WilliamNRomMDMPH

PubMed

• 57 citations
  Integrated Metabolomics and Proteomics Highlight Altered Nicotinamide- and Polyamine Pathways in Lung Adenocarcinoma.
  Johannes F. Fahrmann, Dmitry Grapov, Kwanjeera Wanichthanarak, Brian C. DeFelice, Michelle Salemi
  Carcinogenesis. 2017-01-03
• 389 citations
  Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype.
  Leopoldo N. Segal, Jose C. Clemente, Jun Chieh J. Tsay, Sergei B. Koralov, Brian C. Keller
  Nature Microbiology. 2016-04-04
• 82 citations
  HIV infection is associated with reduced pulmonary diffusing capacity
  Kristina Crothers, Kathleen A. McGinnis, Eric C. Kleerup, Cherry Wongtrakool, Guy W. Soo Hoo
  Journal of Acquired Immune Deficiency Syndromes. 2013-11-01

Journal Articles

• Epigenetically Regulated PAX6 Drives Cancer Cells Toward a Stem-like State via GLI-SOX2 Signaling Axis in Lung Adenocarcinoma  
  William N Rom, Harvey I Pass, Zahra Maleki, Nature
• A Gene Expression Classifier from Whole Blood Distinguishes Benign from Malignant Lung Nodules Detected by Low-Dose CT  
  Anil Vachani, William N Rom, Gerard Criner, Harvey Pass, Clinical Cancer Research
• Airway Microbiota Is Associated with up-Regulation of the PI3K Pathway in Lung Cancer  
  Benjamin G Wu, Harvey Pass, William N Rom, Daniel H Sterman, Vivek Murthy, Martin J Blaser, Michael D Weiden, Leopoldo N Segal, ATS Journals
• Integrated metabolomics highlight altered nicotinamide- and polyamine pathways in lung adenocarcinoma  
  Fahrmann JF, Grapov DD, Wanichthanarak K, DeFelice BC, Salemi MR, Rom WN, Gandara DR, Phinney BS, Fiehn O, Pass H, Miyamoto S, Carcinogenesis, 1/1/2017
• Anaerobic bacterial fermentation products increase tuberculosis risk in antiretroviral-drug-treated HIV patients  
  Segal L, Clemente JC, Li Y, Ruan C, Cao J, Danckers M, Morris A, Tapyrik S, Wu BG, Diaz P, Calligaro G, Dawson R, van Zyl-Smit RN, Dheda K, Rom WN, Weiden MD, Cell Host Microbe, 1/1/2017
• A panel of novel detection and prognostic methylated DNA markers in primary non-small cell lung cancer and serum DNA  
  Ooki A, Maleki Z, Tsay Jun-Chieh J, Goparaju CM, Brait M, Turaga N, Nam Hae-Seong, Rom WN, Pass H, Sidransky D, Guerrero-Preston R, Hoque MO, Clinical Cancer Research, 1/1/2017
• Clinical validation of a blood-based classifier for diagnostic evaluation of asymptomatic individuals with pulmonary nodules  
  Birse CE, Tomic JL, Pass HI, Rom WN, Lagier RJ, Clinical Proteomics, 1/1/2017
• Identification of autoantibody to ECH1 and HNRNPA2B1 as potential biomarkers in the early detection of lung cancer  
  Dai L, Li J, Tsay J-C, Yie T-A, Munger JS, Pass H, Rom WN, Tan EM, Zhang J-Y, Oncoimmunology, 1/1/2017
• Extracellular mRNA detected by tethered lipoplex nanoparticle biochip for lung adenocarcinoma detection  
  James LL, Yang Z, Rahman M, Ma J, Kwak KJ, McElroy J, Shilo K, Goparaju C, Yu L, Rom W, Kim TK, Wu X, He Y, Wang K, Pass HI, Nana-Sinkam P, Am J Respir Crit Care Med, 1/1/2016
• Proteomic profiling of lung adenocarcinoma indicates heightened DNA repair, antioxidant mechnaisms and identifies LASP1 as a potential negative predictor of survival  
  Fahrmann J, Grapov D, Phinney B, Stroble C, DeFelice BC, Rom WN, Gandara DR, Zhang Y, Fiehn O, Pass H, Miyamoto S, Clinical Proteomics, 1/1/2016
• Distal airway dysfunction identifies pulmonary inflammation in asymptomatic smokers  
  Berger KI, Pradhan DR, Goldring RM, Oppenheimer BW, Rom WN, Segal LN, ERJ Open Research, 1/1/2016
