2011
• Declines in problem solving and anosognosia in ALS: application of Guilford's structure of intellect theory  
  Flaherty-Craig CV, Brothers A, Yang C, Svoboda R, Simmons, Z, Cog Behav Neurol, 1/1/2011
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Books/Book Chapters

• Motor Neuron Disease in Adults. 
  Chapter: Frontotemporal dysfunction and dementia in amyotrophic lateral sclerosis. 
  Page 27 - 41Elman L, Simmons ZEditors: Bromberg M.Oxford University Press USA, New York, NY2015
• Neurorehabilitation. Handbook of Clinical Neurology 
  Chapter: Rehabilitation of Motor Neuron Disease. 
  Page 483 - 498Simmons, ZEditors: Barnes M, Good D, (Michael Aminoff, series ed).Elsevier, Amsterdam, The Netherlands2013
• Neuromuscular Disorders: Management and Therapy. 
  Chapter: Management and Treatment of Autoimmune Neuropathies. 
  Page 215 - 235Simmons, ZEditors: Bertorini T.Saunders/Elsevier, Philadelphia, PA2011
• Neurobiology of Disease. 
  Chapter: Amyotrophic lateral sclerosis-like syndromes associated with malignancy. 
  Page 513 - 519Simmons, ZEditors: Gilman S.Elsevier, Amsterdam, The Netherlands2007
• Handbook of Peripheral Neuropathy. 
  Chapter: Chronic inflammatory demyelinating polyradiculoneuropathy. 
  Page 127 - 159Simmons ZEditors: Bromberg MB, Smith AG.Taylor & Francis, Boca Raton, FL2005
• The Evidence Base for Diabetes Care. 
  Chapter: Treatment of diabetic neuropathy. 
  Page 555 - 576Simmons Z, Feldman ELEditors: Williams R, Wareham N, Kinmonth AL, Herman WH.John Wiley & Sons, West Sussex, England2002
• Neuromuscular Disorders in Clinical Practice. 
  Chapter: Chronic inflammatory demyelinating polyradiculoneuropathy and related disorders. 
  Page 567 - 588Simmons Z, Albers JWEditors: Katirji B, Kaminski H, Preston DC, Ruff RL, Shapiro BE.Butterworth-Heinemann, Boston, MA2002
• Clinical Chemistry: Laboratory Management and Clinical Correlations. 
  Chapter: Cerebrospinal fluid. 
  Page 877 - 891Boyer PJ, Simmons Z, Nifong TPEditors: Lewandrowski K.Lippincott Williams & Wilkins, New York, NY2002
• Hospital Physician Board Review Manual. 
  Chapter: Case studies in peripheral neuropathy. 
  Page 1 - 13Simmons ZEditors: Reichwein RK, Kothari MJ.Turner White Communications, Wayne, PA2000
• Current Therapy in Neurologic Disease. 
  Chapter: Chronic inflammatory demyelinating polyradiculoneuropathy. 
  Page 349 - 353Feldman EL, Simmons ZEditors: Johnson RJ, Griffin JW.Mosby-Year Book, St. Louis, MOEdition 4th,1993
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Abstracts/Posters

• A description of pain in amyotrophic lateral sclerosis.
  Stephens H, Walsh S, Raheja D, Simmons Z, Neurology, 1/1/2015
• A phase 4 prospective study in patients with adult Pompe disease treated with alflucosidase alfa.
  Thurberg B, Carlier P, Kissel J, Schoser B, Pestronk A, Barohn R, Goker-Alpan O, Mozaffar T, Pena LDM, Simmons Z, Straub V, Young P, Sahfi R, Bjartmar C, Van Der Ploeg Z, Neurology, 1/1/2015
• A phase 2 study of mexiletine in sporadic amyotrophic lateral sclerosis.
