WilliamCarrollMD

PubMed

• 797 citations
  Improved Survival for Children and Adolescents With Acute Lymphoblastic Leukemia Between 1990 and 2005: A Report From the Children's Oncology Group
  Stephen P. Hunger, Xiaomin Lu, Meenakshi Devidas, Bruce M. Camitta, Paul S. Gaynon
  Journal of Clinical Oncology. 2012-05-10
• 412 citations
  Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute l...
  Richard C. Harvey, Charles G. Mullighan, I-Ming Chen, Walker Wharton, Fady M. Mikhail
  Blood. 2010-07-01
• 204 citations
  Targetable kinase gene fusions in high-risk B-ALL: a study from the Children's Oncology Group.
  Shalini C. Reshmi, Richard C. Harvey, Kathryn G. Roberts, Eileen Stonerock, Amy Smith
  Blood. 2017-06-22

Journal Articles

• Loss of TBLXR1 disrupts glucocorticoid receptor recruitment to chromatin and results in glucocorticoid resistance in childhood B-Lymphoblastic leukemia model  
  Jones CL, Bhatla T, Wang J, Bourgeois W, Bitterman D, Raetz E, Morrison D, Teachey D, Garabedian M, Carroll WL, J Biol Chem, 6/1/2014
• A Prospective Study of Anxiety, Depression, and Behavioral Changes in the First Year after Diagnosis of Childhood Acute Lymphoblastic Leukemia  
  Myers RM, Balsamo L, Lu X, Devidas, M, Hunger SP, Carroll WL, Winick NJ, Maloney KW, and Kadan-Lottick NS, Cancer, 5/1/2014
• Philadelphia chromosome negative very high risk acute lymphoblastic leukemia (ALL) in children and adolescents: results from children's oncology group (COG) study AALL...  
  Schultz KR, Devidas M, Bowman WP, Aledo A, Slayton WB, Sather H, Zheng HW, Davies SM, Gaynon PS, Trigg M, Rutledge R, Jorstad D, Carroll AJ, Heerema N, Winick N, Borow..., Leukemia, 4/1/2014
• The addition of sirolimus to tacrolimus/methotrexate GVHD prophylaxis in children with ALL: a phase III COG/PBMTC trial  
  Pulsipher MA, Langholz B, Wall DA, Schultz KR, Bunin N, Carroll WL, Raetz E, Gardner S, Gastier-Foster JM, Howrie D, Goyal RK, Douglas J, Borowitz MJ, Barnes Y, Teache..., Blood, 3/1/2014
• Refining prognosis in BCR-ABL1-positive ALL  
  Raetz EA, Carroll WL, Blood, 3/1/2014
• Epigenetic deregulation in pediatric Acute Lymphoblastic Leukemia  
  Chatterton Z, Morenos L, Mechinaud F, Ashley DM , Craig JM , Sexton-Oates A, Halemba M, Parkinson-Bates M, Ng J, Morrison D, Carroll WL, Saffery R, Wong NC, Epigenetics, 3/1/2014
• Clinical Cancer Advances 2013: Annual Report on Progress Against Cancer From the American Society of Clinical Oncology  
  Patel JD, Krilov L, Adams S, Aghajanian C, Basch E, Brose MS, Carroll WL, de Lima M, Gilbert MR, Kris MG, Marshall JL, Masters GA, O'Day SJ, Polite B, Schwartz GK, Sha..., J Clin Oncol, 1/1/2014
• Long term follow-up of imatinib in pediatric philadelphia chromosome-positive acute lymphoblastic leukemia: children's oncology group study AALL0031  
  Schultz KR, Carroll A, Heerema NA, Bowman WP, Aledo A, Slayton WB, Sather H, Devidas M, Zheng HW, Davies SM, Gaynon PS, Trigg M, Rutledge R, Jorstad D, Winick N, Borow..., Leukemia, 1/1/2014
• Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse  
  Perez-Andreu V, Roberts KG, Harvey RC, Yang W, Cheng C, Pei D, Xu H, Gastier-Foster J, E S, Lim JY, Chen IM, Fan Y, Devidas M, Borowitz MJ, Smith C, Neale G, Burchard ..., Nat Genet, 12/1/2013
• HMGA1 overexpression correlates with relapse in childhood B-lineage acute lymphoblastic leukemia  
  Roy S, Di Cello F, Kowalski J, Hristov AC, Tsai HL, Bhojwani D, Meyer JA, Carroll WL, Belton A, Resar LM, Leuk Lymphoma, 11/1/2013
• A Phase I Study of EZN-3042, a Novel Survivin Messenger Ribonucleic Acid (mRNA) Antagonist, Administered in Combination with Chemotherapy in Children with Relapsed Acu...  
  Raetz EA, Morrison D, Romanos-Sirakis E, Gaynon P, Sposto R, Bhojwani D, Bostrom B, Brown P, Eckroth E, Cassar J, Malvar J, Buchbinder A, Carroll WL, J Pediatr Hematol Oncol, 10/1/2013
