ThomasMichelMD

PubMed

• 8 citations
  Anti-breast cancer potential of Anonidium mannii (Oliv.) Engl. & Diels barks ethanolic extract: UPLC-ESI-QTOF-MS detection of anticancer alkaloids.
  Francine Azegha Mefegue, Thomas Michel, Eutrophe Le Doux Kamto, Larissa Vanelle Kenmogne, Charline Florence Awounfack
  Journal of Ethnopharmacology. 2021-04-21
• 73 citations
  Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis.
  Rui Miao, Cong Jiang, Winston Y Chang, Haiwei Zhang, Jinsu An
  Immunity. 2023-11-14
• 1391 citations
  Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19.
  Muthiah Vaduganathan, Orly Vardeny, Thomas Michel, John J.V. McMurray, Marc A. Pfeffer
  The New England Journal of Medicine. 2020-03-30

Journal Articles

• Chemogenetic generation of hydrogen peroxide (H2O2) in the heart induces severe cardiac dysfunction  
  Steinhorn B, Sorrentino A, Badole S, Belousov V, Michel T, Nature Comm, 1/1/2018
• Insulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH oxidase isoforms NOX2 and NOX4  
  Steinhorn B, Sartoretto J, Sorrentino A, Romero N, Kalwa H, Abel ED, Michel T, Free Radic Biol Med, 1/1/2017
• The future of vascular medicine  
  Kinlay S, Michel T, Leopold J, Circulation, 1/1/2016
• Nitric oxide mediates glial-induced neurodegeneration in Alexander disease  
  Wang L, Hageman TL, Kalwa H, Michel T, Messing A, and Feany MB, Nature Communications, 1/1/2015
• Rondo in E: Nitroglycerin, nitric oxide, and endothelial therapeutics  
  Steinhorn B, Loscalzo J and Michel T, New England Journal of Medicine, 1/1/2015
• Phosphatidylcholine Transfer Protein interacts with Thioesterase Superfamily Member 2 to attenuate insulin signaling  
  Ersoy B, Tarun A, D'Aquino K, Hancer NJ, Ukomadu C, White MF, Michel T, Manning BD and Cohen DE, Science Signaling, 1/30/2013
• R is for Arginine  
  Michel T, Circulation, 1/1/2013
• Thiol-metabolizing proteins and endothelial redox state: Differential modulation of eNOS and biopterin pathways  
  Sugiyama T and Michel T, Am J Physiol Heart Circ Phys, 1/1/2010
• Cellular signaling and NO production  
  Michel T and Vanhoutte PM, Pflugers Archiv Pharm, 1/1/2010
• NO way to relax: the complexities of coupling nitric oxide synthase pathways in the heart  
  Michel T, Circulation, 1/1/2010
• PPAR-gamma in the endothelium regulates metabolic responses to high-fat diet in mice  
  Kanda T, Brown JD, Orasanu G, Vogel S, Gonzalez FJ, Sartoretto J, Michel T, Plutzky J, J Clin Invest, 1/1/2009
• Regulation of Rac1 by simvistatin in endothelial cells: differential roles of AMP-activated protein kinase and calmodulin-dependent kinase kinase-Beta  
  Kou R, Sartoretto J and Michel T, J Biol Chem, 1/1/2009
• Tetrahydrobiopterin recycling: a key determinant of eNOS-dependent signaling pathways in vascular endothelium  
  Sugiyama T, Levy B and Michel T, J Biol Chem, 1/1/2009
• Endothelial nitric oxide synthase negatively regulates hydrogen peroxide-induced AMP-activated protein kinase activation in endothelial cells  
  Jin B, Sartoretto J, Gladyshev V, and Michel T, Proc Natl Acad Sci USA, 1/1/2009
• Regulation of VASP phosphorylation in cardiac myocytes: Differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic...  
  Sartoretto J, Jin B, Bauer M, Gertler F, Liao R and Michel T, Am J Physiol Heart Circ Phys, 1/1/2009
• Sphingosine 1-phosphate and control of vascular tone  
  Igarashi J and Michel T, Cardiovascular Research, 1/1/2009
• ANP-initiated cGMP pathways regulate VASP phosphorylation and angiogenesis in vascular endothelium  
  Chen H, Levine Y, Golan DE, Michel T, and Lin AJ, J Biol Chem, 1/1/2008
• The enigma of sphingosine 1-phosphate synthesis: A novel role for endothelial sphingosine kinases  
  Igarashi J and Michel T, Circulation Research, 1/1/2008
• S1P and eNOS regulation  
  Igarashi J, Michel T, Biochim Biophys Acta, 1/1/2008
• Agonist-modulated regulation of AMPK-activated protein kinase in endothelial cells: Evidence for an AMPK-Rac1-Akt-eNOS pathway  
  Levine Y, Li GK and Michel T, J Biol Chem, 1/1/2007
• Epinephrine regulation of eNOS: roles of Rac1 and Beta3-adrenergic receptors in endothelial NO signaling  
  Kou R and Michel T, J Biol Chem, 1/1/2007
• The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo  
  Atochin D et al, J Clin Invest, 1/1/2007
• Effects of S-nitrosation of nitric oxide synthase  
  Mitchell, DA, Michel T and Marletta M, Adv Exp Biol, 1/1/2007
• Life history of eNOS: Partners and pathways  
  Dudzinski D and Michel T, Cardiovascular Research, 1/1/2007
• Nitric oxide signaling comes of age: 20 years and thriving  
  Lamas, S, Lowenstein CJ and Michel T, Cardiovascular Research, 1/1/2007
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Books/Book Chapters

