StephanAriyanMD

Hand, Head & Neck, Plastic & Reconstructive Microsurgery

Frank F. Kanthak Professor Emeritus of Surgery ( Plastic Surgery, Surgical Oncology, Otolaryngology ) and of Dermatology. Former Associate Chief, Department of Surgery. Former Chief, Division of Plastic Surgery. Founding Director, Melanoma Program. Yale University, School of Medicine

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Office
333 Cedar Street
3rd Floor
New Haven, CT 06510
Phone+1 203-785-2571

Fax+1 203-785-5714

Summary

Dr. Ariyan is an internationally known surgeon specializing in the treatment of patients with head and neck cancer, breast cancer, and malignant melanoma. He has been recognized for the origination and development of several myocutaneous flaps for reconstructions of the head and neck- most notably the pectoralis major flap, which has become the most commonly used flap for head and neck reconstruction worldwide. He established the Microsurgery Service at Yale in 1976, performing the first replantations of fingers in Connecticut. He developed and performed the first composite microvascular reconstruction of the jaw using the anterior vascular supply to the rib and overlying soft tissues. He established the Yale Melanoma Unit in 1976, and continues to this day as the Director of that multispecialty team.

Following the devastating earthquake in Armenia in December 1988, he was invited by the government of the then Soviet Union to help care for the many victims. After assessing the situation, he recommended the training and establishment of a western standard plastic surgical unit to care for the reconstruction of the vast number of patients. He was asked to select a team of surgeons, anesthesiologists, and nurses from Armenia, which he trained at Yale from 1990-1991, with the joint collaborative efforts of the AGBU, the USAID, the ECFMG, the RRC for Plastic Surgery, the Yale School of Medicine, and the Yale-New Haven Hospital. That team has been successfully working together at the new Plastic and Reconstructive Surgery Center in Yerevan since its opening in 1992. The success of this effort has been used by the USAID as the model for the implementation of health care education in the redevelopment of the former Soviet Eastern European countries.

Education & Training

University of New HavenM.B.A., 1992 - 1993
University of New HavenMBA, 1991 - 1993
Yale UniversityM.A. (Honorary), 1981
UICC Fellowship at Sydney University Hospital, AustraliaFellowship, Melanoma Investigations, 1980 - 1980
Yale-New Haven Medical CenterFellowship, Hand Surgery (Plastic Surgery), 1976 - 1976
Yale-New Haven Medical CenterResidency, Plastic Surgery - Integrated, 1975 - 1976
Yale-New Haven Medical CenterResidency, Surgery, 1974 - 1975
Yale-New Haven Medical CenterResidency, Plastic Surgery - Integrated, 1973 - 1974
Yale-New Haven Medical CenterResidency, Surgery, 1971 - 1973
Yale-New Haven HospitalFellowship, NIH Cancer Felowship, 1970 - 1971
University of California (San Diego) Medical CenterResidency, Surgery, 1967 - 1968
Los Angeles County-Harbor-UCLA Medical CenterInternship, Transitional Year, 1966 - 1967
New York Medical CollegeClass of 1966
Long Island UniversityB.S., 1959 - 1962

Certifications & Licensure

NY State Medical License 1967 - Present
CA State Medical License 1968 - 2025
CT State Medical License 1969 - 2025
American Board of Plastic Surgery Plastic Surgery
American Board of Plastic Surgery Plastic Surgery within the Head and Neck

