Tyler Eugene Miller MD PhD

Summary

• Dr. Miller is the Paul and Betsy Shiverick Professor of Immuno-Oncology and a physician-scientist at Case Western Reserve University School of Medicine and University Hospitals in Cleveland, OH. As a practicing pathologist and researcher, his work focuses on developing novel immunotherapy strategies for solid tumors, with a particular emphasis on brain cancers. Clinically, Dr. Miller is a Molecular Pathologist in the Genomic and Molecular Pathology at University Hospitals. Dr. Miller also leads a translational research lab that integrates advanced single-cell genomics, spatial transcriptomics and proteomics, and patient-derived tumor organoid modeling to better understand and target the immunosuppressive myeloid cells that contribute to immunotherapy resistance. His work has uncovered fundamental mechanisms of myeloid-driven immunosuppression in glioblastoma, paving the way for more effective immunotherapeutic approaches. Learn more at tymillerlab.org