StevenJonRussellMDPhD

Endocrinology • Boston, MA

Diabetes, Lipid Metabolism

Associate Professor, Medicine - Massachusetts General Hospital, Harvard Medical School

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Office
MGH Diabetes Research Center
50 Staniford Street, Suite 340
Boston, MA 02114
Phone+1 617-726-1848

Fax+1 617-643-0697

Education & Training

Massachusetts General HospitalFellowship, Endocrinology, Diabetes, and Metabolism, 2003 - 2006
Massachusetts General HospitalResidency, Internal Medicine, 2001 - 2003
University of Texas Southwestern Medical SchoolClass of 2001
Trinity UniversityB.S., Biochemistry, 1990

Certifications & Licensure

MA State Medical License 2004 - 2025

Awards, Honors, & Recognition

Membership Alpha Omega Alpha, 2000
Membership Sigma Xi, 1997
President’s/Trustee Scholarship Trinity University, 1986

Clinical Trials

Continuous Glucose Monitoring With a Subcutaneous Sensor During Critical Illness and Surgery Start of enrollment: 2008 Jun 01
Completed
Not Applicable
Closed-loop Glucose Control for Automated Management of Type 1 Diabetes Start of enrollment: 2008 May 01
Completed
Not Applicable
Integration of Continuous Glucose Monitoring Into a BiHormonal Closed-Loop Artificial Pancreas Start of enrollment: 2010 Jul 01
Completed
Not Applicable
Pharmacokinetic Comparison of Intradermal Versus Sub-cutaneous Insulin and Glucagon Delivery in Type 1 Diabetes Start of enrollment: 2012 Aug 01
Unknown status
Phase 2
Outpatient Automated Blood Glucose Control With a Bi-hormonal Bionic Endocrine Pancreas Start of enrollment: 2013 Jan 01
Completed
Not Applicable
Inpatient Closed-loop Glucose Control Start of enrollment: 2013 Mar 01
Completed
Not Applicable
The Summer Camp Study: Blood Glucose Control With a Bi-Hormonal Bionic Endocrine Pancreas Start of enrollment: 2013 Apr 01
Completed
Not Applicable
Equivalence of A Stable Liquid Glucagon Formulation With Freshly Reconstituted Lyophilized Glucagon Start of enrollment: 2014 Apr 01
Completed
Phase 2, Phase 3
A Multicenter Study of Outpatient Automated Blood Glucose Control With a Bihormonal Bionic Pancreas Start of enrollment: 2014 Apr 01
Completed
Not Applicable
The Summer Camp Study 2: Blood Glucose Control With a Bi-Hormonal Endocrine Pancreas Start of enrollment: 2014 Jun 01
Completed
Not Applicable
Closed-Loop Glucagon Administration For Hypoglycemia Treatment Start of enrollment: 2014 Nov 01
Completed
Not Applicable
The iLet Introduction Study: A Feasibility Study of the iLet, a Fully Integrated Bihormonal Bionic Pancreas Start of enrollment: 2016 Mar 01
Terminated
Not Applicable
The Monitoring Study Start of enrollment: 2017 Apr 01
Completed
Not Applicable
Feasibility Trial Testing the Bionic Pancreas With ZP4207 Start of enrollment: 2016 Nov 01
Completed
Phase 2
Feasibility of Outpatient Closed Loop Control With the iLet Bionic Pancreas in Cystic Fibrosis Related Diabetes Start of enrollment: 2021 Aug 26
Completed
Not Applicable
Individualizing Automated Closed Loop Glucose Control Through Pharmacokinetic Profiling in an Insulin-Only Bionic Pancreas Start of enrollment: 2019 Mar 19
Terminated
Phase 2, Phase 3
The Set-Point Study for Type 2 Diabetes: Evaluating the Use of an Insulin Only Bionic Pancreas System in Type 2 Diabetes Start of enrollment: 2017 Jul 28
Completed
Not Applicable
The Bihormonal iLet Bionic Pancreas Feasibility Study Start of enrollment: 2019 May 15
Completed
Phase 2, Phase 3
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Publications & Presentations

PubMed

73 citations
Treatment-seeking behaviour in urban Sri Lanka: trusting the state, trusting private providers.
Steven Russell
Social Science & Medicine. 2005-10-01
94 citations
A Glycemia Risk Index (GRI) of Hypoglycemia and Hyperglycemia for Continuous Glucose Monitoring Validated by Clinician Ratings.
David C Klonoff, Jing Wang, David Rodbard, Michael A Kohn, Chengdong Li
Journal of Diabetes Science and Technology. 2023-09-01
59 citations
Addressing the structural drivers of HIV: a luxury or necessity for programmes?
Janet Seeley, Charlotte Watts, Susan Kippax, Steven Russell, Lori Heise
Journal of the International AIDS Society. 2012-06-14

