VimalKumarDerebailMDMPH FASN

Nephrology • Chapel Hill, NC

Glomerular Disease

Associate Professor of Medicine University of North Carolina at Chapel Hill School of Medicine

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Office
7024 Burnett Womack Campus
# 7155
Chapel Hill, NC 27599
Phone+1 919-966-2561

Fax+1 919-966-4251

Education & Training

University of North Carolina HospitalsFellowship, Research Fellow in Nephrology, 2009 - 2011
University of North Carolina at Chapel Hill, Gillings School of Global Public HealthMPH, Epidemiology, 2007 - 2010
University of North Carolina HospitalsFellowship, Nephrology, 2006 - 2009
University of North Carolina HospitalsResidency, Internal Medicine, 2002 - 2005
Medical College of Georgia at Augusta UniversityClass of 2002, MD
Duke UniversityBS, Biology / Religion, 1993 - 1997

Certifications & Licensure

NC State Medical License 2002 - 2025
SC State Medical License 2021 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Nephrology

Clinical Trials

Acthar for Treatment of Proteinuria in Membranous Nephropathy Patients Start of enrollment: 2011 Aug 01
Completed
Phase 4
Randomized, Double-Blind, Safety and Efficacy Study of RE-021 (Sparsentan) in Focal Segmental Glomerulosclerosis Start of enrollment: 2014 Mar 01
Completed
Phase 2
Lipid Lowering Agents to Limit Lipid Oxidation and Activation of Clotting System in Nephrotic Syndrome Start of enrollment: 2012 May 01
Completed
Phase 1
Efficacy and Safety of Tolvaptan in Subjects With Chronic Kidney Disease Between Late Stage 2 to Early Stage 4 Due to Autosomal Dominant Polycystic Kidney Disease Start of enrollment: 2014 May 01
Completed
Phase 3
Pharmacokinetics of Apixaban in Nephrotic Syndrome Start of enrollment: 2017 Apr 30
Completed
Phase 1
Trial to Evaluate Anticoagulation Therapy in Hemodialysis Patients With Atrial Fibrillation Start of enrollment: 2016 Dec 01
Completed
Phase 4
A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis Start of enrollment: 2017 Mar 15
Completed
Phase 3
Kidney Function in Sickle Cell Anemia Start of enrollment: 2017 Nov 17
Active, not recruiting
Study to Evaluate the Safety and Efficacy of Filgotinib and Lanraplenib in Adults With Lupus Membranous Nephropathy (LMN) Start of enrollment: 2017 Oct 06
Completed
Phase 2
Study of Sparsentan in Patients With Primary Focal Segmental Glomerulosclerosis (FSGS) Start of enrollment: 2018 Apr 17
Active, not recruiting
Phase 3
Safety and Efficacy Study of IFX-1 in add-on to Standard of Care in GPA and MPA Start of enrollment: 2018 Oct 15
Terminated
Phase 2
ADPKD Alterations in Hepatic Transporter Function Start of enrollment: 2018 Sep 17
Completed
Tailoring Maintenance Therapy to Cluster of Differentiation 5 Positive (CD5+) Regulatory B Cell Recovery in ANCA Vasculitis Start of enrollment: 2019 Jun 28
Suspended
Not Applicable
Belimumab With Rituximab for Primary Membranous Nephropathy Start of enrollment: 2020 Mar 06
Active, not recruiting
Phase 2
A Study With Imlifidase in Anti-GBM Disease Start of enrollment: 2022 Dec 22
Recruiting
Phase 3
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Publications & Presentations

PubMed

Emergency department intravenous fluid resuscitation and renal outcomes among adults with sickle cell disease.
Marcus A Carden, Jeffrey Lebensburger, Wayne Rosamond, Paula Tanabe, Vimal K Derebail
American Journal of Hematology. 2025-01-01
Association of biomarkers of endothelial function, coagulation activation and kidney injury with persistent albuminuria in sickle cell anaemia.
Laila Elsherif, Yihan Tang, Kammie L Patillo, David Wichlan, Ugochi O Ogu
British Journal of Haematology. 2024-11-01
Anticoagulation for the Prevention of Thrombotic Events in Nephrotic Syndrome.
David Massicotte Azarniouch, Daniel J Crona, Priscilla Karnabi, Bhadran Bose, Patrick H Nachman
Kidney International Reports. 2024-10-01

Journal Articles

Effect of Renin‐Angiotensin‐Aldosterone System Blocking Agents on Progression of Glomerulopathy in Sickle Cell Disease
Vimal K Derebail, Kenneth I Ataga, British Journal of Haematology
DUET: A Phase 2 Study Evaluating the Efficacy and Safety of Sparsentan in Patients with FSGS
Howard Trachtman, Peter Nelson, Abanti Chaudhuri, Jai Radhakrishnan, Olga Zhdanova, Debbie S Gipson, Tarak Srivastava, Kenneth Lieberman, Vimal Kumar Derebail, Jonatha..., Journal of the American Society of Nephrology

Abstracts/Posters

The Effect of Crizanlizumab Plus Standard of Care (SoC) Versus Soc Alone on Renal Function in Patients with Sickle Cell Disease and Chronic Kidney Disease: A Randomize...
Vimal K. Derebail, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Opioid Analgesics Are Associated with Albuminuria in Adult Patients with Sickle Cell Anemia
Vimal K. Derebail, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Manifestations of Reduced Kidney Function Occur at a Higher Estimated Glomerular Filtration Rate in Sickle Cell Anemia
Vimal K. Derebail, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Manifestations of Reduced Kidney Function Occur at a Higher Estimated Glomerular Filtration Rate in Sickle Cell Anemia
Vimal K. Derebail, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
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Lectures

Association of Sickle Cell Trait with Measures of Cognitive Function and Dementia in African Americans
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Rapid Decline in Kidney Function in Sickle Cell Disease
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018

Press Mentions

Sickle Cell Trait Is Not Risk Factor for Kidney Disease: Study Contradicts Earlier FindingsSeptember 14th, 2011
Sickle Cell Trait in African-American Dialysis Patients Affects Dosing of Anemia DrugsFebruary 10th, 2016