Dr. Downs is on Doximity
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Office
500 Ray C Hunt Dr
Charlottesville, VA 22903Phone+1 434-924-2224Fax+1 434-244-9481
Summary
- Dr. Downs is certified by the American Board of Urology. He specializes in the surgical treatment of urologic cancers and treats all forms of urologic cancers including bladder cancer, prostate cancer, kidney cancer, testis cancer and penile cancer. He has a special interest in the treatment of bladder cancer, where he performs robotic cystectomy (da Vinci robotic system), along with complex urinary reconstruction to make a new internalized bladder (orthotopic neobladder). Dr. Downs’ clinical care philosophy is to provide compassionate, cutting-edge urologic cancer care to his patients.
Research Interests
Dr. Downs has a joint appointment with the UW Carbone Cancer Center, and his clinical research emphasizes developing new therapies for genitourinary cancers.
Research Focus
Chemoprevention – Bladder cancer, prostate cancer
Screening Programs – Bladder cancer screening for high-risk subjects
Outcomes Research – Patient outcomes of treatments for non-muscle invasive (superficial) bladder cancer and radical cystectomy
Translational Research – Discovery of molecular and urinary biomarkers (bladder cancer)
Quality of Life Outcomes – Bladder cancer, prostate cancer
Education & Training
- University of California (San Francisco)Fellowship, Minimally Invasive Urologic Surgery, 2001 - 2003
- Brigham and Women's Hospital/Harvard Medical SchoolResidency, Urology, 1995 - 2001
- Brigham and Women's HospitalResidency, Surgery, 1993 - 1995
- University of California San Diego School of MedicineClass of 1993
Certifications & Licensure
- CA State Medical License 2001 - Present
- VA State Medical License 2021 - 2026
- WI State Medical License 2010 - 2023
- MA State Medical License 1999 - 2008
- American Board of Urology Urology
Awards, Honors, & Recognition
- Regional Top Doctor Castle Connolly, 2014
- Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2012
- Fellow (FACS) American College of Surgeons
Clinical Trials
- Green Tea Extract in Treating Patients With Nonmetastatic Bladder Cancer Start of enrollment: 2008 Jul 02
- Pomegranate-Extract Pill in Preventing Tumor Growth in Patients With Localized Prostate Cancer Undergoing Active Surveillance Start of enrollment: 2014 May 08
- Erlotinib Hydrochloride in Treating Patients With Bladder Cancer Undergoing Surgery Start of enrollment: 2014 Oct 01
Publications & Presentations
PubMed
- 59 citationsTwo-dimensional transcriptome profiling: identification of messenger RNA isoform signatures in prostate cancer from archived paraffin-embedded cancer specimens.Hairi Li, Jessica Wang-Rodriguez, T. Murlidharan Nair, Joanne M. Yeakley, Young-Soo Kwon
Cancer Research. 2006-04-15 - 79 citationsExpression signatures that correlated with Gleason score and relapse in prostate cancer.Marina Bibikova, Eugene Chudin, Amir Arsanjani, Lixin Zhou, Eliza Wickham Garcia
Genomics. 2007-06-01 - 26 citationsPursuing Quality in the Application of Bladder Cancer Quality of Life Research.Nihal Mohamed, F. Gilbert, Cheryl T. Lee, John P. Sfakianos, Cynthia J. Knauer
Bladder Cancer. 2016-04-27
Press Mentions
- UVA Health Hires Chief Diversity & Community Engagement OfficersApril 12th, 2021
- Better Models Needed for Predicting Bladder Ca RecurrenceOctober 11th, 2017
- Q&A: Brian Gittens' Diversity MissionApril 10th, 2017
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