TimothyCRykenMDMS, FACS, FAANS

PubMed

• 657 citations
  A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine Oncology Study Group.
  Charles G. Fisher, Christian P. DiPaola, Timothy C. Ryken, Mark H. Bilsky, Christopher I. Shaffrey
  Spine. 2010-10-15
• 329 citations
  Spinal Instability Neoplastic Score: An Analysis of Reliability and Validity From the Spine Oncology Study Group
  Daryl R. Fourney, Evan Frangou, Timothy C. Ryken, Christian P. DiPaola, Christopher I. Shaffrey
  Journal of Clinical Oncology. 2011-08-01
• 38 citations
  Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Treatment of Adults With Metastatic Brain Tumors: Executive Summary
  Jeffrey J. Olson, Steven N. Kalkanis, Timothy C. Ryken
  Neurosurgery. 2019-03-01

Journal Articles

• CD271+ Cells Are Diagnostic and Prognostic and Exhibit Elevated MAPK Activity in SHH Medulloblastoma  
  Timothy Ryken, MD, Clinical Cancer Research
• Suppression of glioma growth in vitro and in vivo by glia maturation factor.  
  Lim R, Hicklin DJ, Ryken TC, Han X, Kang-Nian L, Miller JF, Baggenstoss BA, Cancer Research 46(10):5241-5247
• Endogenous immunoreactive glia maturation factor-like molecule in astrocytes and glioma cells.  
  Lim R, Hicklin DJ, Ryken TC, Miller JF, Brain Research 430(1):49-57
• Ultrastructure of Endothelium Invitro – Analysis of Differences in Vascular Bed, Species, and Culture Conditions.  
  Turner JW, Sandra A, Ryken T, Bar R, J of Electron Microscopy Techniques
• Induction of cytoskeletal alterations in C6 glioma by glia maturation factor.  
  Ryken TC, Turner JW, Hicklin DJ, Miller JF, Baggenstoss BA, Lim R, International Journal of Developmental Neuroscience 5(3):215-225
• Extreme haircutting and psychosis.  
  Strawn K, Ryken TC, Black D, American Journal of Psychiatry 144(8):1102-3
• Endogenous immunoreactive glia maturation factor-like molecule in cultured rat Schwann cells.  
  Lim R, Hicklin DJ, Ryken TC, Miller JF, Bosch EP, Brain Research 468(2):277-284
• Haloperidol-induced neuroleptic malignant syndrome in a 67 year old woman with parkinsonism.  
  Ryken TC, Merrell AN, Western Journal of Medicine 151:326-328
• Amoxicillin overdose with gross hematuria.  
  Bright DA, Gaupp FB, Becker LJ, Schiffert MG, Ryken TC, Western Journal of Medicine 150(6):698-699
• Stigmatophilia.  
  Ryken TC, Henderson ST, Merrell AN, Medical Aspects of Human Sexuality
• Bilateral testicular torsion in a preterm neonate.  
  Ryken TC, Turner JW, Haynes T, Journal of Urology 143:102-103
• Haircutting and psychosis revisited.  
  Ryken TC, Merrell AN, Journal of Clinical Psychiatry 51(2):83
• Interaction of acidic fibroblast growth factor and transforming growth factor-beta in normal and transformed glia in vitro.  
  Ryken TC, Traynelis VC, Lim R, Journal of Neurosurgery 76(5):850-855
• Craniovertebral abnormalities in Down’s syndrome.  
  Menezes AH, Ryken TC, Pediatric Neurosurgery 18(1):24-33
• Interaction of acidic fibroblast growth factor and transforming growth factor-beta in cultured endothelium.  
  Ryken TC, Traynelis VC, Surgical Forum 43:535-537
• Botulinum toxin in cervical immobilization.  
  Traynelis VC, Ryken TC, Rodnitzky RL, Menezes AH, Journal of Neurosurgery 77(5):808-809
• Infratentorial stereotactic biopsy: a review of eleven cases.  
