StevenBradleyHarrisMD

Internal Medicine • Ontario, CA

Geriatric Medicine

Director of Research at Critical Care Research, Inc. until retiring in 2021

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Office
415 Rosewood Ct
Ontario, CA 91764
Phone+1 909-376-6079

Summary

I have done aging research and practiced geriatrics, but for 20 years I found myself doing experimental resuscitation and cooling physiology in dogs. I retired from this in 2021.

I ran an institution where we did liquid lavage of the lungs in dogs, with fluorocarbons (which don't mix with water, but you cannot drown in them as they carry oxygen and CO2). Not only does this potentially wash out edema, blood, mucus, smoke, and drowning fluid (fresh or salt water), but (if you use warm or cold liquid) it can also cool and warm as fast as heart-lung bypass (1 C per minute for the brain). It can be used along with a normal gas ventilator.

We can induce mild hypothermia of the brain (-4 C or -7 F from normal) in anesthetized dogs in 5 minutes, and all it requires is intubation. Within a few hours they are up and walking, and they do fine. This is part of the future in medicine-- I think we will see it long before total liquid ventilation, where the lungs are entirely full of fluorocarbon. There is no reason for that but deep diving.

https://www.researchgate.net/profile/Steven_Harris12/contributions

Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Geriatric Medicine (Internal Medicine), 1986 - 1989
St Mary Medical CenterResidency, Internal Medicine, 1983 - 1985
University of Utah School of MedicineClass of 1983
Brigham Young UniversityB.S., Chemistry, 1979

Certifications & Licensure

CA State Medical License 1984 - 2024
UT State Medical License 1995 - 2014
American Board of Internal Medicine Internal Medicine

Publications & Presentations

Journal Articles

Comparison of high (5%) and low (1%) concentrations of micellar microemulsion propofol formulations with a standard (1%) lipid emulsion in horses
Boscan P, Steffey EP, Farver TB, Mama KR, Huang NJ, Harris SB, Am J Vet Res., 9/1/2006
The arrest of biological time as a bridge to engineered negligible senescence
Lemler J, Harris SB, Platt C, Huffman TM, Ann N Y Acad Sci., 6/1/2004
Rapid (0.5°C/min) minimally invasive induction of hypothermia using cold perfluorochemical lung lavage in dogs
Harris, S.B. Darwin, M.G., Russell, S.R., O’Farrell, Fletcher, Mike, and Wowk, Brian, Resuscitation, 8/1/2001
Vitrification enhancement by synthetic ice blocking agents
Wowk, B., Leitl, E., Rasch, C.M., Mesbah-Karimi, N., Harris, S.B., and Fahy, G.M., Cryobiology, 1/1/2000
Effects of Solute Methoxylation on Glass Forming Ability and Stability of Vitrification Solutions
Wowk, B., Darwin, M., Harris, S.B., Russell, S.R., and Rasch, C.M., Cryobiology, 1/1/1999
Serum glucose, glucose tolerance, corticosteroneand free fatty acids during aging in energy restricted mice
Harris, S.B.; Gunion, M.W.; Rosenthal, J.J.; and Walford, R.L., Mechanisms of Aging and Development, 1/1/1994
The calorically restricted low-fat nutrient-dense diet in Biosphere 2 significantly lowers blood glucose in humans
Walford, R.L.; Harris, S.B.; and Gunion, M.W., Proceedings of the National Academy of Sciences of the United States of America, 1/1/1992
Lack of effect of age and dietary restriction on DNA single-stranded breaks in brain, liver, and kidney of (C3H x C57BL/10) F1 mice
Fu, C.S.; Harris, S.B.; Wilhelmi, P.; and Walford, R.L., Journal of Gerontology, 1/1/1991
Dietary restriction alone and in combination with oral ethoxyquin/2-mercaptoethylamine in mice
Harris, S.B; Weindruch R.; Smith, G.S.; Mickey, M.R.; and Walford, R.L., Journal of Gerontology, 1/1/1990
Many are cold but few are frozen: a humanist looks at cryonics
Harris SB, Free Inquiry, Spring, 1/1/1989
Dietary restriction and aging: historical phases, mechanisms, current directions
Walford, R.L.; Harris, S.B.; and Weindruch R., J. Nutr., 1/1/1987
Phenotypic and genotypic characterization of monoclonal anti-digoxin antibodies
Pincus, S.H.; Watson, W.A.; Harris, S.B.; Ewing, L.P.; Stocks, C.J.; and Rollins, D.E., Life Sci., 1/1/1984
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Books/Book Chapters

Ribavirin: A Broad Spectrum Antiviral Agent.
Chapter: Ribavirin: structure and antiviral activity relationships.
Harris, S.B. and Robbins, R.K.Editors: Roberts A. Smith and William Kirkpatrick.Academic Press, San Francisco, CA1980

Other

A microemulsion preparation of high concentration propofol for anesthetic uses.
Harris, SB and Huang, N, Australia Pat. No. 2005215517
10/8/2009
Mixed-mode liquid ventilation gas and heat exchange.
Federowicz, M.G., Russell, S.R., and Harris, S.B., U.S. Patent 6, 694, 977
1/1/2004
Method for Vitrification of Biological Materials Using Alkoxylated Compounds.
Wowk, B., Federowicz, M.G., Russell, S.R., and Harris, S.B., U.S. Patent 5, 952, 168
1/1/1999

Authored Content

-1.2 ⁰C/MINUTE BRAIN COOLING BY FLUOROCARBON LUNG LAVAGE IN A DOG SURVIVAL MODELMarch 2018
The Immortality Myth and Technology7/1/1996
The Immortality Myth and TechnologyJuly 1996