  Weiss M, Simmons Z, Atassi N, Graves M, Parziale N, Salameh J, Quinn C, Brown R, Distad B, Trivedi J, Shefner J, Duleep A, Barohn R, Dimachkie MMcVey A, Pestronk A, Sw..., Neurology, 1/1/2015
• A surprising case of acute motor neuropathy.
  Zhivotenko V, Bandyopadhyay S, Simmons Z, IXth Annual Meeting of the Pennsylvania Neurological Society, Pittsburgh, PA, 1/14/2014
• Personalized brain-computer interfaces as communication tools in ALS.
  Geronimo A, Schiff SJ, Simmons Z, Neuroscience; Annual meeting of the Society for Neuroscience, Washington, DC, 1/1/2014
• H63D HFE modifies disease pathophysiology in animal models of amyotrophic lateral sclerosis.
  Nandar W, Neely E, Simmons Z, Connor, JR, Neuroscience; Annual meeting of the Society for Neuroscience, Washington, DC, 1/1/2014
• Liposome-encapsulated H-ferritin improves survival in a SOD1 mutant mouse model of amyotrophic lateral sclerosis.
  Snyder AM, Madhankumar AB, Neely EB, Rizk E, Hess OM, Simmons Z, Connor JR, Neuroscience; Annual meeting of the Society for Neuroscience, Washington, DC, 1/1/2014
• Statins and HFE polymorphism adversely impact the SOD1 G93A ALS mouse model.
  Su XW, Nandar W, Neely EB, Simmons Z, Connor JR, Neuroscience; Annual meeting of the Society for Neuroscience, Washington, DC, 1/1/2014
• Gender differences in emerging behavioral change in ALS suggest a neuroendocrine model for treatment.
  Flaherty C, Brothers A, Vankampen D, Sadeghi A, Yang C, Legro R, Manni A, Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• Progression over time of gender differences in emerging ALS cognitive decline from the temporal to frontotemporal regions.
  Flaherty C, Brothers A, Vankampen D, Sadeghi A, Yang C, Legro R, Manni A, Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• H63D modifies disease pathophysiology in an ALs mouse model.
  Nandar W, Neely E, Simmons Z, Connor J, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• Cognitive change and quality of life in amyotrophic lateral sclerosis.
  Niven E, Newton J, Bak T, Stephens H, Simmons Z, Abrahams S, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• Diaphragm pacing referral pathway and outcomes in an academic multidisciplinary ALS clinic.
  Raheja D, Walsh S, Stephens H, Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• A description of physician pain management practice in ALS.
  Simmons Z, Walsh S, Stephens H, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• Liposome-encapsulated H-ferritin improves survival in an SOD1 mutant mouse model of ALS.
  Snyder AM, Madhankumar AB, Neely EB, Rizk E, Hess OM, Simmons Z, Connor J, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• A description of pain in ALS.
  Stephens H, Walsh S, Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• Pain assessments vary in a multinational sample.
  Stephens H, Walsh S, Simmons, Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• HMG-C oA reductase inhibitors and HFE polymorphism accelerate disease progression and shorten survival in the SOD1 G93A ALS mouse model.
  Su X, Nandar W, Neely E, Simmons Z, Connor J, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• Patient communication and treatment preferences in an ALS clinic.
  Walsh S, Stephens H, Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• An assessment of pain reports in ALS using three large data sets.
  Stephens, H, Felgoise S, Walsh S, Simmons Z, Neurology, 1/1/2014
• Phase 2 selection otrial of high-dosage creatine (cre) and two dosages of tamoxifen (tam) in amyotrophic lateral sclerosis.
  Atassi N, Macklin E, Jackson K, Berkley J, Simpson E, Yu H, Walker J, Simmons Z, David W, Barkhaus P, Simionescu L, Dimachkie M, Pestronk A, Salameh J, Weiss M, Bravve..., Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2013
• The relationship between bulbar function and quality of life in patients with ALS.
  Davies J, Stephens H, Simmons, Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2013
• VALUES: a national multicenter study evidencing gender differences in the behavioral variant of frontotemporal lobar degeneration in amyotrophic lateral sclerosis.