  Ryken TC, Hitchon PW, Roach RM, Traynelis VC, Stereotactic and Functional Neurosurgery 59:111-114
• Investigation of lipid metabolism in normal glia using a fluorescent ceramide probe.  
  Ryken TC, Traynelis VC, Sandra A, Surgical Forum 44:562-564
• Morphological and ultrastructural analysis of C6 glioma in vitro.  
  Gerdes JS, Ryken TC, Traynelis VC, Surgical Forum 44:560-562
• Non-rheumatoid cranial settling.  
  Ryken TC, Menezes AH, Spine 18(16):2525-2527
• Craniovertebral abnormalities in Down’s syndrome.  
  Menezes AH, Ryken TC, Pediatric Neurosurgery 19(4):224
• Cervicomedullary compression by separate atlantal lateral mass.  
  Ryken TC, Menezes AH, Pediatric Neurosurg 19(3):165-8
• Cervicomedullary compression in achondroplasia.  
  Ryken TC, Menezes AH, Journal of Neurosurgery 81:43-48
• Familial occurrence in subependymoma.  
  Ryken TC, Robinson R, VanGilder JC, Journal of Neurosurgery 80:1108-1111
• Subependymoma in siblings.  
  Ryken TC, Robinson R, VanGilder JC, Journal of Neurosurgery, 81(6):961-962
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Books/Book Chapters

• The Year Book of Diagnostic Radiology. 
  Chapter: Cervicomedullary compression in achondroplasia 
  Ryken TC, Menezes AHEditors: Young L.Mosby, Chicago
• Evidence Based Neurosurgery. 
  Chapter: Neuro-Oncology: The Role of Surgery in the Management of Malignant Glioma 
  Page 37 - 104Ryken TC, Frankel B, Bernstein MEditors: Stephen J Haines and Beverly C. Walters.Thieme
• Handbook of Clinical Neuropsychology. 
  Chapter: Intracranial Tumors 
  Anderson S, Ryken TCEditors: Morgan and Ricker.Swets & Zeitlinger
• Cancer of the Central Nervous System. 
  Chapter: The Role of Fractionated Conformal Radiotherapy in the Treatment of Pituitary Tumors 
  Page 439 - 444Buatti JM, Meeks SL, Ryken TCEditors: Peter McL. Black and Jay S. Loeffler.Lipincott Williams and Wilkins, Philadelphia, PAEdition 2,
• Textbook of Neuro-Oncology. 
  Chapter: Intracerebral Metastatic Colon Carcinoma 
  Page 443 - 450Ryken TC, Carlisle T, Buatti JEditors: Mitchel S. Berger and Michael D Prados.Elseview Saunders
• Biomechanics of Osteoporotic Bone. 
  Chapter: Osteoporosis in interbody Fusion 
  Ferrar L, Ryken TCEditors: An H.Springer-Verlag
• Biomechanics of Bone Testing. 
  Chapter: Screw pullout testing 
  Ferrara L, Ryken TCEditors: An H.Springer-Verlag
• The Pediatric Spine: Principles and Practice. 
  Chapter: Craniovertebral junction abnormalities in the pediatric spine 
  Page 219 - 237Menezes AH, Ryken TCEditors: Weinstein SL.Lippincott Williams & Wilkins, Philadelphia
• Pediatric Neurosurgery: Surgery of the Developing Nervous System 
  Chapter: Abnormalities of the craniocervical junction 
  Page 400 - 422Menezes AH, Ryken TC, Brockmeyer DLEditors: McLone DG.WB Saunders Company, Orlando, FloridaEdition 4,
• Infections of the Central Nervous System: Diagnosis and Management. 
  Chapter: Atypical bacterial infections: actinomycosis and nocardiosis 
  Soults CB, Ryken TCEditors: Osenbach R, Zeidman S.Lippincott-Raven, Philadelphia
• Principles of Neurosurgery. 
