ThomasDuen-ShyrWangMDPhD

Esophagus Disease, Gastrointestinal Cancer, Hepatology & Liver Transplantation

Professor of Medicine, Biomedical Engineering, Mechanical Engineering; H. Marvin Pollard Collegiate Professor of Endoscopy Research

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Office
1500 E Medical Center Dr
Ann Arbor, MI 48109
Phone+1 734-936-4000

Education & Training

Stanford Health Care2000 - 2003
Boston Medical Center1998 - 2000
Boston University Medical CenterResidency, Internal Medicine, 2000
Harvard Medical SchoolClass of 1998

Certifications & Licensure

MI State Medical License 2007 - 2026
CA State Medical License 2000 - 2020
American Board of Internal Medicine Gastroenterology

Awards, Honors, & Recognition

H. Marvin Pollard Collegiate Professor of Endoscopy Research University of Michigan, 2015
Fellow (AGAF) American Gastroenterological Association, 2012
League of Research Excellence University of Michigan, 2011
Jerome W. Conn Award for Excellence in Research University of Michigan, 2011
Elected Member The American Society for Clinical Investigation, 2009
Clinical Scientist Development Award Doris Duke Charitable Foundation, 2006
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Clinical Trials

A In-Vivo Esophageal Protocol for Detection of Neoplasia in the Digestive Tract Start of enrollment: 2012 Jul 01
Completed
Phase 1
A Phase I In-Vivo Peptide Applied in the Right Colon Start of enrollment: 2013 Feb 01
Completed
Phase 1
Study of KCC Peptide Application in the Colon Start of enrollment: 2014 Jun 01
Completed
Phase 1

Publications & Presentations

PubMed

166 citations
Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis
Xiang Xue, Sadeesh K. Ramakrishnan, Kevin Weisz, Daniel Triner, Liwei Xie
Cell Metabolism. 2016-09-13
38 citations
EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging
Juan Zhou, Bishnu P. Joshi, Xiyu Duan, Asha Pant, Zhen Qiu
Clinical and Translational Gastroenterology. 2015-07-16
167 citations
Neonatal acquisition of Clostridia species protects against colonization by bacterial pathogens
Yun Gi Kim, Kei Sakamoto, Sang Uk Seo, Joseph M. Pickard, Merritt Gillilland
Science. 2017-04-21

Journal Articles

Molecular endoscopy for targeted imaging in the digestive tract: Emerging trends in endoscopic imaging
Lee JH, Wang TD, The Lancet Gastroenterology & Hepatology, 10/1/2016
In Vivo Photoacoustic Tomography of EGFR Overexpressed in Hepatocellular Carcinoma Mouse Xenograft
Zhou Q, Li Z, Zhou J, Joshi BP, Li G, Duan X, Kuick R, Owens SR, Wang TD, Photoacoustics, 9/1/2016

Press Mentions

VUMC Researchers Receive Grant from the National Heart, Lung, and Blood Institute to Develop Biomarkers to Improve the Diagnosis of Acute Heart FailureMay 26th, 2021

Grant Support

Early Detection of Colorectal Cancer on Near-Infrared Molecular EndoscopyNIH/NCI2016–2021
Multiplexed Imaging of Biliary Intra-Epithelial NeoplasiaNational Cancer Institute2015–2020
Multiplexed Multi-Modal Endoscopic Imaging of Cancer BiomarkersNational Cancer Institute2015–2020
Multi-Photon Endomicroscope for Real-Time In Vivo Vertical SectioningNIH/NIBIB2015–2019
Targeted Multi-Spectral Dual Axes Confocal Imaging Of In Vivo Molecular ExpressioNational Cancer Institute2010–2012
Multi-Spectral Targeted Imaging For Early Detection Of Cancer In Barrett'S EsophaNational Cancer Institute2011
Proj 1: In Vivo Optical Molecular Imaging With Fluorescence PeptidesNational Cancer Institute2008–2011
Primary Project 1National Cancer Institute2008–2011
In Viro Detection Of Neoplasia In The Digestive TractNational Cancer Institute2008–2011
Administrative CoreNational Cancer Institute2008–2011
Peptide Reagents For Detection Of Colonic DysplasiaNational Institute Of Diabetes And Digestive And Kidney Diseases2007
Novel Confocal Microscope For Molecular/Cellular ImagingNational Institute Of Diabetes And Digestive And Kidney Diseases2007
Miniature Confocal Theta Flourescence MicroscopeNational Cancer Institute2007
Peptide Reagents For Detection Of Colonic DysplasiaNational Institute Of Diabetes And Digestive And Kidney Diseases2006–2007
Novel Confocal Microscope For Molecular/Cellular ImagingNational Institute Of Diabetes And Digestive And Kidney Diseases2006–2007
Miniature Confocal Theta Flourescence MicroscopeNational Cancer Institute2006–2007

Committees

Section Physiology, OESO Permanent Scientific Committee 2014 - Present
Councilor, AGA Institute Council section of Imaging & Advanced Technology 2013 - Present
Reviewer, NIH Study Section ZRG1 SBIB-D 2015 - 2015
Reviewer, NIH Study Section ZRG1 SBIB-J 2013 - 2013
Reviewer, NIH Study Section ZRG1 SBIB-V 2009 - 2010