StephenEmersonMDPhD

PubMed

• 96 citations
  Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.
  Yi Zhang, Ashley R. Sandy, Jina Wang, Vedran Radojcic, Gloria T. Shan
  Blood. 2009-11-20
• 51 citations
  Clinical and immunologic impact of CCR5 blockade in graft-versus-host disease prophylaxis
  Ryan H. Moy, Austin P. Huffman, Lee P. Richman, Lisa Crisalli, Ximi K. Wang
  Blood. 2017-02-16
• 83 citations
  Nf-ya activates multiple hematopoietic stem cell (hsc) regulatory genes and promotes hsc self-renewal
  Stephen G. Emerson, Jiang Zhu, Alevtina Domashenko
  Proceedings of the National Academy of Sciences of the United States of America. 2007-02-08

Journal Articles

• Long-term functional engraftment of mesenchymal progenitor cells in a mouse model of accelerated aging  
  Singh, L., Brennan, T.A., Kim J.-H., Egan, K.P., McMillan, E.A., Chen, Q., Hankenson, K.D., Zhang, Y., Emerson, S.G., Johnson, F.B., Pignolo, R.J., Stem Cells, 1/1/2013
• NF-Y is a Key Regulator of Hematopoietic Stem Cell (HSC) regulatory genes and isEssential for Cycling but not Quiescent HSCs  
  Bungartz , B., Land H., Scadden, D.T., Emerson, S.G., Blood, 1/1/2012
• Prevention of Graft-versus-Host Disease by Blocking Lymphocyte Chemotaxis  
  Reshef, R., Luger, S.M., Hexner, E.O., Loren, A.W., Frey, N.V., Nasta, S.D., Goldstein, S.C. Stadtmauer, E.A. Smith, J., Bailey, S., Mick, R., Heitjan, D.F., Emerson, ..., NEJM, 1/1/2012
• NF-Ya Protein Delivery As a Tool for Hematopoietic Progenitor Cell Expansion  
  Domashenko, A., Wiener, S., Emerson, S.G., Methods in Molecular Biology, 1/1/2012
• Notch signaling is a critical regulator of allogeneic T cell responses mediating graft-versus-host disease  
  Zhang, Y. Sandy, A.R, Wang, J., Kato, K., He, S., Tran, I., Shan, G.T., Friedman, A., Hexner, E., Emerson, S.G., Pear, W.S., Maillard, I., Blood, 1/1/2011
• A tribute to Alan M Gewirtz  
  Turka, L.A. and Emerson, S.G., J Clin Invest, 1/1/2011
• CD8+ Effector T Cells Proliferate and Persist Upon Chronic Exposure to Alloantigensthrough Reactivation of Stem Cell Transcriptional Programs  
  Kato, K., Cui, S., Kuick, R., Mineishi, S., Hexner, E., Ferrara, J.L.M., Marquez, V.E., Emerson, S.G.,and Zhang, Y., Biol Blood Marr Transpl, 1/1/2010
• TAT-mediated transduction of NF-Ya peptide induces the ex vivo proliferation and engraftment potential of human hematopoietic progenitor cells  
  Domashenko, A.D., Danet-Desnoyers, G., Aron, A., Carroll,M.P., Emerson, S.G., Blood, 1/1/2010
• Immune Reconstitution: How it Should Work, What's Broken, and Why it Matters Hematopoietic Transplantation Education Program  
  Gress, R.E., Emerson, S.G., Drobyski, W.R., Biology of Blood and Marrow Transplantation, 1/1/2010
• Dual Requirement for Gsk3 in Hematopoietic Stem Cell Maintenance  
  Huang, J., Zhang, Y, Bersenev, A., O'Brien, S.T., Tong, W., Emerson, S.G., Klein P.S., J Clin Invest, 1/1/2009
• Bone and Blood Vessels: The Hard and the Soft of Hematopoietic Stem Cell Niches  
  Garrett, R., and Emerson, S.G., Cell Stem Cell, 1/1/2009
• Lestaurtinib (CEP701)is a JAK2 inhibitor that suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative di...  
