Stephen C. Pflugfelder MD

Ophthalmology•Houston, TX

Cataract Related

Professor of Ophthalmology, Baylor College of Medicine

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6550 Fannin StSuite 1501Houston, TX 77030
Phone+1 713-798-6100
Fax+1 713-798-4231

Education & Training

Baylor College of Medicine/Cullen Eye InstituteResidency, Ophthalmology, 1982 - 1985
Presbyterian Medical Center of the University of Pennsylvania Health SystemInternship, Transitional Year, 1981 - 1982
SUNY Upstate Medical UniversityClass of 1981

Certifications & Licensure

NY State Medical License 1986 - Present
TX State Medical License 2001 - 2026
FL State Medical License 1985 - 2016
PA State Medical License 1981 - 1988
American Board of Ophthalmology Ophthalmology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2007-2014
Top Doctors:SE Texas Castle Connolly, 2013
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Super Doctor SuperDoctors.com
Top MD Consumers Checkbook
Fellow (FAAO) American Academy of Ophthalmology
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Clinical Trials

Efficacy and Safety Study of Nutritional Supplements for Treatments of Dry Eye Start of enrollment: 2008 Sep 01
Completed
Not Applicable
Effects of Dry Eye Treatments on the Ocular Surface Start of enrollment: 2013 Feb 01
Completed
Phase 4
The Effects of Cyclosporin A in a Low Humidity Environment, on the Ocular Surface Start of enrollment: 2014 Mar 01
Terminated
Not Applicable
Evaluation of Efficacy of 20 µg/ml rhNGF New Formulation (With Anti-oxidant) in Patients With Stage 2 and 3 NK Start of enrollment: 2015 Feb 01
Completed
Phase 2
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Publications & Presentations

PubMed

Destructive and protective effects and therapeutic targets of IL-36 family cytokines in dry eye disease.
Xin Chen, Na Lin, Haixia Liu, Jing Lin, Ning Gao
The Ocular Surface. 2025-04-01
2 citations
Changes in conjunctival mononuclear phagocytes and suppressive activity of regulatory macrophages in desiccation induced dry eye.
Jehan Alam, Ebru Yaman, Cintia S de Paiva, De-Quan Li, Gerda Cristal Villalba Silva
The Ocular Surface. 2024-10-01
Mouse Corneal Immune Cell Heterogeneity Revealed by Single-Cell RNA Sequencing.
Ebru Yaman, Nicole Heyer, Cintia S de Paiva, Mary Ann Stepp, Stephen C Pflugfelder
Investigative Ophthalmology & Visual Science. 2024-10-01

Journal Articles

Accessibility to and Quality of Human Eye Tissue for Research: A Cross-Sectional Survey of ARVO Members
Andrew M Williams, Stephen Pflugfelder, Investigative Ophthalmology and Visual Science

Press Mentions

Clinical Challenges: The Role of Inflammation in Dry Eye DiseaseMay 23rd, 2023
Vision Research in the SpotlightFebruary 16th, 2022
The Detection, Causes, Consequences, and Management of Tear InstabilityMay 4th, 2019
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Grant Support

Effects of cornea epithelial barrier disruption on the cornea trigeminal neural circuitBAYLOR COLLEGE OF MEDICINE2022–2027
Effects of cornea epithelial barrier disruption on the cornea trigeminal neural circuitBAYLOR COLLEGE OF MEDICINE2022–2027
Multi-method investigation and characterization of the ocular microbiomeBAYLOR COLLEGE OF MEDICINE2023–2026
Multi-method investigation and characterization of the ocular microbiomeBAYLOR COLLEGE OF MEDICINE2023–2026
Multi-method investigation and characterization of the ocular microbiomeBAYLOR COLLEGE OF MEDICINE2023–2026
Pathogenesis of Conjunctival Squamous MetaplasiaBAYLOR COLLEGE OF MEDICINE1997–2025
Pathogenesis of Conjunctival Squamous MetaplasiaBAYLOR COLLEGE OF MEDICINE1997–2025
Pathogenesis of Conjunctival Squamous MetaplasiaBAYLOR COLLEGE OF MEDICINE1997–2025
Environmentally-Induced Ocular Surface Inflammation Mimicking Sjogren'S SyndromeNational Eye Institute2009–2010
EBV And Ocular Pathology In Sjogren'S SyndromeNational Eye Institute1990–1992
Detection Of Epstein-Barr Viral DNA In Ocular SpecimensNational Eye Institute1989

Professional Memberships

American Academy of Ophthalmology - AAO
Fellow