TerzahM.HortonMDPh.D.

PubMed

• 680 citations
  Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age.
  Marisol Corral-Debrinski, Terzah M. Horton, Marie T. Lott, John M. Shoffner, M F Beal
  Nature Genetics. 1992-12-01
• 52 citations
  Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors.
  Denise Niewerth, Niels E. Franke, Gerrit Jansen, Yehuda G. Assaraf, Johan van Meerloo
  Haematologica. 2013-12-01
• 50 citations
  Children's Oncology Group Trial AALL1231: A Phase III Clinical Trial Testing Bortezomib in Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia and Lymphoma.
  David T Teachey, Meenakshi Devidas, Brent L Wood, Zhiguo Chen, Robert J Hayashi
  Journal of Clinical Oncology. 2022-07-01

Journal Articles

• Transmissible ER Stress Reconfigures the AML Bone Marrow Compartment  
  Saman K Hashmi, Peter Kurre, Terzah M Horton, Nature
• Phase 1/ 2 trial of brentuximab vedotin in combination with gemcitabine for pediatric and young adult patients with relapsed or refractory Hodgkin Lymphoma: A report f...  
  Cole, PD, K McCarten, Q Pei, M Spira, ML Metzger, RA Drachtman, TM Horton, R Bush, SM Blaney, BJ Weidel, KM Kelly, Lancet Oncology, 1/1/2018
• Investigating the biology of relapsed acute leukemia: Proceedings of the therapeutic advances for childhood leukemia and lymphoma (TACL) consortium biology working group  
  Bhojwani, D., MJ Burke, T Horton, DS Ziegler, ML Sulis, KR Schultz, S Izraeli, BH Chang, Pediatric Hematology and Oncology, 1/1/2017
• Analysis of NF- kappaB Pathway Proteins in Pediatric Hodgkin Lymphoma: Correlations with EBV Status and Clinical Outcome�A Children's Oncology Group Study  
  TM Horton,�AM Sheehan,�D Lopez-Terrada,�RE Hutchison,�S Narendra,�M-F Wu,�and H Liu, Lymphoma, 1/1/2012
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Books/Book Chapters

• New Agents for the Treatment of Acute Lymphoblastic Leukaemia 
  Chapter: Trial Designs for the Evaluation of New Agents in Acute Lymphoblastic Leukaemia 
  J. Whitlock and TM HortonEditors: Vaskar Saha and Pamela Kearns.Springer, Manchester, England, United Kingdom
• UpToDate 
  Chapter: Overview of Diagnosis and Presentation of Acute Lymphocytic Leukemia in children I 
  TM Horton and CP SteuberEditors: Rose BD.Wellesley, MA
• UpToDate 
  Chapter: Overview of Diagnosis and Presentation of Acute Lymphocytic Leukemia in children II 
  TM Horton and CP SteuberEditors: Rose BD.Wellesley, MA
• UpToDate 
  Chapter: Overview of the treatment and outcome of acute lymphoblastic leukemia in children-I 
  TM Horton and CP SteuberEditors: Rose BD.Wellesley, MA
• UpToDate 
  Chapter: Overview of the treatment and outcome of acute lymphoblastic leukemia in children-II 
  TM Horton and CP SteuberEditors: Rose BD.Wellesley, MA
• Perspectives on Childhood Cancer 
  Chapter: New drugs in Pediatric Leukemia 
  TM Horton and SL BergEditors: David Poplack.Edition 3rd,
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Abstracts/Posters

