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Office
800 Spruce St
# Rs
Philadelphia, PA 19107Phone+1 215-829-3000Fax+1 215-829-7564
Education & Training
- MIT & Rockefeller UniversityPost-Doctoral Fellowship, 1991 - 1996
- Brigham and Women's HospitalResidency, Pathology-Anatomic and Clinical, 1989 - 1991
- University of Rochester School of Medicine and DentistryClass of 1989, MD
- Karolinska InstitutePhD, Tumor Biology, 1983 - 1987
- Williams CollegeBA, Economics, 1976 - 1980
Certifications & Licensure
- PA State Medical License 1996 - 2024
- American Board of Pathology Clinical Pathology
Awards, Honors, & Recognition
- Elected Member Association of American Physicians (AAP), 2002
- Elected Member American Society of Clinical Investigation (ASCI)
Publications & Presentations
PubMed
- 138 citationsNotch signalling in T‐cell lymphoblastic leukaemia/lymphoma and other haematological malignanciesJon C. Aster, Stephen C. Blacklow, Warren S. Pear
The Journal of Pathology. 2011-01-01 - 149 citationsDistinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1Bas J. Wouters, Meritxell Alberich Jordà, Karen Keeshan, Irene Louwers, Claudia A.J. Erpelinck-Verschueren
Blood. 2007-11-15 - 73 citationsT cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1.Maria Elena De Obaldia, J. Jeremiah Bell, Xinxin Wang, Christelle Harly, Yumi Yashiro-Ohtani
Nature Immunology. 2013-12-01
Journal Articles
- Downregulating Notch Counteracts KrasG12D-Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative NeoplasmErik A Ranheim, David Yang, Warren S Pear, Lan Zhou, Mignon Loh, Eric Padron, Elliot Stieglitz, Nature
Press Mentions
- Systemic Notch Downregulation Promotes KrasG12D‐Induced Myeloproliferative NeoplasmMarch 31st, 2019
- Linking Mutations in Notch Gene to Role in B-cell CancersNovember 25th, 2017
- Newly Described Type of Immune Cell and T Cells Share Similar Path to MaturityMay 14th, 2013
Grant Support
- Immunobiology Of Normal And Neoplastic LymphocytesNational Cancer Institute2010–2012
- The Function Of Tribbles In The Pathogenesis Of AMLNational Cancer Institute2007–2011
- Retroviral Transduction CoreNational Cancer Institute2007–2011
- Oncogenic Notch Signaling: Mouse ModelingNational Cancer Institute2006–2010
- Notch Regulation Of Hematopoetic Cell FatesNational Institute Of Allergy And Infectious Diseases2000–2010
- Pathogenesis Of Chronic Myelogenous LeukemiaNational Cancer Institute1999–2003
- Signals Downstream Of Notch Regulating Lymphoid Cell Fate And FunctionNational Cancer Institute2002
- Notch Signaling In B Cell Development And SurvivalNational Cancer Institute2002
- Core--Retroviral Transduction Of Murine Bone Marrow For In Vivo AnalysisNational Cancer Institute2002
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