  Hexner EO, Serdikoff C, Jan M, Swider CR, Robinson C, Yang S, Angeles T, Emerson SG, Carroll M, Ruggeri B, Dobrzanski P, Blood, 1/1/2008
• PTH, IGFs and the Osteoblast Niche: Physiology and Pharmacologic Potential  
  Garrett, R. and Emerson, S.G., Endocrinology, 1/1/2008
• Stem Cell Biology and Memory Stem Cells  
  Emerson, S.G., Proceedings of the American Clinical and Climatological Association, 1/1/2008
• At Least Two Populations of Stem Cells are Necessary to Form an Ectopic Skeleton  
  Kaplan, F.S., Glaser, D.L., Shore, E.M., Pignolo, R.J., Zhang, Y., Senitzer, D., Forman, S.J., Emerson, S.G., Journal of Bone and Joint Surgery, 1/1/2007
• Osteoblasts support B lymphocyte commitment and differentiation  
  Zhu,J., Garrett, R., Jung, Y., Zhang, Y., Kim, N., Wang, J., Joe, G.J., Hexner, E., Choi, Y., Taichman R., Emerson, S.G., Blood, 1/1/2007
• 4 c-Myb Contributes to G2/M Cell Cycle Transition in Human Hematopoietic Cells by Direct Regulation of Cyclin B1 Expression  
  Nagata, Y., Shetzline, S., Sakashita, C., Kalota, A., Rallapalli, R., Rudnick, S.J., Zhang, Y., Emerson, S.G., Gewirtz, Mol Cell Biol, 1/1/2007
• Annexin II expressed by osteoblasts and endothelial cells establishes the hematopoietic stem cell niche  
  Jung, Y., Wang, J., Song, J., Wang, J., Havens, A., Sun Y., Emerson, S.G., Kresbsbach, P.H., Taichman, R.S., Blood, 1/1/2007
• Thrombopoietin, Hematopoietic Stem Cells and the Osteoblst Niche: Holding on Loosely, but not Letting Go  
  Emerson, S.G., Cell Stem Cell, 1/1/2007
• Enhanced Graft-Vs-Tumor Activity Of Donor Leukocyte Infusions Expanded Ex-Vivo By Activation With CD3/CD28 Co-Stimulation  
  Porter, D.L., Levine, B., Bunin, N., Stadtmauer, E., Luger, S., Goldstein, S., Schuster, S., Tsai, D., Nasta, S., Loren, A., Perl, A., Emerson, S.G., Sohal, A., Veloso..., Blood, 1/1/2006
• Location, Location, Location: c-kit- Stem Cells in the Adult Liver  
  Emerson, S.G., The Hematologist, 1/1/2006
• Hematologists and the Stem Cell Revolution  
  Emerson, S.G., The Hematologist, 1/1/2006
• Two Nickels are Worth a Dime, and Sometimes More: Proteasome Inhibitors for GVHD  
  Emerson, S.G., 1/1/2006
• Keratinocyte Growth Factor as a Thymic Stimulant in Stem Cell Transplantation  
  Emerson, S.G., The Hematologist, 1/1/2006
• When the Gold (Standard) Does Not Glisten  
  Emerson, S.G., The Hematologist, 1/1/2006
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Books/Book Chapters

• "The Vanishing Physician Scientist" 
  Chapter: Engaging Undergraduate Students in Research: Sustaining our Nation's Pipeline of Future Biomedical Investigators. 
  Emerson, S.G., Punt, J.A., Meneely, P.Editors: Andrew Schafer, MD.Cornell University Press2009
• Hematopoietic Stem Cell Transplantation 
  Chapter: Stem Cell Biology. 
  Page 3 - 18Hexner, E., and Emerson, S.G.Editors: R. Soiffer.Springer2008
• Hematopoiesis 
  Chapter: The Role Of Osteoblasts in Hematopoietic Stem Cell Biology. 