• Intrachromosomal Amplification of Chromosome 21 Is Associated with Inferior Outcomes in Children with Acute Lymphoblastic Leukemia on Contemporary Standard Risk Childr...  
  Heerema NA, Carroll AJ, Devidas M, Loh ML, Borowitz MJ, Gastier-Foster JM, Larsen EC, Mattano LA, Maloney KW, Willman CL, Wood B, Winick NJ, Carroll WL, Hunger SP, Rae..., J Clin Oncol, 9/1/2013
• BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint  
  Swaminathan S, Huang C, Geng H, Chen Z, Harvey R, Kang H, Ng C, Titz B, Hurtz C, Sadiyah MF, Nowak D, Thoennissen GB, Rand V, Graeber TG, Koeffler HP, Carroll WL, Will..., Nature Medicine, 8/1/2013
• Erwinia Asparaginase Achieves Therapeutic Activity after PEG-asparaginase Allergy: A Report from the Children’s Oncology Group  
  Salzer WL, Asselin B, Supko JG, Devidas M, Kaiser NA, Plourde P, Winick NJ, Reaman GH, Raetz E, Carroll WL, Hunger SP, Blood, 7/1/2013
• Screening for gene mutations: will identification of NT5C2 mutations help predict the chance of relapse in acute lymphoblastic leukemia?  
  Meyer JA, Carroll WL, Bhatla T, Carroll WL, Expert Review of Hematology, 6/1/2013
• Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia  
  Hunger SP, Loh ML, Whitlock JA, Winick NJ, Carroll WL, Devidas M, Raetz EA; COG Acute Lymphoblastic Leukemia Committee, Pediatric Blood Cancer, 6/1/2013
• Novel Susceptibility Variants at 10p1231-122 for Childhood Acute Lymphoblastic Leukemia in Ethnically Diverse Populations  
  Xu H, Yang W, Perez-Andreu V, Devidas M, Fan Y, Cheng C, Pei D, Scheet P, Burchard EG, Eng C, Huntsman S, Torgerson DG, Dean M, Winick NJ, Martin PL, Camitta BM, Bowma..., J Natl Cancer Inst, 5/1/2013
• Safety in numbers: hyperdiploidy and prognosis  
  Carroll WL, Blood, 3/1/2013
• Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project  
  Loh ML, Zhang J, Harvey RC, Roberts K, Payne-Turner D, Kang H, Wu G, Chen X, Becksfort J, Edmonson M, Buetow KH, Carroll WL, Chen IM, Wood B, Borowitz MJ, Devidas M, G..., Blood, 1/1/2013
• SOX4 enables oncogenic survivalsignals in acute lymphoblastic leukemia  
  Ramezani-Rad P, Geng H, Hurtz C, Chan LN, Chen Z, Jumaa H, Melnick A, Paietta E, Carroll WL, Willman CL, Lefebvre V, Müschen M, Blood, 1/1/2013
• Genome-wide association study identifies germline polymorphisms associated withrelapse of childhood acute lymphoblastic leukemia  
  Yang JJ, Cheng C, Devidas M, Cao X, Campana D, Yang W, Fan Y, Neale G, Cox N, Scheet P, Borowitz MJ, Winick NJ, Martin PL, Bowman WP, Camitta B, Reaman GH, Carroll WL,..., Blood, 11/1/2012
• Children, Adolescents and Young Adults with Leukemia: The Empty Half of the Glass is Growing  
  Hunger SP, Lu X, Devidas M, Camitta BM, Gaynon PS, Winick N, Reaman GH, Carroll WL. Reply to A. Bleyer et al, J Clin Oncol, 11/1/2012
• Modifications to Induction Therapy Decrease Risk of Early Death in Infants with Acute Lymphoblastic Leukemia Treated on Children’s Oncology Group P9407  
  Salzer WL, Jones TL, Devidas M, Hilden JM, Winick N, Hunger SP, Carroll WL, Camitta B, Dreyer ZE, Pediatric Blood Cancer, 11/1/2012
• Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia  
  Roberts KG, Morin RD, Zhang J, Hirst M, Zhao Y, Su X, Chen SC, Payne-Turner D, Churchman ML, Harvey RC, Chen X, Kasap C, Yan C, Becksfort J, Finney RP, Teachey DT, Mau..., Cancer Cell, 8/1/2012
• Pilot Study of Nelarabine in Combination With Intensive Chemotherapy in High-Risk T-Cell Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group  
  Dunsmore KP, Devidas M, Linda SB, Borowitz MJ, Winick N, Hunger SP, Carroll WL, Camitta BM, J Clin Oncol, 8/1/2012
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Books/Book Chapters

