ThomasVincentMcDonaldMDFAHA

PubMed

• Employing effective recruitment and retention strategies to engage a diverse pediatric population in genomics research.
  Michelle A Ramos, Katherine E Bonini, Laura Scarimbolo, Nicole R Kelly, Beverly Insel
  American Journal of Human Genetics. 2024-12-05
• Hypertrophic cardiomyopathy and long QT syndrome in cardiac-only Timothy syndrome.
  Nathan R Einhorn, Ritesh S Patel, Jennifer L Bennett, Thomas V McDonald
  Heartrhythm Case Reports. 2023-08-01
• 7 citations
  The TeleKidSeq pilot study: incorporating telehealth into clinical care of children from diverse backgrounds undergoing whole genome sequencing.
  Monisha Sebastin, Jacqueline A Odgis, Sabrina A Suckiel, Katherine E Bonini, Miranda Di Biase
  Pilot and Feasibility Studies. 2023-03-22

Journal Articles

• Regulation of HERG by PIP2.  
  Bian JS, McDonald TV, Pflügers Archiv
• Abnormal Chloride Conductance in Multidrug Resistant HL60/AR Cells.  
  Gollapudi S, McDonald T, Gardner P, Kang N, Gupta S, Cancer Letters
• Regulation of lymphocyte chloride channels.  
  Gardner P, McDonald TV, Nishimoto I, Wagner J, Shumann M, Chen J, Schulman H, Advances in Experimental Medicine and Biology

Books/Book Chapters

• Cardiac Electrophysiology From cell to bedside. 
  Chapter: Gene transfer of membrane channel proteins 
  Fishman GI, McDonald TVEditors: Zipes, DP, Jalife J.W.B. Saunders CompanyEdition 3rd,
• Cardiac Arrhythmias - New Considerations. 
  Chapter: Phenotypic Correlation of Genetic Mutations with Ventricular Arrhythmias 
  Krishnan Y, Chen J, McDonald TVEditors: Francisco R. Breijo-Marquez.

Abstracts/Posters

• Mutant minK alters KvLQT1 trafficking.
  Krumerman A, Melman YF, McDonald TV, Circulation, American Heart Association, 2002 Scientific Sessions
• Physical and Functional Interaction Sites in Cytoplasmic Domains of KCNQ1 and KCNE1 Channel Subunits.
  Chen J, Zheng R, Kanda V, Rojas R, Negro BWA, Antonelli R, Xiao H, McDonald TV, Manuscript In Revision
• Ligand-binding characteristics of the cyclic nucleotide binding domain (CNBD) of the ERG potassium channel and long QT syndrome.
  Zheng R, Negro BWA, Rojas RA, Laska A, Cho S-I, Cheng H, Obeng-Gyimah E, McDonald TV, Biophysical Society Scientific Meeting
• Adrenergic regulation of the HERG potassium channel biosynthesis and function.
  Krishnan Y, Chen J, McDonald TV, Biophysical Society Scientific Meeting
• Physical and functional interactions between the KCNQ1 and KCNE1 C-terminal Domains.
  Chen J, Zheng R, Negro BWA, McDonald TV, Biophysical Society Scientific Meeting
• Physical Interactions Between The Cytoplasmic Domains Of KCNQ1 And KCNE1 Channel Subunits.
  Zheng R, Thompson K, Obeng-Gyimah O, Alessi D, Chen J, McDonald TV, Biophysical Society Scientific Meeting
• Caring for families at risk for sudden death (SD): The inception, organization, and early outcomes of a multidisciplinary (M/D) cardiogenetics clinic.
  Pope KO, Paljevic ED, Walsh CA, McDonald T, and Marion RW, American Society of Human Genetics
• C-terminal interactions between KCNE1 and KCNQ1.
  Chen J, Zheng R, Melman YF, Thomas V. McDonald TV, Biophysical Society Scientific Meeting
• PKC and alpha-adrenergic regulation of HERG channel processing.
  Chen J, Thomas D, McDonald TV, Bian J-S, Biophysical Society Scientific Meeting
• Association of MiRP1 and minK with HERG channels is determined by differential trafficking patterns.
  Um SY, McDonald TV, Circulation, American Heart Association, 2007 Scientific Sessions
• Differential interactions between HERG and KCNE1 or KCNE2.
  Um SY, McDonald TV, Biophysical Society Scientific Meeting
• 14-3-3 and chronic cAMP modulation of HERG channel.
  Li Y, McDonald TV, Biophysical Society Scientific Meeting
• PKA regulates HERG synthesis and interaction with HSP70.
  Chen J, Li Y, Bian JS, McDonald TV, Circulation, American Heart Association, 2006 Scientific Sessions
• 14-3-3 impact on HERG channel: trafficking and kinetics.
  Li Y, McDonald TV, Biophysical Society Scientific Meeting
• AKAP involvement in HERG regulation.
  Li Y, McDonald TV, Biophysical Society Scientific Meeting
• Molecular mechanism of minK-HERG interaction.
  Um SY, McDonald TV, Biophysical Society Scientific Meeting
• Partial purification of a hemolytic protein produced by H pleuropneumoniae and characterization of its mode of action.
  Lalonde G, McDonald T, Meitzner T, Gardner P, OHanley P, Clin Res
• Parallel trafficking and assembly of KvLQT1 and minK.
  Krumerman A, Kagan A, Melman YF, McDonald TV, Biophysical J, Biophysical Society Scientific Meeting
• The K+ channel-binding site for KCNE proteins.
  Melman YF, Krumerman, McDonald, Biophysical J, Biophysical Society Scientific Meeting
• Pip2 Regulation Of Herg K+ Channel.
  Bian J, Cui J, McDonald TV, Biophysical J, Biophysical Society Scientific Meeting
• 14-3-3 mediates PKA regulation of the HERG K+ channel.
  Kagan A, McDonald TV, Biophysical J, Biophysical Society Scientific Meeting
• Loss of function of HERG K+ channel by mutations in the cyclic nucleotide-binding domain.
  Cui J, Qin D, Kagan A, Mathew J, McDonald TV, Biophysical Journal
• Alterations in myocardial potassium currents in a mouse model of cardiac troponin T-related familial hypertrophic cardiomyopathy.
  Doan TM, McDonald TV, Tardiff JC, Biophysical Journal
• The transmembrane domain confers functional specificity of the KCNE gene family.
  Melman YF, de la Luna S, McDonald TV, Biophysical Journal
• Dominant Mechanisms in LQT Mutations of HERG.
  Kagan A, Qin D, Zhen M, Fishman, GI, McDonald, TV, Biophysical Journal
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Lectures