  Page 476 - 486Emerson, S.G., Taichman, R.S., Adams, S.Editors: Leonard Zon.Oxford University Press2001
• Kelley'sTextbook of Internal Medicine 
  Chapter: Approach to the Patient with Leukocytosis. 
  Page 1598 - 1601Emerson, S.G.Editors: D.H.Humes.Lippincott, Inc.Edition 4th,2000
• Stem Cells in Tissue Biology 
  Chapter: The Role of Osteoblasts in Hematopoiesis. 
  Page 421 - 432Taichman, R.S. Emerson, S.G.Editors: Greenberger J.S..1999
• Advances in Allogeneic Hematopoieitc Stem Cell Transplantation 
  Chapter: Clinical Application of Hematopoietic Stem Cell Culture and Expansion. 
  Page 377 - 388Emerson, S.G., Conrad, P.Editors: Burt, R.K., and Brush, M.M..Kluwer Academic Publishers1999
• Hematologic Pathophysiology 
  Chapter: Hematopoiesis: The Development of Blood Cells. 
  Page 1 - 24Emerson, S.G.Editors: F. Schiffman.Lippincott, Inc.1998
• Cytokines and Biological Response Modifiers: A Transfusion Medicine Primer 
  Chapter: Cytokines in Ex-Vivo Stimulation of Blood Progenitor Cells. 
  Page 195 - 214Emerson, S.G.Editors: R.D. Davenport and E.L. Snyder.AABB, Inc.1997
• Textbook of Internal Medicine 
  Chapter: Approach to the Patient with Leukocytosis. 
  Page 318 - 321Emerson, S.G.Editors: W.N. Kelley.Lippincott, Inc.Edition 2nd,1996
• Technical and Biological Components of Marrow Transplantation 
  Chapter: In Vitro Expansion of Hematopoietic Cells for Clinical Application. 
  Page 215 - 223Emerson, S.G., Palsson, B.O., Clarke, M.F., Silver, S.M., Adams, P.T., Koller, M.R., Van Zant, G., Rummel, S., Armstrong, R.D., Maluta, J., Douville, J., Paul, L.1995
• Clinical Laboratory Medicine 
  Chapter: Hematopoietic Growth Factors. 
  Page 817 - 826Farnen, J.F., Emerson, S.G.Editors: K.McClatchey.William and Wilkins1994
• The Bone Marrow Microenvironment 
  Chapter: The Role of Cytoadhesion in Human Stem Cell Differentiation. 
  Page 283 - 298Caldwell J., Palsson, B.O., and Emerson, S.G.Editors: M. Long, M. Wicha.John Hopkins University Press1993
• High Dose Cancer Chemotherapy 
  Chapter: The Hematopoietic Microenvironment. 
  Page 143 - 150Emerson, S.G.Editors: J. Armitage, K. Antman.Williams and WilkensEdition 1st,1992
• Proceedings of the 5th International Symposium of Autologous Bone Marrow Transplantation 
  Chapter: Integration of molecular biology and genetics with biological and chemotherapeutic approaches to the rearrangement of chronic myelogenous leukemia (CML). 
  Page 229 - 236Deisseroth A, Wedrychowski A, Seong D, Sims S, Paslidis N, Romine M, Howard OMz, Claxton D, Kornblau S, Herst CV, Yuan T, Fu M, Hu M, Johnson E, Gao P-Q, Huston L, Eme...Editors: Dicke K, Armitage JO, and Dick-Evinger MJ.1991
• New Strategies in Bone Marrow Transplantation 
  Chapter: Novel Approaches to the Therapy of CML. 
