SolomonI.HamburgMD

Oncology • Beverly Hills, CA

Breast Cancer, Hematologic Oncology, Thoracic Cancer

Oncology/UCLA Health/Clinical Professor of Medicine

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Office
UCLA Health
120 S Spalding Dr.
Beverly Hills, CA 90212
Phone+1 310-205-0771

Summary

General Hematology, Clotting, Anemia, Myelodysplasia, Myeloproliferative disorders, Acute and chronic leukemia, lymphoma,
Oncology: Lung ca, mesothelioma, GI malignancies, Hepatocellular carcioma, GU malignancies, Breast cancer, Prostate cancer

Education & Training

UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Hematology and Medical Oncology, 1984 - 1987
New York Presbyterian Hospital (Cornell Campus)Residency, Internal Medicine, 1981 - 1984
New York UniversityMD-PhD, Cell Biology, 1974 - 1981
New York UniversityPh.D., Basic Medical Sciences, 1973 - 1981
New York University School of MedicineClass of 1981, MD-PhD, Alpha Omega Alpha
New York UniversityMaster of Science, Cell Biology, 1976 - 1978

Certifications & Licensure

CA State Medical License 1984 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

Healing Award Tower Cancer Research Foundation, 2013
Alpha Omega Alpha New York University, 1981
CMS Meaningful Use Stage 1 Certification ARIA Radiation Oncology EMR, Varian Medical Systems, 2013
Top MD Consumers Checkbook
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Clinical Trials

Eribulin Mesylate in Treating Patients With Locally Advanced or Metastatic Cancer of the Urothelium and Kidney Dysfunction Start of enrollment: 2006 Oct 23
Active, not recruiting
Phase 1, Phase 2
Vorinostat and Rituximab in Treating Patients With Indolent Non-Hodgkin Lymphoma Start of enrollment: 2008 Jul 23
Completed
Phase 2
Studying Blood and Tumor Tissue Samples in Women With Invasive Breast Cancer, Ductal or Lobular Carcinoma in Situ, or Benign Breast Disease Start of enrollment: 2005 Aug 01
Completed
Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors Start of enrollment: 2009 Jun 01
Completed
Phase 2
Irinotecan Hydrochloride With or Without Alvocidib in Treating Patients With Advanced Stomach or Gastroesophageal Junction Cancer That Cannot Be Removed By Surgery Start of enrollment: 2009 Sep 01
Completed
Phase 2
Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus Start of enrollment: 2010 Jan 01
Terminated
Phase 2
Gemcitabine Hydrochloride With or Without Vismodegib in Treating Patients With Recurrent or Metastatic Pancreatic Cancer Start of enrollment: 2009 Sep 01
Completed
Phase 1, Phase 2
Selumetinib With or Without Temsirolimus in Treating Patients With Metastatic, Recurrent, or Locally Advanced Soft Tissue Sarcoma That Cannot Be Removed By Surgery Start of enrollment: 2010 Oct 01
Completed
Phase 2
MK2206 in Treating Patients With Advanced Liver Cancer That Did Not Respond to Previous Therapy Start of enrollment: 2010 Dec 01
Terminated
Phase 2
Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery Start of enrollment: 2011 Jan 18
Completed
Phase 2
Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer Start of enrollment: 2010 Dec 01
Terminated
Phase 2
MK2206 and Erlotinib Hydrochloride in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Progressed After Previous Response to Erlotinib Hydrochloride Therapy Start of enrollment: 2011 Feb 01
Completed
Phase 2
Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery Start of enrollment: 2011 Jun 20
Active, not recruiting
Phase 1, Phase 2
Chemotherapy Plus Cetuximab in Combination With VTX-2337 in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Start of enrollment: 2013 Oct 14
Completed
Phase 2
Phase II Study to Evaluate Overall Response in Patients With Higher Risk Myelodysplastic Syndromes (MDS) Treated With Azacitidine With or Without Deferasirox. Start of enrollment: 2014 Sep 11
Terminated
Phase 2
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Publications & Presentations