Awards, Honors, & Recognition

Albert Nelson Marquis Lifetime Achievement Award Marquis Who's Who, 2017
Medal of Honor New York Medical College, 2016
Robert Goldwyn Lifetime Achievement Award New Englans Society of Plastic Surgeons, 2015
Distinguished Fellow American Association of Plastic Surgeons, 2010
Presidential Citation American Head & Neck Society, 2002
Presidential Award Republic of Armenia, 1994
Distinguished Service Award Society of Head & Neck Surgeons, 1989
Robert Goldwyn Lifetime Achievement Award New England Society of Plastic and Reconstructive Surgeons, 2015
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2014
Clinical Excellence Award Yale Cancer Center, 2013
Top Doctors US News & World Report, 2012-2014
Presidential Citation American Head and Neck Society, 2002
Top Doctors of New York Metro Area Castle Connolly, 2001, 2012
Best Doctors of New York New York Magazine, 2001
How To Find the Best Doctors Castle Connolly, 1999
First Prize, Essay Educational Foundation American Society of Plastic & Reconstructive Surgeons, 1996, 1998
National Visiting Professor Society of Head and Neck Surgeons, 1995
Presidential Award Republic of Armenia, CIS, 1994
Presidential Award American Society for Head and Neck Surgery, 1993
Best Doctors in America Woodward/White, 1993, 1997, 2008, 2013
Kabakjian Award, Outstanding Contribution in a Field of Science 1991
Outstanding Medical Specialists in the US Town & Country Magazine, 1989
Distinguished Service Award Society of Head and Neck Surgeons, 1989
Best Breast Cancer Doctors Good Housekeeping Magazine, 1989
Distinguished Teacher Award Yale Plastic Surgery, 1983, 1988, 1993, 2000, 2005, 2007, 2009, 2011
Third Prize, Clinical Research Educational Foundation American Society of Plastic & Reconstructive Surgeons, 1979
First Prize, Basic Science Research Educational Foundation American Society of Plastic & Reconstructive Surgeons, 1979
First Prize, Resident Papers New York Regional Society of Plastic & Reconstructive Surgery, 1976
First Prize in Head and Neck Surgery, Plastic Surgery Chief Resident's Conference Educational Foundation of the American Society of Plastic & Reconstructive Surgeons, 1976
Honorable Mention, Resident Papers American Association for Hand Surgery, 1976
Honorable Mention, Resident Papers, Connecticut Chapter American College of Surgeons, 1975
First Prize in Basic Research, Plastic Surgery Chief Resident's Conference Educational Foundation of the American Society of Plastic & Reconstructive Surgeons, 1974
Sigma Xi Yale University, 1973
Scholar American College of Surgeons, 1973
NY State Partial Scholarship New York Medical College, 1962
Phi Sigma Long Island University, 1961
Alpha Epsilon Delta Long Island University, 1961
Trustees' Full Scholarship Long Island University, 1959
Fellow (FACS) American College of Surgeons
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Publications & Presentations

PubMed

283 citations
Exome sequencing identifies recurrent mutations in NF1 and RASopathy genes in sun-exposed melanomas
Michael Krauthammer, Yong Kong, Antonella Bacchiocchi, Perry Evans, Natapol Pornputtapong
Nature Genetics. 2015-09-01
3 citations
Skeletal muscle for cardiac assist.
George V. Letsou, John H. Braxton, John A. Elefteriades, Stephan Ariyan
Cardiology Clinics. 1995-02-01
2 citations
Skeletal Muscle Ventricles in Continuity with the Bloodstream
Ozuru O. Ukoha, John H. Braxton, George V. Letsou, James F. Hogan, Stephen Ariyan
Journal of Cardiac Surgery. 1996-07-01

