TrentEdwardTippleMDFAAP

PubMed

• 45 citations
  Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygen.
  Lynette K. Rogers, Trent E. Tipple, Leif D. Nelin, Stephen E. Welty
  Pediatric Research. 2009-01-01
• 17 citations
  Thioredoxin Reductase-1 Inhibition Augments Endogenous Glutathione-Dependent Antioxidant Responses in Experimental Bronchopulmonary Dysplasia.
  Stephanie B. Wall, Rachael Wood, Katelyn Dunigan, Qian Li, Rui Li
  Oxidative Medicine and Cellular Longevity. 2019-01-21
• 32 citations
  The thioredoxin reductase-1 inhibitor aurothioglucose attenuates lung injury and improves survival in a murine model of acute respiratory distress syndrome.
  Rodney D. Britt, Markus Velten, Morgan L. Locy, Lynette K. Rogers, Trent E. Tipple
  Antioxidants & Redox Signaling. 2014-06-10

Journal Articles

• microRNA-17~92 Cluster Expression is Significantly Attenuated in Bronchopulmonary Dysplasia  
  Rogers LK, Robbins M, Dukhlallah D, Yang Z, Lee LJ, Mikhail M, Nuovo G, Pryhuber GS, McGwin G, Marsh CB, AnnalsATS, 1/1/2015
• DHA Suppresses Chronic Apoptosis in the Lung Caused by Perinatal Inflammation  
  Ali M, Heyob KM, Velten M, Rogers, LK, American Journal of Physiology: Lung Cellular and Molecular Physiology, 1/1/2015
• The Thioredoxin System in Neonatal Lung Disease  
  Tipple TE, Antioxidants and Redox Signaling, 1/1/2014
• Arginase II is a Target of miR-17-5p and Regulates miR-17-5p Expression in Human Pulmonary Artery Smooth Muscle Cells  
  Jin Y, Jin Y, Chen B, Nelin LD, American Journal of Physiology: Lung Cellular and Molecular Physiology, 1/1/2014
• The Thioredoxin Reductase-1 Inhibitor Aurothioglucose Attenuates Lung Injury and Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome  
  Britt RD, Velten M, Locy ML, Rogers LK, Antioxidants and Redox Signaling, 1/1/2014
• Maternal Dietary Docosahexaenoic Acid (DHA) Supplementation Prevents Fetal Growth Restriction and Pulmonary Injury in a Newborn Murine Model of Perinatal Inflammation  
  Velten M, Britt RD, Heyob KM, Rogers LK, Journal of Nutrition, 1/1/2014
• Neonatal Hyperoxic Exposure Persistently Alters Lung Secretoglobin and Annexin Expression  
  Raffay TM, Locy ML, Hill CL, Rogers LK, Welty SE, Biomedical Research International, 1/1/2013
• Thioredoxin-1 Mediates Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation  
  Chen B, Nelin VE, Locy ML, Jin Y, American Journal of Physiology: Lung Cellular and Molecular Physiology, 1/1/2013
• Cyclooxygenase-2 in Newborn Hyperoxic Lung Injury  
  Britt RD, Velten M, Nelin LD, Rogers LK, Free Radical Biology and Medicine, 1/1/2013
• Thioredoxin Reductase Inhibition Elicits Nrf2-mediated Responses in Clara Cells: Implications for Oxidant-induced Lung Injury  
  Locy ML, Rogers LK, Prigge JR, Schmidt EE, Arnér ESJ, Antioxidants and Redox Signaling, 1/1/2012
• Perinatal Inflammation and Neonatal Oxygen Contributes to an Emphysematous and Fibrotic Lung Phenotype in Adult Mice  
  Velten M, Britt RD, Heyob KM, Welty SE, Rogers LK, American Journal of Physiology: Regulatory Integrative and Comparative Physiology, 1/1/2012
• Plasma Lipid Metabolites are Associated with Gestational Age but Not Bronchopulmonary Dysplasia  
  Rogers LK, Young CM, Pennell ML, Leonhart KL, Welty SE, Acta Paediatrica, 1/1/2012
• Lipopolysaccharide-induced Cyclooxygenase-2 Expression in Mouse Transformed Clara Cells  
  Britt RD, Locy ML, Nelin LD, Rogers LK, Cellular Physiology and Biochemistry, 1/1/2012
• Riboflavin Supplementation Does Not Attenuate Hyperoxic Lung Injury in Transgenic spc-mt hGR Mice  
  Heyob KM, Rogers LK, Welty SE, Experimental Lung Research, 1/1/2011
• Maternal DHA Supplementation Decreases Lung Inflammation in Hyperoxia-Exposed Newborn Mice  
  Rogers LK, Valentine CJ, Pennell M, Velten M, Britt RD, Dingess K, Zhao X, Welty SE, Journal of Nutrition, 1/1/2011
• Thioredoxin Interacting Protein Inhibits Hypoxia-Inducible Factor Transcriptional Activity  
  Farrell MR, Rogers LK, Lu Y, Welty SE, Free Radical Biology and Medicine, 1/1/2010
• Hyperoxia Exposure Alters Hepatic Lipid Metabolism in Newborn Mice  
  Rogers LK, Britt RD, Welty SE, Pediatric Research, 1/1/2010
• Alterations of the Lung Thioredoxin System By Hyperoxia: Implications for Alveolarization  
  Welty SE, Nelin LD, Hansen JM, Rogers LK, American Journal of Respiratory Cell and Molecular Biology, 1/1/2009
• Differential Response in the Lungs of Newborn Mouse Pups Exposed to 85% or >95% Oxygen  
  Rogers LK, Nelin LD, and Welty SE, Pediatric Research, 1/1/2009
• Thioredoxin Related Mechanisms in Hyperoxic Lung Injury in Mice  
  Welty SE, Rogers LK, Hansen TN, Choi YE, Kehrer JP, Smith CV, American Journal of Respiratory Cell and Molecular Biology, 1/1/2007
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Books/Book Chapters