• Hemostasis and Thrombosis 
  Chapter: The vascular biology of nitric oxide and NO synthases. 
  Page 536 - 548Maron BA and Michel TEditors: W. Baird.Lippincott Williams and Wilkins, PhiladelphiaEdition 5th,2012
• Goodman and Gilman's Pharmacological Basis of Therapeutics 
  Chapter: Treatment of myocardial ischemia and hypertension. 
  Page 745 - 788Michel T and Hoffman BBEditors: L. Brunton.McGraw Hill, NYEdition 12th,2010
• Hemostasis and Thrombosis 
  Chapter: Vascular biology of nitric oxide and NO synthases. 
  Page 653 - 657Dudzinski D and Michel TEditors: L. Clowes.Lippincott Williams and Wilkins, PhiladelphiaEdition 4th,2006
• Goodman and Gilman's Pharmacological Basis of Therapeutics 
  Chapter: Treatment of myocardial ischemia. 
  Page 823 - 844Michel TEditors: L Brunton.McGraw Hill, New YorkEdition 11th,2005
• Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy 
  Chapter: Pharmacology of Vascular Tone 
  Page 317 - 334Yeh DC and Michel TEditors: DE Golan, et al.Lippincott Williams and Wilkins, Baltimore, MD2004
• Bioluminescence & Chemiluminescence: Progress & Current Applications 
  Chapter: Mechanism of firefly flash control: NO inhibition of oxygen consumption in lantern mitochondria is reversed by light. 
  Page 25 - 28Aprille JR, Lagace CJ, Lewis SM, Michel T, Modica-Napolitano JS, Trimmer BA and Zayas RMEditors: Stanley PE & Kricka LJ.World Scientific Publishing, Singapore2002
• Melmon and Morelli's Clinical Pharmacology: Basic Principles in Therapeutics 
  Chapter: Stable coronary artery disease: angina and atherosclerosis. 
  Page 114 - 131Michel T and Weinfeld MSEditors: Melmon KL, et al.McGraw Hill, New YorkEdition 4th,2000
• Nitric Oxide and the Cardiovascular System 
  Chapter: Cell and molecular biology of nitric oxide synthases. 
  Page 11 - 32Feron O and Michel TEditors: J. Loscalzo and J. A. Vita.Humana Press, Totowa, NJ2000
• Coronary Artery Spasm 
  Chapter: Regulatory mechanisms of endothelial nitric oxide synthase. 
  Page 19 - 25Sase K and Michel TEditors: Yasue H.Axel Springer, Tokyo, Japan2000
• Endothelium, Nitric Oxide and Atherosclerosis 
  Chapter: Molecular and cellular regulation of endothelial nitric oxide synthase. 
  Page 29 - 37Downey W and Michel TEditors: Goodman R and Panda J.Futura, NY1999
• Textbook of Molecular Medicine 
  Chapter: Endothelium-derived nitric oxide and the control of vascular tone. 
  Michel T and Lamas SEditors: Jameson L.Blackwell, Cambridge, MA1999
• Molecular Biology of Cardiovascular Disease 
  Chapter: Molecular regulation of nitric oxide synthases. 
  Page 141 - 160Michel T, Sase K and Lamas SEditors: Marks A and Taubman M.Marcel Dekker, NY1997
• Nitric Oxide and the Lung 
  Chapter: Molecular biological features of the nitric oxide synthases. 
  Page 59 - 68Lamas S and Michel TEditors: Zapol W.Marcel Dekker, NY1996
• Methods in Nitric Oxide Research 
  Chapter: Molecular biological analysis of nitric oxide synthases. 
  Page 161 - 176Michel T, Xie QW, Nathan CEditors: Feelisch M and Stamler J.Wiley1996
• Therapy of Heart Failure: Basic Science and Clinical Aspects 
  Chapter: Endothelial cell-derived vasoactive and inotropic paracrine factors. 
  Page 515 - 536Michel T, Kramer BK, Kelly RAEditors: Gwathmey J.Marcel Dekker1992
• Biochemical Actions of Hormones 
  Chapter: Regulation of adenylate cyclase by adrenergic receptors. 
  Page 43 - 68Michel T, Hoffman BB, Lefkowitz RJEditors: Litwack G.1982
• The Biology of Nitric Oxide 
  Chapter: The constitutive endothelial NO synthase gene: implications for its evolution and cellular regulation. 
  Page 1 - 4Robinson LJ, Morton CC and Michel TEditors: S. Moncada.Portland Press, London
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Other

• Nitric oxide synthase 3. 
  Michel, T., UCSD-Nature Molecule Pages
  1/1/2009
• Strategic Advisory Group on Education White Paper. 
  Michel T, Platt O, et al, Harvard Medical School (pp. 1-29)
  hms.harvard.edu/public/strategy/sage.pdf
  Boston MA - 1/1/2008
• Identification and mathematical modeling of basic transport processes in eutrophic lake systems. 
  Michel J, Michel T, Bossert WH, Harvard Lake Study, Division of Engineering and Applied Physics (pp. 1-135)
  Harvard University, Cambridge, MA - 1/1/1976
• Squam Lakes Study Report. 
  Lewis SM, D'Asaro EA and Michel T, Harvard Lake Study, Division of Engineering and Applied Physics (pp. 1-102)
  Harvard University, Cambridge, MA - 1/1/1976
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