Journal Articles

Comparison of the expression of vimentin and actin in spitz nevi and spitzoid melanomas
Alomari AK, Klump V, Neumeister V, Ariyan S, Narayan D, Lazova R, Am J Dermatopath, 1/1/2015
Using topical imiquimod for the management of positive insitu margins after melanoma resection
Pandit AS, Geiger E, Ariyan S, Narayan D, Choi J, Cancer Med, 1/1/2015
Eruptive melanocytic nevi heralding the diagnosis of metastatic melanoma: a case report
Kibbi N, Ariyan S, Slogoff F, Lazova R, Choi JN, JAAD Case Reports, 1/1/2015
Exome sequencingestablishes the role of NF1 in sun-exposed melanoma and provides insights into melanoma driver genes and impact on drug response
Krauthammer M, Kong Y, Evans P, Bacchiocchi A, Pomputtapong N, Wu C, McClusker JP, Ma S, Cheng E, Straub R, Serin M, Bosenberg M, Ariyan S, Narayan D, Sznol M, Kluger ..., Nature Genetics, 1/1/2015
Antibiotic prophylaxis for preventing surgical site infection in Plastic Surery: An evidence based Consensus Conference statement from the American Association of Plas...
Ariyan S, Martin J, Lal A, Cheng D, Borah G, Chung K, Conly J, Havlik R, Lee WPA, McGrath MH, Pribaz J, Young VL, Plast Reconstr Surg, 1/1/2015
Scalp melanoma and intransit metastases: a retrospective case-controlled study
Teng E. Sue GR, Sawh-Martinez R, Nishikawa S, Ariyan S, Natarajan A, Narayan D, Am Surg, 1/1/2014
Management of head and neck melanoma: Results of a national survey
Sawh-Martinez R, Douglas , Pavri S, Ariyan S, Narayan D, Ann Plast Surg, 1/1/2014
Clinical characteristics associated with Spitz Nevi and Spitzoid Malignant Melanomas: the Yale University Spitzoid Neoplasm Repository Experience, 1991 to 2008
Lott JP, Wititsuwannakul J, Lee JT, Ariyan S, Narayan D, Kluger H, Lazova R, J Amer Acad Dermatol, 1/1/2014
Desmoplastic melanoma: a 12-year experience with sentinel lymph node biopsy
Broer N, Walker M, Goldberg C, Buonocore S, Braddock D, Lazova R, Narayan D, Ariyan S, Eur J Surg Oncol, 1/1/2013
Use of the external pectoralis myocutaneous major flap in anterior skull base reconstruction
Kadlub N, Shin JH, Ross DA, Della Torre T, Ansari E, Persing JA, Ariyan S, Int J Oral Maxillofac Surg, 1/1/2013
A targeted approach to sentinel lymph node biopsyies in the parotid region for ead and neck melanomas
Samra S, Sawh-Martinez R, Tom L, Colebunders B, Salameh B, Truini C, Ariyan S, Narayan D, Ann Plast Surg, 1/1/2012
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
Krauthammer M., Kong Y, Ha P, Evans P, Bacchiocchi A, McCusker JP, Cheng E, Davis MJ, Goh G, Choi M, Ariyan S, Narayan D, Dutton-Regester K, Capatana A, Holman EC, Bo..., Nature Genetics, 1/1/2012
Integrated analysis of tumor samples sheds light on tumor heterogeneity
Parisi F, Micsinai M, Strino F, Ariyan S, Narayan D, Bacchiocchi A, Cheng E, Xu F, Li P, Kluger H, Halaban R, Kluger Y, Yale J Biol Med, 1/1/2012
A variant in a MicroRNA complementary site in the 3’ UTR of the KIT oncogene increases risk of acral melanoma
Godshalk SE, Paranjape T, Nallur S, Speed W, Chan E, Molinaro AM, Bacchiocchi A, Hoyt K, Tworkoski K, Stem DF, Sznol M, Arian S, Lazova R, Halaban R, Kidd KK, Weidhaas..., Oncogene, 1/1/2011
Letter to the Editor: Excising value at a marginal cost: Rethinking the management of basal cell carcinoma
Patel A, Clune JE, Mody P, Price G, Ariyan S, Plast Reconstr Surg, 1/1/2011
Letter to the Editor: A prospective trial on the use of antibiotics in hand surgery
Patel A, Forte AJ, Ariyan S, Plast Reconstr Surg, 1/1/2011
Metachrenous primary melanoma and lymphoma
McIntosh BC, Ariyan S, Esche G, Zelterman D, Narayan D, Ann Plast Surg, 1/1/2010
PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF(WT) melanoma cells
Halaban, R, Zhang W, Bacchiocchi A, Cheng E, Parisi F, Ariyan S, Krauthammer M, Mccusker J P, Kluger Y, Sznol M, Pigment Cell Melanoma Res, 1/1/2010
Cadaveric allograft for wound closure after resection of squamous cell carcinoma in patients with recessive dystrophic epidermolysis bullosa
Buonocore, SD, Ariyan S, Ann Plast Surg, 1/1/2009
Sentinel lymph node biopsies in melanoma How many nodes do we need?
Abou-Nukta F, Ariyan S, Ann Plast Surg, 1/1/2008
A randomized study comparing the effectiveness of methylene blue dye with Lymphazurin blue dye in sentinel node biopsy for the treatment of cutaneous melanoma
Liu Y, Truini C, Ariyan S, Ann Surg Onc, 1/1/2008
Toxicity and activity of a twice daily high-dose Bolus Interleukin-2 regimen in patients with metastatic melanoma and metastatic renal cell cancer
Acquavella N, Kluger H, Rhee J, Farber L, Tara H, Ariyan S, Narayan D, Kelly W, Sznol M, J Immunother, 1/1/2008
Arterial coupling for microvascular free tissue transfer
Chernichenko N, Ross DA, Shin J, Chow JY, Sasaki CT, Ariyan S, Laryngoscope, 1/1/2008
Diagnosis and treatment of interval sentinel lymph nodes in patients with cutaneous melanoma
Carling T, Pan D, Ariyan S, Narayan D, Plast Reconstr Surg, 1/1/2007
Tissue-specific expression of Rab33A and gene suppression by promoter methylation in early melanocytic lesions
Cheng E, Trombetta S, Kovacs D, Beech RD, Ariyan S, Reyes M, McNiff J, Narayan D, Kluger H, Halaban R, J Invest Derm, 1/1/2006
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Books/Book Chapters

