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Office
40 Duke Medicine Cir
Durham, NC 27710Phone+1 919-681-1300
Summary
- I take care of patients with pulmonary hypertension (PH). I also research signaling pathways that are altered in the development of PH in rodent models of the disease. PH covers a wide spectrum of diseases, from the rare pulmonary arterial hypertension (prevalence of 15 in one million) to complications of more common heart and lung disease. PH typically leads to complications through its effects on the heart, leading to heart failure. At the Duke Pulmonary Vascular Disease Center, we see a number of patients with PH and offer all available therapies, including continuous intravenous infusion, inhaled therapies, and surgical options.
Education & Training
- Duke University HospitalFellowship, Cardiovascular Disease, 2008 - 2013
- Duke University HospitalResidency, Internal Medicine, 2006 - 2008
- University of Chicago Division of the Biological Sciences The Pritzker School of MedicineClass of 2006
- University of ChicagoPh.D., Biochemistry and Molecular Biology, 2006
- The College, The University of ChicagoB.S., Chemistry, with General and Departmental Honors, 1994 - 1998
Certifications & Licensure
- NC State Medical License 2009 - 2025
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Cardiovascular Disease
Awards, Honors, & Recognition
- Chair’s Award Department of Medicine, Duke University Medical Center, 2013
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
- Joseph C. Greenfield, Jr., MD Scholar in Cardiology Division of Cardiology, Duke University Medical Cente, 2012
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Clinical Trials
- Assessing Response to Inhaled Prostacyclin With Hyperpolarized Xe MRI Start of enrollment: 2018 Mar 29
- Pulmonary Hypertension SOLAR Start of enrollment: 2023 Nov 08
Publications & Presentations
PubMed
- 1 citationsEmerging multimodality imaging techniques for the pulmonary circulation.Sudarshan Rajagopal, Harm J Bogaard, Mohammed S M Elbaz, Benjamin H Freed, Martine Remy-Jardin
The European Respiratory Journal. 2024-10-01 - Phosphorylation patterns in the AT1R C-terminal tail specify distinct downstream signaling pathways.Clarice Gareri, Conrad T Pfeiffer, Xue Jiang, Joao A Paulo, Steven P Gygi
Science Signaling. 2024-08-13 - 8 citationsG Protein-Coupled Receptors: A Century of Research and Discovery.Samuel Liu, Preston J Anderson, Sudarshan Rajagopal, Robert J Lefkowitz, Howard A Rockman
Circulation Research. 2024-06-21
Journal Articles
- A Protocol for Quantifying Cardiogenic Oscillations in Dynamic 129Xe Gas Exchange Spectroscopy: The Effects of Idiopathic Pulmonary FibrosisSudarshan Rajagopal, Craig Rackley, Joseph G Mammarappallil, H Page McAdams, NMR in Biomedicine
Abstracts/Posters
- Beta-arrestins regulate signaling by the type II bone morphogenetic protein receptor in pulmonary arterial hypertension.Rajagopal S, Duke Cardiovascular Symposium, Durham, NC., 5/24/2010
- Beta-arrestins regulate signaling by bone morphogenetic protein receptor 2 in pulmonary arterial hypertension.Rajagopal S, American Society for Clinical Investigation Annual Meeting, Chicago, IL., 4/23/2010
- Total Chemical Synthesis of a Minimal Isoform of a Potassium Channel Regulatory Subunit.Rajagopal S, American Society for Clinical Investigation, Chicago, IL., 5/1/2006
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Lectures
- Beta-arrestins Regulate Signaling by Type II Bone Morphogenetic Protein Receptor in Pulmonary Arterial Hypertension.American College of Cardiology, New Orleans, LA. - 4/3/2011
- G proteins, Beta Arrestins and the Role of Hypoxia in Adrenergic Signaling.17th International Hypoxia Symposium, Lake Louise, Canada. - 2/17/2011
- Beta-arrestin- but not G protein-mediated Signaling by the "Decoy" Receptor CXCR7.Columbia University Division of Preventive Medicine and Nutrition Seminar Series. - 10/14/2009
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Press Mentions
- Ethics of Genome Editing: Avoiding False EquivalenciesFebruary 25th, 2019
Professional Memberships
- Fellow
- Member
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