ShaunWilliamJacksonMD

Pediatric Nephrology • Seattle, WA

Pediatric Glomerular Disease Nephrology

Associate Professor, Pediatrics, University of Washington School of Medicine

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Office
4800 Sand Point Way NE
# Seattle
Seattle, WA 98105
Phone+1 857-891-6790

Education & Training

University of WashingtonFellowship, Pediatric Rheumatology, 2009 - 2012
University of WashingtonFellowship, Pediatric Nephrology, 2008 - 2009
Boston Children’s Hospital/Boston Medical CenterResidency, Pediatrics, 2005 - 2008
University of Cape Town Faculty of MedicineClass of 2001

Certifications & Licensure

WA State Medical License 2008 - 2025
American Board of Pediatrics Pediatric Nephrology
American Board of Pediatrics Pediatric Rheumatology

Awards, Honors, & Recognition

Postdoctoral fellow poster prize University of Washington, 2013
Arnold Lee Smith Endowed Professorship for Research Faculty Development 2013
Outstanding Presentation Award Seattle Children’s Fellow and Resident Research Day, 2012
Distinguished Fellow Award American College of Rheumatology (ACR), 2012
Fellow teaching award Seattle Children’s Hospital, 2009
Best oral presentation, Young Investigator Award Session Asia Pacific Association for the Study of the Liver, 2004
Medicine Class Medal 2001
JH Louw Prize 2001
Barnard Fuller Prize 2001
Jack Prisman Prize 2001
Surgery Class Medal 2001
University Gold Medal 2001
Medal SA Society of Anaesthetists, 2000
Moffat Memorial Prize 2000
Berk Silber Prize 2000
Psychiatry Class Medal 2000
Cuthbert Crichton Obstetrics Prize 1999
Anatomical Pathology Class Medal 1998
Poliomyelitis Research Foundation Award 1998
Stanley Phillip Neumann Memorial Award 1998
Chemical Pathology Class Medal 1998
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Clinical Trials

REACT-01: Reversing Autoimmunity Through Cell Therapy Start of enrollment: 2024 Jul 01
Not yet recruiting
Phase 1
Roles: Study Chair, Contact

Publications & Presentations

PubMed

Hypomorphic RAG2 Deficiency Promotes Selection of Self-Reactive B Cells.
Christopher D Thouvenel, Christopher M Tipton, Yasuhiro Yamazaki, Ting-Ting Zhang, Stacey Rylaarsdam
Journal of Clinical Immunology. 2025-01-15
Childhood-onset lupus nephritis is characterized by complex interactions between kidney stroma and infiltrating immune cells.
Patrick Danaher, Nicholas Hasle, Elizabeth D Nguyen, Jordan E Roberts, Natalie Rosenwasser
Science Translational Medicine. 2024-11-27
10 citations
Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity.
Aaron Bodansky, David Jl Yu, Alysa Rallistan, Muge Kalaycioglu, Jim Boonyaratanakornkit
The Journal of Clinical Investigation. 2024-05-16

Journal Articles

Integrated B Cell, Toll-like, and BAFF Receptor Signals Promote Autoantibody Production by Transitional B Cells
David J Rawlings, Shaun W Jackson, The Journal of Immunology
B cells take the front seat: Dysregulated B cell signals orchestrate loss of tolerance and autoantibody production
Jackson SW, Kolhatkar N, Rawlings DJ, Current Opinion in Immunology, 1/10/2015
Opposing impact of B cell intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation
Jackson SW, Scharping NE, Kolhatkar N, Khim S, Schwartz MA, Li QZ, Hudkins KL, Alpers CE, Liggitt D, Rawlings DJ, J Immunol, 1/1/2014
The PTPN22 Risk Variant Promotes Systemic Autoimmunity in Murine Models
Dai X, James R, Habib T, Singh S, Jackson SW, Khim S, Moon RT, Liggitt D, Wolf-Yadlin A, Buckner JH, Rawlings DJ, J. Clin. Invest, 1/1/2013
Trypanosoma cruzi Trans-sialidase initiates a Program Independent of the Transcription Factors ROR-gammat and Ahr that leads IL-17 Production by Activated B Cells
Bermejo DA, Jackson SW, Gorosito-Serran M, Acosta-Rodriguez EV, Amezcua-Vesely MC, Sather BD, Singh AK, Khim S, Liggitt D, Mucci J, Campetella O, Oukka M, Gruppi A, R..., Nature Immunology, 1/1/2013
Cutting Edge: Regulation of TLR4-driven B cell Proliferation by RP105 is not B cell-autonomous
Allen JL, Flick LM, Divanovic S, Jackson SW, Bram R, Rawlings DJ, Finkelman FD, Karp CL, J Immunol, 1/1/2012
WASp Deficient B Cells Play a Critical, Cell Intrinsic Role in Triggering Autoimmunity
Becker-Herman S, Meyer-Bahlburg A, Schwartz MA, Jackson SW, Panigrahi AK, Hudkins KL, Liu C, Sather BD, Khim S, Liggitt D, Song W, Silverman GJ, Luning Prak ET, Alpers..., J Exp Med, 1/1/2011
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Books/Book Chapters

