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Office
4510 Executive Dr
Ste 325
San Diego, CA 92121Phone+1 858-657-8540
Education & Training
- Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Neurology, 1978 - 1981
- Beth Israel Deaconess Medical CenterInternship, Internal Medicine, 1977 - 1978
- Perelman School of Medicine at the University of PennsylvaniaClass of 1977
Certifications & Licensure
- CA State Medical License 1999 - 2025
- MA State Medical License 1981 - 2025
- ME State Medical License Active through 1988
- American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- Member AAAS, Neuroscience section, 2011
- Awardee Ernst Jung Prize in Medicine, 2004
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013
Publications & Presentations
PubMed
- 420 citationsNitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activityDongdong Yao, Zezong Gu, Tomohiro Nakamura, Zhong Qing Shi, Yuliang Ma
Proceedings of the National Academy of Sciences of the United States of America. 2004-07-20 - 853 citationsS-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal InjuryDong-Hyung Cho, Tomohiro Nakamura, Jianguo Fang, Piotr Cieplak, Adam Godzik
Science. 2009-04-03 - 325 citationsMolecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation.Yun-Beom Choi, Lalitha Tenneti, Dean A. Le, Justin Ortiz, Guang Bai
Nature Neuroscience. 2000-01-01
Press Mentions
- SNO-Y Protein Levels Help Explain Why More Women Develop Alzheimer’sJanuary 6th, 2023
- Beer, Dolphins and More Discoveries That Could Shed Light on Alzheimer’s DiseaseDecember 22nd, 2022
- Brain Protein Offers Clues About Higher Risk in WomenDecember 17th, 2022
- Join now to see all
Grant Support
- Project II - Clinically-Safe Nmdar Antagonists Prevent NeurotoxicityEunice Kennedy Shriver National Institute Of Child Health &Human Development2012
- Core A - Administrative And Statistical ComponentsEunice Kennedy Shriver National Institute Of Child Health &Human Development2012
- Cellular/Molecular Pathophysiology Of Intellectual And Developmental DisabilitiesEunice Kennedy Shriver National Institute Of Child Health &Human Development2012
- LA Jolla Interdisciplinary Neuroscience Center CoresNational Institute Of Neurological Disorders And Stroke2011
- Administrative Core (SBMRI)National Institute Of Neurological Disorders And Stroke2011
- Clinically-Safe Nmdar Antagonists Prevent NeurotoxicityEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
- Administrative/Neuroscience CoresEunice Kennedy Shriver National Institute Of Child Health &Human Development2011
- Project 3: S-Nitrosylation Affects Protein Misfolding And Contributes To ParkinsoNational Institute Of Environmental Health Sciences2010–2011
- LA Jolla-Parkinson'S Disease Center GrantNational Institute Of Environmental Health Sciences2010–2011
- Core F: Research Development CoreNational Institute Of Environmental Health Sciences2010–2011
- Administrative /Biostatistical CoreNational Institute Of Environmental Health Sciences2010–2011
- Cellular/Molecular Pathophysiology Of Mental RetardationEunice Kennedy Shriver National Institute Of Child Health &Human Development2010–2011
- LA Jolla Interdisciplinary Neuroscience Center Cores - Vital VNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Structural BIO Core SalkNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Structural BIO Core BUNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Stem Cell Core BUNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - SalkNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core Tsri SAT SiteNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core SalkNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core BUNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Nueropathology Core UCSDNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Molecular Imaging Hist CORNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Htca CoreNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Gene Core SalkNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Gene Analysis Core BUNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Electro Core SalkNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Electro Core BUNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Chemical CoreNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Burnham AdminNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Bioinfo Core SalkNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - BIO Info Core BUNational Institute Of Neurological Disorders And Stroke2010
- LA Jolla Interdisciplinary Neuroscience Center CoresNational Institute Of Neurological Disorders And Stroke2010
- Retinal Ganglion Cells: Ion Channels &TransmittersNational Eye Institute2010
- LA Jolla Interdisciplinary Neuroscience Center Cores - Vital VNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Structural BIO Core SalkNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Structural BIO Core BUNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Stem Cell Core BUNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - SalkNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core Tsri SAT SiteNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core SalkNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - PRO Core BUNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Nueropathology Core UCSDNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Molecular Imaging Hist CORNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Htca CoreNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Gene Core SalkNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Gene Analysis Core BUNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Electro Core SalkNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Electro Core BUNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Chemical CoreNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Burnham AdminNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - Bioinfo Core SalkNational Institute Of Neurological Disorders And Stroke2009
