ScottAArmstrongMD

PubMed

• 1 citations
  CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype-specific Vulnerability in IDH2- and TET2-mutant Cells.
  Michael R Waarts, Shoron Mowla, Meaghan Boileau, Anthony R Martinez Benitez, Junya Sango
  Cancer Discovery. 2024-10-04
• 6 citations
  Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias.
  Min Chul Kwon, Jan Willem Thuring, Olivier Querolle, Xuedong Dai, Tinne Verhulst
  Blood. 2024-09-12
• 3 citations
  A MOZ-TIF2 leukemia mouse model displays KAT6-dependent H3K23 propionylation and overexpression of a set of active developmental genes.
  Anne E Smolko, Daniel W Sullivan, Sarah Naomi Olsen, Hyuckjoon Kang, Samuel D Whedon
  Proceedings of the National Academy of Sciences of the United States of America. 2024-06-25

Journal Articles

• Article HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis  
  Ross L Levine, Jay L Hess, Sheng Cai, Scott A Armstrong, ScienceDirect

Abstracts/Posters

• Rationale for Targeting BCL6 in MLL-Rearranged B-ALL
  Scott A. Armstrong, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Leukemia Cell of Origin Influences p53 Activity and Therapeutic Sensitivity Via an Evi1-Dependent Mechanism
  Scott A. Armstrong, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• A Phase Ib/II Study of the Histone Methyltransferase Inhibitor Pinometostat in Combination with Azacitidine in Patients with 11q23-Rearranged Acute Myeloid Leukemia
  Scott A. Armstrong, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
• Tudor Domain-Focused CRISPR Dropout Screen Identifies SGF29 As a Novel Essential Gene in MLL-Rearranged Leukemias
  Scott A. Armstrong, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
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Lectures

• Biochemical and Genetic Insights Into MLL/11q23 Translocation Leukemia 
  60th American Society of Hematology Annual Meeting - 12/2/2018
• High-Density CRISPR Scan Identifies Functional Regions of DOT1L That Mediate Therapeutic Response in MLL-r Leukemia 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018