ScottBrianSnapperMDPhD
Gastroenterology • Boston, MAInflammatory Bowel Disease
Chief, Division of GI, Hepatology, & Nutrition; Wolpow Family Chair in IBD Treatment and Research, Boston Children's Hospital; Egan Family Professor of Pediatrics in the Field of Transitional Medicine and Professor of Medicine, Harvard Medical School
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Office
300 Longwood Ave
Boston, MA 02115Phone+1 617-919-4973
Education & Training
Massachusetts General HospitalFellowship, Gastroenterology, 1993 - 1997
Brigham and Women's HospitalResidency, Internal Medicine, 1990 - 1993
Albert Einstein College of MedicineClass of 1990
Certifications & Licensure
MA State Medical License 1992 - 2024- American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2007
Clinical Trials
- Oral OKT3 for the Treatment of Active Ulcerative Colitis Start of enrollment: 2011 Apr 07
- Low Dose IL-2 for Ulcerative Colitis Start of enrollment: 2015 Feb 01
- Low Dose IL-2 for the Treatment of Crohn's Disease Start of enrollment: 2021 Mar 11
Publications & Presentations
PubMed
- 179 citationsIncidence, outcomes, and health services burden of very early onset inflammatory bowel disease.Eric I Benchimol, David R. Mack, Geoffrey C. Nguyen, Scott B. Snapper, Wenbin Li
Gastroenterology. 2014-10-01 - 79 citationsVariants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel DiseaseQi Li, Cheng Hiang Lee, Lauren A. Peters, Lucas A. Mastropaolo, Cornelia Thoeni
Gastroenterology. 2016-05-01 - 814 citationsAnti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages.W. K. Eddie Ip, Namiko Hoshi, Dror S. Shouval, Scott B. Snapper, Ruslan Medzhitov
Science. 2017-05-05
Journal Articles
- Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte–Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn’s DiseaseLee A Denson, Bruce J Aronow, Barbara S Kirschner, Joshua D Noe, Melvin B Heyman, Ramnik J Xavier, Robert N Baldassano, Jeffrey S Hyams, Subra Kugathasan, Wallace V Cr..., Inflammatory Bowel Diseases
- Mucosal Gene Expression in Pediatric and Adult Patients with Ulcerative Colitis Permits Modeling of Ideal Biopsy Collection Strategy for Transcriptomic AnalysisAthos Bousvaros, Scott B Snapper, Jodie Ouahed, Inflammatory Bowel Diseases
- The Treatment of Inflammatory Bowel Disease in Patients with Selected Primary ImmunodeficienciesScott Snapper, MD, Journal of Clinical Immunology
Other
- Increased Risk for Malignancies in 131 Affected CTLA4 Mutation CarriersScott Snapper, MD, Frontiers in Neurology
https://www.doximity.com/articles/50e86467-0edf-46ac-a42c-04b98941286b
UpToDate, Wolters Kluwer Health - 2011-04-29 - Increased Risk for Malignancies in 131 Affected CTLA4 Mutation CarriersScott Snapper, MD, Frontiers in Neurology
https://www.doximity.com/articles/50e86467-0edf-46ac-a42c-04b98941286b
UpToDate, Wolters Kluwer Health - 2012-01-09
Authored Content
- CD55 Deficiency, Early-Onset Protein-Losing Enteropathy, and ThrombosisJune 2017
Press Mentions
Pandion Therapeutics Announces Positive Top-Line Phase 1a Clinical Data Showing PT101 Was Well-Tolerated and Selectively Expanded Regulatory T CellsJanuary 4th, 2021- Pandion Shares Get a Lift from Positive Top-Line Data in Phase 1a Autoimmune Disease TrialJanuary 4th, 2021
- From Bench to Bedside: A Promising Option for Unremitting Ulcerative ColitisJuly 20th, 2023
Grant Support
- Exploring Regulatory T Cell Dysfunction In A Murine Model Of ColitisNational Institute Of Allergy And Infectious Diseases2011–2012
- Deciphering The Role Of WASP Family Proteins In T Cell FunctionNational Heart, Lung, And Blood Institute2010–2011
- Exploring Regulatory T Cell Dysfunction In A Murine Model Of ColitisNational Institute Of Allergy And Infectious Diseases2009–2010
- Exploring Regulatory T Cell Dysfunction In A Murine Model Of ColitisNational Institute Of Allergy And Infectious Diseases2008
- Cytoskeletal-Pathogen Interactions In Shigella InfectionNational Institute Of Allergy And Infectious Diseases2003–2007
- The Pathogenesis Of Colitis In A Novel TH2 Model Of IBDNational Institute Of Allergy And Infectious Diseases2002–2004
- Molecular And Genetic Analysis Of A Blood Cell DiseaseNational Heart, Lung, And Blood Institute1997–2001
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