StephenLittleMDFRCPC, FACC, FASE

PubMed

• Impact of systolic dominant pulmonary venous flow morphology on outcomes after mitral transcatheter edge-to-edge repair.
  Sahar Samimi, Taha Hatab, Rody Bou Chaaya, Chloe Kharsa, Fatima Qamar
  Catheterization and Cardiovascular Interventions. 2024-11-01
• Outcomes of mitral transcatheter edge-to-edge repair in patients with mitral annular calcification: A meta-analysis.
  Sahar Samimi, Taha Hatab, Chloe Kharsa, Rody G Bou Chaaya, Fatima Qamar
  Cardiovascular Revascularization Medicine. 2024-10-30
• 1 citations
  Meta-Analysis of Dedicated vs Off-Label Transcatheter Devices for Native Aortic Regurgitation.
  Sahar Samimi, Taha Hatab, Chloe Kharsa, Safi U Khan, Rody G Bou Chaaya
  JACC. Cardiovascular Interventions. 2024-10-25

Journal Articles

• Emerging Trends in Heart Valve Engineering: Part III Novel Technologies for Mitral Valve Repair and Replacement  
  Kheradvar A, Groves EM, Simmons CA, Griffith BE, Alavi SH, Tranquillo RT, Dasi LP, Falahatpisheh A, Grande-Allen KJ, Goergen CJ, Mofrad MRK, Baaijens FPT, Canic S, Lit..., Ann Biomed Eng, 1/7/2014
• Functional 3D Printed Patient-Specific Modeling of Severe Aortic Valve Stenosis  
  Maragiannis D, Jackson M, Igo S, Chang SM, Zoghbi WA, Little SH, J Am Coll Cardiol, 1/1/2014
• Museum of TMH multimodality imaging center: cardiac amyloidosis  
  Le D, Zaid R, Cruz JD, Nabi F, Little S, Methodist Debakey Cardiovasc J, 1/1/2014
• Development of a Multi-Modality Compatible Flow Loop System for the Functional Assessment of Mitral Valve Prostheses  
  Jackson MS, Igo SR, Lindsey TE, Maragiannis D, Chin KE, Autry K, Shah DJ, Valsecchi P, Kline WB, Little SH, Cardiovascular Engineering and Technology, 1/1/2014
• Prognostic Value of Delayed Enhancement Cardiac Magnetic Resonance Imaging in Mitral Valve Repair  
  Chaikriangkrai K, Lopez-Mattei JC, Lawrie G, Ibrahim H, Quinones MA, Zoghbi W, Little SH, Shah DJ, Ann Thorac Surg, 1/1/2014
• Pre-and Post-Operative Diastolic Dysfunction in Patients with Valvular Heart Disease: Diagnosis and Therapeutic Implications  
  Zaid R, Barker C, Little S, Nagueh S, JACC, 1/19/2013
• Antiplatelet and anticoagulation for patients with prosthetic heart valves  
  Massel DR, Little SH, Cochrane Database Syst Rev, 1/1/2013
• Antiplatelet and anticoagulation for patients with prosthetic heart valves (Meta-Analysis)  
  Little SH, Massel D, Cochrane Database Syst Rev, 1/1/2013
• Museum of TMH Multimodality Imaging Center: Pseudoaneurysm of the Ascending Aorta  
  Polsani V, Little SH, Methodist DeBakey Cardiovascular Journal, 1/1/2013
• Quantification of Chronic Functional Mitral Regugitation by Automated 3-D Peak and Integrated Proximal Isovelocity Surface Area and Stroke Volume Techniques Using Real...  
  Thavendiranathan P, Liu S, Datta S, Rajagopalan S, Ryan T, Igo S, Jackson MS, Little SH, De Michelis N, Vannan M, Circ Cardiovasc Imaging, 1/1/2013
• Museum of TMH Multimodality Imaging Center: Left Ventricular Pseudoaneurysm  
  Lopez-Mattei J, Nabi F, Little SH, Shah D, Methodist DeBakey Cardiovascular Journal, 1/1/2013
• Vanishing Constriction  
  Dela Cruz JD, Shah D, Little SH, Methodist DeBakey Cardiovascular Journal, 1/1/2013