Journal Articles

The Future of Care for Type 1 Diabetes
Nathan DM, Russell SJ, Canadian Medical Association Journal, 1/1/2013
Obtaining surrogate consent for a minimal-risk research study in the ICU setting
Larkin ME, Beauharnais CC,Magyar K, Macey L, Grennan K, Boykin E, Russell SJ, Clinical Trials, 1/1/2012
Role of microRNA Processing in Adipose Tissue in Stress Defense and Longevity
Mori MA, Raghavan P, Thomou T, Boucher J, Robida-Stubbs S, Macotela Y, Russell SJ, Kirkland JL, Blackwell TK, Kahn CR, Cell Metabolism, 1/1/2012
Impaired Thermogenesis and Adipose Development in Mice with Fat-Specific Disruption of Insulin and IGF-1 Signaling
Boucher J, Mori MA, Lee K, Liew CW, Macotela Y, Smyth G, Rourk M, Russell SJ, Bluher M, Kahn CR, Nature Communications, 1/1/2012
Efficacy Determinants of Subcutaneous Micro-Dose Glucagon during Closed-Loop Control
Russell SJ, El-Khatib FH, Nathan DM, Damiano ER, Journal of Diabetes Science and Technology, 1/1/2010
A Bi-Hormonal Closed-Loop Blood Glucose Control Device for Type 1 Diabetes
El-Khatib FH*, Russell SJ*#, Nathan DM, Sutherlin RG, Damiano ER (*Co-first authors; #, Corresponding author), Science Translational Medicine, 1/1/2010
Continuous Glucose Monitoring Awaits Its "Killer App”
Russell SJ, Journal of Diabetes Science and Technology, 1/1/2008
Mitochondrial Gene Expression and Increased Oxidative Metabolism: Role in Increased Lifespan of Fat-Specific Insulin Receptor Knockout Mice
Katic M, Kennedy AR, Leykin I, Norris A, McGettrick A, Gesta S, Russell SJ, Bluher M, Maratos-Flier E, Kahn CR, Aging Cell, 1/1/2007
Endocrine Regulation of Aging
Russell SJ, Kahn CR, Nature Reviews Molecular Cell Biology, 1/1/2007
Essential Role of Insulin and IGF-1 Receptor Signaling in Cardiac Development and Function
Laustsen PG, Russell SJ, Cui L, Entingh-Pearsall A, Holzenberger M, Liao R, Kahn CR, Molecular and Cellular Biology, 1/1/2007
The 19S Complex of the Proteasome Regulates Nucleotide Excision Repair in Yeast
Gillete TG, Huang W, Russell SJ, Reed SH, Johnston SA, Friedberg EC, Genes and Development, 1/1/2001
Selective Chemical Inactivation of AAA Proteins Reveals Distinct Functions of Proteasomal ATPases
Russell SJ, Gonzalez F, Joshua-Tor L, Johnston SA, Chemistry & Biology, 1/1/2001
Evidence that Proteolysis of Gal4 Can Not Explain the Transcriptional Effects of Proteasome ATPase Mutations
Russell SJ, Johnston SA, Journal of Biological Chemistry, 1/1/2001
The 19S Regulatory Complex of the Proteasome Functions Independently of Proteolysis in Nucleotide Excision Repair
Russell SJ, Reed SH, Huang W, Friedberg EC, Johnston SA, Molecular Cell, 1/1/1999
Sub-cellular Localization, Stoichiometry, and Protein Levels of 26S Proteasome Subunits in Yeast
Russell SJ, Steger KA, Johnston SA, Journal of Biological Chemistry, 1/1/1999
Isolation and Characterization of SUG2: A Novel ATPase Family Component of the Yeast 26S Proteasome
Russell SJ, Sathyanarayana UG, Johnston SA, Journal of Biological Chemistry, 1/1/1996
The Synthesis and X-ray Crystallographic Analysis of a Stable Norbornadienone: 17-oxo-7,16-methano-7,16-diphenylcyclopenta[d,e] tribenzo[a,h,j]antharacene
Plummer BF, Currey JA, Russell SJ, Steffen LK, Watson WH, Bourne SA, Structural Chemistry, 1/1/1995
Sterically Congested Polycyclic Aromatic Hydrocarbons with Nonoptimal Geometries 4,5-Didehydroacenapthene as a Precursor for the Synthesis of 7,14 Diphenyl-8,9-(1’,8’...
Plummer BF, Russell SJ, Reese WG, Watson WH, Krawiec M, Journal of Organic Chemistry, 1/1/1991
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Lectures

Triamcinolone Acetonide Extended-Release in Patients with Osteoarthritis and Type 2 Diabetes: A Randomized, Phase 2 Study
Boston, MA - 6/15/2014

Press Mentions

Results of the Insulin-Only Bionic Pancreas Pivotal Trial, Which Were Presented at ADA's 82nd Scientific Sessions, Are Published This Week in the New England Journal of MedicineSeptember 30th, 2022
Bionic Pancreas Bests Standard Care for Glycemic Control in T1DMSeptember 30th, 2022
The iLet® Bionic Pancreas Significantly Reduced HbA1c and Improved Time in Range vs Standard of Care for a Diverse Range of People with Type 1 DiabetesApril 30th, 2022
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