TeepuSiddiqueMD, DSc (hc), FAAN

PubMed

• Whole-genome bisulfite sequencing of cell-free DNA unveils age-dependent and ALS-associated methylation alterations.
  Yulin Jin, Karen N Conneely, Wenjing Ma, Robert K Naviaux, Teepu Siddique
  Cell & Bioscience. 2025-02-20
• 3 citations
  Hippocampal aggregation signatures of pathogenic UBQLN2 in amyotrophic lateral sclerosis and frontotemporal dementia.
  Kyrah M Thumbadoo, Birger V Dieriks, Helen C Murray, Molly E V Swanson, Ji Hun Yoo
  Brain. 2024-10-03
• Author Correction: The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration.
  Sarah Opie-Martin, Alfredo Iacoangeli, Simon D Topp, Olubunmi Abel, Keith Mayl
  Nature Communications. 2024-07-02

Journal Articles

• Respiratory Pattern and Tidal Volumes Differ for pressure support and volume-assured pressure support in amyotrophic lateral sclerosis  
  Nicholson TT, Smith SB, Siddique T, Sufit R, Ajroud-Driss S, Coleman JM 3rd, Wolfe LF, Ann Am Thorac Soc, 1/1/2017
• A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis  
  Edens BM, Yan J, Miller N, Deng HX, Siddique T, Ma YC, eLife, 1/1/2017
• Nuclear export of misfolded SOD1 mediaed by a normally buried NES-like sequence reduces proteotoxicity in the nucleus  
  Zhong Y, Wang J, Henderson MJ, Yang P, Hagen BM Siddique T, Vogel BE, Deng HX, Fang S, eLife, 1/1/2017
• Defining SOD1 ALS natural history to guide therapeutic clinical trial design  
  Bali T, Self W, Liu J, Siddique T, Wang LH, Bird TD, Ratti E et al, J Neurol Neurosurg Psychiatry, 1/1/2017
• Early impairment of synaptic and intrinsic excitability in mice expressing ALS/Dementia-linked mutant UBQLN2  
  Radzicki D, Liu E, Deng Hx, Siddique T, Martina M, Front Cell Neuroscience, 1/1/2016
• Identification of TMEM230 mutations in familial Parkinson�s disease  
  Deng HX, Shi Y, Yang Y, Ahmeti KB, Miller N, Huang C, Cheng L, Zhai H, Deng S, Nuytemans K, Corbett NJ, Kim MJ, Deng H, Tang B, Yang Z, Xu Y, Chan P, Huang B, Gao XP, ..., Nature Genetics, 1/1/2016
• Compound heterozygote mutations in SPG7 in afamily with adult-onset primary lateral sclerosis  
  Yi Y, Zhang K, Lynch DR, Lukas T, Ahmeti K, Sleiman PMA, Ryan E, Schadt KA, Newman JH, Deng HX, Siddique N, Siddique T, Neurol Genet, 1/1/2016
• Macular sub-layer thinning and association with pulmonary function tests in Amyotrophic Lateral Sclerosis  
  Simonett J, Huang R, Siddique N, Farsiu S, Siddique T, Volpe N, Fawzi A, Scientific Reports, 1/1/2016
• ACTH (Acthar Gel) Reduces toxic SOD1 protein linked to amyotrophic lateral sclerosis in transgenic mice: A novel observation  
  Arrat H, Lukas TJ, Siddique T, PloS One, 1/1/2015
• Ophthalmic manifestations of amyotrophic lateral sclerosis (An American ophthalmological society thesis)  
  Volpe NJ, Simonett J, Fawzi AA, Siddique T, Trans Am Ophthalmolo Soc, 1/1/2015
• Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogentic connection  
  Wang X, Blanchard J, Grundke-Iqbal I, Wegiel J, Deng HX, Siddique T, Iqbal K, Acta Neuropathology, 1/1/2014
• Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutaitons  
  Fawzi AA, Simonett JM, Purta P, Moss HE, Lowry JL, Deng HX, Siddique N, Sufit R, Bigio EH, Volpe NJ, Siddique T, Amyotroph Lateral Scler Frontotemporal Degener, 1/1/2014
• Sporadic and hereditary amyotrophic lateral sclerosis (ALS)  
  Ajroud-Driss S, Siddique T, Biochim Biophys Acta, 1/1/2014
• A genome-wide association meta-analysis identifies a novel locus at 17q112 associated with sporadic amyotrophic lateral sclerosis  
  Fogh, I et al, Human Molecular Genetics, 1/1/2014
