WayneShrefflerMDPhD

PubMed

• Prospective association between food protein-induced allergic proctocolitis in infancy and constipation after age 3.
  Michael Marget, Corey Baker, Isabel O'Connell, Wayne G Shreffler, Qian Yuan
  Journal of Pediatric Gastroenterology and Nutrition. 2024-11-25
• The use and implementation of omalizumab as food allergy treatment: Consensus-based guidance and Work Group Report of the Adverse Reactions to Foods Committee of the A...
  Aikaterini Anagnostou, J Andrew Bird, Sharon Chinthrajah, Timothy E Dribin, David M Fleischer
  The Journal of Allergy and Clinical Immunology. 2024-11-22
• Immunomodulatory metabolites in IgE-mediated food allergy and oral immunotherapy outcomes based on metabolomic profiling.
  Yamini V Virkud, Jennifer N Styles, Rachel S Kelly, Sarita U Patil, Bert Ruiter
  Pediatric Allergy and Immunology. 2024-11-01

Journal Articles

• Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children with Peanut Allergy  
  Todd D Green, David M Fleischer, Hey Chong, R Sharon Chinthrajah, Edwin H Kim, Stacie M Jones, Robert Wood, Bruce J Lanser, Lynda Schneider, Jacqueline A Pongracic, Wa..., JAMA
• Evidence of pathway-specific basophil anergy induced by peanut oral immunotherapy in peanut-allergic children  
  Thyagarajan A, Jones S, Calatroni A Pons L, Kulis M, Woo C, Kamalakannan M, Vickery B, Scurlock A, Burks AW, Shreffler WG, Clin Exp Allergy, 1/1/2012
• Consortium for Food Allergy Research (CoFAR). Oral immunotherapy for treatment of egg allegry in children  
  Burks AW, Jones SM, Wood RA, Fleischer DM, Sicherer SH, Lindblad RW, Stablein D, Henning AK, Vickery BP, Liu AH, Scurlock AM, Shreffler WG, Plaut M, Sampson HA, N Engl J Med, 1/1/2012
• Immunology in the Clinic Review Series; focus on allergies: basophils as biomarkers for assessing immune modulation  
  Patil S, Shreffler WG, Clin Exp Immunol, 1/1/2012
• Innate immunostimulatory properties of allegens and their relevance to food allergy  
  Ruiter B, Shreffler WG, Semin Immunopathol, 1/1/2012
• The role of dendritic cells in food allergy  
  Ruiter B, Shreffler WG, J All Clin Immunol, 1/1/2012
• Determinants of food allergy  
  Masilamani, M., Commins, S., & Shreffler, W, Immunology and Allergy Clinics of North America, 1/1/2012
• Both variability and level of mouse allergen exposure influence the phenotype of the immune response in workers at a mouse facility  
  Peng RD, Paigen B, Eggleston PA, Hagberg KA, Krevans M, Curtin-Brosnan J, Benson C, Shreffler WG, Matsui EC, J Allergy Clin Immunol, 1/1/2011
• Sublingual immunotherapy for peanut allergy: clinical and immunologic evidence of desensitization  
  Kim EH, Bird JA, Kulis M, Laubach S, Pons L, Shreffler WG, Steele P, Kamilaris J, Vickery B, Burks AW, J Allergy Clin Immunol, 1/1/2011
• Walnut Allergy in Peanut-Allergic Patients: Significance of Sequential Epitopes of Walnut Homologous to Linear Epitopes of Ara h 1, 2 and 3 in Relation to Clinical Rea...  
  Rosenfeld L, Shreffler W, Bardina L, Niggeman B, Wahn U, Sampson HA, Beyer K, Int Arch Allergy Immunol, 1/1/2011
• Microarrayed recombinant allergens for diagnostic testing  
  Shreffler WG, J All Clin Immunol, 1/1/2011
• Identification of IgE sequential epitopes of lentil (Len c 1) by means of peptide microarray immunoassay  
  Vereda A, Andreae DA, Lin J, Shreffler WG, Ibanez MD, Cuesta-Herranz J, Bardina L, Sampson HA, J Allergy Clin Immunol, 1/1/2010
• Immunologic features of infants with milk or egg allergy enrolled in an observational study (CoFAR) of food allergy  
  Sicherer SH, Wood RA, Stablein D, Burks AW, Liu AH, Jones SM, Fleischer DM, Leung DYM, Grishin A, Mayer L, Shreffler WG, Lindblad R, Sampson HA, J Allergy Clin Immunol, 1/1/2010
• Correlation of IgE/IgG4 milk epitopes and affinity of milk-specific IgE antibodies with different phenotypes of clinical milk allergy  
  Wang J, Lin J, Bardina L, Goldis M, Nowak-Wegrzayn A, Shreffler WG, Sampson HA, J Allergy Clin Immunol, 1/1/2010
• The Urban Environment and Childhood Asthma (URECA) birth cohort study; design, methods, and study population  
  Gern JE, Visness CM, Gergen PJ, Wood RA, Bloomberg GR, O’Connor GT, Kattan M, Sampson HA, Witter FR, Sandel MT, Shreffler WG, Wright RJ, Arbes SJ Jr, Busse WW, BMC Pulm Med, 1/1/2009
• The perfectly potent peanut  
  Shreffler WG, J All Clin Immunol, 1/1/2009
• Microarrayed allergen molecules for diagnostics of allergy  
  Lin J, Bardina L, Shreffler WG, Methods Mol Biol, 1/1/2009
• Epinephrine treatment is infrequent and biphasic reactions are rare in food- induced reactions during oral food challenges in children  
  Jarvinen KM, Amalanayagam S, Shreffler WG, Noone S, Sicherer SH, Sampson HA, Nowak- Wegrzyn A, J Allergy Clin Immunol, 1/1/2009
• Development of a novel peptide microarray for large-scale epitope mapping of food allergens  
  Lin J, Bardina L, Shreffler WG, Andreae DA, Ge Y, Wang J, Bruni FM, Fu Z, Han Y, Sampson HA, J Allergy Clin Immunol, 1/1/2009
• Clinical efficacy and immune regulation with peanut oral immunotherapy  
  Jones SM, Pons L, Roberts JL, Scurlock AM, Perry TT, Kulis M, Shreffler WG, Steele P, Henry KA, Adair M, Francis JM, Durham S, Vickery BP, Zhong X, Burks AW, J All Clin Immunol, 1/1/2009
• Allergen-specific basophil activation associated with clinical tolerance in patients with milk allergy  
  Wanich N, Nowak-Wegrzyn A, Sampson HA, Shreffler WG, J All Clin Immunol, 1/1/2009
• The association of allergen-specific regulatory T cells with the onset of clinical tolerance to milk protein  
  Shreffler WG, Wanich N, Moloney M, Nowak-Wegrzyn A, Sampson HA, J All Clin Immunol, 1/1/2009
• Immunologic changes in children with egg allergy ingesting extensively heated egg  
  Lemon-Mule H, Sampson HA, Sicherer SH, Shreffler WG, Noone S, Nowak-Wegrzyn A, J All Clin Immunol, 1/1/2008
• Tolerance to extensively heated milk in children with cow’s milk allergy  
  Nowak-Wegrzyn A, Bloom K, Sicherer SH, Shreffler WG, Noone S, Wanich N, Sampson HA, J All Clin Immunol, 1/1/2008
• Peanut epitopes for IgE and IgG4 in peanut-sensitized children in relation to severity of peanut allergy  
  Flinterman AE, Knol EF, Andreae DA, Bardina L, den Hartog Jager CF, Pasmans SG, Bruijnzeel- Koomen CA, Sampson HA, van Hoffen E, Shreffler WG, J All Clin Immunol, 1/1/2008
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Abstracts/Posters

