ThomasJosephMDPhD

PubMed

• 15 citations
  Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation.
  John T Petroff 2nd, Noah M Dietzen, Ezry Santiago-McRae, Brett Deng, Maya S Washington
  Nature Communications. 2022-11-17
• 14 citations
  Mechanistic insights into volatile anesthetic modulation of K2P channels.
  Aboubacar Wague, Thomas T. Joseph, Kellie A. Woll, Weiming Bu, Kiran A Vaidya
  Elife. 2020-12-21
• 38 citations
  A Streamlined, General Approach for Computing Ligand Binding Free Energies and Its Application to GPCR-Bound Cholesterol.
  Reza Salari, Thomas T. Joseph, Ruchi Lohia, Jérôme Hénin, Grace Brannigan
  Journal of Chemical Theory and Computation. 2018-10-25

Abstracts/Posters

• Real-time perioperative web-based anesthesia information system.
  Joseph, T., Levin, M., and McCormick, P., Anesth and Analg; Society for Technology in Anesthesia annual meeting, Palm Beach, FL, 1/1/2016
• Common internal allosteric network in GLIC.
  Joseph, T., and Mincer, J., MechanismsofAnesthesiaconference, Bonn,Germany, 1/1/2015
• Coarse-grained model of general anesthetic interaction with a pentameric ligand-gated ion channel.
  Joseph, T., and Mincer, J., International Anesthesia Research Society annual meeting, Honolulu, HI, 1/1/2015
• The genomics of real-time drug response during surgery.
  Jeff, J.M., Joseph, T., Owusu-Obeng, A., Ellis, S., Bottinger, E., Gottesman, O., Levin, M., Kenny, E., Biology of Genomes conference, Cold Spring Harbor, NY, 1/1/2014
• Coarse-grained model of general anesthetic interaction with a pentameric ligand-gated ion channel.
  Joseph, T., and Mincer, J., Postgraduate Assembly of the New York State Society of Anesthesiologists, New York, NY, 1/1/2014
• Dynamical effects of RNAi guide-target mismatch in A. aeolicus Argonaute.
  Joseph, T. and Osman, R., International Workshop in Memoriam of Angel Ramirez Ortiz, Madrid, Spain, 1/1/2009
• Rigid body analysis of A. aeolicus Argonaute
  Joseph, T. and Osman, R., Biophysical Society Annual Meeting, Long Beach, CA, 1/1/2008
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Lectures

• Internal allosteric network in GLIC. 
  University of Pennsylvania - 1/1/2015
• Real-time perioperative web-based anesthesia information system. 
  1/1/2015
• A coarse-grained model of general anesthetic interaction with a ligand-gated ion channel. 
  1/1/2014

Other

• Coarse-Grained Simulation Model Reveals Similarities Among General Anesthetics. 
  Joseph, T, Anesthesiology News
  1/1/2015