  Page 163 - 169Deisseroth, A.B., Herst, C.V., Wedrychowski, A., Sims, S., Seong, D., Johnson, E., Yuan, T., Romine M, Paslidis, N., Emerson, S., Feinberg, A., Gao, P., Huston, L., Cl...Editors: Champlin, R., and Gale, R.P..Wiley-Liss, Inc.1991
• Hematology: Basic Principles and Practice 
  Chapter: The Stem Cell Model of Bone Marrow Differentiation. 
  Page 72 - 81Emerson, S.G.Editors: E.J. Benz, H.J. Cohen, B. Furie, R.Hoffman, S.Shattil.Churchill Livingstone, Inc.1991
• Chronic Myelogenous Leukemia 
  Chapter: Cell Mediated Hematopoietic Regulation in CML. 
  Page 337 - 348Guba, S.C., Emerson, S.G.Editors: A.B. Deisseroth.Marcell Dekker1990
• Radiation Damage to Bone Marrow 
  Chapter: Hematopoiesis Following Bone marrow Transplantation. 
  Page 339 - 350Emerson, S.G., Gale, R.P.Editors: N Testa, R.P. Gale.Elsevier, No. Holland Publication1987
• Humoral and Cellular Regulation of Erythropoiesis 
  Chapter: ErythroidHelper Cell Dysfunction Following Bone Marrow Trans-plantation. 
  Page 135 - 148Emerson, S.G.Editors: ES Zanjani, M Tavassoli.Spectrum Publications1987
• The Lymphocyte: Structure and Function 
  Chapter: Cell Surface Dynamics. 
  Page 57 - 70Cone, R.E., Emerson, S.G.Editors: J.J. Marchalonis.Marcell DekkerEdition 2nd,1978
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Lectures

• “Stem Cells and the Immune System.” 
  University of Michigan, Ann Arbor, MI - 9/15/2013
• “The Future of Cancer Centers as Organizers of Health Care Delivery.” 
  Roswell Park Memorial Institute, Buffalo, NY - 6/14/2013
• Commencement Address. 
  Shipley School, Bryn Mawr, PA - 6/6/2011
• “Basic Discovery and Translational Research.” 
  Irvine, CA - 7/24/2010
• “Osteoblasts and Hematopoiesis.” 
  Glasgow, Scotland - 6/22/2010
• “La Remise d’une letter de Descartes au Pere Marin Mersenne." 
  L'Institut de France, Paris, France - 3/8/2010
• “Preparation for College and University Education in the 21st Century.” 
  Westtown School, Westtown, PA - 1/15/2010
• "Individuals, Leadership and History" 
  Haverford, PA - 6/5/2009
• "Academic Careers for Physician Scientists." 
  National Institutes of Health, Bethesda, MD - 5/20/2009
• "Learning and Discovery in Friends Education." 
  Merion, PA - 9/4/2008
• "From Dendritic Exosomes to Memory Stem Cells." 
  Yale University, Westbrook, CT - 1/11/2008
• "The Stem Cell Revolution in Biology and Medicine." 
  Tucson, AZ - 10/3/2007
• “Stem Cell and the Immune Response.” 
  Northwestern University School of Medicine, Chicago, IL - 5/25/2007
• “NF-Y and Stem Cell Renewal.” 
  Yale University, New Haven, CT - 1/25/2007
• “Cellular Determinants of GVHD" 
  Dana Farber Cancer Institute, Harvard Medical School, Boston, MA - 10/12/2006
• Ocala Royal Dames Visiting Prize Lectureship 
  University of Florida, Gainsville, FL - 9/30/2006
• Bai-Yu-Lan Prize Lecture 
  Fudan University, Shanghai, China - 8/30/2006
• “The Cellular Cascade of GVHD" 
  Jiao-Tong University, Shanghai, China - 8/29/2006
• “Stem Cells and Memory T Cell Subsets" 
  Memorial Sloan Kettering Cancer Institute, New York, NY - 5/18/2006
• “Memory Stem Cells and Chronic Immune Responses" 
  Paris, France - 3/25/2006
• “Host APCs, Memory Stem Cells and CD4 Help in the Induction and Evolution of GVHD" 
  M.D. Anderson Cancer Institute, Houston, TX - 1/31/2006
• “Osteoblasts, B Cells, and Stem Cells,” 
  Ann Arbor, MI - 1/12/2006
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Other

• Reponse. In, “Remise d’une letter de Descartes au Pere Marin Mersenne (1641) a la Bibliotheque de l’Institut de France par Haverford College. 