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  Gallardo G, Barowski J, Ravits J, Siddique T, Lingrel JB, Robertson J, Steen H, Bonni A, Nature Neuroscience, 1/1/2014
• Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p341  
  ALSGEN Consortium (Siddique T), Neurobiology of Aging, 1/1/2013
• Effect of prolonged riluzole exposure on cultured motoneurons in a mouse model of ALS  
  Schuster JE, Fu R, Siddique T, Heckman CJ, J Neurophysiolo, 1/1/2012
• Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: Correlating 7 Tesla MRI and pathology  
  Kwan JY, Jeong SY, Van Gelderen P, Deng HX, Quezado MM, Danielian LE, Butman JA, Chen L, Bayat E, Russell J, Siddique T, Duyn JH, Rouault TA, Floeter MK, PLoS One, 1/1/2012
• SIGMAR1 mutations, genetic heterogeneity at the chromosome 9plocus, and the expanding etiological diversity of amyotrophic lateral sclerosis  
  Fecto F, Siddique T, Ann Neurol, 1/1/2011
• Differential involvement of optineurin in amyotrophic lateral sclerosis with or without SOD1 mutations  
  Deng HX, Bigio EH, Zhai H, Fecto F, Ajroud K, Shi Y, Yan J, Mishra M, Ajroud-Driss S, Heller S, Sufit R, Siddique N, Mugnaini E, Siddique T, Archives of Neurology, 1/1/2011
• SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis  
  Fecto F, Yan J, Vemula P, Liu E, Yang Y, Chen W, Zheng JG, Shi Y, Siddique N, Donkervoort D, Ajroud-Driss S, Sufit R, Heller S, Deng HX, Siddique T, Archieves of Neurology (JAMA Neurology), 1/1/2011
• Recent Advances in the Genetics of Hereditary Axonal Sensory-Motor Neuropathies Type 2  
  Ajroud-Driss S, Deng HX, Siddique T, Current Neurol Neurosci Rep, 1/1/2011
• Coordinated age-dependent and pancreatic-specific expression of mouse Reg2Reg2a, and Reg3b genes  
  Wang Y, Jacovetti C, Li B, Siddique T, Xiong X, Yin H, Wang M, Zhao H, Liu JL, Growth Factors, 1/1/2011
• Mutant TRPV4-mediated toxicity is linked to increased constitutive function in axonal neuropathies  
  Fecto F, Shi Y, Huda R, Martina M, Siddique T, Deng HX, Journal of Biological Chemistry, 1/1/2011
• Making Connections: Pathology and Genetics Link Amyotrophic Lateral Sclerosis with Amyotrophic Lateral Sclerosis/Dementia  
  Fecto F, Siddique T, Journal of Molecular Neuroscienc, 1/1/2011
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Books/Book Chapters

• Clinical Genomics: Practical Applications in Adult Patient Care. 
  Chapter: Amyotrophic lateral sclerosis. 
  Page 637 - 640Wallery SS, Fecto F, Siddique TEditors: Stewart DR, Murray MF, Babyatsky MW, Giovanni MA, Alkuraya FS.McGaw Hill and the American College of Physicians2014
• Emery and Rimoin�s Principles and Practice of Medical Genetics 
  Chapter: Motor Neuron Disease 
  Page 1 - 22Siddique T, Deng HX, Ajroud-Driss SEditors: Korf B.Elesevier Ltd.Edition 6th,2013
• Motor Neuron Disease Physical Medicine and Rehabilitation Clinics of North America 
  Chapter: Genetics of Amyotrophic Lateral Sclerosis. 
  Page 429 - 439Siddique N, Siddique TEditors: Weiss, Carter, Kraft.Elsevier Saunders2008
• New Frontiers in Understanding and Treating ALS, Proceedings 
  Chapter: Amyotrophic lateral sclerosis: A triple genetic approach to a three-word disease. 
  Page 33 - 48Siddique TEditors: Suna Kirac Conference on Neurodegeneration Istanbul.2007
• Emery & Rimoin's Principle and Practice of Medical Genetics 
  Chapter: Motor neuron disease. 
  Page 3088 - 3098Siddique T and Gorrie GEditors: Rimoin DL, Connor JM, Pyeritz RE, and Korf BR.Churchill LivingstonEdition 5th,2007
• Neurogenetics: Scientific and Clinical Advances 
  Chapter: Amyotrophic Lateral Sclerosis. 
