StuartALiptonMDPhD

Professor and Founding Director, Neurodegeneration New Medicines Center, Step Family Foundation Endowed Chair, Scripps Research; Professor of Neurology/Neurosciences (adj), UC San Diego School of Medicine & Yale School of Medicine. Previously: Asst., Assoc, Prof., Department of Neurology, Harvard Medical School; Director, CNS Research Institute, Brigham and Women's Hospital, Boston, Massachusetts

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Office
4510 Executive Dr
Ste 325
San Diego, CA 92121
Phone+1 858-657-8540

Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Neurology, 1978 - 1981
Beth Israel Deaconess Medical CenterInternship, Internal Medicine, 1977 - 1978
Perelman School of Medicine at the University of PennsylvaniaClass of 1977

Certifications & Licensure

CA State Medical License 1999 - 2027
MA State Medical License 1981 - 2025
ME State Medical License Active through 1988
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Member AAAS, Neuroscience section, 2011
Awardee Ernst Jung Prize in Medicine, 2004
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013

Publications & Presentations

PubMed

Redox regulation, protein S-nitrosylation, and synapse loss in Alzheimer's and related dementias.
Chang-Ki Oh, Tomohiro Nakamura, Xu Zhang, Stuart A Lipton
Neuron. 2024-12-04
Using in vivo intact structure for system-wide quantitative analysis of changes in proteins.
Ahrum Son, Hyunsoo Kim, Jolene K Diedrich, Casimir Bamberger, Daniel B McClatchy
Nature Communications. 2024-10-29
1 citations
Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids.
Dorit Trudler, Swagata Ghatak, Michael Bula, James Parker, Maria Talantova
Molecular Psychiatry. 2024-09-30

Press Mentions

SNO-Y Protein Levels Help Explain Why More Women Develop Alzheimer’sJanuary 6th, 2023
Beer, Dolphins and More Discoveries That Could Shed Light on Alzheimer’s DiseaseDecember 22nd, 2022
Brain Protein Offers Clues About Higher Risk in WomenDecember 17th, 2022
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Grant Support