Current Reconstructive Surgery.
Chapter: Head and Neck Cancer.
Ariyan SEditors: JM Serletti and JE Losee.McGraw-Hill, Ne2009
Plastic Surgery
Chapter: Salivary Gland Tumors.
Ariyan S, Narayan D, Ariyan CEEditors: S. Mathes.WB Saunders, Philadelphia, PAEdition 2nd,2006
Plastic Surgery
Chapter: Radiation Injuries.
Ariyan SEditors: S. Mathes.WB Saunders, Philadelphia, PAEdition 2nd,2006
Plastic Surgery
Chapter: Principles of Cancer Management.
Ariyan SEditors: S. Mathes.WB Saunders, Philadelphia, PAEdition 2nd,2006
Plastic Surgery
Chapter: Management of Metastatic Disease of the Head and Neck.
Ariyan SEditors: S. Mathes.WB Saunders, Philadelphia, PAEdition 2nd,2006
Plastic Surgery
Chapter: Cutaneous Melanoma.
Ariyan SEditors: S. Mathes.WB Saunders, Philadelphia, PAEdition 2nd,2006
Melanoma
Ariyan SClinics in Plastic Surgery, W.B. Saunders, Philadelphia, PA2000
The Hand Book (Reprinted)
Ariyan SR E Publishing, New Haven, CT1999
Plastic Surgical Reconstruction: Possibilities In Surgical Oncology II.
Ariyan SSurgical Oncology Clinics of North America, C. V. Mosby, St. Louis, MO1997
Grabb's Encyclopedia of Flaps.
Chapter: Sternocleidomastoid muscle and musculocutaneous flaps for pharyngoesophageal reconstruction.
Ariyan SEditors: B. Strauch, L.O. Vasconez, E. Hall-Findlay.Lippincott-Raven, HagerstownEdition 2nd,1997
Grabb's Encyclopedia of Flaps.
Chapter: Sternocleidomastoid muscle and musculocutaneous flaps for intraoral reconstruction.
Ariyan SEditors: B. Strauch, L.O. Vasconez, E. Hall-Findlay.Lippincott-Raven, HagerstownEdition 2nd,1997
Grabb's Encyclopedia of Flaps.
Chapter: Pectoralis major muscle and musculocutaneous flaps for chest wall reconstruction.
Ariyan SEditors: B. Strauch, L.O. Vasconez, E. Hall-Findlay.Lippincott-Raven, HagerstownEdition 2nd,1997
Grabb's Encyclopedia of Flaps.
Chapter: Pectoralis major muscle and musculocutaneous flaps for cheek and neck reconstruction.
Ariyan SEditors: B. Strauch, L.O. Vasconez, E. Hall-Findlay.Lippincott-Raven, HagerstownEdition 2nd,1997
Plastic Surgical Reconstruction: Possibilities In Surgical Oncology I.
Ariyan SSurgical Oncology Clinics of North America, C. V. Mosby, St. Louis, MO1996
An Atlas of Microsurgical Composite Tissue Transplantation.
Chapter: The Anterior Approach for Microvascular Transfer of Ribs
Ariyan SEditors: D. Serafin.WB Saunders, Philadelphia, PA1996
My First Year as a Doctor.
Chapter: Plastic Surgery: More than Noses and Breasts
Ariyan SEditors: M. Ramsdell.Walker Publishing Co., New York, NY1994
Sogo Igakusha (Japanese Edition)
Ariyan STokyo1993
Bone Grafts & Bone Subtitutes.
Chapter: The Role of Periosteum in Bone Grafting
Ariyan S, Burstein FDEditors: M.B. Habal, and A.H. Reddi.M.B. Habal, and A.H. Reddi, Philadelphia, PA1992
Plastic Surgery - Principles and Practice
Chapter: Microvascular Surgery of the Upper Extremity
Stahl RS, Ariyan SCV Mosby, St. Louis, MO1990
Plastic Surgery
Chapter: Cancer of the Upper Aerodigestive Tract
Ariyan S, Chicarilli ZNEditors: J McCarthy.WB Saunders, Philadelphia, PAEdition 3rd,1990
Plastic Surgery - Principles and Practice
Chapter: Neoplasia
Ariyan SCV Mosby, St. Louis, MO1990
Plastic Surgery - Principles and Practice
Chapter: Neoplasia of the Head and Neck
Ariyan SCV Mosby, St. Louis, MO1990
Plastic Surgery - Principles and Practice
Chapter: Malignant Melanoma
Ariyan SCV Mosby, St. Louis, MO1990
Grabb's Encyclopedia of Flaps
Chapter: Sternocleidomastoid Muscle and Musculocutaneous Flap
Ariyan SEditors: B Stranick, LO Vasconez, EJ Shall-Findlay.Little Brown & Co., Boston, MA1990
Grabb's Encyclopedia of Flaps
Chapter: Pectoralis Major Muscle and Musculocutaneous Flap
Ariyan SEditors: B Stranick, LO Vasconez, EJ Shall-Findlay.Little Brown & Co., Boston, MA1990
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Lectures

