Dr. Orkin is on Doximity
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Office
1 Blackfan Circle
Karp Researcg Bldg
Boston, MA 02115Phone+1 617-919-2042Fax+1 617-730-0222
Education & Training
- Boston Children’s Hospital/Boston Medical CenterFellowship, Pediatric Hematology/Oncology, 1976 - 1978
- Boston Children’s Hospital/Boston Medical CenterResidency, Pediatrics, 1975 - 1976
- Childrens HospitalInternship, Transitional Year, 1972 - 1973
- Harvard Medical SchoolClass of 1972
Certifications & Licensure
- MA State Medical License 1978 - 2025
- American Board of Pediatrics Pediatrics
Awards, Honors, & Recognition
- Elected Member Institute of Medicine, 1992
- Elected Member The American Society for Clinical Investigation, 1982
- Investigator Howard Hughes Medical Institute
Publications & Presentations
PubMed
- Redirecting E3 Ubiquitin Ligases for Targeted Protein Degradation with Heterologous Recognition Domains.Huan Yang, Ge Zheng, Grace Y Li, Alia Alshaye, Stuart H Orkin
The Journal of Biological Chemistry. 2024-12-13 - Gene editing without ex vivo culture evades genotoxicity in human hematopoietic stem cells.Jing Zeng, My Anh Nguyen, Pengpeng Liu, Lucas Ferreira da Silva, Sébastien Levesque
Cell Stem Cell. 2024-12-11 - 1 citationsStructural insights into the DNA-binding mechanism of BCL11A: The integral role of ZnF6.Thibault Viennet, Maolu Yin, Abhilash Jayaraj, Woojin Kim, Zhen-Yu J Sun
Structure. 2024-12-05
Press Mentions
- HMN 2024: How Could a Pill Replace Gene Therapy for Sickle Cell Disease?December 20th, 2024
- The Power and Potential of Gene TuningAugust 12th, 2024
- Gale and Ira Drukier Prize in Children’s Health Research Awarded to Johns Hopkins Medicine Infectious Disease SpecialistNovember 3rd, 2022
- Join now to see all
Grant Support
- Gfi-Proteins In Hematopoietic DevelopmentNational Heart, Lung, And Blood Institute2004–2012
- Molecular Analysis Of Normal And Thalassemic DNANational Heart, Lung, And Blood Institute1989–2012
- Hemoglobin Switching: Genetics To TranslationNational Heart, Lung, And Blood Institute2011
- Human Pluripotent Stem Cell And Progenitor Models Of Cardiac And Blood DiseasesNational Heart, Lung, And Blood Institute2009–2011
- Research Training In Pediatric OncologyNational Cancer Institute2009–2011
- Exploiting Mouse Models Of Pediatric Cancers And Epigenetics For TherapyNational Cancer Institute2009–2011
- Developmental Biology Of Human ErythropoiesisNational Heart, Lung, And Blood Institute2006–2011
- A Center Of Molecular Developmental HematopoiesisNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2011
- Extending GWAS At The BCL11A Locus To Novel Therapeutics For Hbf InductionNational Heart, Lung, And Blood Institute2009–2010
- Genetic Approaches To Hemoglobin SwitchingNational Heart, Lung, And Blood Institute2006–2010
- Modeling Childhood TEL-AML1 (RUNX1)National Cancer Institute2006–2010
- Center Of Molecular Developmental HematopoiesisNational Institute Of Diabetes And Digestive And Kidney Diseases2005–2008
- Systems Analysis Of Cancer Pathways In Mouse ModelsNational Cancer Institute2005–2008
- Administrative CoreNational Institute Of Diabetes And Digestive And Kidney Diseases2007
- Administrative Core And Enrichment ProgramNational Institute Of Diabetes And Digestive And Kidney Diseases2005
- Molecular Mechanisms Of Tissue Stem Cell PlasticityNational Heart, Lung, And Blood Institute2001–2004
- Hematopoiesis In NF E2 Gene Targeted ES CellsNational Heart, Lung, And Blood Institute1999–2003
- Core--Mouse Embryonic Stem Cell And Gene TargetingNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2002
- Transcription Factor GATA-1 In Terminal Erythroid DevelopmentNational Heart, Lung, And Blood Institute1996–2002
- Training Grant In GeneticsNational Institute Of General Medical Sciences1994–2000
- Role Of Bhlh Protein SCL In Hematopoietic DevelopmentNational Institute Of Diabetes And Digestive And Kidney Diseases1997–1998
- Core--Embryonic Stem Tissue Culture And Mouse CoreNational Institute Of Diabetes And Digestive And Kidney Diseases1997–1998
- Center For Molecular Development HematopoiesisNational Institute Of Diabetes And Digestive And Kidney Diseases1994–1998
- Hematopoiesis In NF-E2 Gene-Targeted ES CellsNational Heart, Lung, And Blood Institute1994–1998
- Structure-Function Analysis Of Specific Human GenesEunice Kennedy Shriver National Institute Of Child Health &Human Development1989–1997
- Molecular Developmental HematopoiesisNational Institute Of Diabetes And Digestive And Kidney Diseases1993
- GeneticsNational Institute Of General Medical Sciences1989–1993
- Asip-Children'S Hospital-BostonNational Institute Of Mental Health1992
- Structure Function Analysis Of Specific Human GenesEunice Kennedy Shriver National Institute Of Child Health &Human Development1988
- Molecular Analysis Of Normal And Tyhalassemic DNANational Heart, Lung, And Blood Institute1985–1988
- Gordon Research Conference On Molecular GeneticsNational Institute Of General Medical Sciences1987
- Structure-Function Analysis Of Specific Human GenesEunice Kennedy Shriver National Institute Of Child Health &Human Development1985–1987
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