WilliamPuMD

PubMed

• Regulation of sarcomere formation and function in the healthy heart requires a titin intronic enhancer.
  Yuri Kim, Seong Won Kim, David Saul, Meraj Neyazi, Manuel Schmid
  The Journal of Clinical Investigation. 2024-12-17
• In vivo proximity proteomics uncovers palmdelphin (PALMD) as a Z-disc-associated mitigator of isoproterenol-induced cardiac injury.
  Cong-Ting Guo, Blake D Jardin, Jun-Sen Lin, Rachelle L Ambroise, Ze Wang
  Acta Pharmacologica Sinica. 2024-12-01
• 1 citations
  Non-Cell-Autonomous Cardiomyocyte Regulation Complicates Gene Supplementation Therapy for-Associated Cardiac Defects in Mice.
  Yueshen Sun, Congting Guo, Zhan Chen, Junsen Lin, Luzi Yang
  JACC. Basic to Translational Science. 2024-11-01

Journal Articles

• Recounting Cardiac Cellular Composition  
  Zhou P, and Pu WT, Circ Res, 1/1/2016
• An IGF1R-Dependent Pathway Drives Epicardial Adipose Tissue Formation After Myocardial Injury  
  Zangi L, Oliveira MS, Ye LY, Ma Q, Sultana N, Hadas Y, Chepurko E, Spater D, Zhou B, Chew WL, Ebina W, Abrial M, Wang QD, Pu WT, and Chien KR, Circulation, 1/1/2016
• Single-Cell Resolution of Temporal Gene Expression during Heart Development  
  DeLaughter DM, Bick AG, Wakimoto H, McKean D, Gorham JM, Kathiriya IS., Hinson JT, Homsy J, Gray J, Pu WT, Bruneau BG, Seidman JG, Seidman CE, Dev Cell, 1/1/2016
• Contribution of Fetal but Not Adult Pulmonary Mesothelium to Mesenchymal Lineages in Lung Homeostasis and Fibrosis  
  von Gise A, Stevens SM, Honor LB, Oh JH, Gao C, Zhou B, and Pu WT, Am J Respir Cell Mol Biol, 1/29/2015
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  Sun Y, Liu CH, SanGiovanni JP, Evans LP, Tian KT, Zhang B, Stahl A, Pu WT, Kamenecka TM, Solt LA, and Chen J, Proc Natl Acad Sci U S A, 1/4/2015
• Epicardium is required for cardiac seeding by yolk sac macrophages, precursors of resident macrophages of the adult heart  
  Stevens SM, Gise Av, VanDusen N, Zhou B, and Pu WT, Dev Biol, 1/1/2015
• Cellular Origin and Developmental Program of Coronary Angiogenesis  
  Tian X, Pu WT, and Zhou B, Circ Res, 1/1/2015
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  Lin Z, and Pu WT, Circ Res, 1/1/2015
• GATA4 represses an ileal program of gene expression in the proximal small intestine by inhibiting the acetylation of histone H3, lysine 27  
  Aronson BE, Rabello Aronson S, Berkhout RP, Chavoushi SF, He A, Pu WT, Verzi MP, and Krasinski SD, Biochim Biophys Acta, 1/27/2014
• Epicardium-to-fat transition in injured heart  
  Liu Q, Huang X, Oh JH, Lin RZ, Duan S, Yu Y, Yang R, Qiu J, Melero-Martin JM, Pu WT, and Zhou B, Cell Res, 1/26/2014
• Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine Myocardial Infarction Model  
  Lin Z, von Gise A, Zhou P, Gu F, Ma Q, Jiang J, Yau AL, Buck JN, Gouin KA, van Gorp PR, Zhou B, Chen J, Seidman JG, Wang DZ, and Pu WT, Circ Res, 1/15/2014
• Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion  
  Zhang H, von Gise A, Liu Q, Hu T, Tian X, He L, Pu W, Huang X, He L, Cai CL, Camargo FD, Pu WT, and Zhou B, J Biol Chem, 1/15/2014
• Harnessing Hippo in the heart: Hippo/Yap signaling and applications to heart regeneration and rejuvenation  
  Lin Z, and Pu WT, Stem Cell Res, 1/6/2014
• Strategies for Cardiac Regeneration and Repair  
  Lin Z, and Pu WT, Science Translational Medicine, 1/1/2014
• Hippo activation in arrhythmogenic cardiomyopathy  
  Hu Y, and Pu WT, Circ Res, 1/1/2014
• Ultrasound-guided Transthoracic Intramyocardial Injection in Mice  
  Prendiville TW, Ma Q, Lin Z, Zhou P, He A, and Pu WT, J Vis Exp, 1/1/2014
• Notching up vascular regeneration  
  Zhang B, and Pu WT, Cell Res, 1/1/2014
• Pi3kcb Links Hippo-YAP and PI3K-AKT Signaling Pathways to Promote Cardiomyocyte Proliferation and Survival  
  Lin Z, Zhou P, von Gise A, Gu F, Ma Q, Chen J, Guo H, van Gorp PR, Wang DZ, and Pu WT, Circ Res, 1/1/2014
• De novo formation of a distinct coronary vascular population in neonatal heart  
  Tian X, Hu T, Zhang H, He L, Huang X, Liu Q, Yu W, He L, Yang Z, Yan Y, Yang X, Zhong TP, Pu WT, and Zhou B, Science, 1/1/2014
• GATA Factors Promote ER Integrity and beta-Cell Survival and Contribute to Type 1 Diabetes Risk  
  Sartori DJ, Wilbur CJ, Long SY, Rankin MM, Li C, Bradfield JP, Hakonarson H, Grant SF, Pu WT, Kushner JA, Mol Endocrinol, 1/1/2014
• WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland  
  Bandiera R, Vidal VP, Motamedi FJ, Clarkson M, Sahut-Barnola I, von Gise A, Pu WT, Hohenstein P, Martinez A, Schedl A, Dev Cell, 1/1/2013
• Peritruncal coronary endothelial cells contribute to proximal coronary artery stems and their aortic orifices in the mouse heart  
  Tian X, Hu T, He L, Zhang H, Huang X, Poelmann RE, Liu W, Yang Z, Yan Y, Pu WT, Zhou B, PLoS One, 1/1/2013
• Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction  
  Zangi L, Lui KO, von Gise A, Ma Q, Ebina W, Ptaszek LM, Spater D, Xu H, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT,..., Nat Biotechnol, 1/1/2013
• Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification  
  Zhou P, Zhang Y, Ma Q, Gu F, Day DS, He A, Zhou B, Li J, Stevens SM, Romo D, Pu WT, Proc Natl Acad Sci U S A, 1/1/2013
• A simple method for deriving functional MSCs and applied for osteogenesis in 3D scaffolds  
  Zou L, Luo Y, Chen M, Wang G, Ding M, Petersen CC, Kang R, Dagnaes-Hansen F, Zeng Y, Lv N, Ma Q, Le DQ, Besenbacher F, Bolund L, Jensen TG, Kjems J, Pu WT, Bunger C, Sci Rep, 1/1/2013
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Books/Book Chapters