• Reference Module in Biomedical Sciences 
  Chapter: Mechanisms: Free Radicals and Reactive Oxygen Species 
  Kehrer JP, Robertson JD, Smith CVEditors: Michael Caplan.Elsevier2014
• Methods in Molecular Biology – Developmental Toxicology 
  Chapter: Methods for the Determination of Plasma or Tissue Glutathione Levels 
  Page 315 - 324Tipple TE, Rogers LKEditors: Craig Harris and Jason Hansen.Humana Press, London2012
• General Principles, Toxicokinetics, and Mechanisms of Toxicity 
  Chapter: Mechanisms: Free Radicals and Reactive Oxygen Species 
  Page 277 - 307Kehrer JP, Robertson JD, Smith CVEditors: J.A. Bond.Elsevier2010

Abstracts/Posters

• Decreased Plasma miR-17~92 Cluster Expression in the First Week of Life Correlates with a Subsequent Diagnosis of Bronchopulmonary Dysplasia
  Yang Z, Lee LJ, McGwin G, Rogers LK, American Journal of Respiratory and Critical Care Medicine, 1/1/2015
• Thioredoxin Reductase Inhibition Attenuates Hyperoxia-induced Lung Developmental Deficits in Newborn Mice
  Hill CL, Pierce DL, Velten M, Rogers LK, American Journal of Respiratory and Critical Care Medicine, 1/1/2014
• Haplotype-Insufficiency of miR-17~92 Cluster Alters Lung Development in Newborn Mice
  Robbins ME, Rogers LK, Piper MG, Pediatric Academic Societies, 1/1/2014
• Aurothioglucose Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome
  Britt RD, Rogers LK, Pediatric Academic Societies, 1/1/2013
• Aurothioglucose Improves Alveolarization in a Newborn Mouse Model of Bronchopulmonary Dysplasia
  Moyer S, Pierce D, Hill CL, Rogers LK, Free Radical Biology and Medicine, 1/1/2013
• miR-17~92 Cluster Expression Is Decreased In Bronchopulmonary Dysplasia
  Robbins M, Dakhlallah D, Rogers LK, Piper MG, American Journal of Respiratory and Critical Care Medicine, 1/1/2013
• Aurothioglucose Enhances Glutathione Levels And Improves Survival In A Murine Model Of Acute Respiratory Distress Syndrome
  Britt RD, Locy ML, Velten M, Rogers LK, American Journal of Respiratory and Critical Care Medicine, 1/1/2013
• Maternal Dietary Docosahexaenoic acid (DHA) Supplementation Prevents Fetal Growth Restriction and Pulmonary Fibrosis Caused by Perinatal Inflammation
  Britt RD, Heyob KM, Rogers LK, FASEB Journal, 1/1/2013
• Robbins ME, Rogers LK, Piper MG, Pediatric Academic Societies, 1/1/2013
• miR-17~92 Cluster Expression Is Decreased in Lungs from Infants with Bronchopulmonary Dysplasia
  Robbins M, Rogers LK, Dakhlallah D, Piper MG, Pediatric Academic Societies, 1/1/2013
• Pharmacological Inhibition of Thioredoxin Reductase-1 Attenuates Hyperoxic Lung Injury by Augmenting Glutathione Synthesis
  Rogers LK, Britt RD, Velten M, The Toxicologist, 1/1/2013
• Perinatal Inflammation and Decreases in miR29b-1 Expression are Associated with Structural and Functional Pulmonary Deficits in Adult Mice
  Velten M, Heyob KM, Welty SE, Rogers LK, FASEB Journal, 1/1/2012
• Aurothioglucose Enhances Lung Glutathione Levels and Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome
  Britt RD, Locy ML, Rogers LK, Free Radical Biology and Medicine, 1/1/2012
• Inhibition of Cox-2 Decreases Macrophage Infiltration in Newborn Hyperoxic Lung Injury
  Rogers LK, Velten M, Britt RD, Free Radical Biology and Medicine, 1/1/2012
• Pam2CSK, a TLR2 agonist, Increases Chemokine Expression in Mouse Transformed Clara Cells
  Britt RD, Locy ML, Rogers LK, American Journal of Respiratory and Critical Care Medicine, 1/1/2012
• Oxidized Intracellular Glutathione Redox State in Neonatal Mice Persistently Alters Alveolar Epithelial Composition
  Robbins ME, Locy ML, Hill CL, Hansen JM, Rogers LK, Pediatric Academic Societies, 1/1/2012
• Perinatal Inflammation Negatively Impacts Lung Structure and Function in Adult Mice
  Velten M, Britt RD, Heyob KM, Rogers LK, American Journal of Respiratory and Critical Care Medicine, 1/1/2012
• Maternal DHA Supplementation Improves Lung Growth and Function in Offspring Exposed to LPS and Hyperoxia
  Velten M, Heyob KM, Britt RD, Valentine CJ, Rogers LK, FASEB Journal, 1/1/2012
• Neonatal Inflammation Contributes to Fibrotic Lung Disease in Adult Mice
  Rogers LK, Britt RD, Heyob KM, Velten M, The Toxicologist, 1/1/2012
• Thioredoxin-1 Mediates Hypoxia induced Pulmonary Artery Smooth Muscle Cell Proliferation
  Nelin V, Gin Y, Rogers LK, Nelin LD, FASEB Journal, 1/1/2012
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Lectures