• Tolerance of Baked Milk in a Subset of Patients with Cow’s Milk-Mediated Eosinophilic Esophagitis
  J Leung, A Katz, Q Yuan, S Iyengar, P Permaul, JE Walter, J Ramakrishna, WG Shreffler, P Hesterberg, 2013 AAAAI Annual Meeting, San Antonio, TX, 1/1/2013
• Increase in Antigen-specific B Cells During Peanut Oral Immunotherapy Using Novel Tetramer-based Approach
  SU Patil, S Kubala, A Brennan, A Ma, J Moon, WG Shreffler, 2013 AAAAI Annual Meeting, San Antonio, TX, 1/1/2013
• Human basophils internalize antigen in an IgE-dpendent fashion and express costimulatory molecules
  S Patil, A Ma, G Lund, WG Shreffler, 2012 EAACI Congress, Geneva, Switzerland, 1/1/2012
• Human dendritic cells stimulated with peanut express high levels of ALDH1A2 and induce RA-sensitive genes in naïve T cells
  B Ruiter, G Grishina, HA Sampson, WG Shreffler, 2011 EAACI-GA2LEN 9th Immunology Winter School, Davos, Switzerland, 1/1/2011
• IgE sensitization to milk and peanut are associated with increased IL-4 but not GATA-3. Oral Abstract Session 5604
  Shreffler WG, AAAAI Annual Meeting, New Orleans, LA, 1/1/2010
• CS Woo, A Ma, S Yoo, W Chan, HA Sampson, WG Shreffler, 2010 AAAAI Annual Meeting, New Orleans, LA, 1/1/2010
• Human dendritic cells stimulated with peanut allergen express high levels of ALDH1A2 and induce RA-sensitive genes in naïve T cells
  B Ruiter, HA Sampson, WG Shreffler, 2010 AAAAI Annual Meeting, New Orleans, LA, 1/1/2010
• Further characterization of putative basophil nanotubes by confocal microscopy
  A Praslick, M Masilimani, M Gross, WG Shreffler, 2010 AAAAI Annual Meeting, New Orleans, LA, 1/1/2010
• Literature review abstracts
  Shreffler WG, Pediatrics, 1/1/2005
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Lectures