• Autoantibodies against tumor-associated antigens in the early detection of lung cancer  
  Dai L, Tsay J-C, Li J, Yie T-A, Munger JS, Pass H, Rom WN, Zhang Y, Tan EM, Zhang J-Y., Lung Cancer, 1/1/2016
• Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype  
  Segal LN, Clemente JC, Koralov S, Tsay J-C, Koralov SB, Keller BC, Wu BG, Li Y, Shen N, Ghedin E, Morris A, Diaz P, Huang L, Wikoff WR, Ubeda C, Artacho A, Rom WN, Ste..., Nature Microbiol, 1/1/2016
• Progression from respiratory dysfunction to failure in late-onset Pompe disease  
  Berger KI, Chan Y, Rom WN, Oppenheimer BW, Goldring RM, Neuromuscular Disorders, 1/1/2016
• Factors associated with abnormal spirometry among HIV-infected individuals  
  Drummond MB, Huang L, Diaz P, Kirk G, Kleerup EC, Morris A, Rom W, Weiden MD, Zhao E, Thompson B, Crothers K, AIDS, 1/1/2015
• Environmental Lung Diseases-2015  
  Rom WN and Reibman J, Semin Respir Crit Care Med, 1/1/2015
• Osteopontin velocity differentiates lung cancers from controls in a CT Screening population  
  Joseph S, Harrington R, Walter D, Beck A, Litton T, Hirsch N, Blasberg J, Rom WN, Pass H, Donington J, Cancer Biomarkers, 1/1/2013
• HIV infection is associated with reduced pulmonary diffusing capacity  
  Crothers K, McGinnis K, Kleerup E, Wongtrakool C, Hoo GS, bJ, Sharafkhaneh A, Huang L, Luo Z, Thompson B, Diaz P, Kirk GD, Rom W, Detels R, Kingsley L, Morris A, J Acquir Immune Defic Syndr, 1/1/2013
• Climate change and global public health  
  Pinkerton KE, Rom WN, Carlsten C, Jaakola JJK, Bayram H, Sigsgaard T, Elci MA, Costa DL, Turk Toraks Derg, 1/1/2013
• Impact of a Computer-Aided Detection (CAD) System Integration into a picture archiving and communication system (PACS) on reader sensitivity and efficiency for the det...  
  Bogoni L, Ko JP, Alpert J, Anand V, Fantauzzi J, Florin CH, Koo CW, Mason D, Rom WN, Shiau M, Salganicoff M, Naidich DP, J Digit Imaging, 1/1/2012
• Molecular analysis of plasma DNA for the early detection of lung cancer by quantitative methylation specific PCR  
  Ostrow K, Hoque M, Loyo M, Brait M, Greenberg A, Siegfried J, Grandis J, David AG, Bigbee W, Rom W, Sidransky D, Clin Cancer Research, 1/1/2010
• Wnt pathway in pulmonary fibrosis in the bleomycin mouse model  
  Liu L, Carron B, Yee HT, Yie TA, Hajjou M, and Rom WN, Journal of Environmental Pathology, Toxicology, and Oncology, 1/1/2009
• Molecular origin of leprosy endemic to New York City  
  Keo T, Martiniuk F, Latkowski J, Cabrera A, Rom WN, and Levis WR, Clin Infect Dis, 1/1/2008
• Angiopoietin-1 increases survival and reduces the development of lung edema induced by endotoxin administration in a murine model of acute lung injury  
  Huang YQ, Sauthoff H, Pipiya T, Cheng J, Heitner S, Chen S, Szentirmai O, Carter B, Rom WN, and Hay JG, Crit Care Medicine, 1/1/2008
• Standard operating procedures for serum and plasma collection: early detection research network consensus statement standard operating procedure integration working group  
  Tuck MK, Chan DW, Chia D, Godwin AK, Grizzle WE, Krueger KE, Rom W, Sanda M, Sorbara L, Stass S, Wang W, Brenner DE, J Proteome Res, 1/1/2008
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Books/Book Chapters

• Fishman’s Pulmonary Diseases and Disorders. 
  Chapter: Asbestos-related lung disease. 
  Page 1322 - 1333Rom WNEditors: Grippi MA.McGraw Hill, New York, NY2015
• Global Climate Change and Public Health 
  Chapter: Introduction: Consequences of Global Warming to the Public’s Health. 