• Superior Vena Cava Syndrome Associated with Metastatic Adenocarcinoma to the Heart: The Diagnostic Utility of Cardiac Resonance Imaging  
  Kassi M, Polsani V, Takei H, Estep J, Shah D, Little S, Methodist DeBakey Cardiovascular Journal, 1/1/2013
• Assessment of Prosthetic Valve Function and Para-Valvular Regurgitation after Transcatheter Aortic Valve Replacement  
  Polsani V, Little SH, Curr Opin Cardiol, 1/1/2013
• 3D Vena Contracta Area to Quantify Severity of Mitral Regurgitation: A Practical New Tool?  
  Maragiannis D, Little S, Hellenic J of Cardiol, 1/1/2013
• Early Post-Operative Dysfunction of a Mechanical Aortic Valve  
  Shah T, Ramlawi B, Buergler J, Chang SM, Little SH, Methodist DeBakey Cardiovascular Journal, 1/1/2012
• Is it Really Getting Easier to Assess Mitral Regurgitation using the Proximal Isovelocity Surface Area?  
  Little SH, Journal of the American Society of Echocardiography, 1/1/2012
• The Vena Contracta Area: Conquering Quantification with a 3-Dimensional Cut?  
  Little SH, JACC Cardiovascular Imaging, 1/1/2012
• Validation of a 3D Computational Fluid-Structure Interaction Model Simulating Flow through an Elastic Aperture  
  Quaini A, Canic S, Glowinski R, Igo S, Hartley CJ, Zoghbi W, Little S, Journal of Biomechanics, 1/1/2012
• Direct Assessment of Normal St Jude Mechanical Mitral Valve Orifice Area by Real-Time 3 Dimensional Echocardiography  
  Krim SR, Vivo RP, Patel A, Xu J, Igo SR, Zoghbi WA, Little SH, Am Coll Cardiol Img, 1/1/2012
• Multimodality Noninvasive Imaging for Transcatheter Aortic Valve Implantation: A Primer  
  Little SH, Shah DJ, Mahmarian JJ, Methodist DeBakey Cardiovascular Journal, 1/1/2012
• Direct assessment of normal mechanical mitral valve orifice area by real-time 3D echocardiography  
  Krim SR, Vivo RP, Patel A, Xu J, Igo SR, Zoghbi WA, Little SH, JACC Cardiovasc Imaging, 1/1/2012
• Three-dimensional echocardiography to quantify mitral valve regurgitation  
  Little S, Curr Opin Cardiol, 1/1/2012
• 3D Echocardiography to Quantify Mitral Regurgitation  
  Little SH, Current Opinion in Cardiology, 1/1/2012
• Comparative evaluation of Mitral Valve Strain by deformation tracking in 3D-Echocardiography  
  Ben Zekry S, Lawrie G, Little S, Zoghbi W, Freeman J, Jajoo A, Jain S, He J, Martynenko A, Azencott R, Cardiovascular Engineering and Technology, 1/1/2012
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Books/Book Chapters

• Cardiothoracic Surgery in the Elderly 
  Chapter: Cardiac Imaging in the Elderly 
  Page 157 - 192Little SH, Chang SM, Nabi F, Shah DJEditors: Katlic MR.Springer, New York, NYEdition 1st,2011
• MICCAI 2007-10th International Conference, Brisbane, Australia. Oct. 29-Nov.02, 2007. LNCS 4792, Part II 
  Chapter: Towards Subject-Specific Models of the Dynamic Heart for Image-Guided Mitral Valve Surgery. 
  Page 94 - 101Linte CA, Wierzbicki M, Moore J, Guiraudon GM, Little SH, Peters TMEditors: N. Ayache, S. Ourselin, A. Maeder.Springer, Verlag Berlin Heidelberg2007
• Proceedings of International Workshop on Optimal Control in Image Processing, Heidelberg, Germany, May 31-June 2, 2010 
  Chapter: Optimal Control in Image Processing. 
  Azencott R, Glowinski R, He J, Hoppe RHW, Jajoo A, Li Y, Martynenko A, Ben Zekry S, Little SH, Zoghbi WASpringer, Berlin-Heidelberg-New York