Project II - Clinically-Safe Nmdar Antagonists Prevent NeurotoxicityEunice Kennedy Shriver National Institute Of Child Health &Human Development2012
Core A - Administrative And Statistical ComponentsEunice Kennedy Shriver National Institute Of Child Health &Human Development2012
Cellular/Molecular Pathophysiology Of Intellectual And Developmental DisabilitiesEunice Kennedy Shriver National Institute Of Child Health &Human Development2012
LA Jolla Interdisciplinary Neuroscience Center CoresNational Institute Of Neurological Disorders And Stroke2011
Administrative Core (SBMRI)National Institute Of Neurological Disorders And Stroke2011
Clinically-Safe Nmdar Antagonists Prevent NeurotoxicityEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
Administrative/Neuroscience CoresEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
Project 3: S-Nitrosylation Affects Protein Misfolding And Contributes To ParkinsoNational Institute Of Environmental Health Sciences2010–2011
LA Jolla-Parkinson'S Disease Center GrantNational Institute Of Environmental Health Sciences2010–2011
Core F: Research Development CoreNational Institute Of Environmental Health Sciences2010–2011
Administrative /Biostatistical CoreNational Institute Of Environmental Health Sciences2010–2011
Cellular/Molecular Pathophysiology Of Mental RetardationEunice Kennedy Shriver National Institute Of Child Health &Human Development2010–2011
LA Jolla Interdisciplinary Neuroscience Center Cores - Vital VNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Structural BIO Core SalkNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Structural BIO Core BUNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Stem Cell Core BUNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - SalkNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core Tsri SAT SiteNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core SalkNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core BUNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Nueropathology Core UCSDNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Molecular Imaging Hist CORNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Htca CoreNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Gene Core SalkNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Gene Analysis Core BUNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Electro Core SalkNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Electro Core BUNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Chemical CoreNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Burnham AdminNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Bioinfo Core SalkNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center Cores - BIO Info Core BUNational Institute Of Neurological Disorders And Stroke2010
LA Jolla Interdisciplinary Neuroscience Center CoresNational Institute Of Neurological Disorders And Stroke2010
Retinal Ganglion Cells: Ion Channels &TransmittersNational Eye Institute2010
LA Jolla Interdisciplinary Neuroscience Center Cores - Vital VNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Structural BIO Core SalkNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Structural BIO Core BUNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Stem Cell Core BUNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - SalkNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core Tsri SAT SiteNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core SalkNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core BUNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Nueropathology Core UCSDNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Molecular Imaging Hist CORNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Htca CoreNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Gene Core SalkNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Gene Analysis Core BUNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Electro Core SalkNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Electro Core BUNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Chemical CoreNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Burnham AdminNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - Bioinfo Core SalkNational Institute Of Neurological Disorders And Stroke2009
LA Jolla Interdisciplinary Neuroscience Center Cores - BIO Info Core BUNational Institute Of Neurological Disorders And Stroke2009
Project 3: S-Nitrosylation Affects Protein Misfolding And Contributes To ParkinsoNational Institute Of Environmental Health Sciences2008–2009
LA Jolla-Parkinson'S Disease Center GrantNational Institute Of Environmental Health Sciences2008–2009
Core F: Research Development CoreNational Institute Of Environmental Health Sciences2008–2009
Administrative /Biostatistical CoreNational Institute Of Environmental Health Sciences2008–2009
Erythropoietin PLUS Igf-In Neuroprotection From AIDSNational Institute Of Neurological Disorders And Stroke2007–2009
LA Jolla Interdisciplinary Neuroscience Center CoresNational Institute Of Neurological Disorders And Stroke2006–2009
Retinal Ganglion Cells: Ion Channels &TransmittersNational Eye Institute2006–2009
Aids-Related Neurotoxicity And Novel Nmdar AntagonistsNational Eye Institute2005–2009
Clinically-Safe Nmdar Antagonists Prevent NeurotoxicityEunice Kennedy Shriver National Institute Of Child Health &Human Development2005–2009
Cellular/Molecular Pathophysiology Of Mental RetardationEunice Kennedy Shriver National Institute Of Child Health &Human Development1999–2009
Neurodegenerative Effects Of Botulinum ToxinsNational Institute Of Allergy And Infectious Diseases2004–2008
Neuroscience Research CoreEunice Kennedy Shriver National Institute Of Child Health &Human Development2007
S-Nitrosylation Of Matrix Metalloproteinases In AIDSNational Institute Of Neurological Disorders And Stroke2004–2007
Caspase Cleavage Of MEF2 Mediates Neuronal ApoptosisNational Institute Of Neurological Disorders And Stroke2003–2007
EPO PLUS IGF-I In Neuroprotection From AIDSNational Institute Of Neurological Disorders And Stroke2005–2006
Administrative/Neuroscience CoresEunice Kennedy Shriver National Institute Of Child Health &Human Development2005
Erythropoietin-Induced NeuroprotectionNational Institute Of Neurological Disorders And Stroke2002–2005
EPO PLUS Igf-In Neuroprotection From AIDSNational Institute Of Neurological Disorders And Stroke2004
Retinal Ganglion Cells--Ion Channels &TransmittersNational Eye Institute2000–2004
Neurobiology Of Disease -- Teaching WorkshopNational Institute Of Neurological Disorders And Stroke2001–2003
Chemokines And Macrophages In HIV Neuronal ApoptosisNational Institute Of Neurological Disorders And Stroke2001–2003
Aids-Related Neurotoxcity: GP120 And ChemokinesNational Eye Institute2000–2003
Developmental CoreNational Institute Of Mental Health2001–2002
HIV Associated Neurotoxicity And NMDA AntagonistsEunice Kennedy Shriver National Institute Of Child Health &Human Development1999–2002
Core--Neuroscience ResearchEunice Kennedy Shriver National Institute Of Child Health &Human Development1999–2002
Clinically SAFE NMDA Antagonists Prevent NeurotoxicityEunice Kennedy Shriver National Institute Of Child Health &Human Development1996–2002
Neurobiology Of Disease Teaching WorkshopsNational Institute Of Neurological Disorders And Stroke2000
Retinal Ganglion Cells--Ion Channels And TransmittersNational Eye Institute1999
AIDS Related Neurotoxicity GP120 And NMDA AntagonistsNational Eye Institute1999
AIDS Related Neurotoxicity GP120 And ChemokinesNational Eye Institute1999
Retinal Ganglion Cells--Ion Channels And TransmittersNational Eye Institute1997–1998
AIDS Related Neurotoxicity GP120 And NMDA AntagonistsNational Eye Institute1997–1998
Cellular/Molecular Pathophysiology Of Mental RetardationEunice Kennedy Shriver National Institute Of Child Health &Human Development1997
Core--Neuroscience CoreEunice Kennedy Shriver National Institute Of Child Health &Human Development1996–1997
Clinically SAFE NMDA Antagonists Prevent NeurotoxicityEunice Kennedy Shriver National Institute Of Child Health &Human Development1996–1997
AIDS Related Neurotoxicity GP120 And NMDA AntagonistsNational Eye Institute1995–1997
Retinal Ganglion Cells--Ion Channels And TransmittersNational Eye Institute1994–1997
Cellular/Molecular Pathophysiology Of Mental RetardationEunice Kennedy Shriver National Institute Of Child Health &Human Development1992–1997
Ca++ Channel Antagonists And Aids-Related NeurotoxicityNational Eye Institute1994
Thy-1 And Neurite Regeneration By Retinal Ganglion CellsNational Eye Institute1986–1994
Retinal Ganglion Cells: Ion Channels &TransmittersNational Eye Institute1991–1993
CA2+ Channel Antagonists And Aids-Related NeurotoxicityNational Eye Institute1991–1993
Developmental NeurologyNational Institute Of Neurological Disorders And Stroke1988–1993
Retinal Ganglion Cells--Ion Channels &TransmittersNational Eye Institute1988–1990
Communication And Regeneration Of CNS NeuritesNational Institute Of Neurological Disorders And Stroke1985–1988
Retinal Ganglion Cells: Ion Channel &TransmittersNational Eye Institute1987
RAT Retinal Ganglion Cells: Ion Channels &TransmittersNational Eye Institute1985–1986

Other Languages

Spanish

Industry Relationships

Scientific Advisory Board Member, Eli LillyMember of Neuroscience SABDisclosure: Consultancy payment2015 - Present
Scientific Founder, ADAMAS Pharmaceuticals, Inc.Scientific Co-FounderDisclosure: Equity2000 - Present