Overview of Dr. Mantha
I am a clinical hematologist with special interests in cancer-associated disorders of hemostasis, genomics, big data and machine learning. My recent work includes an assessment of cancer-specific genetic alterations modulating the risk of thromboembolism, and application of this knowledge to predict clinical events using random survival forests. In the last year I have also developed CEDARS, a simple and efficient pipeline for electronic health record annotation.
Office
530 East 74th Street
New York, NY 10021
Education & Training
- Harvard UniversityMPH, Public Health, 2010
- Yale-New Haven Medical CenterFellowship, Blood Banking/Transfusion Medicine, 2005 - 2006
- New York Presbyterian Hospital (Cornell Campus)Fellowship, Hematology and Medical Oncology, 2002 - 2005
- Laval UnivClass of 1999
Certifications & Licensure
- FL State Medical License 2022 - Present
- NJ State Medical License 2018 - 2025
- NY State Medical License 2012 - 2025
- CT State Medical License 2024 - 2024
- MA State Medical License 2006 - 2012
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Hematology
- American Board of Pathology Blood Banking/Transfusion Medicine
Publications & Presentations
PubMed
- 1 citationsDNA liquid biopsy-based prediction of cancer-associated venous thromboembolism.Justin Jee, A Rose Brannon, Rohan Singh, Andriy Derkach, Christopher Fong
Nature Medicine. 2024-09-01 - 338 citationsCancer therapy shapes the fitness landscape of clonal hematopoiesisKelly L. Bolton, Ryan Ptashkin, Teng Gao, Lior Z. Braunstein, Sean M. Devlin
Nature Genetics. 2020-10-26 - 70 citationsDeterminants of fatal bleeding during induction therapy for acute promyelocytic leukemia in the ATRA eraSimon Mantha, Debra A. Goldman, Sean M. Devlin, Ju Whei Lee, Diana Zannino
Blood. 2014-12-06
Abstracts/Posters
- Extended Mutational Profiling By MSK-IMPACTTM Identifies Mutations Predicting Thromboembolic Risk in Patients with Solid Tumor MalignancyClinically Relevant AbstractSimon Mantha, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Lectures
- Hypofibrinogenemia and Disseminated Intravascular Coagulation Rarely Complicate Treatment-Naive Acute Lymphoblastic Leukemia2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Cancer-Associated Thrombosis: Anatomic Distribution of the Index Event Is Not a Reliable Predictor of Recurrence Risk2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Press Mentions
- MSK Research Highlights, September 3, 2024September 3rd, 2024
Professional Memberships
- Member
Other Languages
- French, Spanish
Industry Relationships
- Organizing Member, Daboia Consulting LLC2018 - Present
External Links
- Clinical Event Detection and Recording Systemhttp://cedars.io
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