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Office
800 Spruce St
# Rs
Philadelphia, PA 19107Phone+1 215-829-3000Fax+1 215-829-7564
Education & Training
- MIT & Rockefeller UniversityPost-Doctoral Fellowship, 1991 - 1996
- Brigham and Women's HospitalResidency, Pathology-Anatomic and Clinical, 1989 - 1991
- University of Rochester School of Medicine and DentistryClass of 1989, MD
- Karolinska InstitutePhD, Tumor Biology, 1983 - 1987
- Williams CollegeBA, Economics, 1976 - 1980
Certifications & Licensure
- PA State Medical License 1996 - 2024
- American Board of Pathology Clinical Pathology
Awards, Honors, & Recognition
- Elected Member Association of American Physicians (AAP), 2002
- Elected Member American Society of Clinical Investigation (ASCI)
Publications & Presentations
PubMed
- 563 citationsExclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.Warren S. Pear, Jon C. Aster, Martin L. Scott, Robert P. Hasserjian, Benny Soffer
The Journal of Experimental Medicine. 1996-05-01 - 453 citationsThe Varied Roles of Notch in CancerJon C. Aster, Warren S. Pear, Stephen C. Blacklow
Annual Review of Pathology. 2017-01-30 - 241 citationsThe multifaceted role of Notch in cancer.Monideepa Roy, Warren S. Pear, Jon C. Aster
Current Opinion in Genetics & Development. 2007-02-01
Journal Articles
- Downregulating Notch Counteracts KrasG12D-Induced ERK Activation and Oxidative Phosphorylation in Myeloproliferative NeoplasmErik A Ranheim, David Yang, Warren S Pear, Lan Zhou, Mignon Loh, Eric Padron, Elliot Stieglitz, Nature
Press Mentions
- Systemic Notch Downregulation Promotes KrasG12D‐Induced Myeloproliferative NeoplasmMarch 31st, 2019
- Linking Mutations in Notch Gene to Role in B-cell CancersNovember 25th, 2017
- Newly Described Type of Immune Cell and T Cells Share Similar Path to MaturityMay 14th, 2013
Grant Support
- Immunobiology Of Normal And Neoplastic LymphocytesNational Cancer Institute2010–2012
- The Function Of Tribbles In The Pathogenesis Of AMLNational Cancer Institute2007–2011
- Retroviral Transduction CoreNational Cancer Institute2007–2011
- Oncogenic Notch Signaling: Mouse ModelingNational Cancer Institute2006–2010
- Notch Regulation Of Hematopoetic Cell FatesNational Institute Of Allergy And Infectious Diseases2000–2010
- Pathogenesis Of Chronic Myelogenous LeukemiaNational Cancer Institute1999–2003
- Signals Downstream Of Notch Regulating Lymphoid Cell Fate And FunctionNational Cancer Institute2002
- Notch Signaling In B Cell Development And SurvivalNational Cancer Institute2002
- Core--Retroviral Transduction Of Murine Bone Marrow For In Vivo AnalysisNational Cancer Institute2002
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