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Office
1 Barnes Jewish Hospital Plz
Saint Louis, MO 63110Phone+1 800-862-9980Fax+1 314-362-1185
Summary
- My laboratory studies the structural mechanisms of ion channel gating and pharmacology. We use cryo-EM, photolabeling, mass spectrometry, electrophysiology and MD simulations.
Education & Training
- Washington University/B-JH/SLCH ConsortiumFellowship, Adult Cardiothoracic Anesthesiology, 2016 - 2017
- Washington University/B-JH/SLCH ConsortiumResidency, Anesthesiology, 2012 - 2016
- Washington University in St. Louis School of MedicineClass of 2012
Certifications & Licensure
- MO State Medical License 2015 - 2025
- American Board of Anesthesiology Anesthesiology
Publications & Presentations
PubMed
- 10 citationsLipid nanodisc scaffold and size alter the structure of a pentameric ligand-gated ion channel.Vikram Dalal, Mark J Arcario, John T Petroff 2nd, Brandon K Tan, Noah M Dietzen
Nature Communications. 2024-01-02 - 15 citationsOpen-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.John T Petroff 2nd, Noah M Dietzen, Ezry Santiago-McRae, Brett Deng, Maya S Washington
Nature Communications. 2022-11-17 - 44 citationsA phase 2 trial of inhaled nitrous oxide for treatment-resistant major depressionPeter Nagele, Ben J.A. Palanca, Britt M. Gott, Frank Brown, Linda D. Barnes
Science Translational Medicine. 2021-06-09
Press Mentions
- 5 Physician-Scientists Named Dean’s Scholars – Washington University School of Medicine in St. LouisJune 22nd, 2023
Grant Support
- Lipid Modulation of Ligand-Gated Ion ChannelsNIH2020–2025
- CHARACTERIZING NEUROSTEROID BINDING IN THE GABA(A) RECEPTOR USING TOP-DOWN MASS SPECTROMETRYNIH2017–2020
- Pilot and feasibilityCIMED2017–2019
Committees
- Member, T32 Training Program Executive Advisory Committee 2018 - Present
External Links
- Labhttp://wchenglab.org
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