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Office
1470 Madison Avenue
Mount Sinai Hospital Ruttenberg Treatment Center
New York, NY 10029Phone+1 212-241-6756Fax+1 212-860-7186
Education & Training
University at BuffaloResidency, Internal Medicine, 1960 - 1961
New York Medical College (Metropolitan)Residency, Internal Medicine, 1959 - 1960
Lincoln Medical and Mental Health CenterInternship, Transitional Year, 1958 - 1959
Tohoku University Faculty of MedicineClass of 1957
Certifications & Licensure
ME State Medical License 1963 - 2021
NY State Medical License 1968 - 2020
Clinical Trials
- Safety of ON 01910.Na and Irinotecan or ON 01910.Na and Oxaliplatin in Patients With Hepatoma Start of enrollment: 2008 Jun 01
- Safety of ON 01910.Na as a 3-day Infusion in Patients With Advanced Cancer Start of enrollment: 2006 Aug 01
Publications & Presentations
PubMed
- 18 citationsPhase 1 study of intravenous rigosertib (ON 01910.Na), a novel benzyl styryl sulfone structure producing G2/M arrest and apoptosis, in adult patients with advanced can...Takao Ohnuma, D. Lehrer, Ren C, S. Y. Cho, Manoj Maniar
American Journal of Cancer Research. 2013-06-20 - 30 citationsEffect of ON 01910.Na, an Anticancer Mitotic Inhibitor, on Cell-Cycle Progression Correlates with RanGAP1 HyperphosphorylationIrina Oussenko, James F. Holland, E. Premkumar Reddy, Takao Ohnuma
Cancer Research. 2011-07-15 - 3 citationsDiscontinuous drug binding to proteins: binding of an antineoplastic benzyl styryl sulfone to albumin and enzymes in vitro and in phase I clinical trials.Sool Yeon Cho, Takao Ohnuma, Lewis R. Silverman, James F. Holland, John Roboz
Drug Metabolism and Disposition. 2010-09-01
Committees
- member, P & T Committee
Professional Memberships
- Member
- Member
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