WilliamChunHahnMDPhD

Genitourinary Oncology, Hematologic Oncology

Professor of Medicine, Dana-Farber Cancer Institute

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Office
450 Brookline Ave
# Dana-Far
Boston, MA 02215
Phone+1 617-632-2641

Fax+1 617-632-4005

Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1996 - 1999
Massachusetts General HospitalResidency, Internal Medicine, 1994 - 1997
Harvard Medical SchoolClass of 1994

PubMed

286 citations
The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis
Mark Pomerantz, Fugen Li, David Y. Takeda, Romina E. Lenci, Apurva Chonkar
Nature Genetics. 2015-11-01
65 citations
Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer.
Sylvan C. Baca, David Y. Takeda, Ji-Heui Seo, Justin H. Hwang, Sheng-Yu Ku
Nature Communications. 2021-03-30
2358 citations
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
David A. Barbie, Pablo Tamayo, Jesse S. Boehm, So Young Kim, Susan Moody
Nature. 2009-11-05

Journal Articles

Selective Gene Dependencies in MYCN-Amplified Neuroblastoma Include the Core Transcriptional Regulatory Circuitry
William C Hahn, Todd R Golub, A Thomas Look, Adam D Durbin, Neekesh V Dharia, Kimberly Stegmaier, Nature
Article Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis
William C Hahn, Levi A Garraway, Zhe Li, ScienceDirect
Germline Cancer Susceptibility Gene Variants, Somatic Second Hits, and Survival Outcomes in Patients with Resected Pancreatic Cancer
Richard F Dunne, Leona A Doyle, William C Hahn, Jason L Hornick, Andrea J Bullock, Sapna Syngal, Albert C Koong, Natalia Khalaf, Brian M Wolpin, Douglas A Rubinson, Da..., Nature
Genome-Scale Analysis Identifies Paralog Lethality as a Vulnerability of Chromosome 1p Loss in Cancer
William C Hahn, Srinivas R Viswanathan, Nature
Institutional Implementation of Clinical Tumor Profiling on an Unselected Cancer Population
Khanh Do, Lauren L Ritterhouse, William C Hahn, Geoffrey I Shapiro, Barrett J Rollins, Neal I Lindeman, Alanna Church, Geoffrey R Oxnard, Bruce E Johnson, Frank C Kuo,..., The Journal of Clinical Investigation
Integrated Genetic and Pharmacologic Interrogation of Rare Cancers
Andrew L Hong, Katherine A Janeway, Brian D Crompton, Kimberly Stegmaier, Levi A Garraway, Alanna J Church, Stuart L Schreiber, William C Hahn, Nature
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Abstracts/Posters

Functional Characterization of E3 Ligases and Their Regulators: Therapeutic Implications for Development of New Proteolysis-Targeting Chimeric Degraders of Oncoproteins
William C. Hahn, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Systematic Characterization of Genes Representing Preferential Molecular Vulnerabilities for Myeloma Cells Compared to Other Neoplasias _ Implications for the Biology ...
William C. Hahn, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

KSQ Therapeutics Raises $80 Million Series C for Cancer TherapiesSeptember 28th, 2018
Cambridge Startup KSQ Raises Another $80m, Plans to Start Trials of Cancer DrugsSeptember 28th, 2018
WBUR Invitation: Ask Leaders Your Big-Picture Questions on CancerJanuary 5th, 2018
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Druggable Genetic Lesions In Pediatric AstrocytomaNational Cancer Institute2011–2012
Regulation And Function Of Htert In Human CellsNational Institute On Aging2010–2012
Investigations On The Role Of The CDK8 Oncogene In Colon CancerNational Cancer Institute2010–2012
Regulation And Function Of Ikke In Breast Cancer Initiation And MaintenanceNational Cancer Institute2009–2012
Gene Function Manipulation CoreNational Cancer Institute2009–2012
Interactions Of The SV40 Small T Antigen And PP2A In Human Cell TransformationNational Cancer Institute2004–2012
Functional Annotation Of Cancer Genomes: Tcga, Glioblastoma And Ovarian CancerNational Cancer Institute2009–2010
Integrated Genomic Approaches To Identify And Validate Cancer TargetsNational Cancer Institute2008–2010
Regulation And Function Of Telomerase In Human CellsNational Institute On Aging2004–2008
New Models Of Human CancerNational Cancer Institute2001–2005