  Page 693 - 728Siddique T and Dellefave LEditors: Lynch D.Taylor & Francis, New York, NY2005
• Amyotrophic Lateral Sclerosis 
  Chapter: Familial ALS and Genetic Approaches to ALS. 
  Page 141 - 166Siddique T, Dellefave LEditors: Mitsumoto, Przedborski, and Gordon.Taylor & Francis, New York, NY2005
• Neuromuscular Disorders 
  Chapter: Genetic Aspects of Amyotrophic Lateral Sclerosis. 
  Page 21 - 32Siddique T and Lalani IEditors: Pourmand R and Harati Y.Lippincott Williams & Wilkins, Philadelphia, PA2002
• Textbook of Clinical Neurology 
  Chapter: Degenerative Motor, Sensory and Autonomic Disorders. 
  Page 695 - 717Siddique N, Sufit R and Siddique TEditors: Goetz CG, and Pappert J.WB Saunders Company1998
• Current Neurology 
  Chapter: Familial motor neuron disease. 
  Page 281 - 302Siddique T and Hentati AEditors: Appel SH.Mosby-Year Book, Inc., Chicago, IL1996
• Progress and Perspectives in Basic Research and Clinical Application: Proceedings of the 11th Tokyo Metropolitan Institute for Neuroscience (TMIN) International Symposium, October 25-27, 1995 
  Chapter: From the discovery of genetic linkage to chromosome 21 and mutations in SOD1 to the molecular basis of familial amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis. 
  Page 266 - 275Siddique T and Isozumi KEditors: I. Nakano and A. Hirano.Elsevier Science, Netherlands1996
• Cold Spring Harbor Laboratory Symposia on Quantitative Biology: Function & Dysfunction in the Nervous System 
  Chapter: ALS: Molecular clues to the jigsaw puzzle of neuronal degeneration. 
  Page 699 - 708Siddique TCold Spring Harbor Press, Cold Spring Habor, NY1996
• Advances in Neurology, Vol 56 (Amyotrophic lateral sclerosis and other motor neuron diseases) 
  Chapter: Molecular Genetics of Familial Amyotrophic Lateral Sclerosis. 
  Page 227 - 233Siddique TEditors: Rowland LP.Raven Press, New York, NY1991
• Advances in Neurology, Vol. 51 - Alzheimer's Disease. 
  Chapter: Linkage Studies of Late-Onset Familial Alzheimer's Disease. 
  Roses AD, Pericak-Vance MA, Clark CM, Gilbert JR, Yamaoka LH, Haynes CS, Speer MC, Gaskell PC, Hung WY, Trofatter JA, Earl NL, Lee JL, Alberts MJ, Dawson DV, Bartlett ...Raven Press, Ltd., New York, NY1990
• Alzheimer's Disease: Advances in Basic Research and Therapies. 
  Chapter: Linkage Studies in Late Onset Familial Alzheimer's Disease. 
  Page 297 - 310Roses AD, Pericak-Vance MA, Clark CM, Gilbert JR, Yamaoka LH, Haynes CS, Speer MC, Gaskell PC, Hung WY, Trofatter JA, Earl NL, Lee JE, Alberts MJ, Dawson DV, Bartlett ...Editors: Wurtman RJ, Corkin SH, Growdon JH, Ritter-Walker E.1989
• Birth Defects Encyclopedia. 
  Chapter: Amyotrophic Lateral Sclerosis (Sporadic). 
  Siddique TEditors: Buyse, MS.Blackwell Scientific Publications, Inc., Cambridge, MA1989
• Birth Defects Encyclopedia. 
  Chapter: Amyotrophic Lateral Sclerosis, Guam Type. 
  Siddique TEditors: Buyse, MS.Blackwell Scientific Publications, Inc., Cambridge, MA1989
• Birth Defects Encyclopedia. 
  Chapter: Familial Amyotrophic Lateral Sclerosis (Adult and Juvenile). 
  Siddique TEditors: Buyse, MS.Blackwell Scientific Publications, Inc., Cambridge, MA1989
• Birth Defects Encyclopedia. 
  Chapter: Progressive Bulbar Palsy of Childhood (PBPC). 
  Siddique TEditors: Buyse, MS.Blackwell Scientific Publications, Inc., Cambridge, MA1989
• Birth Defects Encyclopedia. 
  Chapter: Susceptibility (Sensitivity) to Polio. 
