StevenGunzlerMDFAAN

Movement Disorder

Associate Professor, Neurology, Case Western Reserve University School of Medicine and Senior Attending Physician, Parkinson's and Movement Disorders Center, University Hospitals Cleveland Medical Center

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Office
1611 S. Green Road
South Euclid, OH 44121
Phone+1 216-844-8685

Clinical Expertise

Multiple system atrophy, Huntington's disease, Progressive supranuclear palsy, Parkinson's disease, Lewy body dementia, Parkinson's disease and other movement disorders, Spasmodic torticollis, Corticobasal degeneration

Education & Training

Oregon Health & Science UniversityFellowship, 2004 - 2007
Icahn School of Medicine at Mount Sinai/Mount Sinai HospitalResidency, Neurology, 2001 - 2004
University of RochesterInternship, Internal Medicine, 2000 - 2001
University of Rochester School of Medicine and DentistryClass of 2000
Massachusetts Institute of TechnologyBS, Biology, Phi Beta Kappa, 1992 - 1996

Certifications & Licensure

OH State Medical License 2007 - 2027
OR State Medical License 2004 - 2007
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Fellow of the American Academy of Neurology (FAAN) AAN, 2023
The Edward L. Westbrook Teaching Excellence Award University Hospitals and Case Western Reserve University, 2017
Phi Beta Kappa MIT, 1996
Sigma Xi Scientific Honorary Society MIT, 1996
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Clinical Trials

Study to Evaluate the Safety and Efficacy of Davunetide for the Treatment of Progressive Supranuclear Palsy Start of enrollment: 2010 Oct 01
Completed
Phase 2, Phase 3
Study of Urate Elevation in Parkinson's Disease, Phase 3 Start of enrollment: 2016 Jun 01
Completed
Phase 3
A Study to Evaluate the Safety and Efficacy of IPX203 in Parkinson's Disease Participants With Motor Fluctuations Start of enrollment: 2018 Nov 06
Completed
Phase 3
Wearable Assessments in the Clinic and Home in PD Start of enrollment: 2019 Apr 24
Completed
Mitochondrial Biomarkers in Huntington's Disease Start of enrollment: 2019 Apr 04
Completed
Misfolded Proteins in the Skin of People With Parkinson's Disease and Other Parkinsonism Start of enrollment: 2019 Mar 12
Recruiting
Low Dose Apomorphine and Parkinsonism Start of enrollment: 2005 Oct 01
Withdrawn
Phase 2
Parkinson's Foundation PD GENEration Genetic Registry Start of enrollment: 2020 Dec 20
Recruiting
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Publications & Presentations

PubMed

BCKDK loss impairs mitochondrial Complex I activity and drives alpha-synuclein aggregation in models of Parkinson's disease.
Aya Jishi, Di Hu, Yutong Shang, Rihua Wang, Steven A Gunzler
Acta Neuropathologica Communications. 2024-12-21
A Call for Change: Updating the Operational Definition for Dementia in Parkinson's Disease.
Jaime Kulisevsky, Irene Litvan, Daniel Weintraub, Jennifer G Goldman, Alexander I Tröster
Movement Disorders Clinical Practice. 2024-12-17
Seeding activity of skin misfolded tau as a biomarker for tauopathies.
Zerui Wang, Ling Wu, Maria Gerasimenko, Tricia Gilliland, Zahid Syed Ali Shah
Molecular Neurodegeneration. 2024-11-29

Journal Articles

Neuropsychiatric aspects of Parkinson’s disease: Practical considerations
Higinbotham AS, Gunzler SA, Current Psychiatry, 10/2023
New neurological applications for botulinum toxin
Gunzler SA, Riley DE, UH Neurological Institute Journal, 2012

Books/Book Chapters

Encyclopedia of the Neurological Sciences
Chapter: Diseases of basal ganglia
Gunzler SA, Riley DEEditors: Aminoff MJ and Daroff RB.Elsevier, New YorkEdition 2nd,2014
Encyclopedia of the Neurological Sciences
Chapter: Dopamine
Gunzler SAEditors: Aminoff MJ and Daroff RB.Elsevier, New YorkEdition 2nd,2014
The Little Black Book of Neuropsychology
Chapter: Parkinson’s disease and other movement disorders
Page 567 - 646Gunzler S, Riley D, Maciunas R, Schoenberg MREditors: Schoenberg MR and Scott JG.Springer, New YorkEdition 1st,2011
Parkinson’s Disease: Diagnosis and Clinical Management
Chapter: Motor Fluctuations and Dyskinesia
Page 575 - 583Gunzler SA and Nutt JGEditors: Factor SA and Weiner WJ.Demos, New YorkEdition 2nd,2007
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Press Mentions

Could a Type of Dementia Be Diagnosed Through Skin? University Hospitals, Case Western Researchers Are Trying to Find OutJuly 29th, 2021
Study to See if Skin Biopsies Could Diagnose Lewy Body DementiaJuly 1st, 2021