VenkateswaraVinodMoothaMD

PubMed

• 3 citations
  Loss of Corneal Nerves and Corneal Haze in Patients with Fuchs' Endothelial Corneal Dystrophy with the Transcription Factor 4 Gene Trinucleotide Repeat Expansion.
  Matthew Gillings, Andrew Mastro, Xunzhi Zhang, Kelly Kiser, Jane Gu
  Ophthalmology Science. 2023-03-01
• 5 citations
  Update on the genetics of corneal endothelial dystrophies.
  Chitra Kannabiran, Sunita Chaurasia, Muralidhar Ramappa, Venkateswara Vinod Mootha
  Indian Journal of Ophthalmology. 2022-07-01
• 8 citations
  A novel homozygous missense mutation p.P388S in TULP1 causes protein instability and retinitis pigmentosa.
  DaNae R Woodard, Chao Xing, Pratyusha Ganne, Hanquan Liang, Avinash Mahindrakar
  Molecular Vision. 2021-04-02

Journal Articles

• Instability of TCF4 Triplet Repeat Expansion with Parent–Child Transmission in Fuchs' Endothelial Corneal Dystrophy  
  Joanna S Saade, V Vinod Mootha, Investigative Ophthalmology and Visual Science
• Oligonucleotides Targeting TCF4 Triplet Repeat Expansion Inhibit RNA Foci and Mis-splicing in Fuchs' Dystrophy  
  Hu J, Rong Z, Gong X, Zhou Z, Sharma VK, Xing C, Watts JK, Corey DR,�Mootha VV, Hum Mol Genet, 1/8/2018
• Instability of TCF4 Triplet Repeat Expansion With Parent-Child Transmission in Fuchs' Endothelial Corneal Dystrophy  
  Saade JS, Xing C, Gong X, Zhou Z, Mootha VV, Invest Ophthalmol Vis Sci, 1/1/2018
• Genome-wide association study identifies three novel loci in Fuchs endothelial corneal dystrophy  
  Afshari NA, Igo RP Jr, Morris NJ, Stambolian D, Sharma S, Pulagam VL, Dunn S, Stamler JF, Truitt BJ, Rimmler J, Kuot A, Croasdale CR, Qin X, Burdon KP, Riazuddin SA, M..., Nat Commun, 1/30/2017
• Fuchs' Endothelial Corneal Dystrophy and RNA Foci in Patients With Myotonic Dystrophy  
  Mootha�VV, Hansen B, Rong Z, Mammen PP, Zhou Z, Xing C, Gong X, Invest Ophthalmol Vis Sci, 1/1/2017
• Exome Sequencing Reveals Novel Homozygous FOXE3 Mutation in Microphthalmos with Staphylomatous Malformation  
  Saboo US, Penke D Mahindrakar A, Uddaraju M, Sankurathri C, Gong X Xing C, Mootha VV, Ophthalmic Genetics, 1/1/2017
• A novel H395R mutation in MKKS/BBS6 causes retinitis pigmentosa and polydactyly without other findings of Bardet-Biedl or McKusick-Kaufman syndrome  
  Hulleman JD, Nguyen A, Ramprasad VL, Murugan S, Gupta R, Mahindrakar A, Angara R, Sankurathri C, Mootha VV, Mol Vision, 1/24/2016
• TCF4 Triplet Repeat Expansion and Nuclear RNA Foci in Fuchs' Endothelial Corneal Dystrophy  
  Mootha VV, Hussain I, Cunnusamy K, Graham E, Gong X, Neelam S, Kittler R, Xing C, Petroll M, Invest Ophthalmol Vis Sci, 1/26/2015
• Correlation of Severity of Fuchs' Endothelial Corneal Dystrophy with Triplet Repeat Expansion in TCF4  
  Soliman AS, Xing C, Radwan SH, Gong X, Mootha VV, JAMA Opththal, 1/24/2015
• Blunt Scissors Dissection technique for Deep Anterior Lamellar Keratoplasty-reply to Letter to Editor  
  Mootha VV, Anwar D, Kruger M, Clinical Ophthalmology, 1/1/2015
• Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) Tissue Insertion Devices: A Review  
  Khan S, Shiakolas P, Mootha VV, Journal of Ophthalmic and Vision Research, 1/1/2015
• Blunt Scissors Dissection technique for Deep Anterior Lamellar Keratoplasty  
  Anwar D, Kruger M, Mootha VV, Clinical Ophthalmology, 1/15/2014