  Page 1 - 20Rom WN and Pinkerton KESpringer-Humana Press, New York, NY2013
• Global Climate Change and Public Health 
  Editors: Pinkerton KE and Rom WN.Springer-Humana Press, New York, NY2013
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: Alaska: America’s Wilderness Frontier 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: Chlorofluorocarbons and the Development of the Ozone Hole 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: Climate Change Policy Options 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: Environmental Policy and the Land: Wilderness Preservation 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: Environmental Tobacco Smoke 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: National Green Energy Plan 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: Ozone 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: Particulate Matter 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: Sulfur Dioxide and Acid Rain 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: The Clean Air Act and the National Environmental Policy Act 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: The Clean Water Act and Water Ecosystems 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Environmental Policy and Public Health: Air Pollution, Global Climate Change, and Wilderness. 
  Chapter: Toxic Chemicals in the Environment: Government Regulations and Public Health 
  Rom WNJossey-Bass (Wiley), San Francisco, CA2011
• Occupational and Environmental Lung Diseases 
  Chapter: Traditional urban pollution. 
  Page 405 - 420Parsia S, Patrawalla A, and Rom WNWiley-Blackwell, West Sussex, United Kingdom2010
• Environmental and Occupational Medicine 
  Chapter: The Discipline of Environmental and Occupational Medicine. 
  Page 3 - 8Rom WNEditors: Rom, William N., Editor, and Markowitz, Steven, Associate Editor.Lippincott Williams & Wilkins, Philadelphia, PAEdition 4th,2007
• Environmental and Occupational Medicine 
  Chapter: Asbestosis, Pleural Fibrosis, and Lung Cancer. 
  Page 298 - 316Rom WNEditors: Rom, William N., Editor, and Markowitz, Steven, Associate Editor.Lippincott Williams & Wilkins, Philadelphia, PAEdition 4th,2007
• Environmental and Occupational Medicine 
  Chapter: High-altitude Illnesses. 
  Page 1326 - 1336Rom WNEditors: Rom, William N., Editor, and Markowitz, Steven, Associate Editor.Lippincott Williams & Wilkins, Philadelphia, PAEdition 4th,2007
• Environmental and Occupational Medicine 
  Chapter: Environmental Law and Policy. 
  Page 1619 - 1634Miller JG and Rom, WNEditors: Rom, William N., Editor, and Markowitz, Steven, Associate Editor.Lippincott Williams & Wilkins, Philadelphia, PAEdition 4th,2007
• Environmental and Occupational Medicine 
  Editors: Rom, William N., Editor, and Markowitz, Steven, Associate Editor.Lippincott Williams & Wilkins, Philadelphia, PAEdition 4th,2007
• Molecular Pathology of Lung Diseases. 
  Chapter: Pathogenesis of Pulmonary Fibrosis. Chapter 44, 
  Munger JS and Rom WNSpringer2007
• Medical Mineralogy and Geochemistry 
  Chapter: Interaction of iron and calcium minerals in coals and their roles in coal dust-induced occupational lung diseases. 
  Huang X, Gordon T, Rom WN, and Finkelman RBEditors: Schoonen M, and Niati, N.2006
• Lung Cancer: Principles and Practice. 
  Chapter: Evolving Early Detection Modalities in Lung Cancer Screening. 
  Page 265 - 273Spivack SD and Rom WNLippincott Williams & Wilkins, Philadelphia, PA2005
• Tuberculosis 
  Chapter: Cytokine Response in Tuberculosis. 
  Page 285 - 300Condos R and Rom WNEditors: Rom WN and Garay S.Philadelphia, PA, Philadelphia, PAEdition 2nd,2004
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Abstracts/Posters

• Serum Achaete-Scute Homologue 1 (ascl1) and Forkhead Box P3 (foxp3) concentrations in subjects with benign lung nodules and lung adenocarcinomas.
  Lee MH, Gopisetti N, Yie T-A, Rom WN, Tsay JJ, Am J Respir Crit Care Med, 1/1/2017
• Lung cancer and lung microbiome.
  Tsay JJ, Clemente J, Lhakhang T, Li Y, Yie T-A, Wu BG, Kapoor B, Wang J, Sterman DH, Heguy A, Rom WN, Blaser M, Segal LN, Am J Respir Crit Care Med, 1/1/2017
• Lung microbiome dysbiosis is a risk factor for pulmonary diffusion abnormalities in antiretroviral treated HIV-infection.
  Weiden MD, Segal LN, Clemente J, Li Y, Danckers-Degregory M, Morris AM, Tapyrik S, Diaz P, Dawson R, Van Zyl-Smit R, Dheda KUJ, Rom WN, Am J Respir Crit Care Med, 1/1/2017
• Mixed panel biomarkers for early diagnosis of lung cancer.
  Laboe C, Lee M, Gopisetti N, Yie T –A, Dai L, Zhang J –Y, Rom W, Tsay J -C, Chest, 1/1/2017
• Achaete-Scute Homologue 1 (ASCL1) expression in the contralateral peripheral airways of subjects with lung adenocarcinoma.
