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Office
101 Nicolls Road
Health Science Center, room 11-021
Stony Brook, NY 11794
Summary
- Thomas Diacovo, MD is the Vice Chair of Research and Chief of Neonatology for the Department of Pediatrics at Stony Brook Children’s Hospital. Dr. Diacovo is a graduate of McGill University, completed residency in pediatrics at Texas Children’s Hospital and neonatology and research fellowship at Boston Children’s Hospital.
Research interests include
(1) elucidating molecular and biophysical mechanisms that regulate hemostasis and thrombosis with emphasis on the development of humanized animal models, new POC technologies, novel pharmacologic agents, and clinical trials focused on critically ill neonates.
(2) Cell signaling with emphasis on the role of class I PI3Ks in regulating adaptive and innate immune responses.
(3) Development and testing of novel blood products for transfusion
PATENTS:
US9686971. Methods for testing anti-thrombotic agents.
US11459306. Compounds, compositions, and methods for treating T-cell acute lymphoblastic leukemia.
US11260071. Method of preventing systemic-to-pulmonary-artery shunt thrombosis.
Education & Training
- Boston Children’s Hospital/Boston Medical CenterFellowship, Neonatal-Perinatal Medicine, 1991 - 1994
- Baylor College of Medicine (Houston)Internship, Pediatrics, 1988 - 1991
- McGill University Faculty of MedicineClass of 1988
Certifications & Licensure
- NY State Medical License 2004 - 2026
- PA State Medical License 2017 - 2024
- MA State Medical License 1991 - 2000
- American Board of Pediatrics Neonatal-Perinatal Medicine
Clinical Trials
- Cangrelor Neonatal PK/PD and Safety Study Start of enrollment: 2017 Jan 03
Publications & Presentations
PubMed
- 199 citationsA novel molecular interaction for the adhesion of follicular CD4 T cells to follicular DC.Kent S. Boles, William Vermi, Fabio Facchetti, Anja Fuchs, Tim Wilson
European Journal of Immunology. 2009-03-01 - 175 citationsHistamine deficiency promotes inflammation-associated carcinogenesis through reduced myeloid maturation and accumulation of CD11b+Ly6G+ immature myeloid cellsXiang Dong Yang, Walden Ai, Samuel Asfaha, Govind Bhagat, Richard A. Friedman
Nature Medicine. 2011-01-01 - 76 citationsThe snake venom protein botrocetin acts as a biological brace to promote dysfunctional platelet aggregationKoichi Fukuda, Teresa A. Doggett, Ian J. Laurenzi, Robert C. Liddington, Thomas G. Diacovo
Nature Structural & Molecular Biology. 2005-01-16
Journal Articles
- Novel Variant Findings and Challenges Associated with the Clinical Integration of Genomic TestingJill L Maron, Kristen Suhrie, Thomas Diacovo, Annemarie Stroustrup, JAMA Pediatrics
Press Mentions
- UPMC Magee-Womens & Children's Hospitals Host NICU Patient, Family ReunionJune 2nd, 2019
- New Wireless Monitors Will Let Parents Cuddle Fragile NewbornsMarch 4th, 2019
Grant Support
- Model Of Platelet Adhesion And Thrombus FormationNational Heart, Lung, And Blood Institute2010–2012
- GPIB Alpha-Vwf-A1 Bond Kinetics In Health And DiseaseNational Heart, Lung, And Blood Institute2010–2011
- P13kdelta Modulation Of Neutrophil TraffickingNational Heart, Lung, And Blood Institute2005–2008
- Structure/Functional Characterization Of Vwf-A1 DomainNational Heart, Lung, And Blood Institute2005–2007
- Structure/Functional Characterization Of Vwf-A1 DomainNational Heart, Lung, And Blood Institute2004
- Structural/Functional Characterization Of Vwf-Al DomainNational Heart, Lung, And Blood Institute2000–2003
- Characterization Of Platelet:Leukocyte InteractionsNational Heart, Lung, And Blood Institute1999–2000
- Platelet/Leukocyte InteractionsNational Heart, Lung, And Blood Institute1998
- Platelet/Leukocyte InteractionsNational Heart, Lung, And Blood Institute1996–1998
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