• Identifying and Developing Great Mentors and Great Projects 
  San Antonio, TX - 1/1/2013
• Future Directions in Food Allergen Immunotherapy 
  San Antonio, TX - 1/1/2013
• Update on Food Allergy and Immunotherapy / Therapeutic Vaccines: Reprogramming Immunity in Infectious Diseases, Allergy and Cancer 
  Annecy, France - 1/1/2013
• Food Allergy and Immunotherapy 
  Milan, Italy - 1/1/2013
• Dendritic cells in sickness and in health; arbiters of allergy versus tolerance 
  San Fransisco, CA - 1/1/2013
• Anaphylaxis and food allergy in the pediatric population 
  Boston MA - 1/1/2012
• Mechanisms of Activation and Desensitisation Underlying Spontaneous Tolerance in Food Allergy 
  Geneva, Switzerland - 1/1/2012
• Update on Food Allergy 
  Boston MA - 1/1/2012
• Summary of the NIAID Food Allergy Guidelines 
  Boston MA - 1/1/2012
• Eosinophilic Esophagitis and its Relation to Food Allergy 
  Marlborough MA - 1/1/2012
• Implementing Peanut Oral Immunotherapy 
  Boston MA - 1/1/2012
• Guidelines for the Diagnosis and Management of Food Allergy 
  Lowell MA - 1/1/2012
• Overview of food allergies in pediatrics 
  Boston MA - 1/1/2012
• Eosinophilic GI Disease, Brigham and Women’s Hospital Board Review Course 
  Boston, MA - 1/1/2012
• Mechanisms of OIT-induced Tolerance in the Setting of Food Allergy; Immuno- inflammation Therapeutic Strategy Unit 
  Bridgewater, NJ - 1/1/2012
• The Role of Humoral Immunity in Food Allergy/ Allergy & Immunology Seminar Series 
  Boston, MA - 1/1/2012
• Update on Food Allergy and the Use of Molecular Allergen Testing 
  Berkeley, CA - 1/1/2012
• Cellular Assays for Monitoring Allergen Immunotherapy 
  Orlando, FL - 1/1/2012
• Dissecting Mechanisms of Oral Tolerance in Food Allergy 
  Orlando, FL - 1/1/2012
• Patient handout sheets on: Food Allergies; Treatment of Anaphylaxis; Eosinophilic Esophagitis; Allergen Avoidance 
  1/1/2011
• TSLP/DC Polarization to TH2 Response 
  Aspen, CO - 1/1/2011
• Asthma Educator’s Course, Understanding Allergy in Asthma 
  Boston, MA - 1/1/2011
• Determinants of Oral Tolerance versus Mucosal Allergy 
  Charlottesville, VA - 1/1/2011
• FADDA Interest Section Forum: Can IgE/IgG4 Food Epitopes Help Predict the Clinical Severity of Milk and Peanut Allergy? 
  San Francisco, CA - 1/1/2011
• Evaluating mechanisms of allergic disease in humans: basophils 
  Boston MA - 1/1/2011
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Other

• Future diagnostic tools for food allergy 
  Shreffler WG, Andreae DA
  http://www.uptodate.com/contents/future-diagnostic-tools-for-food-allergy
  UpToDate, Wolters Kluwer Health - 2013-04-18
• OpenWetWare 
  Shreffler WG
  http://openwetware.org/index.php?title=Shreffler&oldid=312635