  Lee MH, Yie T-A, Tsay JJ, Rom WN, American Thoracic Society Conference, San Francisco, CA, 1/15/2016
• Potential of autoimmune response against tumor-associated antigens to predict risk of developing lung cancer.
  Tsay JJ, Dai L Yie T-A, Munger J, Pass H, Tan E, Zhang J, Rom WN, American Thoracic Society Conference, San Francisco, CA, 1/15/2016
• Progression from respiratory dysfunction to failure in late-onset Pompe Disease.
  Berger KI, Chan Y, Rom WN, Goldring RM, Am J Respir Crit Care Med, 1/1/2016
• Sonic Hedgehog (shh) signaling regulates myofibroblast function duroing alveolar septum formation in postnatal lung.
  Kugler MC, Loomis CA, Ramos J, Joyner AL, Rom WN, Rifkin DB, Munger J, Am J Respir Crit Care Med, 1/1/2016
• Serum short chain fatty acids increase the risk of tuberculosis in HIV patients on antiretroviral therapy and inhibit Th1 and Th17 immune response.
  Weiden MD, Clemente JC, Li Y, Friedman E, Ruan C, Cao J, Pooran A, Davids M, Calligaro G, Dawson R, Van Zyl-Smit RN, Dheda K, Rom WN, Segal L, Am J Respir Crit Care Med, 1/1/2016
• Additive and synergistic effects of LPA in World Trade Center particulate matter-induced inflammation.
  Caraher EJ, Kwon S, Lee AK, Chen L-C, Gordon T, Prezant DJ, Rom WN, Weiden MD, Nolan A, American Thoracic Society Conference, Denver, CO, 1/17/2015
• Inciting RAGE: World Trade Center lung injury and potential therapy with pioglitazone in a murine model.
  Caraher EJ, Kwon S, Lee AK, Echevarria GC, Chen L-C, Gordon T, Prezant DJ, Rom WN, Schmidt AM, Weiden MD, Nolan A, American Thoracic Society Conference, Denver, CO, 1/17/2015
• Lung microbiome enriched in anaerobes with a blunted TLR response.
  Friedman E, Segal LN, Clemente JC, Wikoff WR, Li Y, Rom WN, Fiehn O, Blaser MJ, Weiden MD, American Thoracic Society Conference, Denver, CO, 1/17/2015
• Expression of Sonic Hedgehog pathway genes is different during alveolarization and maturation phase in postnatal lung development.
  Kugler MC, Joyner AL, Loomis CA, Rom WN, Rifkin D, Munger JS, American Thoracic Society Conference, Denver, CO, 1/17/2015
• Biomarkers of World Trade Center lung injury.
  Kwon S, Caraher EJ, Prezant DJ, Rom WN, Weiden MD, Nolan A, American Thoracic Society Conference, Denver, CO, 1/17/2015
• Elevated sputum acrolein-DNA adduct levels in lung cancer patients.
  Tsay JJ, Balbo S, Yie T-A, Converse C, Iles J, Munger JS, Pass H, Hecht S, Rom WN, American Thoracic Society Conference, Denver, CO, 1/17/2015
• Magnitude of autoimmune response in tumor-associated antigens correlates with obstructive impairment and dyspnea in smokers.
  Tsay, JJ, Dai L, Zhang J, Yie T-A, Munger JS, Tan EM, Rom WN, American Thoracic Society Conference, Denver, CO, 1/17/2015
• Evaluation of the microbiome associated with lung cancer.
  Wu B, Cahaney CF, Tsay JJ, Clemente JC, Li Y, Marunchak T, Rom WN, Blaser MJ, Pass HI, Munger JS, Weiden MD, Segal LN, American Thoracic Society Conference, Denver, CO, 1/17/2015
• Significance of emphysema in a lung cancer screening cohort.
  Mukherjee V, Messina J, Tsay JJ, Munger J, Rom, W, Chest, 1/1/2015
• Inciting Rage: World Trade Center lung injury and therapy in a murine model.
  Caraher EJ, Kwon S, Lee AK, Echevarria GC, Chen L-C, Gordon T, Prezant DJ, Rom WN, Schmidt AM, Weiden MD, Nolan A, Clinical & Translational Science, 1/1/2015
• Induction of Achaete-Scute Homologue 1 (ASCL1) by cigarette smoke condensate in A549 Cells.
  Lee MH, Yie T-A, Munger JS, Tsay JJ, Rom WN, J Thoracic Oncol, 1/1/2015
• Anti-Glycan antibody profiling in de-novo stage IV non-small cell lung cancer: A pilot study.