• Association and Familial Segregation of CTG181 trinucleotide repeat expansion of TCF4 Gene in Fuchs' endothelial Corneal Dystrophy  
  Mootha VV, Gong X, Ku H-C, Xing C, Invest Ophthalmol Vis Sci, 1/1/2014
• A Novel De Novo KIF21A Mutation in a patient with Congenital Fibrosis of the Extraocular Muscles, and Mobius Syndrome  
  Ali Z, Xing C, Anwar D, Itani K, Weakley D, Gong X, Pascual JM, Mootha VV, Molecular Vision, 1/1/2014
• Trans-ethnic Replication of Association of CTG181 Repeat Expansion of TCF4 Gene with Fuchs' Corneal Dystrophy  
  Xing C, Gong X, Hussain I, Khor CC, Tan DT, Aung T, Mehta JS, Vithana EN,�Mootha VV, Invest Ophthalmol Vis Sci, 1/1/2014
• Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error  
  Mootha VV and the Fuchs' Genetics Multi-center Study Group, Cheng CY, Schache M, Ikram MK, Young TL, Guggenheim JA, Vitart V, MacGregor S, Verhoeven VJ, Barathi VA, Li..., Am J Hum Genet, 1/8/2013
• Association of Smoking and Other Risk Factors with Fuchs' Endothelial Corneal Dystrophy Severity and Corneal Thickness  
  Zhang X, Igo, Jr, RP, Fondran J, Mootha VV, Oliva M, Hammersmith K, Sugar A, Lass JH, Iyengar SK for the Fuchs' Genetics Multi-Center Study Group, Invest Ophthalmol Vis Sci, 1/1/2013
• Genome-wide meta-analyses of multi-ancestry cohorts identify multiple new susceptibility loci for refractive error and myopia  
  Mootha VV and the Fuchs' Genetics Multi-center Study Group, Verhoeven VJ, Hysi PG, Wojciechowski R, Fan Q, Guggenheim JA, Höhn R, MacGregor S, Hewitt AW, Nag A, Cheng ..., Nat Genet, 1/1/2013
• Features of Urrets-Zavalia Syndrome Following Descemet after Descemet Stripping Automated Endothelial Keratoplasty  
  Anwar DS, Chu CY, Prasher P, Dai E, Bowman RW, Mootha VV, Cornea, 1/1/2012
• Relationship Between Fuchs' Endothelial Corneal Dystrophy Severity and Glaucoma and or Ocular Hypertension  
  Mootha VV and the Fuchs' Genetics Multi-center Study Group, Nagarsheth M, Singh A, Schmotzer B, Babineau DC, Sugar J, et al, Archives of Ophthalmology, 1/1/2012
• Differing Roles for TCF4 and COL8A2 in Central Corneal Thickness and Fuchs Endothelial Corneal Dystrophy  
  Mootha VV and the Fuchs' Genetics Multi-center Study Group, Igo RP Jr., Kopplin, LJ, Joseph P, et al, PLOS One, 1/1/2012
• Identification problems with Sterile Fungi, illustrated by a Keratitis due to a Non-Sporulating Chaetomium-like species  
  Mootha VV, Shahinpoor P, Sutton DA, Xin L, Najafzadeh MJ, De Hoog GS, Med Mycol, 1/1/2012
• Relationship of Fuchs Endothelial Corneal Dystrophy Severity to Central Corneal Thickness  
  Mootha VV and the Fuchs' Genetics Multi-center Study Group Kopplin LJ, Przepyszny K, Schmotzer B, et al, Archives of Ophthalmology, 1/1/2012
• A multi-center study to map genes for Fuchs' Endothelial Corneal Dystrophy: Baseline Characteristics and Heritability  
  Mootha VV and the Fuchs' Genetics Multi-center Study Group, Louttit MD, Kopplin LJ, Igo RP Jr, Fondran JR, Tagliaferri A, Bardenstein D, Aldave AJ, Croasdale CR, Price..., Cornea, 1/1/2012
• Glaucoma in patients with Corneal Endothelial Dystrophy  
  Ali ZK, Whitson JT, Mootha VV, Witherspoon SR, Joseph JA, Joseph AM, Hynan LS, Cavanagh HD, Eye Contact Lens, 1/1/2011
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Books/Book Chapters

