StephenD.SilbersteinMD

Neurology • Philadelphia, PA

Headache

Professor of Neurology; and Director, Jefferson Headache Center, at Thomas Jefferson University

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Office
900 Walnut St
Philadelphia, PA 19107
Phone+1 215-955-2243

Fax+1 215-955-2060

Education & Training

University of Pennsylvania Health SystemResidency, Neurology, 1972 - 1975
University of Pennsylvania Health SystemResidency, Internal Medicine, 1967 - 1969
Perelman School of Medicine at the University of PennsylvaniaClass of 1967

Certifications & Licensure

PA State Medical License 1968 - 2024
MD State Medical License 1971 - 2023
NJ State Medical License 1974 - 2019
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Philadelphia Magazine Castle Connolly, 2004-2014
America's Top Doctors Castle Connolly, 2004-2014
Women's Health Castle Connolly, 2008
Men's Health Castle Connolly, 2007
Super Doctor SuperDoctors.com
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Clinical Trials

An Open Label Study Using Consecutive Intravenous Depacon With Oral Depakote ER for the Treatment of Cluster Headaches. Start of enrollment: 2003 Jul 01
Completed
Not Applicable
Clinical Study Examining Use of an Over-the-Counter Supplement for the Prevention of Menstrually-Associated Migraine Headache Start of enrollment: 2003 May 01
Completed
Not Applicable
A Study Examining the Use of a Migraine Medicine in the Treatment of Two Migraine Attacks in Patients Who Have Increased Skin Sensitivity Start of enrollment: 2003 Dec 01
Completed
Not Applicable
A Research Study to Examine the Difference Between Local Anesthetics Alone and Local Anesthetics Plus Steroids in the Treatment of Chronic Headache Start of enrollment: 2005 Jun 01
Completed
Not Applicable
A Research Study Examining the Use of Olanzapine for the Prevention of Migraine Start of enrollment: 2004 May 01
Terminated
Not Applicable
Study of Lornoxicam or Placebo for Acute Treatment of the Headache of Migraine. Start of enrollment: 2005 Dec 01
Completed
Phase 2
PREMIUM Migraine Trial Start of enrollment: 2006 Jan 01
Completed
Not Applicable
A Research Study To Evaluate If Frovatriptan Is Safe And Effective In Preventing Migraine Headache After Fasting Start of enrollment: 2007 Jul 01
Completed
Not Applicable
NINDS CRC Chronic Migraine Treatment Trial Start of enrollment: 2008 Oct 01
Completed
Phase 3
Do Patients With Chronic Daily Headache Have Continuous Headache or Moments of Headache Relief? Start of enrollment: 2009 Apr 01
Completed
Pilot Study to Collect and Evaluate Data on the Use of IV* Ibuprofen in the Treatment of an Acute Migraine Attack Start of enrollment: 2011 Jun 01
Completed
Phase 4
STOPAIN in the Treatment of a Single Migraine Attack Start of enrollment: 2012 May 01
Completed
Not Applicable
Incobotulinum Toxin for the Treatment of Trigeminal Neuralgia Start of enrollment: 2014 Mar 14
Terminated
Phase 2
A Study of Galcanezumab (LY2951742) in Participants With Migraine Headache Start of enrollment: 2014 Jul 07
Completed
Phase 2
A Study of Galcanezumab in Participants With Chronic Cluster Headache Start of enrollment: 2015 Jun 18
Completed
Phase 3
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Publications & Presentations

PubMed

Clinical factors associated with day-to-day peak pain severity in individuals with chronic migraine: A cohort study using daily prospective diary data.
Marina Vives-Mestres, Amparo Casanova, Stephen D Silberstein, Andrew D Hershey, Serena L Orr
Headache. 2024-09-01
Insights from 25 years of onabotulinumtoxinA in migraine - mechanisms and management.
Patricia Pozo-Rosich, Alicia Alpuente, Stephen D Silberstein, Rami Burstein
Nature Reviews. Neurology. 2024-09-01
Sustained benefits of onabotulinumtoxinA treatment in chronic migraine: An analysis of the pooled Phase 3 REsearch Evaluating Migraine Prophylaxis Therapy (PREEMPT) ra...
Stephen D Silberstein, Hans-Christoph Diener, David W Dodick, Katherine Sommer, Richard B Lipton
Headache. 2024-06-22

Journal Articles

Health Care Resource Utilization and Migraine Disability Along the Migraine Continuum Among Patients Treated for Migraine
Stephen Silberstein, MD, Headache: The Journal of Head and Face Pain

Press Mentions

What Will Be the Next Big Breakthrough in Migraine Research?May 13th, 2022
Ctrl M HealthJune 24th, 2021
Pulmatrix Reports First Quarter 2021 Financial Results and Provides Business UpdateMay 11th, 2021
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