Wing-KinSynMDPhD, FEBGH, FACP, FRCPE, FRCP

Gastroenterology • Saint Louis, MO

Hepatology & Liver Transplantation

James F King Chair in Gastroenterology / Director, Division of Gastroenterology and Hepatology / Co-Director, Saint Louis University Liver Center / Co-Executive Director, Metabolic & Nutrition Institute / Professor of Medicine / Research Track Fellowship Director / Physician-Scientist / Attending Physician

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Office
1008 South Spring Avenue
SLUCare Academic Pavilion, 2nd Floor
Saint Louis, MO 63110
Phone+1 314-977-2171

Education & Training

University of Sheffield School of MedicineClass of 1998

Certifications & Licensure

MO State Medical License 2021 - 2024
SC State Medical License 2015 - 2022

Clinical Trials

Phase 3 Study to Evaluate the Efficacy and Safety of Elafibranor Versus Placebo in Patients With Nonalcoholic Steatohepatitis (NASH) Start of enrollment: 2016 Mar 01
Terminated
Phase 3
Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension Start of enrollment: 2016 Oct 17
Completed
Phase 2
Study Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis Start of enrollment: 2017 Aug 30
Completed
Phase 3

Publications & Presentations

PubMed

61 citations
Human intrahepatic regulatory T cells are functional, require IL‐2 from effector cells for survival, and are susceptible to Fas ligand‐mediated apoptosis
Yung-Yi Chen, Hannah C. Jeffery, Stuart Hunter, Ricky H. Bhogal, Jane Birtwistle
Hepatology. 2016-07-01
122 citations
Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer.
George Philips, Isaac S. Chan, Marzena Swiderska, Vanessa T. Schroder, Cynthia D. Guy
Plos One. 2011-09-02
284 citations
Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans
Alessia Omenetti, Alessandro Porrello, Youngmi Jung, Liu Yang, Yury Popov
The Journal of Clinical Investigation. 2008-10-01

Committees

NASH Council Member, Global Liver Institute 2018 - Present
Committee Member, National VA NAFLD Strategic Planning Committee 2019 - 2021
Education Steering Committee, AASLD Liver Fibrosis SIG 2018 - 2020
Member, RHJ VAMC R&D Committee 2016 - 2021