  Chapter: Evaluation, management and surgical repair of cervical spinal column trauma 
  Page 183 - 196Traynelis VC, Ryken TCEditors: Grossman R, Loftus C.Lippincott-Raven, Philadelphia
• Principles of Neurosurgery. 
  Chapter: Intraspinal hemorrhage from idiopathic or structural causes 
  Page 627 - 638Watts CW, Ryken TCEditors: Grossman R, Loftus C.Lippincott-Raven, Philadelphia
• Neurosurgical Operative Atlas. Vol. 2 
  Chapter: Surgical management of anterior communicating artery aneurysms 
  Page 273 - 281Ryken TC, Loftus CMEditors: Wilkins R.Williams and Wilkins, Baltimore, MDEdition 4,
• The Year Book of Neuroradiology. 
  Chapter: Cervicomedullary compression in achondroplasia 
  Ryken TC, Menezes AHEditors: Ross JS.Mosby, Chicago
• Neurosurgical Complication of Pregnancy (AANS Neurosurgical Topics) 
  Chapter: Pseudotumor cerebri, hydrocephalus and ventriculoperitoneal shunts in pregnancy 
  Page 165 - 176Ryken TCEditors: Loftus CM.Williams and Wilkins, Baltimore, MD
• Principles of Spinal Surgery. Vol 1. 
  Chapter: Abnormalities of the craniovertebral junction in Down’s syndrome 
  Page 395 - 409Ryken TC, Menezes AHEditors: Menezes AH, Sonntag VK.McGraw-Hill, New York
• Pediatric Neurosurgery. 
  Chapter: Abnormalities of the craniocervical junction 
  Page 139 - 158Menezes AH, Ryken TCEditors: Cheek WR.WB Saunders, PhiladelphiaEdition 3,
• Spinal Fusion and Stabilization. 
  Chapter: Biomechanics of the cervical spine 
  Page 38 - 50Goel VJ, Clausen JD, Ryken TC, Traynelis VCEditors: Hitchon PW, Rengachery S, Traynelis VC.Thieme Medical Publishers, New York
• Spinal Fusion and Stabilization. 
  Chapter: Anterior bicortical plate stabilization of the cervical spine 
  Page 170 - 175Traynelis VC, Ryken TCEditors: Hitchon PW, Rengachery S, Traynelis VC.Thieme Medical Publishers, New York
• Spinal Instrumentation (AANS Neurosurgical Topics). Vol 2 
  Chapter: Instrumentation of the craniocervical region 
  Page 47 - 62Menezes AH, Ryken TCEditors: Benzel EC.Williams and Wilkins, Baltimore, MD
• Neurosurgical Emergencies (AANS Neurosurgical Topics). Vol. 1 
  Chapter: Acute bony decompression of the optic and facial nerves 
  Page 195 - 216Ryken TC, Traynelis VCEditors: Loftus CM.Williams and Wilkins, Baltimore, MD
• Pediatric Spine: Principles and Practice. Vol. 1 
  Chapter: Craniovertebral junction abnormalities in the pediatric spine 
  Page 307 - 321Menezes AH, Ryken TCEditors: Weinstein SL.Raven Press, New York
• Intraoperative Monitoring Techniques in Neurosurgery. 
  Chapter: Intraoperative electrical and manometric monitoring techniques in lumbosacral surgery 
  Page 257 - 268Ryken TC, Menezes AHEditors: Loftus CM, Traynelis VC.McGraw-Hill, New York
• Neurosurgical Operative Atlas. Vol 3 
  Chapter: Surgical Management of Cerebral Abscess 
  Page 449 - 457Ryken TC, Loftus CMEditors: Wilkins R.William and Wilkins, Baltimore, MDEdition 6,
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Abstracts/Posters

• Infratentorial stereotactic biopsy.
  Ryken TC, Hitchon PW, Roach RM, Traynelis VC, Iowa Midwest Neurosurgical Society Semi-Annual Meeting, Omaha, NE
• Stereotactic approach to brain stem lesions.
