WillisCrockerMaddreyMD

Gastroenterology • Dallas, TX

Hepatology & Liver Transplantation

Professor, Internal Medicine, University of Texas Southwestern Medical Center, Southwestern Medical School

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Office
5323 Harry Hines Blvd
Dallas, TX 75390
Phone+1 214-645-0624

Fax+1 214-645-0078

Education & Training

Johns Hopkins UniversityResidency, Internal Medicine, 1968 - 1970
Johns Hopkins UniversityResidency, Internal Medicine, 1964 - 1966
Johns Hopkins University School of MedicineClass of 1964
Wake Forest UniversityB.S., Summa Cum Laude, 1956 - 1960

Certifications & Licensure

TX State Medical License 1991 - 2025
PA State Medical License 1982 - 2006
MD State Medical License 1970 - 1991
American Board of Internal Medicine Internal Medicine

Awards, Honors, & Recognition

Henry Strong Denison Scholar in the Medical Sciences
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012
Distinguished Alumnus Award The Johns Hopkins University School of Medicine, 2009
Fellow (AGAF) American Gastroenterological Association, 2006
Distinguished Service Award American Association for the Study of Liver Diseases, 2000
Distinguished Educator Award American Gastroenterological Association, 1998
Adelyn and Edmund M. Hoffman Distinguished Chair in Medical Science The University of Texas Southwestern Medical Center, 1998
The Johns Hopkins Society of Scholars The Johns Hopkins University, 1994
Honorary Medical College of Ohio, 1994
Distinguished Service Citation Wake Forest University, 1991
Christian R. and Mary F. Lindback Award for Distinguished Teaching in the Clinical Sciences Jefferson Medical College, 1986
Elected Member The American Society for Clinical Investigation, 1981
George Stuart Outstanding Teacher Award The Johns Hopkins University School of Medicine, 1970
Super Doctor SuperDoctors.com
Whos Who in Medicine and Healthcare Marquis Whos Who
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Publications & Presentations

PubMed

4 citations
Final results from the ribavirin pregnancy registry, 2004-2020.
Susan M Sinclair, Judith K Jones, Richard K Miller, Michael F Greene, Paul Y Kwo
Birth Defects Research. 2022-12-01
4 citations
Changing Times in Liver Transplantation for Alcohol-Associated Liver Disease
Mack C. Mitchell, Willis C. Maddrey
JAMA Internal Medicine. 2019-03-01
140 citations
Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo—a Meta-analysis of Individual...
Alexandre Louvet, Mark Thursz, Dong Joon Kim, Julien Labreuche, Stephen R. Atkinson
Gastroenterology. 2018-08-01

