StevenYChangMDPhD

PubMed

• 282 citations
  Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial.
  Wesley H. Self, Matthew W. Semler, Lindsay M. Leither, Jonathan D Casey, Derek C. Angus
  JAMA. 2020-12-01
• 17 citations
  Assessment of Symptom, Disability, and Financial Trajectories in Patients Hospitalized for COVID-19 at 6 Months.
  Andrew J Admon, Theodore J Iwashyna, Lee A Kamphuis, Stephanie J Gundel, Sarina K Sahetya
  JAMA Network Open. 2023-02-01
• 38 citations
  Obesity and smoking as risk factors for invasive mechanical ventilation in COVID-19: A retrospective, observational cohort study.
  Ana C. Monteiro, Rajat Suri, Iheanacho O Emeruwa, Robert Stretch, Roxana Y Cortes-Lopez
  Plos One. 2020-12-22

Journal Articles

• Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients with COVID-19  
  Matthew W Semler, Lindsay M Leither, Derek C Angus, Roy G Brower, Steven Y Chang, John C Eppensteiner, Michael R Filbin, Adit A Ginde, Michelle N Gong, Douglas L Hayde..., JAMA
• Protocols and hospital mortality in critically ill patients: The United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study (USCIITG-CIOS)  
  Sevransky, J.E., W. Checkley, P. Herrera, B.W. Pickering, J. Barr, S.M.Brown, S.Y. Chang, D. Chong, D. Kaufman, R.D. Fremont, T.D. Girard, J. Hoag, S.B. Johnson, M.P. ..., Critical Care Medicine, 1/24/2015
• Structure, process and annual ICU mortality across 69 centers: United Sates Critical Illness and Injury Trials Group Critical Illness Outcomes Study  
  Checkley, W., G.S. Martin, S. Brown, S.Y. Chang, O. Dabbagh, R.D. Fremont, T.D. Girard, M.D. Howell, S. Johnson, J. O’Brien, P.K. Park, S. Pastores, N.T. Patil, A.P. P..., Critical Care Medicine, 1/1/2014
• Contemporary Ventilator Management in Patients with and at risk of ALI/ARDS  
  Chang, S.Y., O. Dabbagh, O. Gajic, A. Patrawalla, M-C Elie, D. Talmor,A. Malhotra, A. Adesanya, H.L. Anderson III, J.M. Blum, P.K. Park, and M.N. Gong on behalf of the..., Respiratory Care, 1/1/2013
• Protocols in the management of critical illness  
  Chang, S.Y., J. Sevransky, G.S. Martin, Critical Care, 1/1/2012
• Early identification of patients at risk of acute lung injury: Evaluation of Lung Injury Prediction Score in a Multicenter Cohort Study  
  Gajic, O., O. Dabbagh, P.K. Park, A. Adesanya, S.Y. Chang, P. Hou, H. Anderson III, J.J. Hoth, M. Mikkelsen, N.T. Gentile, M.N. Gong, E. Bajwa, D. Talmor, on behalf of..., American Journal of Respiratory and Critical Care Medicine, 1/1/2011
• Regional ICU Care: The future is now  
  Chang, S.Y., S.L. Merwin, J.F. Fein, A.M. Fein, Journal of Intensive Care Medicine, 1/1/2010
• Critical Illness in the Obese Patient  
  Chang, S.Y., J.P. Kress, and J.B. Hall, Current Respiratory Medicine Reviews, 1/1/2008
• Critical Care Organization  
  Chang, S.Y., A.S. Multz, and J.B. Hall, Critical Care Clinics, 1/1/2005
• Mechanisms of CFTR regulation by Syntaxin 1A and PKA  
  Chang, S.Y., A. Di, A.P. Naren, H.C. Palfrey, K.L. Kirk and D.J. Nelson, Journal of Cell Science, 1/1/2002
• CFTR chloride channels are regulated by a SNAP 23/Syntaxin 1A complex  
  Cormet-Boyaka, E., A. Di, S.Y. Chang, A.P. Naren, A. Tousson, D.J. Nelson, and K.L. Kirk, Proceedings of the National Academy of Sciences, 1/1/2002
• Modal behavior of the mu1 Na+ channel and effects of coexpression of the beta1-subunit  
  Chang, S.Y., J. Satin, and H.A. Fozzard, Biophysical Journal, 1/1/1996
• Co-expression of beta1 cardiac Na channel alpha subunits in oocytes decreases lidocaine block  
  Makielski, J.C., J.T. Limberis, S.Y. Chang, Z. Fan, and J.W. Kyle, Molecular Pharmacology, 1/1/1996
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Books/Book Chapters

