Thomas E Stinchcombe MD

Clinical Trials

• Combination Chemotherapy, Bev, RT, and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer Start of enrollment: 2006 Jan 01

  Completed

  Phase 1, Phase 2

• Whole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lung Cancer Start of enrollment: 2005 May 01

  Terminated

  Phase 2

• Ph II Gemcitabine, Erlotinib, and Gemcitabine With Erlotinib/Elderly Patients W/ IIIB/IV NSCLC Start of enrollment: 2006 Mar 01

  Completed

  Phase 2

• Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Gemcitabine in Treating Patients With Advanced Metastatic Solid Tumors Start of enrollment: 2006 Aug 01

  Completed

  Phase 1

• Study of Abraxane and Carboplatin to Treat Small Cell Lung Cancer Start of enrollment: 2006 Apr 01

  Terminated

  Phase 2

• Ph II of Vinflunine and Cetuximab in Second Line Treatment of NSCLC Start of enrollment: 2007 Aug 01

  Terminated

  Phase 2

• Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Metastatic Solid Tumors Start of enrollment: 2004 Dec 01

  Completed

  Phase 1

• Sorafenib Combined With Cisplatin and Etoposide or Carboplatin and Pemetrexed in Treating Patients With Metastatic Solid Tumors Start of enrollment: 2007 Sep 01

  Completed

  Phase 1

• Pazopanib In Stage IIIB/IV NSCLC Lung Cancer After Progression on First Line Therapy Containing Bevacizumab Start of enrollment: 2010 Dec 01

  Completed

  Phase 2

• Carboplatin, Pemetrexed Disodium, and Bevacizumab for Patients With Stage III or IV Non-Small Cell Lung Cancer Who Are Light/Never Smokers Start of enrollment: 2010 Mar 01

  Completed

  Phase 2

• NCI 8873: Randomized Phase II Study of Single Agent OSI-906, an Oral, Small Molecule, Tyrosine Kinase Inhibitor (TKI) of the Insulin Growth Factor-1 Receptor (IGF-1R) Versus Topotecan for the Treatment of Patients With Relapsed Small Cell Lung Cancer (SCL Start of enrollment: 2011 Jun 01
• Erlotinib Hydrochloride With or Without Bevacizumab in Treating Patients With Stage IV Non-small Cell Lung Cancer With Epidermal Growth Factor Receptor Mutations Start of enrollment: 2012 Mar 16

  Completed

  Phase 2

• Temozolomide With or Without Veliparib in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer Start of enrollment: 2012 Jun 01

  Completed

  Phase 2

• An Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026) Start of enrollment: 2014 Mar 27

  Completed

  Phase 3

• Trial of Brigatinib After Treatment With Next-Generation ALK Inhibitors Start of enrollment: 2017 Mar 09

  Terminated

  Phase 2

• Pembrolizumab vs Topotecan in Patients With Small Cell Lung Cancer Start of enrollment: 2017 May 20

  Terminated

  Phase 2

• A Study Osimertinib in Patients With Stage 4 Non-small Cell Lung Cancer With Uncommon EGFR Mutations Start of enrollment: 2018 Jun 30

  Completed

  Phase 2

• Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease Start of enrollment: 2019 Jun 27

  Terminated

  Phase 1

• Study of ADXS-503 With or Without Pembro in Subjects With Metastatic Non-Small Cell Lung Cancer Start of enrollment: 2019 Feb 12

  Completed

  Phase 1, Phase 2

• Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving Osimertinib Start of enrollment: 2020 Jul 09

  Terminated

  Phase 2

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