Journal Articles

Efficacy, safety and clinical pharmacology of macitentan in comparison to other endothelin receptor antagonists in the treatment of pulmonary arterial hypertension
Dingemanse J1, Sidharta PN, Maddrey WC, Rubin LJ, Mickail H, Expert Opinion On Drug Safety, 1/1/2014
Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis: meta-analysis of individual patient data
CL., Ramond MJ., Naveau S., Maddrey WC., Morgan TRMathurin P., O’Grady J., Carithers RL.,Phillips M., Louvet A., Mendenhall, Gut, 1/1/2011
Evaluation of Drug-Induced Serious Hepatotoxicity (eDISH) Application of this Data Organization Approach to Phase III Clinical Trials of Rivaroxaban after Total Hip or...
Watkins, P.B., M. Desai, S. D. Berkowitz, G. Peters, Y. Horsmans, D. Larrey, and W. Maddrey, Drug Safety, 1/1/2011
The Ribavirin Pregnancy Registry: Findings after 5 Years of Enrollment, 2003-2009
Roberts, S.S., Miller, R.K., Jones, J.K., Lindsay, K.L., Greene, M.F., Maddrey, W.C., Williams, I.T., Liu J., Spiegel, R.J, Birth Defects Research (Part A): Clinical and Molecular Teratology, 1/1/2010
Hepatitis B Virus Infection in 6,130 Unvaccinated Korean-American Surveyed Between 1988 and 1990
Hann, H.L., Hann, R.S., Maddrey, W.C., American Journal of Gastroenterology, 1/1/2007
Drug-Induced Hepatotoxicity
Maddrey, W.C., Clinical Gastroenterology, 1/1/2005
Role of antibiotics in the management of hepatic Role of antibiotics in the management of hepatic
Maddrey, W.C., Reviews in Gastroenterological Disorders, 1/1/2005
Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis (AH): individual data analysis of the last three randomized placebo hepatitis (...
Mathurin, P., Mendenhall, C.L., Carithers, R.L., Raymond, M.J., Maddrey, Mathurin, P., Mendenhall, C.L., Carithers, R.L., Raymond, M.J., Maddrey, Journal of Hepatology, 1/1/2002
Update in hepatology
Maddrey, W.C., Annals of Internal Medicine, 1/1/2001
Hepatitis B – An important public health issue
Maddrey, W.C., Clin Lab, 1/1/2001
Adult hepatitis B vaccination using a novel triple antigen recombinant vaccine
Young, M.D., Schneider, D.L., Zuckerman, A.J., Du, Wei., Dickson, B., Maddrey, W.C., Hepatology, 1/1/2001
Comparison of a triple antigen and a single antigen recombinant vaccine for adult hepatitis B vaccination
Young, M.D., Gooch, W.M. III., Zuckerman, A.J., Du, W., Dickson, B., Maddrey, W.C., Journal of Medical Virology, 1/1/2001
A multi-center controlled study of rapid hepatitis B vaccination using a novel triple antigen recombinant vaccine
Young, M.D., Rosenthal M.H., Dickson, B., Du W., Maddrey, W.C., Vaccine, 1/1/2001
Alcohol-induced liver disease
Maddrey, W.C., Clinics in Liver Disease, 1/1/2000
A model for a managed care approach to increase hepatitis awareness: Part I
Schiff, E.R., Maddrey W.C., Keeffe, E.B., Managed Care Interface, 1/1/2000
A model for a managed care education approach to increase hepatitis awareness: Part II
Schiff, E.R., Maddrey, W.C., Keeffe, E.B., Managed Care Interface, 1/1/2000
The hepatic safety and tolerability of the novel cyclooxygenase-2 inhibitor celecoxib
Maddrey, W.C., Maurath, C.J., Verburg, K.M. Geis, G.S, American Journal of Therapeutics, 1/1/2000
Bioartificial liver in the treatment of hepatic failure
Maddrey, W.C., Liver Transplantation, 1/1/2000
Hepatitis B: an important public health issue
Maddrey, W.C., Journal of Medical Virology, 1/1/2000
Proceedings of the international symposium on treatment of chronic hepatitis B infection with lamivudine, an oral antiviral drug
Maddrey, W.C., Journal of Medical Virology, 1/1/2000
Biliary bile acids in primary biliary cirrhosis: Effect of ursodeoxycholic acid
Combes, B., Carithers Jr, R.L., Maddrey, W.C., Munoz, S., Garcia-Tsao, G., Bonner, GF., Boyer J.L., Luketic, V.A., Schiffman, M.L., Peters, M.G., White, H., Zetterman,..., Hepatology, 1/1/1999
The effect of ursodeoxycholic acid on the florid duct lesion of primary biliary cirrhosis
Combes, B., Markin, R.S., Wheeler D.E., Rubin, R., West, A.B., Mills, A.S., Eigenbrodt, E.H., Maddrey, W.C., Munoz, S.J., Garcia-Tsao, G., Bonner, G.F., Boyer, J.L., L..., Hepatology, 1/1/1999
EASL International Consensus Conference on Hepatitis C – Paris, 26-27, February 1999 – Consensus statement
Marcellin, P., Alberti, A., Dusheiko, G., Esteban, R., Manns, M., Shouval, D., Weiland, O., Williams, R., Benhamou, J.P., Rhodes, J., Alter, H., Bismuth, H., Desmet, V..., Journal of Hepatology, 1/1/1999
International Autoimmune Hepatitis Group Report: Review of criteria for diagnosis of autoimmune hepatitis
Alvarez, F., Berg, P.A., Bianchi, F.B., Bianchi, L., Burroughs, A.K., Cancado, E.L., Chapman, R.W., Cooksley, W.G., Czaja, A.J., Desmet, V.J., Donaldson, P.T., Eddlest..., Journal of Hepatology, 1/1/1999
Safety of combination interferon alfa-2b/ribavirin therapy in chronic hepatitis C-relapsed and treatment-naïve patients
Maddrey, W.C., Seminars in Liver Disease, 1/1/1999
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Books/Book Chapters