• Adrenergic regulation of the HERG potassium channel. 
  Cardiology Grand Rounds, NYU School of Medicine
• Voltage-Gated K+ Channels: Regulations & Modulation. 
  The 2007 Annual Meeting of the Biophysical Society
• Signaling and Regulation of Cellular Electrophysiology. 
  American Heart Association Scientific Sessions
• Hereditary Arrhythmias: Einstein-Montefiore Cardiogenetics Program. 
  Jacobi Medical Center, Medical Grand Rounds
• IKs: Probing the interaction of KCNQ1 and KCNE1. 
  Cardiovascular Research Center, Rhode Island Hospital/Brown University School of Medicine
• Hereditary Arrhythmias: An Update on the Einstein-Montefiore CardioGenetics Program. 
  Montefiore-Einstein, Cardiology Grand Rounds
• Regulation of HERG channel bio-processing. 
  Hengstberger Symposium: The Long QT Syndrome – From Molecular Mechanisms to Arrhythmias, Heidelberg
• Cardiac K+ channel regulation: Long QT and beyond. 
  Internal Faculty Seminar, AECOM
• HERG channel regulation, Long QT and beyond. 
  Cardiovascular Research Seminar, Beth Israel Deaconess Medical Center, Harvard Medical School
• Ion Channel Defects in SIDS/SUDS. 
  CHaM Pediatric Heart Center Grand Rounds
• Protein-Protein Interactions and Modulation of Repolarizing Currents. 
• CardioGenetics Clinic for Workup, Counseling and Treatment of SIDS/SUDS. 
  Montefiore/Einstein Pediatrics Alumni Day Seminar
• Ion Channel Defects in SIDS/SUDS. 
  Grand Rounds, the Office of Chief Medical Examiner, New York City
• Sudden Death in the Young with a ‘Normal’ Heart. 
  Cardiovascular Science at the Heart of Medicine, Einstein Alumni Association Seminar
• The Einstein-Montefiore CardioGenetics Clinic: A Multidisciplinary Approach to Sudden Cardiac Death. 
  Kennedy Center Seminars in Translational Neurogenetics, AECOM
• Adrenergic regulation of HERG/IKr. 
  Department of Pharmacology, Columbia University, New York, NY
• Molecular mechanisms of Long QT Syndrome. 
  Division of Cardiovascular Medicine, Stanford University, Stanford, CA
• Regulation of HERG channels by cAMP/PKA. 
  Department of Physiology, University of Medicine and Dentistry of New Jersey, Newark
• The Long QT Syndrome: Clinical Correlates of Basic Research. 
  Albert Einstein College of Medicine, Medical Resident’s Noontime Seminar
• What Practicing Cardiologists Should Know About Basic Cardiac Electrophysiology: Bench-to-Bedside. 
  Albert Einstein College of Medicine-Weiler/Montefiore Hospital/Cardiology Fellows Lecture
• The Long QT Syndrome: Genes & Drugs. 
  Albert Einstein College of Medicine/Montefiore Medical Center, Medical Grand Rounds
• Adrenergic Modification of Channels in the Long QT Syndrome. 
  Cornell University School of Medicine, Cardiology Grand Rounds
• Dynamic control of hERG activity by cAMP, PKA and interactions with 14-3-3. 
  Novartis Foundation Symposium, London
• K Channel Subunits and Sudden Death. 
  Department of Biology, Ithaca College
• From sudden death to structure - living and dying with K channel subunits. 
  Internal Faculty Seminar, AECOM
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