• Pulmonary Examination and Board Review 
  Chapter: HIV and the Lung 
  Arredondo, A, R. Huynh, and S.Y. ChangMcGraw-Hill, New York, NY2015
• Clinical Management of Pulmonary Arterial Hypertension 
  Chapter: Pulmonary Hypertension in the ICU 
  Chang, S.Y.Editors: J. Klinger, A. Talwar, A. Fein.Professional Communications Inc2015
• Manual of Critical Care 
  Chapter: The Systemic Inflammatory Response Syndrome and Septic Shock 
  Chang, S.Y., J. Edelson, and A.M. FeinEditors: S. Raoof.McGraw-Hill2009
• Just the Facts: Critical Care 
  Chapter: Echocardiography in the critically ill patient 
  Chang, S.Y.Editors: J.B. Hall & G.A. Schmidt.McGraw-Hill, New York, NY2007
• Irwin and Rippe’s Intensive Care Medicine 
  Chapter: Defining and measuring patient safety in the critical care unit 
  Fein, A.M., S.Y. Chang, D. Ost, J.E. Heffner, and S.L. MerwinEditors: R.S.S. Irwin & J.M. Rippe.Lippincott Williams & WilliamsEdition 6th,2007
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Abstracts/Posters

• Improving mechanical ventilator bundle compliance: A quality improvement project
  Albores, J., and S. Chang, American Journal of Respiratory and Critical Care Medicine, 1/1/2015
• Association between clinical protocols and hospital mortality in critically ill patients: United States Critical Illness and Injury Trials Group-Critical Illness Outco...
  Sevransky, J.E., W. Checkley, P.E. Morris, B.W. Pickering, J.B. Hoag, S. Shahul, M.P. Kerlin, M. Putman, N. Patil, J. Guzman, S.M. Brown, S. Pastores, R. Fremont, L. R..., American Journal of Respiratory and Critical Care Medicine, 1/1/2014
• Critical Illness Outcomes Study: An Observational Cohort of Critically Ill Patients
  Sevransky, J.E., W. Checkley, T.D. Girard, S.M. Pastores, S. Shahul, A. Martinez, S. Brown, N. Patil, T. O’Keffe, B. Pickering, J. Liebler, P. Park, J. , S. Chang, J. ..., American Journal of Respiratory and Critical Care Medicine, 1/1/2012
• Organizational structure of 27 intensive care units in the United States: 10 Critical Illness Outcomes Study (CIOS)
  Checkly, W., G.S. Martin, S. Brown, S.Y. Chang, O. Dabbagh, R. Fremont, T.D. Girard, M. Howell, S. Johnson, J. O’Brien, P.K. Park, S. Pastores, N. Patil, A. Pietropaol..., American Journal of Respiratory and Critical Care Medicine, 1/1/2011
• Early cumulative fluid balance and development of acute lung injury
  Park, P., N.O. Birkmeyer, N. Gentile, S.Y. Chang, O. Dabbagh., O. Gajic, American Journal of Respiratory and Critical Care Medicine, 1/1/2011
• Use of angiotensin converting enzyme inhibitors or angiotensin receptor blockers and clinical outcomes among patients at risk for Acute Lung Injury
  Watkins, T., L.B. Lemos-Filho, O. Dabbagh, S.Y. Chang, P.K. Park, M.N. Gong, American Journal of Respiratory and Critical Care Medicine, 1/1/2011
• Frequency and outcome of acute lung injury in hospitalized patients at risk: a multicenter cohort study
  Gajic, O., O. Dabbagh, P.K. Park, A. Adesanya, S.Y. Chang, P. Hou, H. Anderson III, J.J. Hoth, M. Mikkelsen, N.T. Gentile, M.N. Gong, E. Bajwa, D. Talmor, on behalf of..., American Journal of Respiratory and Critical Care Medicine, 1/1/2010
• Towards prevention of acute lung injury: identification of patients at risk at the time of hospital admission
