Shahin Rafii MD
Hematologic Oncology, Myeloproliferative Disorder Hematology-Oncology, Sickle Cell & Other Anemias
Arthur B Belfer Professor of Genetic Medicine, Division Chief of Regenerative Medicine, Department of Medicine, Director Ansary Stem Cell Institute; Professor of Reproductive Medicine, Weill Cornell Medicine, New York, NY, Founder: Angiocrine Bioscience, San Diego, CA
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1300 York AveWeill Cornell Medical College, Room A-863New York, NY 10065
Phone+1 917-287-3801
Fax+1 212-746-8481
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Education & Training
New York Presbyterian Hospital (Cornell Campus)Fellowship, Hematology and Medical Oncology, 1989 - 1992- New York Presbyterian Hospital (Cornell Campus)Residency, Internal Medicine, 1986 - 1988
Albert Einstein College of MedicineClass of 1986
Certifications & Licensure
NY State Medical License 1987 - 2015
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2001
- Investigator Howard Hughes Medical Institute
Publications & Presentations
PubMed
- Coordinated differentiation of human intestinal organoids with functional enteric neurons and vasculature.Charlie J Childs, Holly M Poling, Kevin Chen, Yu-Hwai Tsai, Angeline Wu
Cell Stem Cell. 2025-03-04 - Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing.Tomer Itkin, Sean Houghton, Ryan Schreiner, Yang Lin, Chaitanya R Badwe
Nature Immunology. 2025-03-01 - Single-cell atlas of human pancreatic islet and acinar endothelial cells in health and diabetes.Rebecca Craig-Schapiro, Ge Li, Kevin Chen, Jesus M Gomez-Salinero, Ryan Nachman
Nature Communications. 2025-02-06
Journal Articles
- Catheter-Directed Intraportal Delivery of Endothelial Cell Therapy for Liver Regeneration: A Feasibility Study in a Large-Animal Model of CirrhosisKyungmouk Steve Lee, Shahin Rafii, David C. Madoff, David Li, Radiology
Abstracts/Posters
- Integrated Single Cell Transcriptomics Defines an Engineered Niche Supporting Hematopoietic Stem Cell Development Ex VivoShahin Rafii, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Transcription Factor Induction of Ectopic Vascular Blood Stem Cell Niches In VivoShahin Rafii, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Fli-1 Transcriptionally Integrates Microenvironmental Cues Sensing By Self-Renewing Hematopoietic Stem and Progenitor CellsShahin Rafii, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Press Mentions
‘Flipping’ Switch Boosts Stem Cell Numbers for TherapiesMarch 12th, 2025- FLIpping the Switch: Boosting Stem Cell Numbers for TherapiesMarch 10th, 2025
- Revolutionizing Type 1 Diabetes: Breakthrough in Islet Transplantation with Blood Vessel Cells Offers New HopeFebruary 22nd, 2025
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Grant Support
- Abnormal Extracellular Vesicles and Particles from Human Islets Impact T1D progressionWEILL MEDICAL COLL OF CORNELL UNIV2023–2028
- Abnormal Extracellular Vesicles and Particles from Human Islets Impact T1D progressionWEILL MEDICAL COLL OF CORNELL UNIV2023–2028
- Molecular Determinants of liver sinusoidal endothelial cells for hepatic regenerationWEILL MEDICAL COLL OF CORNELL UNIV2023–2028
- Abnormal Extracellular Vesicles and Particles from Human Islets Impact T1D progressionWEILL MEDICAL COLL OF CORNELL UNIV2023–2028
- Abnormal Extracellular Vesicles and Particles from Human Islets Impact T1D progressionWEILL MEDICAL COLL OF CORNELL UNIV2023–2028
- Abnormal Extracellular Vesicles and Particles from Human Islets Impact T1D progressionWEILL MEDICAL COLL OF CORNELL UNIV2023–2028
- Abnormal Extracellular Vesicles and Particles from Human Islets Impact T1D progressionWEILL MEDICAL COLL OF CORNELL UNIV2023–2028
- Adaptable tissue-specific endothelial cells for organ regenerationWEILL MEDICAL COLL OF CORNELL UNIV2020–2027
- Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapyWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Derivation of pancreatic islet-like organoids from human gastric stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapyWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Derivation of pancreatic islet-like organoids from human gastric stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Derivation of pancreatic islet-like organoids from human gastric stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapyWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapyWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapyWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Derivation of pancreatic islet-like organoids from human gastric stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapyWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Derivation of pancreatic islet-like organoids from human gastric stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Derivation of pancreatic islet-like organoids from human gastric stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapyWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Engineering islet-like organoids from gastric stem cells for T1D cell replacement therapyWEILL MEDICAL COLL OF CORNELL UNIV2022–2026
- Negative feedback regulation of growth factor signaling in adult spermatogonial stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2021–2026
- Methods for detection of dynamic intracellular signals in single adult spermatogonial stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2023–2025
- Investigating a master regulator of large intestine stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2021–2025
- Investigating a master regulator of large intestine stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2021–2025
- Investigating a master regulator of large intestine stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2021–2025
- Investigating a master regulator of large intestine stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2021–2025
- Investigating a master regulator of large intestine stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2021–2025
- Investigating a master regulator of large intestine stem cellsWEILL MEDICAL COLL OF CORNELL UNIV2021–2025
- Endothelial cell transplantation for multi-organ repair to counter radiation injuryWEILL MEDICAL COLL OF CORNELL UNIV2018–2025
- Endothelial cell transplantation for multi-organ repair to counter radiation injuryWEILL MEDICAL COLL OF CORNELL UNIV2018–2025
- Identification Of Vascular Inductive Signals In Liver RegenerationNational Institute Of Diabetes And Digestive And Kidney Diseases2012
- Contribution Of The Vascular Niche To The Hematopoietic Reconstitution.National Heart, Lung, And Blood Institute2009–2011
- Contribution Of Cxcr4+Vegfr1+ Hemangiogenic Progenitors To Lung RevascularizationNational Heart, Lung, And Blood Institute2007–2011
- Dynamic Regulation Of The Epigenome During Hematopoietic DifferntiationNational Heart, Lung, And Blood Institute2009–2010
- Reconstitution Of Thrombopoiesis By Angiogenic FactorsNational Institute Of Allergy And Infectious Diseases2009
- Therapy Of Thrombocytopenic Disorders By ChemokinesNational Heart, Lung, And Blood Institute2006–2007
- Vascular Heterogeneity Determination By Marrow Progenit*National Heart, Lung, And Blood Institute2004–2006
- Regulation Of Hemangiogenesis By Adenoviral E4 GenesNational Heart, Lung, And Blood Institute2002–2006
- Postnatal Angiogenesis And Marrow Derived Precursor CellNational Heart, Lung, And Blood Institute2001–2005
- Vascular Heterogeneity Determination /Marrow ProgenitorsNational Heart, Lung, And Blood Institute2003
- Bone Marrow Totipotent Stem Cells &Adenoviral VectorsNational Heart, Lung, And Blood Institute2000–2002
- Chemokine Receptors And ITP And HIV ThrombocytopeNational Heart, Lung, And Blood Institute1998–2002
- Endothelium Regulation Of Stem Cell Homing/ProliferationNational Heart, Lung, And Blood Institute1997–2000
- Regulation Of Thrombopoiesis By Bone Marrow EndotheliumNational Heart, Lung, And Blood Institute1994–1996
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