Schiff’s Diseases of the Liver
Schiff, E.R., Sorrell, M.F., Maddrey, W.CWiley-Blackwell (John Wiley & Sons, Ltd.)2012
CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy
Chapter: Drug-Induced Liver Disease
Maddrey, W.C.Editors: Norton J. Greenberger.The McGraw-Hill Companies, Inc.2009
Schiff’s Diseases of the Liver
Chapter: Overview: Alcohol and Drug-Induced Diseases
Page 875 - 880Maddrey, W.C.Editors: E.R. Schiff, M.S. Sorrell and W.C. Maddrey.Lippincott Williams & Wilkins2007
Schiff’s Diseases of the Liver
Schiff, E.R., Sorrell, M.F., Maddrey, W.C.Lippincott Williams & WilkinsEdition 10th,2007
Atlas of the Liver
Maddrey, W.C.Current MedicineEdition 4th,2006
Atlas of the Liver
Maddrey, W.C.Current MedicineEdition 3rd,2004
Schiff’s Diseases of the Liver
Schiff, E.R., Sorrell, M.F., Maddrey, W.CLippincott Williams & Wilkins2002
Drug-Induced Liver Disease
Chapter: Clinicopathologic Patterns of Drug-Induced Liver Disease
Maddrey, W.C.Editors: Neil Kaplowitz and Laurie DeLeve.Marcel Dekker, Inc.2002
Transplantation of the Liver
Maddrey, W.C. Schiff, E.R., Sorrell, M.F.Lippincott Williams & WilkinsEdition 3rd,2001
Atlas of the Liver
Maddrey, W.C.Current MedicineEdition 2nd,2000
Schiff’s Diseases of the Liver
Chapter: Granulomas of the Liver
Page 1571 - 1585Maddrey, W.C.Editors: Granulomas of the Liver.Lippincott-Raven1999
Schiff’s Diseases of the Liver
Chapter: Overview: The Cholestasis Disorders
Page 607 - 610Maddrey, W.C.Editors: Schiff, M.S. Sorrell and W.C. Maddrey.Lippincott-Raven1999
Schiff’s Diseases of the Liver
Chapter: Overview: Alcohol and Drug-Induced Diseases
Page 937 - 940Maddrey, W.C.Editors: E.R. Schiff, M.S. Sorrell and W.C. Maddrey.Lippincott-Raven1999
Schiff’s Diseases of the Liver
Schiff, E.R., Sorrell, M.F., Maddrey, W.C.Lippincott-RavenEdition 8th,1999
The Liver, Vol I, Gastroenterology and Hepatology: The Comprehensive Visual Reference
Maddrey, W.C.Editors: M. Feldman.Current Medicine1996
Transplantation of the Liver
Maddrey, W.C., Sorrell, M.FAppleton & LangEdition 2nd,1995
Alcoholic Liver Disease: Pathology and Pathogenesis
Chapter: Introduction. Alcohol and the liver: An Overview
Page 3 - 13Maddrey, W.C.Editors: P. Hall.Edward Arnold, London, UK1995
Drug-Induced Liver Disease
Chapter: Foreward
Maddrey, W.C.Editors: G.C. Farrell.Churchill Livingston, Edinburg, TX1994
Bile Acids and the Hepatobiliary System
Chapter: A randomized, double-blind, placebo-controlled trial of ursodeoxychlic acid in primary biliary cirrhosis
Page 289 - 291Combes, B., Carithers, R.L., Maddrey, W.C., Munoz, S.J., McDonald, M.F., Garcia-Tsao, G., Boyer, J.L., Luketic V., Shiffman, M.L., Peters, M.G., White, H., Zetterman, ...Kluwer Academic Publishers1992
Complications of Liver Disease
Chapter: Transplantation of the liver
Page 339 - 369Munoz, S.J., Maddrey, W.C.Mosby Year Book1992
Surgery of the Alimentary Tract
Chapter: Laboratory investigation of liver disease
Page 287 - 291Maddrey, W.C.Editors: G.D. Zuidema.Saunders, Philadelphia, PA1991
Shackleford's, Surgery of the Alimentary Tract
Chapter: Percutaneous needle biopsy of the liver
Page 292 - 295Maddrey, W.C.Editors: G.D. Zuidema.Saunders, Philadelphia, PA1991
Autoimmune Liver Diseases
Chapter: Drug-induced chronic active hepatitis
Page 219 - 232Maddrey, W.C.Editors: Edward L. Krawitt & Russell H. Wiesner.Raven Press, Ltd, New York, NY1991
Progress in Liver Diseases
Chapter: Bone disease in patients with primary biliary cirrhosis
Page 537 - 554Maddrey, W.C.Editors: H. Popper and F. Schaffner.Grune & Stratton, Inc.1990
Effects of Branched Chain Amino Acids and Ketoanalogues on Brain Branched Chain and Aromatic Amino Acids in Experimental Liver Disease
Page 861 - 866Munoz, S., Stafford, M., Westerberg, S., Walser, M., Maddrey, WEditors: Dr. Gert Lubec.ESCOM Science Publishers B.V.1990
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Lectures

27th Annual New Treatments in Chronic Liver Disease
Scripps Conference Services & CME /Scripps Translational Science Institute (STSI), San Diego, Califo - 3/31/2012
40th Annual USC Diagnostic & Therapeutic Skills in Internal Medicine
University of Southern California, Maui, Hawaii - 3/12/2012
Liver Transplantation
Australia - 1/1/1990
Perspectives for the 90's
Philadelphia, PA - 1/8/1989
Connections
Philadelphia, PA - 1/9/1988
Philadelphia, PA - 1/4/1987
Medicine: The Art and the Craft
Philadelphia, PA - 1/5/1986
New Realities
Philadelphia, PA - 1/6/1985
Aequanimitas Revisited
Philadelphia, PA - 1/7/1984
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Press Mentions

Liver Transplant Survivor’s Recovery Linked to Sociodemographic Factors, UTSW Study ShowsApril 26th, 2023
UT Southwestern Nephrologist Addresses National Kidney FoundationApril 12th, 2023
The Origins of the Modern‐Day Study of Drug Hepatotoxicity: Focus on Hyman J. ZimmermanMarch 2nd, 2020
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Professional Memberships

American Gastroenterological Association - AGA
Fellow