• Principles and Practice of Ophthalmology 
  Chapter: Ocular Genetics 
  Hansen B, Mootha V.V.Editors: Venkatesh Prajna.Jaypee Brothers2018
• Advances in Vision Research: Volume 1, Genetic Eye Research In Asia and the Pacific, Essentials in Ophthalmology 
  Chapter: Genetics of Corneal Endothelial Dystrophies: An Asian Perspective 
  Neelam S, Mehta J.S., Vithana E. N., Mootha V. V.Editors: Gyan Prakash & Takeshi Iwata.Springer2016

Abstracts/Posters

• Triplet repeat primed PCR assay to genotype the CTG18.1 trinucleotide repeat polymorphism in TCF4.
  Imran Hussain, Xin Gong�and Vinod V. Mootha, Association for Research in Vision and Ophthalmology Annual Meeting, Orlando, FL, 1/4/2014
• CTG18.1 Trinucleotide Repeat Expansion of TCF4 Gene in Fuchs' Endothelial Corneal Dystrophy.
  Ahmed Z. Soliman, Xin Gong, Imran Hussain, Chao Xing�and Vinod V. Mootha, Association for Research in Vision and Ophthalmology Annual Meeting, Orlando, FL, 1/4/2014
• Novel CHRLD1 Mutation and Secondary Glaucoma in Patient with X-Linked Megalocornea.
  X, Whitson, J, Mootha VV, Association for Research in Vision and Ophthalmology Annual Meeting, Seattle, WA, 1/8/2013
• Ocular Manifestations of X-linked Reticulate Pigmentary Disorder.
  Dajee K, Mootha VV, Association for Research in Vision and Ophthalmology Annual Meeting, Seattle, WA, 1/8/2013
• Impact of Donor Age of Endothelium-Descemet Membrane Layer Harvesting and Roll Formation.
  Bennett A, Mootha VV, Association for Research in Vision and Ophthalmology Annual Meeting, Seattle, WA, 1/6/2013
• Supervised resident manual small incision cataract surgery (MSICS) outcomes at Parkland Hospital.
  Lynds R, Hansen B, Mootha VV, University of Texas Southwestern Medical Center, Annual Resident and Alumni Day, 1/1/2013
• Corneal Biomechanics and the Ocular Response Analyzer Waveform in the Preoperative Evaluation of Keratorefractive Surgery Patients.
  Mootha VV, Patel CG, Bowman RW, Verity S, McCulley JP, Texas Medical Association, Austin, TX, 1/18/2012
• Polymorphic Amyloid Degeneration: Slit Lamp Findings and Advanced Imaging Results.
  Lubahn J, Mootha VV, McCulley JP, Bowman RW, University of Texas Southwestern Medical Center, Annual Resident and Alumni Day, 1/16/2012
• Anterior Segment Dysgenesis in a Family with Monozygotic Twins.
  Mootha VV, Gong X, Guenena G, Whitson JW, Cavanagh D, Association for Research in Vision and Ophthalmology Annual Meeting, Ft. Lauderdale, FL, 1/1/2012
• Histopathology and OCT Findings of Big Bubble Deep Anterior Lamellar Keratoplasty.
  Kim SY, Muftuoglu O, Hogan RN, Mootha VV, University of Texas, Southwestern Medical Center, Annual Resident and Alumni Day, 1/18/2011
• Corneal Biomechanics and their Role in the Preoperative Evaluation of Refractive Surgery Patients.
  Mootha VV, Patel Chirag, University of Texas, Southwestern Medical Center, Annual Resident and Alumni Day, 1/18/2011
• Sporadic Case of Congenital Fibrosis of the Extraocular Muscles.
  Mootha VV, Ali ZK, Association for Research in Vision and Ophthalmology Annual Meeting, Ft. Lauderdale, FL, 1/1/2011
• Phenotypic Variability in Hereditary Benign Intraepithelial Dyskeratosis In a Unique Family From Texas.
  Mootha VV, Lubahn JG, Association for Research in Vision and Ophthalmology Annual Meeting, Ft. Lauderdale, FL, 1/1/2011
• A Unique Family with Hereditary Benign Intraepithelial Dyskeratosis: Phenotypic and Genotypic Results.
  Lubahn J, Mootha VV, University of Texas, Southwestern Medical Center, Annual Resident and Alumni Day, 1/26/2010
• Retrospective Review of Outcomes in Manual Small Incision Cataract Surgery.
  Posvar B, Mootha VV, University of Texas, Southwestern Medical Center, Annual Resident and Alumni Day, 1/26/2010
• Correlation of Big-Bubble DALK with OCT and Histopathology in Donor Corneas.
  Kim SY, Mootha VV, Hogan RN, University of Texas, Southwestern Medical Center, Annual Resident and Alumni Day, 1/26/2010
• Histopathology and OCT Findings of Big Bubble Deep Anterior Lamellar Keratoplasty.
  Kim SY, Muftuoglu O, Hogan RN, Mootha VV, The American Academy of Ophthalmology Annual Meeting, Chicago, IL, 1/17/2010
• The Prevalence of POAG in Corneal Endothelial Dystrophy.
  Ali Z, Whitson J, Mootha VV, Witherspoon SR, Joseph A, Hyman L, Cavanagh D, The Cornea Society/EBAA (Eye Bank Association of America) Fall Educational Symposium, Chicago, IL, 1/15/2010
• Mutational Spectrum of Fuchs' Endothelial Corneal Dystrophy.
  Mootha VV, Osamah S, McCulley JP, Xing C, Chandrasekhar S, International Symposium on Role of Genomics in Clinical Practice & 35th Annual Conference, Indian Society of Human Genetics, 1/7/2010
• Intraocular Pressure, Corneal and Anterior Chamber Changes After Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK).
  Di Pascuale MA, Pessach Y, Mootha VV, Association for Research in Vision and Ophthalmology Annual Meeting, Ft. Lauderdale, FL, 1/5/2010
• Incidence of Intraocular Pressure Evaluation and Risk Factors for Glaucoma Following Descemet Stripping Endothelial Keratoplasty.
  Allen, M, Aggarwal, N, Mootha VV, University of Texas Southwestern Medical Center, Annual Resident and Alumni Day, 1/20/2009
• Factors Affecting Visual Outcome in Deep Anterior Lamellar Keratoplasty.
  Di Pascuale MA, Mootha VV, University of Texas Southwestern Medical Center, Annual Resident and Alumni Day, 1/20/2009
• Prevalence of Inherited Eye Disease in Godavari Districts in Andhra Pradesh, India.
  Osamah S, Mootha VV, University of Texas Southwestern Medical Center, Annual Resident and Alumni Day, 1/20/2009
• Outcomes of Limbal Relaxing Incisions with Apodized Diffractive Multifocal IOL Implantation.
  Chu CY, Muftuoglu O, Verity SM, Mootha VV, Cavanagh HD, McCulley JP, Bowman RW, ASCRS (American Society of Cataract and Refractive Surgery) Symposium on Cataract, IOL and Refractive Surgery, San Francisco, CA, 1/1/2009
• Evaluation of Zonal Equivalent Keratometry Readings After LASIK.
  Koover T, Muftuoglu O, Mootha VV, Verity SM, Bowman RW, Cavanagh HD, McCulley JP, ASCRS (American Society of Cataract and Refractive Surgery) Symposium on Cataract, IOL and Refractive Surgery, San Francisco, CA, 1/1/2009
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Lectures