  Ryken TC, Hitchon PW, University of Iowa Department of Surgery Residents and Fellows Research Day, Iowa City, IA
• Cervical lipomas.
  Ryken TC, Menezes AH, Iowa Midwest Neurosurgical Society Semi-Annual Meeting, Des Moines, IA
• Intrathecal baclofen for intractable spasticity.
  Ryken TC, Hitchon PW, Iowa Midwest Neurosurgical Society Semi-Annual Meeting, Iowa City, IA
• Growth factor interaction in cultured glia.
  Ryken TC, Traynelis VC, University of Iowa, Iowa City, IA
• Cervicomedullary compression in achondroplasia.
  Ryken TC, Menezes AH, Iowa Midwest Neurosurgical Society Semi-Annual Meeting, Omaha, NE
• Cytotoxicity of polyunsaturated fatty acids in malignant glioma.
  Ryken TC, Traynelis VC, Surgery Residents and Fellows Research Day, University of Iowa, Iowa City, IA
• Biomechanical testing of anterior cervical plating systems.
  Ryken TC, Traynelis VC, Iowa-Minnesota Resident Research Day, Iowa City, IA
• Lipid metabolism in cultured malignant glioma.
  Ryken TC, Sandra A, Traynelis VC, University of Iowa Neuroscience Symposium, Iowa City, IA
• Biomechanical characteristics of Caspar and Synthes plates used to stabilize cervical spines before and after cyclic loading.
  Goel V, Clausen J, Ryken TC, Traynelis VC, 17th Annual Meeting of the American Society of Biomechanics, Iowa City, IA
• Fluorescent ceramide labeling of normal and transformed glia.
  Ryken TC, Sandra A, Traynelis VC, Iowa Midwest Neurosurgical Society Semi-Annual Meeting, Iowa City, IA
• Use of fluorescent ceramide probes in cultured glia.
  Ryken TC, Sandra A, Traynelis VC, University of Iowa College of Medicine Research Day, Iowa City, IA
• Biomechanical analysis of anterior cervical plates and screws.
  Ryken TC, Traynelis VC, University of Iowa Department of Surgery Residents and Fellows Research Day, Iowa City, IA
• Cytotoxic potential of cis-parinaric acid in glioma: potential for chemotherapeutic use.
  Ryken TC, Traynelis VC, Iowa-Minnesota Resident Research Day, Minneapolis, MN
• Breakfast Seminar: Frameless Radiosurgery.
  Meeks S and Ryken TC, LINVAC Radiosurgery Scientific Program, Lake Buena Vista, Florida
• High intensity focused ultrasound for cooking tumor non-invasively.
  Long T, Amin V, Roberts R, Thompson RB, McClure S, Ryken T, Iowa Academy of Science Conference
• Assessment of primary and salvage lateral mass screw insertion torque in a cadaveric model.
  Lovick DS, Ryken TC, Traynelis VC, Dexter F, Journal of Spinal Disorders 10(5):431-435
• Treatment of Down's syndrome-associated craniovertebral junction abnormalities.
  Taggard DA, Menezes AH, Ryken TC, Journal of Neurosurgery 93 (2 Suppl): 205-213
• Electron microscopic examination of C6 glioma stimulated with glia maturation factor.
  Ryken TC, Turner JW, Theriac M, Lim R, Proceedings of the 23rd Annual Iowa Electron Microscopy Colloquium, Ames, IA
• Morphology of C6 glioma stimulated with glia maturation factor.
  Ryken TC, Turner JW, Lim R, Abstracts of Medical Student Research Day, University of Iowa, Iowa City, IA
• Induction of cytoskeletal alterations in C6 glioma by glia maturation factor.
  Ryken TC, Lim R, Abstracts of the 28th Annual National Student Research Forum, Galveston, TX
• Coculture of normal rat astrocytes and C6 rat glioma in vitro.