PubMed

7 citations
Safety and Efficacy of Ruxolitinib in Patients With Myelofibrosis and Low Platelet Counts (50–100 × 109/L): Final Analysis of an Open-label Phase 2 study
Moshe Talpaz, Josef T. Prchal, Lawrence B. Afrin, Murat O. Arcasoy, Solomon I. Hamburg
Clinical Lymphoma, Myeloma & Leukemia. 2021-11-02
81 citations
Interim analysis of safety and efficacy of ruxolitinib in patients with myelofibrosis and low platelet counts
Moshe Talpaz, Ronald Paquette, Lawrence B. Afrin, Solomon I. Hamburg, Josef T. Prchal
Journal of Hematology & Oncology. 2013-10-29
11 citations
Heart transplantation using bivalirudin as anticoagulant.
Sinan Simsir, Ernst R. Schwarz, Lawrence S.C. Czer, Solomon I. Hamburg
Interactive Cardiovascular and Thoracic Surgery. 2010-01-01

Journal Articles

Interim analysis of safety and efficacy of ruxolitinib in patient with myelofibrosis and low platelet counts
Talpaz, M, Paquette, R, Afrin, L, Hamburg, S.I., et. al, J Hematology and Oncology, 1/1/2013
Heart transplantation using bivalirudin as anticoagulant
Simsir SA, Schwarz ER, Czer LS, Hamburg SI, Interact Cardiovasc Thorac Surg, 1/1/2010
Laparoscopic splenectomy for hairy cell leukemia in pregnancy
Adeniji BA, Fallas M, Incerpi M, Hamburg S, Datz R, Ogunyemi D, Case Report Med, 1/1/2010
Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double - blind randomized controlled trial
Kuter, D.J., Bussel, J.B., Lyons, R.M., Pullarkat, V., Gernsheimer, T.B., Senecal, F.M., Aldedort, L.M., Geroge, J.N., Kessler, C.M., Sanz, M.A. Liebman, H. A., Slovic..., Lancet, 1/1/2008
Phase II trial of nolatrexed dihdrochloride [Thymitaq, AG337] in patients with advanced hepatocellular carcinoma
Jhawer M, Rosen L, DanceyJ, Hochster H, Hamburg S, Tempero M, Clendeninn N, Mani S, Invest New Drugs, 1/1/2007
Phase II multicenter study of induction chemotherapy followed by concurrent efaproxiral (RSR13) and thoracic radiotherapy for patients with locally advanced non-small-...
Choy H, Nabid A, Stea B, Scott C, Roa W, Kleinberg L, Ayoub J, Smith C, Souhami L, Hamburg S, Spanos W, Kreisman H, Boyd AP, Cagnoni PJ, Curran WJ, J Clin Oncol, 1/1/2005
Splenic Infarction Associated with Anti-Cardiolipin Antibody: A Report of Two Cases, Cedars-Sinai Medical Center, Los Angeles, CA
Carie L. McVay, MD, Yibin Zhang, MD, Albert Ko, MD, Solomon I. Hamburg MD, PhD, Leslie Memsic, MD, Leon Morgenstern, MD, Allan W. Silberman, MD, PhD, Am Surg, 1/1/2004
Technetium-99m Sestamibi Scanning Reflects Marrow Activity in a B-Thalassemia Patient Treated with an Allogeneic Bone Marrow Transplant
Look, R.M., Koh, H.A., Hamburg, S.I., Lim, S.W., Waxman, A.D., Jochelson, M.S., Gupta, P.K., Fuerst, M.P., Kusuanco, D.A., Lawrence, G.N., and Giles, F.J., Hematology, 1/1/1996
Mononuclear phagocytes: Responders to and producers of interferon
Hamburg, S.I., Fleit H.B., Unkeless, J., and Rabinovitch M., Annals of the New York Academy of Science, 1/1/1980
Relationship between enhanced macrophage phagocytic activity and the induction of interferon by Newcastle disease virus in mice
Hamburg, S.I., Cassell, G.H., and Rabinovitch, M., J Immunol, 1/1/1980
Interferon induced enhancement of Fc mediated phagocytosis
Rabinovitch, M., Hamburg, S.I., and Fleit, H.B., J Reticuleondoth Soc, 1/1/1980
Interferon-induced enhancement of Fc Receptor-mediated macrophage phagocytosis
Rabinovitch, M, Hamburg S.I., Fleit, H.B., J Reticuloendothelial Soc, 1/1/1980
Serum interferon and phagocytic activity of macrophages in recombinant inbred mice inoculated with Newcastle disease virus
Manejias, R.E., Hamburg, S.I., and Rabinovitch, M, Cell Immunol, 1/1/1978
Macrophage activation: Increased ingestion of IgG-coated erythrocytes after administration of interferon inducers to mice
Hamburg, S. I., Manejias, R.E., and Rabinovitch, M., J Exp Med, 1/1/1978
Bonding in divalent transition metal cyanides Crystal structure of dicesium, magnesium hexacyanoferrate (II)
Swanson, B.I., Hamburg, S.I., and Ryan, R.R., Inorg Chem, 1/1/1974
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Books/Book Chapters