• Leukemic Stress Targets the mTOR Pathway to Suppress Residual HSC in the BM Microenvironment
  Terzah M Horton, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Proteomic Landscape of Acute Leukemia: A Comparison between ALL and AML in Adults
  Terzah M Horton, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Complex and Supercomplex Formation and Is Necessary for AML Viability
  Terzah M Horton, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Comprehensive Cell Specific Transcriptome Profiling of a Pediatric Hodgkin Lymphoma Cohort
  Terzah M Horton, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Prognostic Significance of FOXO3 in Pediatric Acute Myeloid Leukemia (AML) Patients Treated with Bortezomib Addition to Standard Therapy: Results from a ChildrenÍs Onc...
  Terzah M Horton, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Proteomic profiling of the unfolded protein response identifies patients benefiting from bortezomib in pediatric acute myeloid leukemia
  Hoff, FW, Y Qiu, W Hu, AA Qutub, AS Gamis, R Aplenc A Kolb, TA Alonzo, ES deBont, SM Kornblau, TM Horton, American Association of Cancer Research, 1/15/2018
• Proteomic landscape of de novo pediatric acute myeloid leukemia
  Hoff, FW, Y Qiu, W Hu,AA Qutub, AS Gamis, R Aplenc, EA Kolb, TA Alonzo, ES deBont, TM Horton, SM Kornblau, American Association of Cancer Research, 1/15/2018
• Pediatric Acute Myeloid leukemia: an evolving proteomic landscape
  Hoff FW, Y Qui, CS Hu, AA Qutub, AS Gamis, R Aplenc EA Kolb TA Alonzo, ESMJK de Bont, SM Kornblau, TM Horton, American Society of Hematology (ASH), 1/4/2018
• AraC-Daunorubicin-Etoposide (ADE) response prediction in pediatric AML patients using a computation biology modeling (CBM) based precision medicine workflow
  NK Singh, M Sauban, RK Raman, R Vidva, A Tyagi, AA Talawdekar, A Kas, S Vali, CR Cogl, SM Kornblau, TM Horton, T Abbasi, American Society of Hematology (ASH), 1/4/2018
• Signatures of Histone modification marks and proteins in pediatric AML: A comparison to adults
  Kijk, AD, FW Hoff, CW Hu, ESJM de Bont, YH Qiu, AA Qutub, TM Horton, SM Kornblau, American Society of Hematology (ASH), 1/3/2018
• RPPA-profiling identified patients with low phosphorylation of HSF1 at serine 326 as potential candidate for bortezomib treatment in addition to standard therapy in pe...
  Hoff FW, SWM Bruggeman, Y Qiu, AS. Gamis, R Aplenc, EA Kolb, TA Alonzo, EJM de Bont, SM Kornblau, TM Horton, American Society of Hematology (ASH), 1/3/2018
• Glucocorticoids Paradoxically Induce Intrinsic Steroid Resistance Through a STAT5-Mediated Survival Mechanism in T-Cell Acute Lymphoblastic Leukemia
  LK Meyer, BJ Huang, R Roy, A Hechmer, AM Wandler, C Delgado-Martin, A Olshen, TM Horton, DT Teachey, KM Shannon, ML Hermiston, American Society of Hematology (ASH), 1/2/2018
• AXL expression in pediatric AML is associated with putative LSC and correlates with a distinct set of proteins including PD-L1
  Ruvolo, PP, FW Hoff, YH Qiu, A Gaiccia, M Andreeff, ESJM deBont, TM Horton, SM Kornblau, American Society of Hematology (ASH), 1/2/2018
• Detection of biomarkers using xMAP technology for high-risk Hodgkin Lymphoma in the setting of a cooperative group Phase III clinical trial
  Dave, H, S VanPelt, G Jenkins, TM Horton, S Alibhani, Q Pei, R Keller, S Castellino, K Kelly, C Bollard, ISCAYAHL meeting, 1/1/2017
• Recognition of Recurrent Protein Expression Patterns in Pediatric Acute Myeloid Leukemia Suggests New Therapeutic Targets
  Fieke W Hoff, Chenyue W Hu, Yihua Qiu, Suk-Young Yoo, Amina Qutub, Eveline S. de Bont, Terzah M. Horton and Steven M. Kornblau, Blood, 1/1/2016
• Recurrent Patterns of Protein Expression Signatures in Pediatric Acute Lymphoblastic Leukemia: Recognition and Therapeutic Guidance
  Fieke W Hoff, Chenyue W Hu, Yihua Qiu, Suk-Young Yoo, Amina Qutub, TM. Horton and Steven M. Kornblau, Blood, 1/1/2016
• Prediction of primary treatment response and outcome in pediatric Hodgkin lymphoma using digital gene expression profiling
  Mottok A. Johnston, RL, FC Chan, DW Scott, DL Friedman, CL Schwartz, KM Kelly, TM Horton, C Steidl, ISHL, 1/1/2016
• Correlating RPPA data with clinical features in pediatric acute Leukemia
  J Sab, SM Kornblau, W Love, TM Horton, Dan L. Duncan Research Symposium, 1/1/2015
• Targeting NEDD8: a novel approach to treating neuroblastoma
  J. Foster, L. Zhang, K. Scorsone, E Barbiere, J. Muscal, G. Jenkins, P. Zage, S. Berg, TM Horton, 1/1/2015
• Identifying proteins for detecting activation of the unfolded protein response
  G. Oyekanmi, Jenkins, G, TM Horton, NCI-Diversity Supplement program, 1/1/2015
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Lectures