• Window on Molecular Pathogenesis of Fuchs' Endothelial Corneal Dystrophy 
  1/11/2018
• Future of Fuchs' Dystrophy 
  1/5/2018
• TCF4 Triplet repeat Expansion in Fuch's Endothelial Corneal Dystrophy: An Ideal Oligonucleotide Therapeutic Target for a Common Human Disease 
  Cold Spring Harbor, NY - 1/30/2017
• Corneal Dystrophies: Anterior, Stromal & Endothelial 
  Kakinada, India - 1/19/2017
• Fuchs' Endothelial Corneal Dystrophy: Developments in Molecular Genetics and Surgery 
  Madurai, India - 1/1/2017
• Intergenerational Stability of CTG18.1 Triplet Repeat Locus in Fuchs' Endothelial Corneal Dystrophy 
  1/19/2016
• Molecular Genetic Basis of Fuchs' Endothelial Corneal Dystrophy: Focus on the Foci 
  1/30/2015
• Management of Dry Eye in Autoimmune Disease 
  University of Texas Southwestern Medical Center - 1/25/2015
• Fuchs' Endothelial Corneal Dystrophy: Focus on the Foci 
  1/16/2015
• Update on Lamellar Keratoplasty 
  Austin, TX - 1/1/2015
• Genetic Eye Disease in Rural India 
  1/29/2014
• Fuchs' Endothelial Corneal Dystrophy: A Common Triplet Repeat Expansion Disorder 
  1/26/2014
• Genetic Basis of Eye Disease in a Rural Endogamous Population in India 
  1/7/2014
• Genetic Architecture of Fuchs' Endothelial Corneal Dystrophy 
  1/5/2013
• Update in Cataract Surgery 
  Kakinada, India - 1/3/2013
• Factors Impacting BSCVA after Descemet Stripping Automated Endothelial Keratoplasty 
  1/18/2012
• Anterior Segment Dysgenesis 
  1/11/2012
• Update On The Genetics of Fuchs' Endothelial Corneal Dystrophy 
  1/15/2011
• Genetics and Genomics of Corneal Disorders 
  1/6/2011
• Ophthalmology International Outreach 
  1/3/2011
• "Extracapsular Cataract Extraction: Non-phacoemulsification Large-and Small-Incision Approach" 
  Chicago, IL - 1/17/2010
• Ocular Chemical Injuries: Diagnosis and Management 
  University of Texas Southwestern Medical Center - 1/7/2010
• Mutational Spectrum of Anterior Segment Ophthalmic Disorders 
  1/6/2010
• Ophthalmic Mission Outreach 
  University of Texas Southwestern Medical Center - 1/4/2010
• Genetics of Fuchs' Dystrophy 
  McDermott Center for Human Genetics, University of Texas Southwestern Medical Center - 1/30/2009
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Other