Medical Screening for California Law Enforcement, 1993.
Chapter: Chapter V, Hematology
Hamburg, S.I.,Liebman, H.and Weitz, E.1993
Medical Screening for California Law Enforcement, 1993.
Chapter: Chapter VI, Oncology.
Hamburg, S.I.,Liebman, H.and Weitz, E.1993
Guide to Dental Problems for Physicians and Surgeons.
Chapter: Hemorrhagic Disorders.
Hamburg, S.I. and Rosove, M.Editors: S.R. Thaller and W.W. Montgomery.1988
Mononuclear Phagocytes, Functional Aspects.
Chapter: Macrophage activation by interferon or interferon inducers. Chapter 59
Page 1515 - 1538Rabinovitch, M. and Hamburg, S.I.Hague, the Netherlands1980
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Abstracts/Posters

Abstract LB-289: A phase I dose escalation study of TKM-080301, a RNAi therapeutic directed against PLK1, in patients with advanced solid tumors.
Ramesh K. Ramanathan, Solomon I. Hamburg, Mitesh J. Borad, Mahesh Seetharam, Madappa N. Kundranda, Peter Lee, Paul Fredlund, Mark Gilbert, Cathy Mast, Sean C. Semple, ..., AACR, 1/15/2013
Preliminary Safety and Efficacy from a Phase II study of Ruxolitinib in Patients with Primary and Secondary Myelofibrosis with Platelet Counts of 50-100x109/L.
Moshe Talpaz, Solomon I. Hamburg, Ktarzyna Jamieson, Howard R. Terebelo, Lawrence Afrin, Elliott F. Winton, Michael A. Scola, Roger M. Lyons, Jimmie Huling Harvey Jr.,..., ASCO, 1/1/2012
Results of a phase 1 dose-escalation study of once-weekly MLN9708, an investigational proteasome inhibitor, in patients with relapsed/refractory lymphoma.
Sarit E. Assouline, Julie Chang, Bruce D. Cheson, Robert Rifkin, Solomon Hamburg, Ruben Reyes, Ai-Min Hui, Jiang Yu, Neeraj Gupta, Alessandra Di Bacco, Yaping Shou, P..., ASCO, 1/1/2012
Survival Benefit of Nolatrexed (THYMITAQ) n Advanced Hepatocellular Carcinoma (aHCC)
Hamburg, S; Miller, W, Garcia-Vargas J; Joseph, L; Gunwale, L.F.; Horan, J., ASCO, 1/1/2003
Phase II Study of Amifostine for the Treatment of the Myelodysplastic Syndrome.
Kemp in, S., Spirit, G., Cache, G., Irwin, D., Gee, T., Stephan, D., Blum, R., Hamburg, S.I., Wilson, E., ASCO, 1/1/1998
High Dose Chemotherapy (CTX) with Autologous Peripheral Stem Cell Transplantation (PSCT) for Advanced Sarcoma.
Myong, H., Rosen, G., Forscher, C., Hurvitz, C., Hamburg, S.I., Qasabian, L., Pepkowitz, S., Lill, M., Giles, F.J., ASCO, Cedars-Sinai Medical Center, Los Angeles, CA, 1/1/1998
Chemoembolization and Transplantation
Colquhoun, S.D., Ghobrial, R.M., Sue, P., Goss, J.A., Aranout, W.S., Parkasi, A., Friedman, M., Gomes, A.S., Rosove, M.H., Hamburg, S.I.,Shackelton, C.S., Busuttil, R.W., American Society of Transplant Surgeons, 1/1/1997
Technetium-99m, MIBI scanning in multiple myeloma (MM).
Durie, B.M.G., Waxman, A.D., Jochelson, M., Giles, F.J., Hamburg, S.I. and Avedon, M., ASCO, 1/1/1996
MGBG therapy of relapsed extra lymphatic HIV-associated non-Hodgkin's lymphoma (HIV NHL).
Lim, S.W., Look, R.M., Bick, A.B., Hamburg, S.I., Lawrence, G.N., Fuerst, M.P., Kusuanco, D.A., Kessler, C.E. and Giles, F.J., ASCO, 1/1/1995
Peripheral blood stem cell (PBSC) yields following nitrosourea-containing and nonequivalent engraftment times post-myeloablative therapy.
Look, R.M., Lim, S.W., Fuerst, M.P., Jacobs, A.G., Pepkowitz, S.H., Goldfinger, D., Klohn, J.L., Decker, R.W., Hamburg, S.I., Moss, T.J., Hurvitz, C.H., Lawrence, G.N...., ASCO, 1/1/1995
Utility of methoxyiso-butylisonitrile (MIBI) imaging in multiple myeloma (MM) patients undergoing peripheral blood stem cell (PBSC) transplant.
Look, R.M., Lim, S.W., Waxman, A.D., Jochelson, M.S., Hamburg, S.I., Decker, R.W., Fuerst, M.P., Lawrence, G.N., Kusuanco, D.A., Kessler, C.E. and Giles, F.J., ASCO, 1/1/1995
Monitoring of chemo-purging of harvested marrow using a clonogenic assay for patients with acute lymphoblastic leukemia.
Moss, T.J., Hamburg, S.I., Decker, R.W., and Hurvitz, C., Proceedings American Society of Clinical Oncology, 1/1/1993
Lack of evidence for early autologous bone marrow transplantation in high-risk lymphoma patients.
Hamburg, S.I., Decker, R.W., Moss, T.J. and Hermits, C., ASH Proceedings, 1/1/1992
Phase II study of high dose continuous infusion dimethyl triazeno imidazole carboxamide (DTIC) in metastatic leiomyosarcoma (LMS).
Rosen, G., Chawla, S., Hamburg, S.I., and Lowenbraun, S., ASCO, 1/1/1990
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Lectures