Diagnosis & Treatment of Pregnancy-Related Cancers in Women: Pregnancy, Fertility & Beyond
Yale CME, New Haven, Connecticut - 6/8/2012
14th Therapeutic ERCP-EUS Workshop
Yale CME, New Haven, Connecticut - 3/23/2012
Yale Cancer Center Evening Oncology Series: Melanoma
Yale CME, New Haven, Connecticut - 3/15/2012
104. Consensus Panel Report: “Prophylactic Antibiotics in Plastic Surgery.”
San Francisco, CA - 1/16/2012
Advances in the Surgical Management of Melanoma
San Francisco, CA - 1/9/2006
Advances in the Surgical Management of Melanoma.
San Juan, Puerto Rico - 1/17/2005
Considerations in the Surgical Management of Melanoma.
San Francisco, CA - 1/1/1999
Advances in Head and Neck Surgery in the Last Quarter of the Twentieth Century.
New Orleans, LA - 1/1/1999
Surgical Management of Malignant Melanoma.
Boston, MA - 1/1/1998
Restructuring Academic Departments of Surgery
Chicago, IL - 1/1/1998
Surgical Considerations in Malignant Melanoma.
Montreal, Canada - 1/1/1995
Advances in Management of Malignant Melanoma.
San Diego, CA - 1/1/1994
Alternatives for Cutaneous Covering.
Caracas, Venezuela - 1/1/1994
Surgical Reconstruction for Advanced Cancer of the Head and Neck.
Caracas, Venezuela - 1/1/1994
Treatment of Malignant Melanoma.
Caracas, Venezuela - 1/1/1994
Reconstruction of the Difficult Wounds of the Head and Neck
Memorial Sloan-Kettering Cancer Center, New York, NY - 1/1/1991
Reconstruction of the Jaw.
Hopital General Gregorio Maranon, University of Madrid, Madrid, Spain - 1/1/1991
Functional Neck Dissection
Hopital General Gregorio Maranon, University of Madrid, Madrid, Spain - 1/1/1991
Reconstruction of the Head and Neck with Myocutaneous Flaps.
Hopital General Gregorio Maranon, University of Madrid, Madrid, Spain - 1/1/1991
Considerations in Surgical Management of Malignant Melanoma.
Boston, MA - 1/1/1990
Head and Neck Reconstruction.
1/1/1989
The Effect of Periosteum in Bone Grafts.
Tampa, FL - 1/1/1989
Reconstruction of Oral Defects Following Glossectomy.
Atlanta, GA - 1/1/1989
Reconstruction of the Breast
Bangkok, Thailand - 1/1/1987
Functional Radical Neck Dissection
Princess Alexandra Hospital - University of Queensland, Brisbane, Australia - 1/1/1986
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Other