  Emerson, S.G., Palais de L’institut
  1/1/2010
• Radiolabeling of p-Bz-DOTA-CD-11c antibody with 88Y: Conjugation, Labeling, Biodistribution studies. 
  Brockmann, J., Maus, S., Senekowitsch-Schmidtke, R., Wester, H.J, Emerson, S.G., Rosch, F., Kemchemie Univ. Mainz.
  1/1/2000
• The turnover and shedding of cell membrane proteins by murine spleen cells in culture. (Doctoral Dissertation) 
  Emerson, S.G., Yale University
  1/1/1980
• "Methods and Compositions for the Optimization of Human Hematopoietic Progenitor Cell Cultures." 
  Stephen G. Emerson, Michael F. Clarke, Bernhard O. Palsson, Richard M. Schwartz, U.S. Patent: No. 5,399,493
• "Method for the Ex Vivo Replication of Stem Cells, for the Optimization of Hematopoietic Progenitor Cell Cultures, and for Increasing the Metabolism, GM-CSF Secretion ... 
  Stephen G. Emerson, Michael F. Clarke, Bernhard O. Palsson, U.S. Patent: No. 5,437,994
• “Methods for Regulating the Specific Lineages of Cells Produced in a Human Hematopoietic Cell Culture." 
  Bernhard O. Palsson, R. Douglas Armstrong, Michael F. Clarke, Stephen G. Emerson, U.S. Patent: No. 5,635,386
• “Methods and Compositions for the Ex Vivo Replication of Human Hematopoietic Stem Cells." 
  Bernhard O. Palsson, R. Douglas Armstrong, Michael F. Clarke, Stephen G. Emerson, U.S. Patent: No. 5,670,351
• “Compositions Containing Cultured Mitotic Human Stem Cells" 
  Bernhard O. Palsson, R. Douglas Armstrong, Michael F. Clarke, Stephen G. Emerson, U.S. Patent: No. 5,670,147
• “Methods, Compositions and Devices for Maintaining and Growing Human Stem and/or Hematopoietic Cells." 
  Bernhard O. Palsson, Stephen G. Emerson, Richard M. Schwartz, U.S. Patent: No. 8,290,773
• “Methods, compositions and devices for maintaing and growing human stem and/or hematopoietic cells.” 
  Palsson, Bernhard O., Stephen G. Emerson, Richard M. Schwartz, U.S. Patent: No. 5,763,266
• “Hematopoietic Cells: Compositions & Methods Concerning Stem Cell Co-Culture with Osteoblasts." 
  Russell S. Taichman, Stephen G. Emerson, U.S. Patent: No. 5,733,541
• “Devices for maintaining and growing human stem and/or hematopoietic cells." 
  Bernhard O. Palsson, Stephen G. Emerson, Richard M., Schwartz, U.S. Patent: No. 5,888,807
• "Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism,... 
  Stephen G. Emerson, Michael F. Clarke, Bernhard O. Palsson, U.S. Patent: No. 6,326,198
• “Methods For Regulating The Specific Lineages Of Cells Produced In A Human Hematopoietic Cell Culture, Methods For Assaying The Effect Of Substances On Lineage-Specifi... 
  Bernhard O., Palsson, R. Douglas Armstrong, Michael F. Clarke, Stephen G. Emerson, U.S. Patent: No. 6,667,034
• "Inhibition of Immune Function by Targeting Antigen Presenting Cells." 
  Warren Shlomchik, Mark Shlomchik, Stephen G. Emerson, U.S. Patent: No. 7,288,255
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