YogenthiranSaunthararajahMD

PubMed

• 15 citations
  Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons
  Angela Rivers, Kestis Vaitkus, Ramasamy Jagadeeswaran, Maria Armila Ruiz, Vinzon Ibanez
  Experimental Hematology. 2018-11-01
• 14 citations
  Targeting sickle cell disease root-cause pathophysiology with small molecules
  Yogen Saunthararajah
  Haematologica. 2019-09-01
• 200 citations
  Somatic SETBP1 mutations in myeloid malignancies
  Hideki Makishima, Kenichi Yoshida, Nhu Nguyen, Bartlomiej P Przychodzen, Masashi Sanada
  Nature Genetics. 2013-08-01

Abstracts/Posters

• CUL1: Novel Therapeutic Target in Myeloid Neoplasms Harboring -7/Del(7q)
  Yogenthiran Saunthararajah, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• A Single Arm, Phase II Study of Eltrombopag to Enhance Platelet Count Recovery in Older Patients with Acute Myeloid Leukemia (AML) Undergoing Remission Induction Therapy
  Yogenthiran Saunthararajah, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Extended Experience with a Very Low Dose, Metronomic, Subcutaneous Decitabine Regimen Intended to Deplete DNMT1 without Cytotoxicity
  Yogenthiran Saunthararajah, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Integrated Analysis of Copy-Number Alterations and Gene Mutations in 2,000 Patients with Myeloid Neoplasms
  Yogenthiran Saunthararajah, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Large Granular Lymphocytic Leukemia Coexists with Clonal Hematopoiesis of Indeterminate PotentialClinically Relevant Abstract
  Yogenthiran Saunthararajah, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Feedback Responses of the Pyrimidine Metabolism Network Mediate Resistance to Decitabine and 5-Azacytidine
  Yogenthiran Saunthararajah, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• FA Gene Carrier Status Predisposes to Myeloid Neoplasms and Bone Marrow Failure in AdultsClinically Relevant Abstract
  Yogenthiran Saunthararajah, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Iron Catalyzed Hydrogen Sulfide and Its Prevalence during Oxidative Events in Sickle Cell Disease
  Yogenthiran Saunthararajah, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Eltrombopag Creates a Transient Chemical Phenocopy of TET2 Loss of Function That Contributes to Hematopoietic Precursor ExpansionClinically Relevant Abstract
  Yogenthiran Saunthararajah, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
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Lectures

• A First-in-Class Inhibitor of ISWI-Mediated (ATP-Dependent) Transcription Repression Releases Terminal-Differentiation in AML Cells While Sparing Normal Hematopoiesis 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• The LSD1 Inhibitor RN-1 Increases I-Globin . Expression in Baboons By Targeting an Early Event Responsible for I-Globin Repression 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Ultimate Precision: Targeting Cancer but Not Normal Self-Replication 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/4/2018