• "No Femto Fix for PK Trauma" 
  Mootha VV, News is Review (by Linda Roach), EyeNet, pp. 15-16
  1/1/2012
• "Microkeratomes Yield Smoother Stromal Bed Than Femtosecond Laser in DSAEK Prep" 
  Mootha VV, Ocular Surgery News (by Matt Hasson), pp. 25-26
  1/10/2011
• The Ogawa Technique for Trans-Scleral Sutured PCIOL Placement 
  M.A. Di Pascuale, V.V. Mootha, G.S.H. Ogawa, ASCRA/ASOA (American Society of Cataract and Refractive Surgery/American Society of Ophthalmic Admin
  1/28/2007
• "Get Those Kids Into The Shades" 
  Mootha VV, Dallas Morning News (by Michael Precker), E1-2
  1/9/2005
• "LASIK May Hurt Donor Corneas" 
  Mootha VV, Albuquerque Journal (by Jackie Jadrnak), C1-2
  1/21/2004
• "UNM Researchers Announce Corneal Wound Healing Findings after LASIK Surgery" 
  Mootha VV, University of New Mexico Health Sciences News Release on UNM HSC Web Site (by Cindy Foster)
  1/20/2004
• Conjunctival Ulceration associated with Primary Herpes Simplex Virus Blepharoconjunctivitis. 
  Shahinpoor P, Wood M, Overturf G, Mootha VV, Morning Rounds: "A Small Angel with a most Peculiar Finding." EyeNet, pp. 39-40
  1/1/2004
• "Beyond the American Dream: Exchange Program Opens Eyes for a Developing Nation: Physician Volunteers Encouraged to Offer Eye Care to South India's Impoverished" 
  Mootha VV, Ophthalmology Times (by Ann Bergstrom), pp. 54-55
  1/15/2002
• "When the Student Becomes the Teacher" 
  Mootha VV, 2002 Annual Report: A Retrospective (by Elizabeth Koenig), University of Wisconsin Department of Oph
  1/1/2002
• "LASIK Surgery" 
  Mootha VV, Interview on Eyewitness News, KOBTV Channel 4, New Mexico NBC Affiliate
  1/20/2001
• "Cataract Surgery Informed Consent" 
  Mootha VV, Patient Video (produced by James Janis), New Mexico VA Healthcare System
  1/1/2001
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