  Siddique TEditors: Buyse, MS.Blackwell Scientific Publications, Inc., Cambridge, MA1989
• Proceedings of the First International Conference on Alzheimer's Disease and Related Disorders, September 6-9, 1988 
  Chapter: Linkage Studies in Familial Alzheimer's Disease. Alzheimer's Disease and Related Disorders 
  Roses AD, Pericak-Vance MA, Yamaoka LH, Haynes CS, Speer MC, Gaskell PC, Hung WY, Clark CM, Heyman AL, Trofatter JA, Earl NL, Gilbert JR, Lee JE, Alberts MJ, Dawson DV...Editors: Iqbal, H.M. Wisniewski and B. Winblad.Alan R. Liss, Inc., New York, NY1989
• Genetics and Alzheimer's Disease. 
  Chapter: Genetic Linkage Studies in Late-Onset Alzheimer's Disease Families. 
  Page 116 - 123Pericak-Vance MA, Yamaoka LH, Haynes CS, Haines JL, Gaskell PC, Hung WY, Clark CM, Heyman AL, Trofatter JA, Eisenmenger JP, Gilbert JR, Lee JE, Alberts MJ, Speer MC, D...Editors: Sinet, PM, Lamour Y, Christen Y.Springer-Verlag, Berlin, Heidelberg1988
• Familial Alzheimer's Disease: Molecular Genetics and Clinical Perspectives. 
  Chapter: Chap. 7, Linkage Studies in Alzheimer's Disease Families. 
  Page 85 - 97Pericak-Vance MA, Yamaoka LH, Haynes CS, Speer MC, Gaskell PC, Hung WY, CLark CM, Heyman AL, Trofatter JA, Gilbert JR, Lee JE, Alberts MJ, Earl, NL, Dawson DV, Bartlet...Editors: Miner, Richter, Blass, Valentine and Winters-Miner.Marcel Dekker, Inc., New York, NY
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Abstracts/Posters

• Investigation of mouse models for CCHD10 mitochondrial myopathy.
  Ryan E, Caliendo J, Yan J, Deng HX, Siddique T, Musclar Dystropy Association, Arlington, VA, 1/1/2017
• Characterization of transgenic mice expressing ALS-associated CHCHD10-R15L.
  Ryan E, Yan J, Deng HX, Siddique T, Society for Neuroscience, Washington, DC, 1/1/2017
• Molecular dissection of ALS pathogenesis of ubiquilinopathy using CRISPR/Cas9.
  Shi Y, Deng HX, Zhai H, Liu E, Siddique T, Society for Neuroscience; 15th Annual NEALS Meeting, Clearwater Beach, FL, 2016; Washington, DC, 2017, 1/1/2017
• Whole exome sequencing of familial ALS and trios of sporadic ALS to identify new genes associated with ALS.
  Ahmeti K, Ahmeti KB, Yan J, Fecto F, Siddique N, Pericak-Vance M, Deng HX, Siddique T, American Academy of Neurology, Vancouver, Canada, 1/1/2016
• Dominant-negative effect� mechanism in OPTNE478G-linked amyotrophic lateral sclerosis.
  Fecto F, Shi, Y, Esengul YT, Siddique T, Deng HX, American Academy of Neurology, Vancouver, Canada, 1/1/2016
• Demographic and clinical presentation of C9ORF72 (G4C2) expansion mutation from a large familial and sporadic ALS and ALS/FTD North American cohort study.
  Lowry J, Yan J, Siddiqi N, Feiz F, Yang Y Kinsley L, Siddique N, Deng HX, Siddique T, American Academy of Neurology, Vancouver, Canada, 1/1/2016
• Study of intermediate-length polyQ repeats in sporadic and familial amyotrophic lateral sclerosis.
  Nunez-Santans FL, Yan J, Ryan EB, Lowry JL, Siddique N, Siddique T, American Academy of Neurology, Vancouver, Canada, 1/1/2016
• Evaluation of mitochondrial function in CHCHD10 mutation.
  Yan J, Ahmeti KB, Siddique N, Ryan EB, Lukas TJ, Deng HX, Kinsley LM, Yong S, Yang Y, Ma Y, Miller N, Corbett N, Nicholson D, Siddique T, American Academy of Neurology, Vancouver, Canada, 1/1/2016
• Dense core vesicle defect underlies the pathogenesis of ALS5.
