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Office
263 Farmington Ave
Farmington, CT 06030Phone+1 860-679-2100Fax+1 860-679-4815
Education & Training
- Johns Hopkins UniversityFellowship, Hematology and Medical Oncology, 2000 - 2002
- Johns Hopkins UniversityFellowship, Hematology and Medical Oncology, 1999 - 2000
- George Washington UniversityResidency, Internal Medicine, 1996 - 1999
- University of Zimbabwe Huggins SOMClass of 1991
Certifications & Licensure
- PA State Medical License 2008 - 2014
Clinical Trials
- Trial of Exemestane +/- MM-121 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive and/or Progesterone Receptor Positive Her2 Negative Breast Cancer Start of enrollment: 2010 Jun 01
- Safety and Pharmacokinetic Study of MM-302 in Patients With Advanced Breast Cancer Start of enrollment: 2011 Mar 01
Publications & Presentations
PubMed
- 15 citationsPhase 1 Dose Escalation Study of Seribantumab (MM-121), an anti-HER3 Monoclonal Antibody, in Patients with Advanced Solid TumorsCrystal S. Denlinger, Vicki L. Keedy, Victor Moyo, Gavin MacBeath, Geoffrey I. Shapiro
Investigational New Drugs. 2021-07-11 - 9 citationsLiposomal encapsulation of trans-crocetin enhances oxygenation in patients with COVID-19-related ARDS receiving mechanical ventilation.Paul-Michel Mertes, Olivier Collange, Pierre Coliat, Mainak Banerjee, Marie-Charlotte Diringer
Journal of Controlled Release. 2021-06-24 - 62 citationsSafety and pharmacokinetics of MM-302, a HER2-targeted antibody-liposomal doxorubicin conjugate, in patients with advanced HER2-positive breast cancer: a phase 1 dose-...Pamela N. Munster, Ian E. Krop, Patricia LoRusso, Cynthia X. Ma, Barry A. Siegel
British Journal of Cancer. 2018-10-26
Press Mentions
- L.E.A.F. Pharmaceuticals Lead Investigational Product for Lung and Colorectal Cancers, LEAF-1401, Featured at the 2020 Virtual Annual Meeting of the American Society of Clinical Oncology (ASCO)June 10th, 2020
- L.E.A.F. Pharmaceuticals Receives Positive US FDA Feedback and Comprehensive Roadmap for Clinical Development as Well as Registration of Its Four Lead Novel Anticancer DrugsOctober 30th, 2018
Grant Support
- Antigenics Renal CarcinomaNational Center For Research Resources2004
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