ThomasOrtelMD

Hematology • Durham, NC

Professor of Medicine, Duke University

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Office
Duke Medical Ctr
Durham, NC 27710
Phone+1 919-620-4467

Education & Training

Duke University HospitalFellowship, Hematology and Medical Oncology, 1988 - 1991
Duke University HospitalResidency, Internal Medicine, 1985 - 1988
Indiana University School of MedicineClass of 1985

Certifications & Licensure

NC State Medical License 1989 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2008-2014
Top MD Consumers Checkbook
Whos Who in Medicine and Healthcare Marquis Whos Who

Clinical Trials

Optimal Platelet Dose Strategy for Management of Thrombocytopenia Start of enrollment: 2004 Jul 01
Completed
Phase 3
Fresh-Frozen Plasma Infusions to Reduce Risk of Bleeding Related to Invasive Procedures Start of enrollment: 2006 Mar 01
Withdrawn
Phase 3
Risk of Developing Antibodies to Heparin-PF4 After Heart Surgery Start of enrollment: 2006 Jun 01
Completed
Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome Start of enrollment: 2006 Jun 01
Recruiting
Pharmacokinetic Study of Fondaparinux in Outpatients With Renal Dysfunction Start of enrollment: 2007 Aug 01
Withdrawn
Not Applicable
Evaluating the Presence of Blood Clots in People With Heparin-Induced Thrombocytopenia (HIT) (The HOT Study) Start of enrollment: 2008 Jan 01
Terminated
Effectiveness of Bridging Anticoagulation for Surgery (The BRIDGE Study) Start of enrollment: 2009 Jul 01
Completed
Phase 3
Evaluating the Effectiveness of Adding Rituximab to Standard Treatment for Thrombotic Thrombocytopenic Purpura (TTP) Start of enrollment: 2009 Apr 01
Terminated
Phase 3
Clinical Decision Rule Validation Study to Predict Low Recurrent Risk in Patients With Unprovoked Venous Thromboembolism Start of enrollment: 2008 Nov 01
Completed
Phase 4
Red Cell Storage Duration Study Start of enrollment: 2010 Jan 01
Completed
Phase 3
Initial Treatment of Patients With Immune Thrombocytopenic Purpura Start of enrollment: 2010 Jan 01
Terminated
Phase 3
"Pharmacokinetic Study of Fondaparinux in Inpatients With Renal Dysfunction" Start of enrollment: 2010 May 01
Completed
Phase 1
Heparin-Induced Thrombocytopenia - Retrospective Analysis of Data on Incidence and Outcomes Study Start of enrollment: 2010 Jun 01
Completed
A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP) Start of enrollment: 2017 Oct 13
Completed
Phase 3
Roles: Principal Investigator
A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura Start of enrollment: 2021 Apr 14
Recruiting
Phase 3
Roles: Principal Investigator
A Study of TAK-755 (rADAMTS13) With Little to No Plasma Exchange (PEX) Treatment in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP) Start of enrollment: 2023 Mar 21
Recruiting
Phase 2
Roles: Principal Investigator
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Publications & Presentations

PubMed

On-Treatment Change in d-Dimer Is Associated With Differential Outcomes Among Therapeutic Dose Heparin-Treated Noncritically Ill Patients Hospitalized for COVID-19.
Lana Wahid, Joshua Froess, Thomas L Ortel, Ryan Zarychanski, Jeffrey S Berger
Arteriosclerosis, Thrombosis, and Vascular Biology. 2024-12-05
Genetic and genomic associations in antiphospholipid syndrome: A systematic review.
Joseph Zouein, Nabih Naim, Diane M Spencer, Thomas L Ortel
Autoimmunity Reviews. 2024-11-30
An update on laboratory detection and interpretation of antiphospholipid antibodies for diagnosis of antiphospholipid syndrome: guidance from the ISTH-SSC Subcommittee...
Katrien M J Devreese, Maria Laura Bertolaccini, D Ware Branch, Bas de Laat, Doruk Erkan
Journal of Thrombosis and Haemostasis. 2024-11-05

Journal Articles

Automated Versus Manual Data Extraction of the Padua Prediction Score for Venous Thromboembolism Risk in Hospitalized Older Adults
David Gallagher, Juliessa M Pavon, Harvey J Cohen, Thomas L Ortel, Applied Clinical Informatics

Abstracts/Posters

Risk Factors Associated with 6-Month Recurrent VTE Among Patients in Two Large Population-Based Surveillance Systems
Thomas L. Ortel, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
Cancer- Associated Venous Thromboembolism (VTE) Characteristics in Blacks Compared to Whites in Durham County, North Carolina
Thomas L. Ortel, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

Hemostasis and Thrombosis
61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
Laboratory Criteria for Antiphospholipid Syndrome: Reply
American Society of Hematology (ASH), Hollywood, California - 10/12/2012

Other

Laboratory Criteria for Antiphospholipid Syndrome: Reply
Thomas Ortel, MD, Journal of Thrombosis and Haemostasis
https://www.doximity.com/articles/9d2ed495-af3c-4907-8efa-27b82eedb4cc
UpToDate, Wolters Kluwer Health - 2012-03-19

Press Mentions

HEP-COVID: Therapeutic-Dose Heparin Effective in Non-ICU PatientsOctober 12th, 2021
Tackle the Triglycerides to Reduce ASCVD Risk, ACC SaysJuly 28th, 2021
Drug Problems: Hematologic Complications of Illicit Drug UseNovember 15th, 2019
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