  Gajic, O., O. Dabbagh, P.K. Park, A. Adesanya, S.Y. Chang, P. Hou, H. Anderson III, J.J. Hoth, M. Mikkelsen, N.T. Gentile, M.N. Gong, E. Bajwa, D. Talmor, on behalf of..., American Journal of Respiratory and Critical Care Medicine, 1/1/2010
• ALI/ARDS in Emergency Surgery: The U.S. Critical Illness and Injury Trials Group (USCIITG) Lung Injury Prevention Study Cohort
  Park, P., S. Chang, O. Gajic, O. Dabbagh, A Adesanya, J. Hoth, H. Anderson, on behalf of the U.S. Critical Illness and Injury Trials Group: Lung Injury Prevention Stud..., American Association for the Surgery in Trauma conference, 1/1/2010
• Interpretation of PFTs
  Chang, S.Y., Rutgers-NJMS – Medical Housestaff, 1/1/-1
• Pathophysiology of Sepsis
  Chang, S.Y., NYU School of Medicine – 2nd Year Medical Students, 1/1/2005
• Pulmonary Manifestations of Rheumatologic Disease
  Chang, S.Y., NYU School of Medicine – CME Course, 1/1/2005
• Management of ALI/ARDS
  Chang, S.Y., NYU School of Medicine – Medical Housestaff, 1/1/2005
• Etiology of prolonged mechanical ventilation in tertiary setting
  Quinones, A., R. Ali-Permell, R. Russo, S. Chang, E. Hussain, M. Nelson, A. Fein., Chest, 1/1/2003
• Regulation of ICFTR by Syntaxin 1A occurs predominantly via direct protein-protein interactions
  Di, A. S.Y. Chang, A.P. Naren, K.L. Kirk, and D. Nelson, Biophysical Journal, 1/1/2001
• Disruption of direct Syntaxin 1A-CFTR interaction results in increased channel activity in human airway epithelia
  Chang, S.Y., A. Di, A.P. Naren, K.L. Kirk, and D.J. Nelson, American Journal of Respiratory and Critical Care Medicine, 1/1/2001
• A putative interaction between HCLC-3 and CFTR
  Huang, P., A. Di, M.A. Kaetzel, K. Kirk, S. Chang, X.D. Johnson, and D.J. Nelson, Biophysical Journal, 1/1/2000
• CFTR cooperatively interacts with SNAP-23 and Syntaxin 1A
  Cormet-Boyaka, E., S. Chang, A. Di, A.P. Naren, D.J. Nelson, and K.L. Kirk, Pediatric Pulmonology, 1/1/2000
• Na channel beta1 association with cardiac Na channel alpha subunits demonstrated by lidocaine block
  Makielski, J.C., J.T. Limberis, S.Y. Chang, Z. Fan, and J.W. Kyle, Biophysical Journal, 1/1/1995
• Beta1-subunit expressed with adult rat skeletal muscle Na channel alpha-subunit restores a native-like fast gating mode
  Chang, S., J. Satin, J. Kyle and H. Fozzard, Biophysical Journal, 1/1/1995
• Rat brain beta1 Na channel subunit interacts with rat brain IIa, skeletal muscle (gamma1), and rat heart (RH1) alpha-subunits
  Kyle, J.W., S.Y. Chang, J. Satin, J.M. Fang, H.A. Fozzard, and R.B. Rogart, Biophysical Journal, 1/1/1993
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Lectures

• Pulmonary & Critical Care Core Lecture Series 
  1/1/2013
• The Acute Respiratory Distress Syndrome 
  Queens, NY - 1/1/2013
• Severe Sepsis and Septic Shock in 2007 
  1/1/2007
• Critical Care – Critical Care Core Lecture Series 
  1/1/2005
• Innovations in diagnosis and treatment of pulmonary embolism 
  San Diego, CA - 1/1/2005
• Right ventricular dysfunction in critical illness 
  Orlando, FL - 1/1/2004
• Critical Care Lectures Series for Fellows 
  1/1/-2
• Housestaff Lectures Series – Topics in Critical Care 
  1/1/-3
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