  Flaherty C, Brothers A, Hoffer D, Harrison M, Yang C, Legro R, Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2013
• An evaluation of newly diagnosed patient needs: lessons learned from patients and families.
  Klapper J, Walsh S, Schwartz S, Hill S, Simmons Z, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2013
• H63D HFE shortens survival and accelerates disease progression in an ALS mouse model.
  Nandar W, Neely E, Simmons Z, Connor J, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2013
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Lectures

• Ethical Concerns in ALS: Merging Science and Compassion 
  Savannah, GA - 1/30/2015
• ALS: Multidisciplinary Care and Ethical Aspects of Disclosing Bad News and Physician-Assisted Suicide 
  Phila College of Osteopathic Medicine, Philadelphia, PA - 1/28/2015
• Right to Try 
  Chicago, IL - 1/27/2015
• ALS Research Update 
  Hershey, PA - 1/24/2015
• Penn State Hershey ALS Center 
  Hershey, PA - 1/21/2015
• Physician Assisted Suicide: Introduction and Overview 
  Washington, DC - 1/20/2015
• Introduction to Palliative Care 
  Savannah, GA - 1/31/2014
• Psychological Assessment and Management of Patient and Caregiver 
  Savannah, GA - 1/31/2014
• Sacral Plexopathies and Sciatic Neuropathies 
  Savannah, GA - 1/29/2014
• Amyotrophic Lateral Sclerosis: An Overview 
  Hershey, PA - 1/28/2014
• ALS (Lou Gehrig’s Disease): New Approaches to an Old Disease 
  Naples, FL - 1/28/2014
• Altered States of Consciousness 
  Penn State Hershey Medical Center, Hershey, PA - 1/28/2014
• Can Unconsciousness Patients Communicate? 
  Penn State Hershey Medical Center, Hershey, PA - 1/27/2014
• Late Responses 
  Penn State Hershey Medical Center, Hershey, PA - 1/17/2014
• Nerve Conduction Studies: The Basics 
  Penn State Hershey Medical Center, Hershey, PA - 1/16/2014
• Tibial and Sural Nerves 
  Penn State Hershey Medical Center, Hershey, PA - 1/16/2014
• Ethical Issues in End-of-Life Care 
  Penn State University, Hershey, PA - 1/12/2014
• Neuromuscular Research: ALS 
  Penn State University, Hershey, PA - 1/22/2013
• Motor Neuron Disease and its Mimics 
  San Antonio, TX - 1/19/2013
• Brachial Plexopathies 
  San Antonio, TX - 1/18/2013
• Neuromuscular Diseases: A Guide for Pulmonologists 
  Penn State Hershey Medical Center, Hershey, PA - 1/17/2013
• Quality of Life and Coping with Chronic Medical Illness 
  Philadelphia College of Osteopathic Medicine, Philadelphia, PA - 1/8/2013
• ALS (Lou Gehrig’s Disease): No Cure Yet, But Plenty of Hope 
  Penn State Hershey Medical Center. Hershey, PA - 1/20/2012
• Quality of Life in ALS: Assessing and Supporting Caregivers 
  Helen Hayes Hospital, West Haverstraw, NY - 1/9/2012
• Quality of Life in ALS: What Does it Mean? 
  Wadsworth Center, Albany, NY - 1/8/2012
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Other

• Polio and infectious diseases of the anterior horn 
  Simmons Z
  http://www.uptodate.com/contents/polio-and-infectious-diseases-of-the-anterior-horn
  UpToDate, Wolters Kluwer Health - 2012-06-07
• Painless Arm Weakness in a 55-Year-Old Woman. (Original Case for Problem-based learning.) 
  Simmons Z with Stacey L. Clardy, PhD, Neural & Behavioral Science Block
• Polio and infectious diseases of the anterior horn. 
  Simmons, Z
  www.uptodate.com