  Seetharamu N, Vuskovic M, Chachoua A; Brusca-Augello G, Barbuti A-M, Thomson JE, Gills I, Preiss J, Joseph S, Ma H, Rom WN, Huflejt ME, Journal Thoracic Oncol, 1/1/2015
• Validation of blood-based biomarker for classification of patients with indeterminate pulmonary nodules.
  Tomic JL, Lagier RL, Pass HI, Rom WN, Pollard TR, Birse CE, Journal Thoracic Oncol, 1/1/2015
• One Airway: Biomarkers of protection from upper and lower airway injury after World Trade Center dust exposure.
  Cho SJ, Echevarria GC, Kwon S, Naveed B, Schenck E, Tsukiji J, Rom WN, Prezant DJ, Nolan A, Weiden MD, American Thoracic Society Conference, San Diego, CA, 1/16/2014
• YKL-40 is a protective biomarker for fatty liver in World Trade Center particulate matter-exposed firefighters.
  Cho SJ, Echevarria GC, Lee YI, Kwon S, Tsukiji J, Rom WN, Prezant Dj, Nolan A, Weiden MD, American Thoracic Society Conference, San Diego, CA, 1/16/2014
• The lower airway microbiome of HIV subjects with and without pneumonia is characterized by enrichment with Psychrobacter and Microbacterium.
  Danckers M, Alekseyenko A, Clemente JC, Rom WN, Blaser MJ, Weiden MD, Segal LN, American Thoracic Society Conference, San Diego, CA, 1/16/2014
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Lectures

• Rafting the Alsek River 
  Explorer’s Club, New York, NY - 1/1/2017
• Keynote: Nuclear Energy, Climate Change, and Public Health. 
  United Nations, NY - 1/26/2016
• Keynote: Climate Change and Public Health 
  UCSF-Fresno, CA - 1/23/2016
• Autoantibodies, Metabolomics, and N-Glycosylation as Biomarkers for the Early Detection of Lung Cancer 
  National Cancer Institute, Atlanta, GA - 1/1/2015
• Global Climate Change and Public Health 
  Alta, UT - 1/1/2015
• Biomarkers for Lung Cancer after Biomass Exposure. 
  Washington, DC - 1/1/2014
• Anti-Glycan Autoantibodies and Early Detection of Lung Cancer 
  Washington, DC - 1/1/2014
• Climate Change and Public Health U.S. 
  Washington, DC - 1/1/2014
• Global TB-HIV and The Environment. 
  Albert Einstein College of Medicine - 1/1/2014
• Global TB/HIV and The Environment. 
  American College of Chest Physicians, Chicago, IL - 1/29/2013
• NYU Lung Cancer Biomarker Center: Biomarkers to Distinguish Aggressive versus Non-aggressive Lung Cancer. 
  NIH, Seattle, WA - 1/1/2013
• Understanding Environmental Factors and Climate Change on Global Public Health, 
  Philadelphia, PA - 1/1/2013
• Global TB/HIV 
  Univesrsity of Addis Ababa, Addis Ababa, Ethiopia - 1/1/2013
• Tropical Pulmonary Eosinophilia, Early Diagnosis of Lung Cancer 
  Univesrsity of Addis Ababa, Addis Ababa, Ethiopia - 1/1/2013
• Following Sigurd Olson’s Dreams of Canoeing the Churchill River to Hudson’s Bay, the Back River in the Barrenlands, and the South Nahanni. 
  Vermilion Community College, Ely, MN - 1/1/2013
• Potholes in the Road to an Early Detection of Lung Cancer Biomarker, 
  Washington, DC - 1/1/2013
• Global Climate Change and Public Health. 
  West Virgina University - 1/1/2013
• New Medical Dvices and Diagnostics in MDR-TB 
  Honolulu, HI - 1/1/2011
• Climate Change and Global Public Health 
  University of Cape Town - 1/1/2011
• Biomarker Discovery and Verification of a Lung Cancer with Somamer Signature Proteomic Technology 
  Aspen, CO - 1/1/2010
• Early Detection of Lung Cancer 
  Lung Cancer Biomarker Center, New York, NY - 1/1/2010
• Global Climate Change: Respiratory and Ecology 
  New Orleans, LA - 1/1/2010
• Emerging Exposures and Respiratory Health: World Trade Center Dust 
  Aspen, CO - 1/1/2009
• NW Greenland Polar Inuit: Global Warming Up Close 
  Explorer’s Club, New York, NY - 1/1/2009
• Asbestos- Related Disease 
  National Museum of the American Indian, Smithsonian Institution, Washington, DC - 1/1/2009
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