• Cancer in Children and Adolescents. 
  Editors: Carroll WL, Finlay J.Jones and Bartlett Publishers, Inc.2009
• 100 Questions & Answers About Your Child’s Cancer. 
  Carroll WL, Reisman JJones and Bartlett Publishers, Inc.Edition 2nd,2004
• Rudolph’s Textbook of Pediatrics. 
  Chapter: Hematological Diseases of the Newborn Infant. 
  Slayton W and Carroll WLEditors: CD Rudolph, AM Rudolph, M Hostetter, G Lister and N Siegel.McGraw-Hill Medical Publishing Co.2003
• Immunoglobulin Gene Expression In Development and Disease. 
  Chapter: Analysis of Hypermutation in a Mixed Tcell Receptor B/ Immunoglobulin Heavy Chain Passenger Transgene. 
  Page 192 - 195Johnston JM, Ihyer SR, Tai KF, Smith RS, Nadon NL, and Carroll WLEditors: P Casali and L Silberstein.Annals of the New York Academy of Sciences, New York, NY1995
• Immunoglobulin Gene Expression In Development and Disease. 
  Chapter: The Immunoglobulin Gene Repertoire to Haemophilus influenza Type b. 
  Page 374 - 378Carroll WL, Shackelford PG, and Adderson EEEditors: P Casali and L Silberstein.Annals of the New York Academy of Sciences, New York, NY1995
• Pediatric Medicine. 
  Chapter: Oncology. 
  Page 607 - 665Carroll WL and Schwartz ALEditors: Avery ME and First LR.Williams and Wilkins, Baltimore, MDEdition 2nd,1994
• Samter's Immunological Diseases. 
  Chapter: Immunoglobulins. 
  Page 33 - 51Carroll WL Korsmeyer SJEditors: MM Frank, KF Austen, HN Claman and ER Unanue.Little Brown and Co., Boston, MA1994
• Haemophilus influenzae b Conjugate Vaccines. 
  Chapter: Molecular Basis of Antibody Diversity 
  Page 207 - 229Carroll WL, EE Adderson, AH Lucas, GJ Silverman, MG Scott, MH Nahm, RA Insel and PG ShackelfordEditors: RW Ellis and DG Granoff.Marcel Dekker, New York, NY1994
• Current Pediatric Therapy. 
  Chapter: Malignant Lymphoma. 
  Page 278 - 283Carroll WLEditors: Burg FD, Ingelfinger IR and Wald ER.W.B. Saunders Co., Philadelphia, PAEdition 14th,1993
• Clinical Pediatric Oncology 
  Chapter: Chapter 3: Molecular oncology. 
  Page 29 - 68Carroll WL and Schwartz ALEditors: Fernbach DJ, Vietti TJ.CV Mosby, St. Louis, MOEdition 5th,1991
• Comprehensive Textbook of Oncology. 
  Chapter: Chapter 144: Implications of molecular biology for the diagnosis, classification, prognosis and treatment of pediatric Cancers. 
  Page 1476 - 1485Carroll WL and Brodeur GMEditors: Moosa AR, Robson MC and Schimpff SC.Williams and Wilkins, Baltimore, MD1991
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Abstracts/Posters

