Dr. Thannickal is on Doximity
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Office
1430 Tulane Avenue
New Orleans, LA 70112Phone+1 504-988-7800
Summary
- Dr. Thannickal is Professor of Medicine and the Harry B. Greenberg Chair, Department of Medicine at Tulane University School of Medicine. Dr. Thannickal’s research is focused on cellular and molecular mechanisms of lung repair and regeneration. This work has advanced fundamental understanding of myofibroblast origins, differentiation, and survival in pulmonary fibrosis. The clinical impact of his work is evidenced by current and emerging anti-fibrotic therapies in pre-clinical/clinical development; this includes inhibitors of FAK/Akt, MRTF-A/ROCK and NADPH oxidase-4 (NOX4). His laboratory was the first to identify an essential role for NOX4 in organ fibrosis and has elucidated mechanisms by which redox imbalance and metabolic alterations contribute to age-dependent susceptibility to fibrosis. Active studies are focused on elucidating mechanisms of cellular senescence, oxidative stress, and aging in the context of chronic lung diseases, in concert with the development of therapeutics and biomarkers for complex lung diseases. His research program is funded by the National Institutes of Health and the U.S. Department of Veterans Affairs.
Dr. Thannickal is an elected member of American Association of Physicians, and received the American Thoracic Society (ATS) Recognition Award for Scientific Accomplishments in 2016. He currently serves on the Editorial Boards of the Journal of Clinical Investigation (Consulting Editor), as well those of the American Journal of Respiratory and Critical Care Medicine and the American Journal of Pathology; he is an Associate Editor of the American Journal of Respiratory Cell and Molecular Biology.
Education & Training
- Tufts Medical CenterFellowship, Pulmonary Disease and Critical Care Medicine, 1991 - 1993
- University of Oklahoma School of Community Medicine (Tulsa)Residency, Internal Medicine, 1989 - 1990
- City of Faith HospitalResidency, Internal Medicine, 1987 - 1989
- Oral Roberts University School of MedicineClass of 1987
Certifications & Licensure
- LA State Medical License 2020 - 2025
- AL State Medical License 2009 - 2020
- FL State Medical License 2013 - 2015
- MI State Medical License 2002 - 2012
- OK State Medical License 1988 - 1992
- American Board of Internal Medicine Critical Care Medicine
- American Board of Internal Medicine Pulmonary Disease
Awards, Honors, & Recognition
- Regional Top Doctor Castle Connolly, 2014
Publications & Presentations
PubMed
- 1 citationsEndoplasmic Reticulum Oxidative Stress Promotes Glutathione-Dependent Oxidation of Collagen-1A1 and Promotes Lung Fibroblast Activation.Joseph E Druso, Maximilian B MacPherson, Shi B Chia, Evan Elko, Reem Aboushousha
American Journal of Respiratory Cell and Molecular Biology. 2024-11-01 - Heavy Metal Exposure-Mediated Dysregulation of Sphingolipid Metabolism.Shaheer Ahmad, Sierra Single, Yuelong Liu, Kenneth P Hough, Yong Wang
Antioxidants. 2024-08-12 - Lipids to the Rescue in Pulmonary Fibrosis: Biosynthesis, Bioenergetics, or Epigenetics?Manas Ranjan Gartia, Victor J Thannickal
American Journal of Respiratory Cell and Molecular Biology. 2024-08-01
Journal Articles
- Myofibroblast Functions in Tissue Repair and Fibrosis: An IntroductionThannickal VJ, Methods Mol Biol
- Extracellular Vesicle Mediated Tumor-Stromal Crosstalk Within an Engineered Lung Cancer ModelGoliwas KF, Ashraf HM, Wood AM, Wang Y, Hough KP, Bodduluri S, Athar M, Berry JL, Ponnazhagan S, Thannickal VJ, Deshane JS, Front Oncol
- Divergent Regulation of Alveolar Type 2 Cell and Fibroblast Apoptosis by Plasminogen Activator Inhibitor 1 in Lung FibrosisJiang C, Liu G, Cai L, Deshane J, Antony V, Thannickal VJ, Liu RM, Am J Pathol
Press Mentions
- Genkyotex Provides New Clinical Data from the PBC Phase 2 Trial Providing Further Evidence of the Anti-Fibrotic Activity of SetanaxibJune 18th, 2020
- Phase 2 Trial of Oral Setanaxib in IPF Patients Expected to Open SoonApril 28th, 2020
- Experimental Fibrosis Drug May Help Immuno-Oncology TherapiesMarch 9th, 2020
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Grant Support
- Rho-Kinase Pathway In Pulmonary FibrosisNational Heart, Lung, And Blood Institute2011–2012
- Training Program In Lung Biology And Translational MedicineNational Heart, Lung, And Blood Institute2010–2011
- Oxidants And Tgf-Beta In Myofibroblast Differentiation/SurvivalNational Heart, Lung, And Blood Institute2009–2011
- Mass Spectrometry-Based Biomarker DiscoveryNational Heart, Lung, And Blood Institute2009–2011
- Oxidants And Tgf-Beta In Myofibroblast Differentiation/SurvivalNational Heart, Lung, And Blood Institute2008
- Alveolar Mesenchymal Cells In Acute Lung InjuryNational Heart, Lung, And Blood Institute2003–2007
- Oxidants And Tgf-Beta In Myofibroblast DifferentiationNational Heart, Lung, And Blood Institute2001–2004
- Oxidants And Tgf-Beta In Myofibroblast DifferentiationNational Heart, Lung, And Blood Institute2001
- Reactive Oxygen Species As Mediators Of Tgf-B1 ActionsNational Heart, Lung, And Blood Institute1996–2000
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