Abstracts/Posters

• [Board 066] Impact of Moderate/Severe Mitral Regurgitation on 2-Year Outcomes After Transcatheter Aortic Valve Replacement in the Reprise Iii Randomized Controlled Trial
  Stephen Little, 2019 ACC Scientific Session & Expo, New Orleans, New Orleans, 3/17/2019
• Cardiac MRI Functional Assessment of Bioprosthetic Mitral Valves: An In-Vitro Comparison Against Doppler Echocardiography.
  Maragiannis D, Jackson MS, Chin K, Igo S, Autry K, Zoghbi WA, Shah DJ, Little SH, Society for Cardiovascular Magnetic Resonance Scientific Sessions, Nice, France, 1/1/2015
• Bioprosthetic Mitral Valve Effective Orifice Area Using 4D Flow Cardiac Magnetic Resonance Derived Time Velocity Integral. An In-Vitro Comparison with Doppler Echocard...
  Maragiannis D, Jackson MS, Igo SR, Chin K, Autry K, Ghosn M, Shah DJ, Little SH, Society for Cardiovascular Magnetic Resonance Scientific Sessions, Nice, France, 1/1/2015
• Impact of Late Gadolinium Enhancement with Cardiac Magnetic Resonance on Mortality in Moderate to Severe Aortic Stenosis.
  Adigun R, Chaikriangkrai K, Ghosn M, Little SH, Zoghbi WA, Nabi F, Shah DJ, American Heart Association Scientific Sessions, Chicago, IL, 1/1/2014
• Prognostic Value of Preoperative Myocardial Fibrosis Assessment by Delayed Enhancement Cardiac Magnetic Resonance Imaging in Patients Undergoing Mitral Valve Repair.
  Chaikriangkrai K, Lopez-Mattei JC, Ibrahim H, Little SH, Zoghbi W, Quinones MA, Lawrie G, Shah DJ, SCMR 2014 Scientific Sessions, New Orleans, LA, 1/1/2014
• Expanding the Characterization of Mitral Valve Disease Using Models Created in a Flow Loop Bioreactor.
  Connell PS, Azimuddin A, Kim E, Jackson M, Little SH, Grande-Allen KJ, American College of Cardiology Scientific Sessions, Washington, DC, 1/1/2014
• Association of Coronary Artery Calcium Score and Left Ventricular Diastolic function in Patients with Normal Stress Study and Preserved Ejection Fraction.
  Maragiannis D, Chaikriangkrai K, McGregor K, Chin K, Little SH, Nagueh SF, Chang SM, American Society of Echocardiography Annual Scientific Sessions, Portland, OR, 1/1/2014
• Quantification of Multiple Mitral Regurgitant Jets: An In vitro Assessment of Doppler methods pertaining to MitraClip.
  Maragiannis D, Jackson MS, Igo SR, Zoghbi WA, Little SH, American Heart Association Scientific Sessions, Chicago, IL, 1/1/2014
• Replacement and Interstitial Fibrosis by Cardiac MR and Diastolic dysfunction in HCM.
  Maragiannis D, Ghosn MG, Green P, Shah DJ, Little SH, Nagueh SF, American Society of Echocardiography Annual Scientific Sessions, Portland, OR, 1/1/2014
• Functional Evaluation of 3D Printed Patient Specific Models of Severe Aortic Valve Stenosis.
  Maragiannis D, Jackson M, Igo S, Schutt R, Little SH, American Society of Echocardiography Annual Scientific Sessions, Portland, OR, 1/1/2014
• Cardiac Magnetic Resonance 4D Flow: An In Vitro Validation of Bioprosthetic Mitral Valve Flow Volume Quantification.
  Ghosn M, Chaikriangkrai K, Shah DJ, Little SH, American Heart Association Scientific Sessions, Dallas, TX, 1/1/2013
• Prediction of Optimal Deployment Angle for TAVR-Feasibility of CT Angiography and Non-Contrast DynaCT Image Registration Based Approach and Its Potential Implication o...
  Barker CM, Chinnadurai P, Ramlawi B, Chintalapani G, Chang SM, Al-Marzooq M, Lin CH, Veasey J, Nabi F, Little S, Mahmarian J, Reardon M, Kleiman N, American College of Cardiology Annual Scientific Sessions, San Francisco, CA, 1/1/2013
• Development of a Multi-Modality Imaging Model of Dynamic Mitral Valve Dysfunction.