  Deng HX, Shi Y, Zhai H, Bigio EH, Siddique N. Siddique T, 15th Annual NEALS Meeting, Clearwater Beach, FL, 1/1/2016
• Fragment analysis identifies atypical C9orf72 (G4C2) expansion electropherogram patterns in a familial and sporadic ALS and ALS/FTD North American cohort study.
  Lowry J, Yan J, Kinsley L, Siddique N, Deng H-X, Siddique T, Society for Neuroscience, Chicago, IL, 1/18/2015
• Etiology-based drug discovery is a route for new amyotrophic lateral sclerosis (ALS) therapeutics.
  Lukas TJ, Arrat H, Siddique T, Society for Neuroscience, Chicago, IL, 1/18/2015
• Analysis of polymorphisms in cbl-c gene for association with sporadic amyotrophic lateral sclerosis in African Americans.
  Nunez-Santana FL, Saeed M, Usacheva EA, Elliott IV D, Siddique N, Siddique T, Society for Neuroscience, Chicago, IL, 1/18/2015
• C9ORF72 Hexanucleotide Repeat Expansion Mutation�Does Size Matter?
  Lowry J, Yan J, Siddique N, Deng H-X, Siddique T, T32 Motor Control Training Day, Northwestern University, Chicago, IL, 1/4/2015
• CHCHD10 was identified as ALS causative gene with complex mechanisms.
  Yan J, Ahmeti KB, Siddique N, Ryan E, Lukas T, Deng HX, Kinsley L, Shi Y, Yang Y, Ma Y, Miller N, Corbett N, Nicholson D, Siddique T, 26th International Symposium on ALS/MND, Orlando, FL, 1/1/2015
• Dominant-negative effect mechanism in OPTNE478G-linked amyotrophic lateral sclerosis.
  Shi Y, Fecto F, Esengul YT, Siddique T, Deng, HX, 26th International Symposium on ALS/MND; Society for Neuroscience, Chicago, IL, 2015; Orlando, FL, 2015, 1/1/2015
• Ubiquilin2 protein interacts with hnRPN family through PXX domain and hnRNPA1 aggregates in sporadic ALS patients.
  Shi Y, Lukas T, Zhai H, Deng HS, Siddique T, 26th International Symposium on ALS/MND; Society for Neuroscience, Chicago, IL, 2015; Orlando, FL, 2015, 1/1/2015
• Genetic analysis of cbl-c gene as a candidate gene for sporadic amyotrophic lateral sclerosis in African Americans.
  Nunez-Santana FL, Saeed M, Usacheva EA, Hentati F, Vasiliev D, Siddique N, Siddique T, ALS/MND, Orlando, FL, 1/1/2015
• CHCHD10 gene mutation causes ALS with complex mechanisms.
  Yan J, Ahmeti K, Siddique N, Ryan EB, Lukas TJ, Deng HX, Kinsley LM, Shi Y, Yang Y, Ma Y, Miller N, Corbett NJ, Nicholson D, Siddique T, Society for Neuroscience, Chicago, IL, 1/1/2015
• Whole exome sequencing identifies novel variants and pathways in ALS.
  Ahmeti KB, Yang Y, Fecto F, Siddique N, Pericak-Vance M, Deng H-X, Siddique T, Society of Neuroscience Annual Meeting, Washington, DC, 1/1/2014
• Mutation in the novel nuclear-encoded mitochondrial protein CHCHD10 in a family with autosomal dominant mitochondrial myopathy.
  Fecto F, Ajroud-Driss S, Ajroud K, Lalani I, Calvo SE, Mootha VK, Deng H-X, Siddique N, Tahmoush AJ, Heiman-Patterson TD, Siddique T, Society of Neuroscience Annual Meeting, Washington, DC, 1/1/2014
• UBQLN2 mutations impair autophagy and cause accumulation of ALS-linked proteins.
  Fecto F, Siddique T, 10th Annual Lewis Landsberg Research Day, Northwestern University, Chicago, IL, 1/1/2014
• Amyloid Properties of Inclusions in ALS and FTLD-TDP but not FTLD-FUS.
  Bigio E, Wu J, Deng HX, Bit-Ivan E, Mao Q, Ganti R, Peterson M, Fecto F, Siddique N, Geula C, Siddique T, Mesulam M, Journal of Neuropathology and Experimental Neurology, Philadelphia, PA, 1/1/2013
• A longitudinal study of diffusion tensor imaging in ALS patients.