• The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia
  William L. Carroll, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Germline RUNX1 Variation and Predisposition to T-Cell Acute Lymphoblastic Leukemia in Children
  William L. Carroll, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• FLT3 Inhibitor Correlative Laboratory Assays Impact Outcomes in KMT2A-Rearranged Infant Acute Lymphoblastic Leukemia (ALL) Patients Treated with Lestaurtinib: AALL0631...
  William L. Carroll, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• NT5C2 Germline Variants Alter Thiopurine Metabolism and Are Associated with Acquired NT5C2 Relapse Mutations in Childhood Acute Lymphoblastic Leukaemia
  William Carroll, MD, Nature, Orlando, FL, 12/9/2019
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Lectures

• Treating Childhood Leukemia in the Age of Genomics. 
  Mount Sinai Medical Center, New York, NY - 2/13/2014
• The Evolutionary Forces That Drive Treatment Failure In Childhood Cancer – Lessons Learned from Treating Acute Lymphoblastic Leukemia. 
  Hershey, PA - 10/25/2013
• The Genetic and Molecular Evolution of Relapsed ALL-Clues to Drug Resistance Pathways. 
  Washington, DC - 9/16/2013
• Molecular mechanisms that guide drug resistance and relapse in childhood leukemia. 
  New York, NY - 8/5/2013
• Evolution of Drug Resistance In Childhood Acute Lymphoblastic Leukemia. 
  Bethesda, MD - 5/30/2013
• Childhood Cancer in the DNA Century. 
  Children's Hospital Colorado, Denver , CO - 5/3/2013
• The Genomics of Relapsed Acute Lymphoblastic Leukemia: Insights into the Evolutionary Forces That Guide Tumor Recurrence. 
  Children's Hospital Colorado, Denver , CO - 5/2/2013
• The Genomic Landscape of Childhood Leukemia. 
  Irvine, CA - 10/25/2012
• Insights into the Molecular and Cellular Origin of Cancer Recurrence - Lessons from Childhood Leukemia. 
  Los Angeles, CA - 7/15/2012
• The Role of Epigenetics in Relapsed Childhood ALL: Epigenetics as a Modifiable Cause of Acquired Chemoresistance. 
  New Orleans, LA - 5/11/2012
• Therapeutic Advances in the Treatment of Childhood Acute Lymphoblastic Leukemia. Key Note Lecture 
  Cape Town, South Africa - 3/22/2012
• Pediatric Cancer Therapy in the Age of Genomics. 
  Stony Brook, NY - 2/29/2012
• Practical Aspects of Implementing a Genomics-Based Personalized Medicine Program in an NCI-Designated Cancer Center. Panel 
  Washington, DC - 10/17/2011
• The Impact of Comprehensive Genomics in New Treatments for Acute Lymphoblastic Leukemia (ALL). Speaker 
  Washington, DC - 7/29/2011
• Personalized Medicine for Cancer Hype or Reality? 
  Children’s Hospital of Orange County, Orange, CA - 3/16/2011
• Genomics and Childhood Leukemia: A Model for Personalized Medicine. 
  University of Missouri School of Medicine, Columbia, MO - 11/12/2010
• Personalized Medicine in the DNA Century: Lessons from Childhood Leukemia. Key note address. 
  University of Missouri School of Medicine, Columbia, MO - 11/12/2010
• Childhood Cancer as a Model for Personalized Medicine. 
  Columbus, OH - 10/28/2010
• The Translational Biology of Relapsed Acute Lymphoblastic Leukemia. 
  Memorial Sloan Kettering Cancer Center, New York, NY - 6/10/2010
• The Translational Biology of Childhood Leukemia: A Contemporary Model for Personalized Medicine. 
  St. Louis, MO - 5/28/2010
• How to Make it in Academic Medicine: Lessons That I Have Learned. 
  Los Angeles, CA - 4/29/2010
• Translational Themes in Childhood ALL. 
  Los Angeles, CA - 4/27/2010
• Personalized Medicine: Dream or Reality? Lessons from Childhood Acute Lymphoblastic Leukemia. 
  Los Angeles, CA - 4/23/2010
• Using High Throughput Genomics to Discover Drug- Resistance Pathways that Operate In Vivo. 
  Montreal, Canada - 4/9/2010
• Introduction to Cancer. 
  New York, NY - 1/12/2010
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