  Jackson M, Igo S, Maragiannis D, Chin K, Shah D, Little S, JACC; American College of Cardiology Annual Scientific Sessions, San Francisco, CA, 1/1/2013
• Development of a Multi-Modality MRI Compatible Circulatory Flow system for the Functional Assessment of Mitral Valve Prostheses.
  Jackson M, Igo S, Maragiannis D, Chin K, Karmonik C, Zoghbi W, Shah D, Little S, JASE; American Society of Echocardiography 24st Annual Scientific Sessions, Minneapolis, MN, June 28-July 3, 2013, 1/1/2013
• Multi-Modality Imaging of Type-B Aortic Dissection Using a Novel Hemodynamic Model.
  Patel A, Igo S, Maragiannis D, Jackson M, Shah D, Lumsden A, Little S, Bismuth J, BSME 2013 Annual Meeting, Seatle, WA, 1/1/2013
• Cardiac Magnetic Resonance Imaging for the Functional Assessment of Normal Bioprosthetic Mitral Valves: A Comparison Against In Vitro Flow Transducer and Doppler Echoc...
  Maragiannis D, Jackson MS, Igo SR, Chin K, Autry K, Ghosn M, Shah D, Little SH, American Heart Association Session, Dallas, TX, 1/1/2013
• Doppler Evaluation of Functional Patient Specific 3D Printed Models of Severe Aortic Valve Stenosis.
  Jackson M, Igo S, Maragiannis D, Little S, BSME 2013 Annual Meeting, Seatle, WA, 1/1/2013
• Doppler Evaluation of a Functional Patient Specific 3D Printed Model of Severe Aortic Valve Stenosis.
  Maragiannis D, Jackson MS, Igo SR, Reardon M, Little SH, JASE; American Society of Echocardiography 24st Annual Scientific Sessions, Minneapolis, MN, June 28-July 3, 2013, 1/1/2013
• Development of an in vitro circulatory flow loop system for multi-modality flow assessment of mitral valve dysfunction and repair.
  Jackson M, Igo S, Shah D, Reardon M, Little SH, Southern Biomedical Engineering Conference, Houston, TX, 1/1/2012
• Accurate Quantification of Chronic Mitral Regugitation by Automated True 3-D Proximal Isovelocity Surface Area Using Real-Time Volume Color Flow Doppler Transthoracic ...
  Thavendiranathan P, Liu S, Datta S, Ryan T, Igo S, Jackson MS, De Michelis N, Little SH, Vannan M, ACC.12 61st Annual Scientific Session & Expo, Chicago, IL, 1/1/2012
• Development of an MRI-compatible in vitro mock circulation system for functional assessment of mitral valve prosthesis.
  Jackson M, Igo S. Shah D, Reardon M, Little SH, Southern Biomedical Engineering Conference, Houston, TX, 1/1/2012
• Regurgitation Quantification using 3D PISA in Volume Echocardiography.
  Grady L, Datta S, Kutter O, Duong C, Wein W, Igo SR, Little SH, Liu S, Vannan M, 14th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), Toronto, Ontario, 1/18/2011
• Comparison of real-time 3-dimensional PISA measurement and 2-dimensional PISA calculation in the assessment of aortic regurgitation.
  Pirat B, Little SH, Chang SM, Tiller L, Kumar R, Zoghbi WA, EUROECHO & Other Imaging Modalities, 1/1/2011
• Quantitative Dynamic Curvature Changes of the Normal Mitral Valve Leaflets during Systole: Insights from Novel Mitral Valve Modeling.
  Ben Zekry S, Alexander SK, Jain S, Li Y, Aggarwal A, Azencott R, Lawrie GM, Little SH, Zoghbi WA, American Society of Echocardiography 21st Annual Scientific Sessions, 1/12/2010
• Novel Parameters of Global and Regional Mitral Annulus Geometry: Comparison among Normals, Organic Mitral Regurgitation and Following Mitral Valve Repair.
  Ben Zekry S, Jain S, Alexander SK, Li Y, Aggarwal A, Jajoo A, Little SH, Lawrie GM, Azencott R, Zoghbi WA, American Society of Echocardiography 21st Annual Scientific Sessions, 1/12/2010
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Lectures