• Muscle: Fundamental Biology and Mechanisms of Disease 
  Chapter: Mammalian Heart Regeneration 
  Zhou B, and Lin Z, Pu WTEditors: Olson, E.N. and Hill, J.H..Elsevier2012
• Molecular Basis of Heart Failure. In Heart Failure: A Companion to Braunwald's Heart Disease 
  Page 10 - 40Izumo S, and Pu WTEditors: Mann, D. L..Saunders, Philadelphia, PA2004

Abstracts/Posters

• Transcriptional Regulation of Cardiovascular Development and Disease
  Pu WT, Shanghai Jiaotung University; Peking University Institute of Molecular Medicine, Shanghai, China, 2016; Peking, China, 2016, 1/1/2016
• Applications of Stem Cell Biology to Heart Disease
  Pu WT, Multiple Locations, 2015, 2016, 1/1/2016
• YAP regulation of heart growth and regeneration
  Pu WT, American Heart Association Scientific Sessions, New Orleans, LA, 1/1/2016
• Epigenetic and Transcriptional Regulation in the Cardiovascular System
  Pu WT, American Heart Association Scientific Sessions, New Orleans, LA, 1/1/2016
• ROS cause abnormal calcium handling in Barth syndrome stem cell-derived cardiomyocytes
  Pu WT, Barth Syndrome Foundation Meeting, Tampa, FL, 1/1/2016
• An IGF1R-dependent Pathway Drives Adipogenic Differentiation of Epicardial Progenitor Cells Following MI
  Pu WT, American Heart Association Basic Cardiovascular Sciences Meeting, Phoenix, AZ, 1/1/2016
• Topics in heart development and disease
  Pu WT, Developmental Biology Seminar Series, Children’s Hospital of Philadelphia, Philadelphia, PA, 1/1/2016
• Modeling heart disease using human stem cell-derived cardiomyocytes
  Pu WT, Department of Anesthesia, NYU Medical Center, New York, NY, 1/1/2016
• Transcriptional regulation of heart growth
  Pu WT, Keynote Address, Integrative Vascular Biology Training Program/McAllister Heart Institute, University of North Carolina, Chapel Hill, NC, 1/1/2016
• Applications of Stem Cell Biology to Heart Disease
  Pu WT, Cardiovascular Grand Rounds University of Arizona Sarver Heart Center, Tuscon, AZ, 1/1/2016
• Ribosomal-RNA profiling in lineage specific transcriptome analysis, Next-Generation Transcriptome Analysis of Cardiovascular Diseases
  Pu WT, American Heart Association Scientific Sessions, Orlando, FL, 1/1/2015
• Transcriptional regulation of cardiac growth and development
  Pu WT, Multiple Locations, 2014, 2015, 1/1/2015
• Applications of Stem Cell Biology to Heart Disease
  Pu WT, Mount Sinai School of Medicine, New York, NY, 1/1/2015
• Using genome editing to study mitochondrial myopathies in iPSC-CMs
  Pu WT, Penn Cardiovascular Institute Symposium on Advances in Genome Editing University of Pennsylvania, Philadelphia, PA, 1/1/2015
• Applications of Stem Cell Biology to Heart Disease
  Pu WT, Nationwide Children’s Hospital, Columbus, OH, 1/1/2015
• Pi3kcb Links Hippo-YAP and PI3K-AKT Signaling Pathways to Promote Cardiomyocyte Proliferation and Survival
  Pu WT, American Heart Association Scientific Sessions, “Best of Circulation Research”, Orlando, FL, 1/1/2015
• Transcriptional regulation of heart growth and function
  Pu WT, Institute of Molecular Medicine, Texas Heart Institute, Houston, TX, 1/1/2015