  Ajroud-Driss, S, Mansour A, Herrmann K, Casey P, Allen J, Sufit R, Heller Sc, Siddique T, Apkarian A, Neurology; American Academy of Neurology, San Diego, CA, 1/1/2013
• Failure of autolysosome fusion results in impaired autophagy in UBQLN2-linked ALS-FTD.
  Fecto F, Esengul YT, Deng HX, Siddique T, Neurology; American Academy of Neurology, San Diego, CA, 1/1/2013
• Impaired activity of the Ubiquitin-proteasome system in transgenic mice expressing ALS/Dementia-linked mutant UBQLN2.
  Fecto F, Gorrie G, Zhai H, Liu E, Deng HX, Siddique T, Neurology; American Academy of Neurology, San Diego, CA, 1/1/2013
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Lectures

• Amyotrophic lateral sclerosis: How far have we come? 
  Montefore Medical Center/Albert Einstein College of Medicine, New York, NY - 1/1/2018
• Genetic pleomorphism in ALS; the expanding phenotype. 
  University of Chicago, Chicago, IL - 1/1/2017
• ALS: The black box of neurodegeneration and how it was pried open by neurogenetics. 
  Northwestern University Feinberg School of Medicine, Chicago, IL - 1/1/2017
• Con: Stem cell therapies are not ready for human clinical trial. 
  Dublin, Ireland - 1/1/2016
• What is amyotrophic lateral sclerosis (ALS) 
  Kissimmee, FL - 1/1/2015
• Apolipoproteins including Apol1 and ALS. 
  Hyattsville, MD - 1/1/2015
• Special Interest Group: Neuromuscular Disorders. 
  Chicago, IL - 1/1/2015
• Amyotrophic lateral sclerosis: Advances in the understanding of neurodegeneration. 
  Baylor University Medical Center, Dallas, TX - 1/1/2015
• ALS: etiologies, topographies and pathogeneses in neurodegeneration 
  University of South Carolina, Charleston, SC - 1/1/2014
• Towards forging a synthesis in the pathogenesis of ALS 
  Medical College of Wisconsin - 1/1/2014
• Insights into mechanism of disease in ALS based on etiologic factors. Genetics of ALS. 
  Minneapolis, MN - 1/1/2014
• Is neurodegeneration a consequence of proteins in evolutionary conflict. Development and Evolution of the Human Motor System in Relation to ALS and FTD. 
  Banbury Center of Cold Spring Harbor, Long Island, NY - 1/1/2013
• Understanding human ALS at the molecular level. 
  University of Chicago, Chicago, IL - 1/1/2013
• New Drug Targets for ALS 
  Benedictine University, Lisle, IL - 1/1/2012
• Bringing neurodegeneration to heel: Lessons for Lou Gehrig�s disease. 
  Lake Forest College, Lake Forest, IL - 1/1/2012
• What ALS can tell about topography and molecular pathology of neurodegeneration. 
  Rehabilitaiton Institute of Chicago, Chicago, IL - 1/1/2012
• Cellular Recycling Pathways in ALS and FTD. 
  Philadelphia, PA - 1/1/2012
• Cause of mechanism: the molecular funnel of neurodegeneration. 
  Dublin, Irleand - 1/1/2012
• ALS: A Ubiquilinopathy. 
  Seattle, WA - 1/1/2012
• Novel insights in ALS and ALS/dementia. 
  Columbia University, New York, NY - 1/1/2011
• Science & Religion: Aspects of Human Experience 
  Illinois Institute of Technology, Chicago, IL - 1/1/2011
• Role of Ubiquilin2 in the convergence of molecular pathology in ALS and ALS/dementia. 
  Chicago, IL - 1/1/2011
• Identifing a common cause of ALS. 
  Chicago, IL - 1/1/2011
• Lou Gehrig and Chairman Mao: a fatal link 
  East West University, Chicago, IL - 1/1/2011
• Lessons from the Genetic Pathology of Amyotrophic lateral sclerosis. 
  University of Chicago, Chicago, IL - 1/1/2010
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Other

• Amyotrophic lateral Sclerosis Overview. In: Pagon RA, Bird TD, Dolan CR, Stephens K. Adam MP editors. 
  Kinsley L., Siddique T, Gene Reviews
  University of Washington, Seattle, WA - 1/1/2015
• Amyotrophic Lateral Sclerosis Overview. (Pagon RA, Bird TC, Dolan CR, Stephens K, eds) 
  Donkervoort S, Siddique T, Gene Reviews
  University of Washington, Seattle, WA - 1/1/2009