• Choosing the Appropriate Patient for Edge-to-Edge Repair 
  CRF Transcatheter Cardiovascular Therapeutics - Annual Symposium 2019 - Miami, FL - 9/26/2019
• Imaging in Structural Heart Disease: How Can 3D Printing Help With Perioperative Planning ? 
  2019 ACC Scientific Session & Expo, New Orleans - 3/17/2019
• Cardiac CT for Diagnosing and Guiding Treatment in Structural Heart Diseases 
  2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
• 3D Printing: Nice to Have or Necessity? 
  2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
• Moving Blood, Removing Boundaries: A story of Collaboration. 
  Houston, TX - 1/23/2015
• Combined Mitral and Aortic Valve Dysfunction. 
  Washington, DC - 1/31/2014
• Ideal Transcatheter Heart Valve Position. 
  Washington, DC - 1/31/2014
• Paravalvular Regurgitation. 
  Washington, DC - 1/29/2014
• Co-Chair-Imaging for Valvular Heart Disease. 
  Washington, DC - 1/29/2014
• Predicting THV Paravalvular Regurgitation. 
  Washington, DC - 1/28/2014
• 3D Echo: Defining Valve Morphometry. 
  Portland, OR - 1/20/2014
• Co-Chair: Imaging and Clinical Decision Making in Complex Valve Disease. 
  Chicago, IL - 1/16/2014
• Echocardiography for TAVR: The Landing Zone. 
  Washington, DC - 1/15/2014
• 3D Prosthetic Valve Functional Imaging. 
  Atlanta, GA - 1/14/2014
• In Vitro 3D Valve Modeling. 
  Houston, TX - 1/14/2014
• Moderator: 3D echo case studies. 
  Atlanta, GA - 1/14/2014
• Prosthetic Valve Update 2014. 
  Amarillo, TX - 1/13/2014
• Is 3D Echo the New Standard for Quantitating Regurgitation? 
  Dallas, TX - 1/12/2014
• Interventional Imaging: A New Niche. 
  Austin, TX - 1/11/2014
• Prosthetic Valve Echo Guidelines. 
  Austin, TX - 1/11/2014
• MV Case-Demonstrating MV Pathoanatomy. 
  Austin, TX - 1/11/2014
• Endocarditis: Diagnosis and Complications. 
  Austin, TX - 1/11/2014
• Moderator-Complex Cases-Saves and Regrets. 
  Austin, TX - 1/11/2014
• Moderator-Functional Valve Imaging. 
  Austin, TX - 1/11/2014
• Evaluation of the Aortic Valve: A Debate-3D TEE: The New Standard? 
  Dallas, TX - 1/10/2014
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Other

• "Prosthetic Heart Valves: What to Measure, What Test, and How Frequently." (Interviewed by: Glenn A. Hirsch, MD) 
  Little, SH, An International Audio Journal of Cardiovascular Surgery and Medicine-American College of Cardiology
  1/1/2013
• "Endocarditis." 
  Little SH, Ramlawi B, American College of Cardiology Self Assesment Program (ACCSAP; 8th Edition)
  1/1/2012