• Targeting Thioredoxin Reductase to Prevent Oxygen-Induced Lung Injury 
  University of Alabama at Birmingham - 1/1/2015
• Thioredoxin Reductase Inhibition to Prevent Lung Injury: Interplay With Cadmium and Selenium 
  Emory University, Atlanta, GA - 1/1/2015
• Thioredoxin Reductase: A Novel Therapeutic Target to Prevent Oxidant Lung Injury 
  Sanford Research Institute, Sioux Falls, SD - 1/1/2015
• Decreased Plasma miR-17~92 Cluster Expression in the First Week of Life Correlates with a Subsequent Diagnosis of Bronchopulmonary Dysplasia 
  Denver, CO - 1/1/2015
• Thioredoxin Reductase Inhibition Attenuates Hyperoxia-induced Lung Developmental Deficits in Newborn Mice 
  San Diego, CA - 1/1/2014
• Novel Strategies to Improve Outcomes in Infants With Bronchopulmonary Dysplasia 
  Nationwide Children’s Hospital - 1/1/2014
• Reflections on a Blessed Existence 
  Columbus, OH - 1/1/2014
• Physician + Scientist: The Good News is You Can Do Both 
  Butler University, Indianapolis, IN - 1/1/2014
• An Antioxidant Paradox: Inhibition of Thioredoxin Reductase to Prevent Pulmonary Disease 
  National Institute of Environmental Health Sciences, Research Triangle Park, NC, 2014; University of - 1/1/2014
• Serendipity: When the Fellowship Project You Tried to Forget Comes Full Circle 
  The Research Institute at Nationwide Children’s Hospital - 1/1/2013
• Aurothioglucose Enhances Glutathione Levels and Improves Survival in a Murine Model of Acute Respiratory Distress Syndrome 
  Philadelphia, PA - 1/1/2013
• miR-17~92 Cluster is Decreased in Lungs from Infants With Bronchopulmonary Dysplasia 
  Washington, DC - 1/1/2013
• Aurothioglucose Improves Alveolarization in a Murine Model of Bronchopulmonary Dysplasia 
  San Antonio, TX - 1/1/2013
• An Antioxidant Paradox: Inhibition of Thioredoxin Reductase to Prevent Bronchopulmonary Dysplasia 
  Chicago, IL - 1/1/2013
• miR-17~92 Cluster Expression is Decreased in Bronchopulmonary Dysplasia 
  1/1/2013
• Respiratory Distress in the Newborn 
  1/1/2013
• Thioredoxin-1 Modulates Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation 
  Atlanta, GA - 1/1/2011
• Many Moments of Gratitude 
  Columbus, OH - 1/1/2011
• Respiratory Distress Syndrome 
  1/1/2010
• Thioredoxin Interacting Protein-Dependent Regulation of VEGF-Mediated Lung Development 
  1/1/2010
• The Jaundiced Newborn 
  1/1/2010
• Overexpression of Thioredoxin Interacting Protein Decreases Hypoxia Response Element Promoter Activity in Murine Alveolar Cells 
  San Francisco, CA - 1/1/2009
• Alterations of the Thioredoxin System by Hyperoxia: Implications for Alveolar Development 
  Houston, TX - 1/1/2008
• Oxygen Toxicity: Basic Mechanisms and Biochemistry 
  1/1/2008
• Pulmonary VEGF and Thioredoxin Interacting Protein Levels are Inversely Correlated in a Neonatal Mouse Model of BPD 
  Honolulu, HI - 1/1/2008
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