ScottBrianSnapperMDPhD

Inflammatory Bowel Disease

Chief, Division of GI, Hepatology, & Nutrition; Wolpow Family Chair in IBD Treatment and Research, Boston Children's Hospital; Egan Family Professor of Pediatrics in the Field of Transitional Medicine and Professor of Medicine, Harvard Medical School

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Office
300 Longwood Ave
Boston, MA 02115
Phone+1 617-919-4973

Education & Training

Massachusetts General HospitalFellowship, Gastroenterology, 1993 - 1997
Brigham and Women's HospitalResidency, Internal Medicine, 1990 - 1993
Albert Einstein College of MedicineClass of 1990

Certifications & Licensure

MA State Medical License 1992 - 2026
American Board of Internal Medicine Gastroenterology

Awards, Honors, & Recognition

Elected Member The American Society for Clinical Investigation, 2007

Clinical Trials

Oral OKT3 for the Treatment of Active Ulcerative Colitis Start of enrollment: 2011 Apr 07
Completed
Phase 1, Phase 2
Low Dose IL-2 for Ulcerative Colitis Start of enrollment: 2015 Feb 01
Completed
Phase 1
Low Dose IL-2 for the Treatment of Crohn's Disease Start of enrollment: 2021 Mar 11
Recruiting
Phase 1, Phase 2

Publications & Presentations

PubMed

1 citations
Human ITGAV variants are associated with immune dysregulation, brain abnormalities, and colitis.
Sina Ghasempour, Neil Warner, Rei Guan, Marco M Rodari, Danton Ivanochko
The Journal of Experimental Medicine. 2024-12-02
Hospital-wide access to genomic data advanced pediatric rare disease research and clinical outcomes.
Courtney E French, Nancy C Andrews, Alan H Beggs, Philip M Boone, Catherine A Brownstein
NPJ Genomic Medicine. 2024-12-02
Comprehensive evaluation and practical guideline of gating methods for high-dimensional cytometry data: manual gating, unsupervised clustering, and auto-gating.
Peng Liu, Yuchen Pan, Hung-Ching Chang, Wenjia Wang, Yusi Fang
Briefings in Bioinformatics. 2024-11-22

Journal Articles

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte–Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn’s Disease
Lee A Denson, Bruce J Aronow, Barbara S Kirschner, Joshua D Noe, Melvin B Heyman, Ramnik J Xavier, Robert N Baldassano, Jeffrey S Hyams, Subra Kugathasan, Wallace V Cr..., Inflammatory Bowel Diseases
Mucosal Gene Expression in Pediatric and Adult Patients with Ulcerative Colitis Permits Modeling of Ideal Biopsy Collection Strategy for Transcriptomic Analysis
Athos Bousvaros, Scott B Snapper, Jodie Ouahed, Inflammatory Bowel Diseases
The Treatment of Inflammatory Bowel Disease in Patients with Selected Primary Immunodeficiencies
Scott Snapper, MD, Journal of Clinical Immunology

Other

Increased Risk for Malignancies in 131 Affected CTLA4 Mutation Carriers
Scott Snapper, MD, Frontiers in Neurology
https://www.doximity.com/articles/50e86467-0edf-46ac-a42c-04b98941286b
UpToDate, Wolters Kluwer Health - 2011-04-29
Increased Risk for Malignancies in 131 Affected CTLA4 Mutation Carriers
Scott Snapper, MD, Frontiers in Neurology
https://www.doximity.com/articles/50e86467-0edf-46ac-a42c-04b98941286b
UpToDate, Wolters Kluwer Health - 2012-01-09

Authored Content

CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and ThrombosisJune 2017

Press Mentions

Pandion Therapeutics Announces Positive Top-Line Phase 1a Clinical Data Showing PT101 Was Well-Tolerated and Selectively Expanded Regulatory T CellsJanuary 4th, 2021
Pandion Shares Get a Lift from Positive Top-Line Data in Phase 1a Autoimmune Disease TrialJanuary 4th, 2021
From Bench to Bedside: A Promising Option for Unremitting Ulcerative ColitisJuly 20th, 2023

Grant Support

Exploring Regulatory T Cell Dysfunction In A Murine Model Of ColitisNational Institute Of Allergy And Infectious Diseases2011–2012
Deciphering The Role Of WASP Family Proteins In T Cell FunctionNational Heart, Lung, And Blood Institute2010–2011
Exploring Regulatory T Cell Dysfunction In A Murine Model Of ColitisNational Institute Of Allergy And Infectious Diseases2009–2010
Exploring Regulatory T Cell Dysfunction In A Murine Model Of ColitisNational Institute Of Allergy And Infectious Diseases2008
Cytoskeletal-Pathogen Interactions In Shigella InfectionNational Institute Of Allergy And Infectious Diseases2003–2007
The Pathogenesis Of Colitis In A Novel TH2 Model Of IBDNational Institute Of Allergy And Infectious Diseases2002–2004
Molecular And Genetic Analysis Of A Blood Cell DiseaseNational Heart, Lung, And Blood Institute1997–2001