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Office
710 Westwood Plaza
Los Angeles, CA 90095Phone+1 310-825-5521
Summary
- S. Thomas Carmichael is a neurologist and neuroscientist in the Departments of Neurology and of Neurobiology at the David Geffen School of Medicine at UCLA. Dr. Carmichael is Professor and Chair of the Department of Neurology, co-Director of the UCLA Broad Stem Cell Center and co-Director of the Regenerative Medicine Theme in the David Geffen School of Medicine. He has active laboratory and clinical interests in stroke and neurorehabilitation and how the brain repairs from injury. He received his M.D. and Ph.D. degrees from Washington University School of Medicine in 1993 and 1994, and completed a Neurology residency at Washington University School of Medicine, serving as Chief Resident. Dr. Carmichael was a Howard Hughes Medical Institute postdoctoral fellow at UCLA from 1998-2001. He has been on the UCLA faculty since 2001. Dr. Carmichael’s laboratory studies the molecular and cellular mechanisms of neural repair after stroke and other forms of brain injury. This research focuses on the processes of axonal sprouting and neural stem cell and progenitor responses after stroke, and on neural stem cell transplantation. Dr. Carmichael is an attending physician on the General Neurology and outpatient clinical services at UCLA.
Dr. Carmichael has published important papers on stroke recovery that have defined mechanisms of plasticity and repair. These include the fact that the stroke produces partially damage circuits that limit recovery, but can be restored to normal functioning with newly applied experimental drugs. His work has identified a novel brain “growth program” that is activated by stroke and leads to the formation of new connections. These studies have also identified how this growth program changes with age, and how specific molecules in the aged brain block the formation of new connections and of recovery.
Education & Training
- UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Neurorehabilitation, 1998 - 2001
- Washington University/B-JH/SLCH ConsortiumResidency, Neurology, 1995 - 1998
- Washington University/B-JH/SLCH ConsortiumInternship, Internal Medicine, 1994 - 1995
- Washington University in St. Louis School of MedicineClass of 1994
Certifications & Licensure
- CA State Medical License 1998 - 2025
- American Board of Psychiatry and Neurology Neurology
Awards, Honors, & Recognition
- American Association of Physicians https://aap-online.org/
- Viste Award American Society Society for Neurorehabilitation, 2019
- Javitz Neuroscience Award, National Institute of Neurological Disease and Stroke, 2018
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Publications & Presentations
PubMed
- 25 citationsEngineered HA hydrogel for stem cell transplantation in the brain: Biocompatibility data using a design of experiment approach.Lina R. Nih, Pouria Moshayedi, Irene L. Llorente, Andrew R. Berg, Jessica K Cinkornpumin
Data in Brief. 2017-02-01 - 122 citationsInjection of Microporous Annealing Particle (MAP) Hydrogels in the Stroke Cavity Reduces Gliosis and Inflammation and Promotes NPC Migration to the Lesion.Lina R. Nih, Elias Sideris, S. Thomas Carmichael, Tatiana Segura
Advanced Materials. 2017-06-26 - 35 citationsInjectable and Spatially Patterned Microporous Annealed Particle (MAP) Hydrogels for Tissue Repair Applications.Nicole J. Darling, Elias Sideris, Naomi Hamada, S. Thomas Carmichael, Tatiana Segura
Advanced Science. 2018-10-11
Lectures
- Tau Pathmeta Mathmeta:The Suffered is the Learned in Neural Repair after StrokeLos Angeles, CA - 2/14/2014
- Overview and IntroductionLos Angeles, CA - 2/11/2014
- Neural Progenitor Biology and White Matter Repair after Subcortical StrokeLos Angeles, CA - 2/12/2014
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Press Mentions
- Researchers Aim to Improve Stroke Recovery with New Granular BiomaterialsFebruary 4th, 2022
Grant Support
- Mechanisms Of Axonal Sprouting And Recovery In Intracerebral HemorrhageNational Institute Of Neurological Disorders And Stroke2012
- Translational Neuroscience Training GrantNational Institute Of Neurological Disorders And Stroke2009–2012
- Mechanisms Of Neural Repair In White Matter StrokeNational Institute Of Neurological Disorders And Stroke2010–2011
- Stroke Stem Cell/Hydrogel TherapyNational Institute Of Neurological Disorders And Stroke2009–2010
- Neural Repair After StrokeNational Center For Research Resources2009–2010
- Mechanisms Of Neuronal Regeneration After Stroke In A Novel Neurovascular NicheNational Institute Of Neurological Disorders And Stroke2006–2010
- Mechanisms Of Axonal Sprouting After StrokeNational Institute Of Neurological Disorders And Stroke2004–2007
Professional Memberships
- Member
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