Pocket Pediatrics
Chapter: Hyponatremia
Jackson SWEditors: R. Vinci, MD & J. Moses, MD.PocketMedicine.com, Inc., New York, NYEdition 2nd,2009
Pocket Pediatrics
Chapter: Hypernatremia
Jackson SWEditors: R. Vinci, MD & J. Moses, MD.PocketMedicine.com, Inc., New York, NYEdition 2nd,2009
Pocket Pediatrics
Chapter: Hypokalemia
Jackson SWEditors: R. Vinci, MD & J. Moses, MD.PocketMedicine.com, Inc., New York, NYEdition 2nd,2009
Pocket Pediatrics
Chapter: Hyperkalemia
Jackson SWEditors: R. Vinci, MD & J. Moses, MD.PocketMedicine.com, Inc., New York, NYEdition 2nd,2009
Pocket Pediatrics
Chapter: Renal Tubular Acidosis
Jackson SWEditors: R. Vinci, MD & J. Moses, MD.PocketMedicine.com, Inc., New York, NYEdition 2nd,2009
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Abstracts/Posters

Opposing impact of B cell intrinsic TLR7 and TLR9 signals on autoantibody repertoire and systemic inflammation
Jackson SW, Scharping NE, Kolhatkar N, Khim S, Schwartz MA, Li QZ, Hudkins KL, Alpers CE, Liggitt D, Rawlings DJ, Pediatric Academic Societies (PAS), 1/1/2014
B Cell-Intrinsic Deletion of the Type 1 Interferon Receptor Does Not Impact the Development of Murine Lupus
Jackson SW, Jacobs H, Scharping NE, Khim S, Rawlings DJ, American College of Rheumatology (ACR) annual meeting, 1/1/2014
Trypanosoma cruzi trans-sialidase initiates an ROR-gt independent program leading to high-level IL-17 production by activated B cells
Bermejo DA, Jackson SW, Gorosito-Serran M, Acosta-Rodriguez EV, Amezcua-Vesely MC, Sather BD, Singh AK, Khim S, Liggitt D, Mucci J, Campetella O, Oukka M, Gruppi A, R..., Keystone Symposium, “B Cell Development and Function”, 1/1/2013
B cell intrinsic Toll-like receptor signals define the autoantibody repertoire of autoimmune-prone Wiskott-Aldrich syndrome chimeras
Jackson SW, Kolhatkar NS, Schwartz MA, Khim S, Rawlings DJ, Seattle Children’s Hospital Fellow’s Research Day, 1/1/2012
Marginal zone defects in Wiskott-Aldrich syndrome are dependent on B cell intrinsic TLR signals
Jackson SW, Kolhatkar NS, Schwartz MA, Khim S, Rawlings DJ, Federation of Clinical Immunology Societies meeting (FOCIS); American College of Rheumatology (ACR) annual meeting, 1/1/2012
WASp Deficient B Cells Play a Critical, Cell Intrinsic Role in Triggering Autoimmunity
Becker-Herman S, Meyer-Bahlburg A, Schwartz MA, Jackson SW, Panigrahi AK, Hudkins KL, Liu C, Sather BD, Khim S, Liggitt D, Song W, Silverman GJ, Luning Prak ET, Alper..., Keystone Symposium, “B Cells: New Insights into Normal versus Dysregulated Function”, 1/1/2011
The role of WASp deficient B cells in driving autoimmune disease and atherogenesis
Jackson SW, Becker-Herman S, Meyer-Bahlburg A, Schwartz MA, Panigrahi AK, Hudkins KL, Liu C, Sather BD, Khim S, Liggitt D, Song W, Silverman GJ, Luning Prak ET, Alper..., Seattle Children’s Hospital Fellow’s Research Day, 1/1/2011
Renal transplantation from a donor with undiagnosed Class V lupus nephritis demonstrates prolonged histopathologic features of lupus nephritis despite absence of SLE i...
Jackson SW, Finn LS, Okamura DM, McDonald RA, Pediatric Rheumatology Symposium, 1/1/2011
Decreased activity of endothelial alphaVBeta3 integrin in the Cd39-null mouse is associated with defective tumor angiogenesis
Jackson SW, Hoshi T, Sundberg C, Enjyoji K, Cszimadia E, Robson SC, 4th International Symposium of Nucleosides and Nucleotides. Purines, 1/1/2004
Disordered Liver Regeneration and Defective Angiogenesis in NTPDase1/Cd39-Null Mice
Jackson SW, Sun X, Cardenas A, Enjyoji K, Cszimadia E, Robson SC, Young Investigator Award Session. Asia Pacific Association for the Study of the Liver, 1/1/2004
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Press Mentions

Updates in Pediatric Lupus: Experts Discuss Advances in Lupus Nephritis Treatments, Monogenic Lupus & MoreAugust 31st, 2021
Lupus Research Alliance Awards $3 Million to Advance Pediatric Lupus Nephritis Diagnosis and TreatmentAugust 3rd, 2023
Seattle Children’s Set to Launch First U.S. CAR T-cell Clinical Trial for Children with LupusMarch 19th, 2024
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