VincentCrynsMD
Endocrinology • Madison, WIDiabetes, Osteoporosis & Bone Metabolism Medicine, Parathyroid, Thyroid
Professor of Medicine; Marian A. and Rodney P. Burgenske Chair; Chief, Division of Endocrinology, Diabetes and Metabolism, University of Wisconsin School of Medicine and Public Health
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Office
451 Junction Rd
Madison, WI 53717Phone+1 608-263-5010Fax+1 608-263-9983
Summary
- Dr. Cryns is Professor of Medicine and Chief of the Division of Endocrinology, Diabetes and Metabolism at the University of Wisconsin-Madison School of Medicine and Public Health. He leads a multidisciplinary team of scientists who focus on understanding how cells die. His group is especially interested in elucidating how abnormalities in cell death contribute to the pathogenesis of cancer and other diseases and in translating these insights into improved biomarkers and pro-apoptotic therapies.
Education & Training
Massachusetts General HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 1990 - 1993
Dartmouth-Hitchcock/Mary Hitchcock Memorial HospitalResidency, Internal Medicine, 1988 - 1990- Massachusetts General HospitalInternship, Internal Medicine, 1987 - 1988
Harvard Medical SchoolClass of 1987
Certifications & Licensure
WI State Medical License 2011 - 2025
IL State Medical License 1997 - 2014- American Board of Internal Medicine Endocrinology, Diabetes and Metabolism
Awards, Honors, & Recognition
- Best Doctors in America 2013-2014
- Elected Member American Society for Clinical Investigation (ASCI), 2005
Clinical Trials
- A Window of Opportunity Study of Methionine Deprivation in Triple Negative Breast Cancer Start of enrollment: 2017 Aug 10
- ONC201 With a Methionine-Restricted Diet in Patients With Metastatic Triple Negative Breast Cancer Start of enrollment: 2018 Nov 13
Publications & Presentations
PubMed
- 653 citationsCaspase cleavage of tau: Linking amyloid and neurofibrillary tangles in Alzheimer's diseaseT. Chris Gamblin, Feng Chen, Angara Zambrano, Aida Abraha, Sarita Lagalwar
Proceedings of the National Academy of Sciences of the United States of America. 2003-08-19 - 29 citationsProteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosisFeng Chen, Onur Karamanoglu Arseven, Vincent L. Cryns
The Journal of Biological Chemistry. 2004-06-25 - 173 citationsEarly N-Terminal Changes and Caspase-6 Cleavage of Tau in Alzheimer's DiseasePeleg M. Horowitz, Kristina R. Patterson, Angela L. Guillozet-Bongaarts, Matthew R. Reynolds, Christopher A. Carroll
The Journal of Neuroscience. 2004-09-08
Press Mentions
UW Madison Scientists Discover Cancer Pathway BreakthroughApril 5th, 2019
Unlocking a Secret of the Anti-Cancer Gene p53March 18th, 2019
UW-Madison Scientists Make Key Discovery on Protein That's a Major Focus of Cancer ResearchMarch 18th, 2019- Join now to see all
External Links
- Cryns labhttp://crynslab.medicine.wisc.edu/
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