Resection & Reconstruction of Auricular Concha & Antitragus.
Ariyan S, Patel A, Instructional Video
1/1/2015
Functional Radical Neck Dissection.
Ariyan S, Patel A, Instructional Video
1/1/2015
Draping and Prepping for Head and Neck Surgery.
Ariyan S, Patel A, Instructional Video
1/1/2015
Double-Advancement Scalp Flaps.
Ariyan S, Patel A, Instructional Video
1/1/2015
Cervical Intramuscular Intransit Metastatic Melanoma.
Ariyan S, Clune J, Instructional Video
1/1/2014
V-Y Plantar Fasciocutaneous Flap.
Ariyan S, Instructional Video
1/1/2014
Parotidectomy for Primary Tumor.
Ariyan S, Teng E, Instuctional DVD
1/1/2013
Plantar Flap at Heel.
Ariyan S, Instuctional DVD
1/1/2012
Nasal Tip Reconstruction with Modified Reiger Nasalis Musculocutaneous Flap.
Ariyan S, Instuctional DVD
1/1/2011
Transverse Cervical Platysma Musculocutaneous Flap for Cheek Reconstruction.
Ariyan S, Instuctional DVD
1/1/2011
Securing Nasotracheal Anesthesia Tubes
Ariyan S, Instuctional DVD
1/1/2010
Superficial Parotidectomy with Dissection of Facial Nerve and Functional Radical Neck Dissection.
Ariyan S, Instuctional DVD
1/1/2010
Trapezius V-Y Musculocutaneous Flap.
Ariyan S, Instuctional DVD
1/1/2010
Radical Neck Dissection with Nerve Graft, Radical Axillary Dissection
Ariyan S, Instuctional DVD
1/1/2010
Melanoma of Chin with Zone I SLN
Ariyan S, Instuctional DVD
1/1/2010
Z-incision Functional Radical Neck Dissection with Submandibular Triangle
Ariyan S, Instuctional DVD
1/1/2009
V-Y Cheek Advancement Flap.
Ariyan S, Instuctional DVD
1/1/2009
Rhomboid Flap Reconstruction for Resection of Trunk
Ariyan S, Instuctional DVD
1/1/2009
L-incision Functional Radical Neck Dissection.
Ariyan S, Instuctional DVD
1/1/2009
Isolated Perfusion of Leg with Chemotherapy.
Ariyan S, Instuctional DVD
1/1/2009
Isolated Perfusion of Arm with Chemotherapy.
Ariyan S, Instuctional DVD
1/1/2009
Ear Helix Excision and Composite Flap Reconstruction.
Ariyan S, Instuctional DVD
1/1/2009
Ear and Cheek Resections under Local Anesthesia.
Ariyan S, Instuctional DVD
1/1/2009
Cross-lip Flap.
Ariyan S, Instuctional DVD
1/1/2009
Inguinal-Femoral Lymph Node Dissection – II
Ariyan S, Instuctional DVD
1/1/2008
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Press Mentions

Stephan Ariyan, MD, Named a Lifetime Achiever by Marquis Who's WhoSeptember 7th, 2017
Immune System, Unleashed by Cancer Therapies, Can Attack OrgansDecember 5th, 2016
How Plastic Surgeons Are Advancing Skin Cancer TreatmentMay 15th, 2018