Update in Therapy for P. Vera and Myelofibrosis
Cedars-Sinai Medical Center, Los Angeles, CA - 1/15/2016
Myelofibrosis 2014
Cedars-Sinai Medical Center, Los Angeles, CA - 1/26/2014
The Big Spleen: New diagnostic and management considerations. Myeloproliferative disorders.
Marina Del Rey, CA - 1/21/2012
Cholangiocarcinomas, Systemic Therapies
Cedars-Sinai Medical Center, Los Angeles, CA - 1/1/2012
Thrombocytopenia and Thrombopoiesis Megakaryocyte Development and Pathology, Thrombopoietin Regulation.
Cedars-Sinai Medical Center, Los Angeles, CA - 1/11/2010
Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial.
Massachusetts General Hospital, Boston, MA - 1/1/2008
Phase II trial of nolatrexeddihydrochloride" [Thymitaq, AG 337| in patients with advanced hepatocellular carcinoma.
Montefiore Medical Center, New York, NY - 1/1/2006
Phase II multicenter study of induction chemotherapy followed by concurrent efaproxiral (RSR13) and thoracic radiotherapy for patients with locally advanced non-small-...
Vanderbilt University Medical Center, Nashville, TN - 1/1/2005
Splenic infarction associated with anti-cardiolipin antibody: a report of two cases.
Cedars-Sinai Medical Center, Los Angeles, CA - 1/1/2004
Hepatoma Update 2003
Cedars-Sinai Medical Center, Los Angeles, CA - 1/1/2003
Cancer and the Workplace
Mount San Antonio College, West Covina, CA - 1/1/2002
Hematological Emergencies
Cedars-Sinai Medical Center, Los Angeles, CA - 1/1/2002
Malignancy and Solid Organ Transplantation
Cedars-Sinai Medical Center, Los Angeles, CA - 1/1/2001
Non-myeloablative transplantation
Cedars-Sinai Medical Center, Los Angeles, CA - 1/1/2000
Matrix Metallo-Proteases and Cancer
Cedars-Sinai Medical Center, Los Angeles, CA - 1/1/2000
Coagulation Disorders
Cedars-Sinai Medical Center, Los Angeles, CA - 1/1/1999
Novel Therapeutic Approaches for Unresectable Malignancies
Cedars-Sinai Medical Center, Los Angeles, CA - 1/1/1997
Transfusion Therapy
Cedars-Sinai Medical Center, Los Angeles, CA - 1/1/1995
Interferon in Chronic Myelogenous Leukemia
Detroit, MI - 1/1/1993
Interferon induced activation of macrophage
New York, NY - 1/1/1980
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