• Transcriptional and epigenetic regulation of cardiomyocyte maturation
  Pu WT, Progenitor Cell Biology Consortium Cardiovascular Workshop, Stanford, Palo Alto, CA, 1/1/2014
• An iPSC-CM model of the mitochondrial cardiomyopathy of Barth Syndrome
  Pu WT, American Heart Association Basic Cardiovascular Sciences Meeeting; American Heart Association Scientific Sessions, Las Vegas, CA, 2014; Chicago, IL, 2014, 1/1/2014
• IGF1 stimulates epicardial adipose tissue formation after myocardial infarction
  Pu WT, Progenitor Cell Biology Consortium Annual Meeting, Stanford, CA, 1/1/2014
• Applications of Stem Cell Biology to Heart Disease
  Pu WT, University of Toronto, Toronto, Canada, 1/1/2014
• A human cardiomyocyte model of Barth syndrome cardiomyopathy
  Pu WT, Barth Syndrome Foundation Biannual Meeting, Family Sessions, “Scientific Breakthroughs”, Tampa Bay, FL, 1/1/2014
• Modeling Barth syndrome with iPSC-derived cardiomyocytes
  Pu WT, Barth Syndrome Foundation Biannual Meeting, Scientific Session, Tampa Bay, FL, 1/1/2014
• Applications of Stem Cell Biology to Heart Disease
  Pu WT, Weill Cornell Medical School, New York City, NY, 1/1/2014
• Modeling Barth syndrome with iPSC-derived cardiomyocytes
  Pu WT, Stanford Cardiovascular Institute Regenerative Medicine Symposium, Stanford, Palo Alto, CA, 1/1/2014
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Lectures

• VEGF promotes RNAPII pausing release through an ETS1-Brd4 complex to stimulate angiogenesis 
  1/1/2016
• Transcriptional Regulation of heart growth and function 
  1/1/2016
• Strategies for cardiac regeneration 
  1/1/2016
• AAV cardiac gene therapy 
  1/1/2016
• Modeling heart disease using human induced pluripotent stem cells 
  1/1/2016
• Non-canonical mechanisms of Eed-mediated transcriptional repression in the postnatal heart 
  1/1/2015
• Modeling cardiac disease using induced pluripotent stem cells 
  1/1/2015
• IGF1-driven formation of epicardial adipose tissue after myocardial infarction 
  1/1/2014
• Epigenetic regulation of angiogenesis 
  1/1/2014
• Modeling Barth syndrome with patient-specific iPSC-derived cardiomyocytes 
  1/1/2013
• Driving cardiac repair with modified RNA 
  1/1/2013
• Transcriptional and epigenetic regulation of angiogenesis 
  1/1/2013
• Transcriptional regulation of heart development and disease 
  1/1/2013
• Epicardium in heart development and disease 
  1/1/2011
• Epigenetic regulation of heart development 
  1/1/2011
• Transcriptional regulation in the developing and diseased heart 
  1/1/2011
• Identification of cardiac transcriptional regulatory elements by ChIP-seq 
  1/1/2011
• Cardiovascular imaging in mice 
  1/1/2011
• Regulation of heart development and function by a GATA4-FOG2 transcriptional complex 
  1/1/2010
• Epicardial function in adult heart injury 
  1/1/2010
• Regulation of cardiac morphogenesis by the transcription factor GATA4 
  1/1/2006
• Regulation of cardiac development and postnatal function by Gata4 
  1/1/2006
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Other

• Functional analysis of DNA-binding domain of GCN4, a bZIP transcription factor 
  Pu, WT
  1/1/1993