- LA Jolla Interdisciplinary Neuroscience Center Cores - BIO Info Core BUNational Institute Of Neurological Disorders And Stroke2009
- Project 3: S-Nitrosylation Affects Protein Misfolding And Contributes To ParkinsoNational Institute Of Environmental Health Sciences2008–2009
- LA Jolla-Parkinson'S Disease Center GrantNational Institute Of Environmental Health Sciences2008–2009
- Core F: Research Development CoreNational Institute Of Environmental Health Sciences2008–2009
- Administrative /Biostatistical CoreNational Institute Of Environmental Health Sciences2008–2009
- Erythropoietin PLUS Igf-In Neuroprotection From AIDSNational Institute Of Neurological Disorders And Stroke2007–2009
- LA Jolla Interdisciplinary Neuroscience Center CoresNational Institute Of Neurological Disorders And Stroke2006–2009
- Retinal Ganglion Cells: Ion Channels &TransmittersNational Eye Institute2006–2009
- Aids-Related Neurotoxicity And Novel Nmdar AntagonistsNational Eye Institute2005–2009
- Clinically-Safe Nmdar Antagonists Prevent NeurotoxicityEunice Kennedy Shriver National Institute Of Child Health &Human Development2005–2009
- Cellular/Molecular Pathophysiology Of Mental RetardationEunice Kennedy Shriver National Institute Of Child Health &Human Development1999–2009
- Neurodegenerative Effects Of Botulinum ToxinsNational Institute Of Allergy And Infectious Diseases2004–2008
- Neuroscience Research CoreEunice Kennedy Shriver National Institute Of Child Health &Human Development2007
- S-Nitrosylation Of Matrix Metalloproteinases In AIDSNational Institute Of Neurological Disorders And Stroke2004–2007
- Caspase Cleavage Of MEF2 Mediates Neuronal ApoptosisNational Institute Of Neurological Disorders And Stroke2003–2007
- EPO PLUS IGF-I In Neuroprotection From AIDSNational Institute Of Neurological Disorders And Stroke2005–2006
- Administrative/Neuroscience CoresEunice Kennedy Shriver National Institute Of Child Health &Human Development2005
- Erythropoietin-Induced NeuroprotectionNational Institute Of Neurological Disorders And Stroke2002–2005
- EPO PLUS Igf-In Neuroprotection From AIDSNational Institute Of Neurological Disorders And Stroke2004
- Retinal Ganglion Cells--Ion Channels &TransmittersNational Eye Institute2000–2004
- Neurobiology Of Disease -- Teaching WorkshopNational Institute Of Neurological Disorders And Stroke2001–2003
- Chemokines And Macrophages In HIV Neuronal ApoptosisNational Institute Of Neurological Disorders And Stroke2001–2003
- Aids-Related Neurotoxcity: GP120 And ChemokinesNational Eye Institute2000–2003
- Developmental CoreNational Institute Of Mental Health2001–2002
- HIV Associated Neurotoxicity And NMDA AntagonistsEunice Kennedy Shriver National Institute Of Child Health &Human Development1999–2002
- Core--Neuroscience ResearchEunice Kennedy Shriver National Institute Of Child Health &Human Development1999–2002
- Clinically SAFE NMDA Antagonists Prevent NeurotoxicityEunice Kennedy Shriver National Institute Of Child Health &Human Development1996–2002
- Neurobiology Of Disease Teaching WorkshopsNational Institute Of Neurological Disorders And Stroke2000
- Retinal Ganglion Cells--Ion Channels And TransmittersNational Eye Institute1999
- AIDS Related Neurotoxicity GP120 And NMDA AntagonistsNational Eye Institute1999
- AIDS Related Neurotoxicity GP120 And ChemokinesNational Eye Institute1999
- Retinal Ganglion Cells--Ion Channels And TransmittersNational Eye Institute1997–1998
- AIDS Related Neurotoxicity GP120 And NMDA AntagonistsNational Eye Institute1997–1998
- Cellular/Molecular Pathophysiology Of Mental RetardationEunice Kennedy Shriver National Institute Of Child Health &Human Development1997
- Core--Neuroscience CoreEunice Kennedy Shriver National Institute Of Child Health &Human Development1996–1997
- Clinically SAFE NMDA Antagonists Prevent NeurotoxicityEunice Kennedy Shriver National Institute Of Child Health &Human Development1996–1997
- AIDS Related Neurotoxicity GP120 And NMDA AntagonistsNational Eye Institute1995–1997
- Retinal Ganglion Cells--Ion Channels And TransmittersNational Eye Institute1994–1997
- Cellular/Molecular Pathophysiology Of Mental RetardationEunice Kennedy Shriver National Institute Of Child Health &Human Development1992–1997
- Ca++ Channel Antagonists And Aids-Related NeurotoxicityNational Eye Institute1994
- Thy-1 And Neurite Regeneration By Retinal Ganglion CellsNational Eye Institute1986–1994
- Retinal Ganglion Cells: Ion Channels &TransmittersNational Eye Institute1991–1993
- CA2+ Channel Antagonists And Aids-Related NeurotoxicityNational Eye Institute1991–1993
- Developmental NeurologyNational Institute Of Neurological Disorders And Stroke1988–1993
- Retinal Ganglion Cells--Ion Channels &TransmittersNational Eye Institute1988–1990
- Communication And Regeneration Of CNS NeuritesNational Institute Of Neurological Disorders And Stroke1985–1988
- Retinal Ganglion Cells: Ion Channel &TransmittersNational Eye Institute1987
- RAT Retinal Ganglion Cells: Ion Channels &TransmittersNational Eye Institute1985–1986
Other Languages
- Spanish
Industry Relationships
- Scientific Advisory Board Member, Eli LillyMember of Neuroscience SABDisclosure: Consultancy payment2015 - Present
- Scientific Founder, ADAMAS Pharmaceuticals, Inc.Scientific Co-FounderDisclosure: Equity2000 - Present
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