  Ryken TC, Turner JW, Proceedings of the 25th Annual Iowa Electron Microscopy Colloquium, Ames, IA
• Scanning electron microscopy and filtration of bile in a liver transplant patient with biliary sepsis.
  Turner JW, Sargent ER, Sandra A, Ryken TC, Proceedings of the 26th Annual Iowa Electron Microscopy Colloquium, Ames, IA
• Effects of acidic fibroblast growth factor and transforming growth factor-beta on normal rat astrocytes in vitro.
  Ryken TC, Turner JW, Sandra A, Lim R, Proceedings of the 27th Annual Iowa Electron Microscopy Colloquium, Ames, IA
• Ultrastructure of endothelium in vitro: analysis of difference in vascular bed, species and culture conditions.
  Turner JW, Sandra A, Ryken TC, Barr R, Journal of Electron Microscopy Techniques 7(2):146
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Lectures

• Somatosensory systems. 
  Neurosurgical Grand Rounds, University of Iowa, Iowa City, IA
• Neurosurgical considerations in pediatric trauma. 
  Pediatric Neurosurgery Conference, Neuroscience Nursing, University of Iowa, Iowa City, IA
• Biomechanics of anterior cervical plates. 
  Iowa-Midwest Neurosurgical Society Semiannual Meeting, Omaha, NE
• Subarachnoid hemorrhage: clinical considerations. 
  Current Concepts in Critical Care Medicine, Syracuse, NY
• Update on malignant brain tumor management. 
  Multiple Locations, 2007, 2010
• Novel concepts in the care of brain tumor patients. 
  Oncology Nursing Seminar-Regional Meeting, Iowa City, IA
• Development of guidelines for spinal fusion. 
  Iowa Midwest Neurosurgical Society Meeting
• Advances in glioma management. 
  Oncology Grand Rounds, Mercy Medical Center, Des Moines, IA
• Advances in neurosurgical glioma management. 
  Cancer Center Forum, University of Iowa, Iowa City, IA
• Image guided neurosurgery. 
  Department of Anesthesia, Grand Rounds, University of Iowa, Iowa City, IA
• Update on implantable chemotherapy for glioma. 
  Clinical Cancer Center Conference, University of Iowa, Iowa City, IA
• Management of malignant brain tumors. 
  Multiple Locations, 2001, 2007, 2009
• Multimodality imaging of brain tumors. 
  Iowa Society of Radiologic Technicians, Cedar Rapids, Iowa
• Ultrasound assisted image guided neurosurgery. 
  Midwest Neurosurgical Society Annual Meeting, Omaha, NE
• Cervical spine trauma assessment and management. 
  34th Annual Iowa Head and Neck Cancer and Reconstructive Surgery Course, Course, Iowa City, IA
• Malignant Gliomas: A Surgeon’s Perspective. 
  LINVAC Radiosurgery Scientific Program, Lake Buena Vista, Florida
• Head and Neck Trauma Course: C-Spine and Neurosurgical Clearance. 
  Multiple Locations, 2003
• Detection of Changes in Gene Expression During Astrocytic Differentiation and Potential Implications for Gliomas. 
  Iowa-Minnesota Resident Research Day, Iowa City, Iowa
• Transsphenoidal Surgery. 
  Iowa Basic Science Course in Otolaryngology, 2003: Iowa City, Iowa
• Brain Tumors. 
  CNRN Review Course, Iowa City, Iowa
• Malignant Brain Tumors: Overview of Management. 
  Oncology Nursing Update 2006, Sioux City, Iowa
• Update on Newly Diagnosed Glioblastoma Multiforme and Recurrent Anaplastic Astrocytoma. 
  Tumor Conference at The Finley Hospital in Dubuque, Iowa
• Malignant Brain Tumors. 
  7th Annual Oncology Fall Nursing Conference, Des Moines, Iowa
• Management of Malignant Glioma. 
  Multiple Locations, 2004, 2005, 2006
• Update on Evidence Based Management of Primary Brain Tumors. 
  University of Iowa Department of Neurosurgery Resident Conference
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