• The Mitochondrial Protease, Neurolysin (NLN), Regulates Respiratory Chain Supercomplex Formation and Represents a New Therapeutic Target for AML 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Proteasome Inhibitor therapy for the treatment of hematologic malignancies 
  1/8/2018
• Taking out the Trash: Proteasome inhibitor therapy for hematologic malignancies 
  1/13/2014
• Update on relapsed leukemia and AML COG protocols 
  1/1/2010
• Chemotherapy Combinations for Relapsed/ Refractory HL 
  1/30/2009
• New drugs for the Treatment of Hodgkin Lymphoma 
  1/17/2008
• Toxicity and DLT Attribution in the context of relapsed ALL therapy 
  1/2/2008
• PARP Inhibition and Proteasome Inhibitors: Potential use in Pediatric Hematologic Malignancies 
  1/1/2008
• Temozolomide and PARP inhibition: Bench to Bedside and Back 
  1/1/2008
• Preclinical models of novel drugs in pediatric Hodgkin lymphoma 
  1/27/2007
• New Drug Development for Pediatric Leukemias & Lymphomas 
  1/20/2007
• In vitro Evaluation of the PARP Inhibitor ABT-888 in Combination with Temozolomide for the Treatment of Pediatric Leukemia 
  1/1/2007
• Innovative therapies of childhood malignancies: new pharmacologic agents 
  1/1/2007
• Translation for hematology-oncology patients and their families 
  1/11/2006
• A Phase I study of Bortezomib (PS-341, VELCADE) in Pediatric Patients with Relapsed or Refractory Leukemia 
  1/3/2006
• Childhood Cancer 
  1/1/2006
• Management of Childhood Leukemia 
  1/1/2006
• Anemia of Childhood 
  1/1/2006
• Preclinical applications of basic research 
  1/1/2006
• Ubiquitination and Proteasome Inhibition in Pediatric Hematologic Malignancies 
  1/25/2004
• Metabolism of cyclosporine in patient with histocytic lymphohistiocytosis (HLH) 
  1/21/2004
• Introduction to Cancer Chemotherapy 
  1/10/2004
• Novel Agents for the treatment of pediatric malignancies 
  Houston, TX - 1/1/2004
• Idiopathic thrombotic thrombocytopenia masquerading as hemolytic uremic syndrome 
  1/1/2004
• Sickle Cell Crises 
  1/6/2003
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Other

• Overview of the outcome of acute lymphoblastic leukemia in children 
  Horton TM, Steuber CP
  http://www.uptodate.com/contents/overview-of-the-outcome-of-acute-lymphoblastic-leukemia-in-children
  UpToDate, Wolters Kluwer Health - 2012-10-19
• Overview of the presentation and classification of acute lymphoblastic leukemia in children 
  Horton TM, Steuber CP
  http://www.uptodate.com/contents/overview-of-the-presentation-and-classification-of-acute-lymphoblas
  UpToDate, Wolters Kluwer Health - 2012-12-08
• Overview of the treatment of acute lymphoblastic leukemia in children 
  Horton TM, Steuber CP
  http://www.uptodate.com/contents/overview-of-the-treatment-of-acute-lymphoblastic-leukemia-in-childr
  UpToDate, Wolters Kluwer Health - 2012-11-21
• Risk group stratification and prognosis for acute lymphoblastic leukemia in children 
  Horton TM, Steuber CP
  http://www.uptodate.com/contents/risk-group-stratification-and-prognosis-for-acute-lymphoblastic-leu
  UpToDate, Wolters Kluwer Health - 2013-04-11
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